Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 227
- 0 vs. Q1 2025
- Shares held
- 66.5M
- +1.72M (+2.7%) vs. Q1 2025
- Total value
- $4.20B
- +$767.9M (+22.3%) vs. Q1 2025
- New holders
- 33
- 93 more added
- Sold out
- 33
- 74 more reduced
1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State Board of Administration of Florida Retirement System | 14,670 | $927.0K | 0.00% | 00.0% | Unchanged |
| Atom Investors LP | 14,866 | $939.4K | 0.08% | −96−0.6% | Reduced |
| Harvest Investment Services, LLC | 15,466 | $977.3K | 0.22% | +15,466 | New |
| Handelsbanken Fonder AB | 15,521 | $981.0K | 0.00% | −1,500−8.8% | Reduced |
| Victory Capital Management Inc | 16,241 | $1.03M | 0.00% | −1,085−6.3% | Reduced |
| Creative Planning | 17,222 | $1.09M | 0.00% | +4,889+39.6% | Added |
| STRS Ohio | 17,400 | $1.10M | 0.00% | −1,100−5.9% | Reduced |
| Captrust Financial Advisors | 17,471 | $1.10M | 0.00% | +114+0.7% | Added |
| Schroder Investment Management Group | 17,618 | $1.11M | 0.00% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 17,659 | $1.12M | 0.00% | 00.0% | Unchanged |
| Jump Financial, LLC | 17,671 | $1.12M | 0.01% | −24,089−57.7% | Reduced |
| Engineers Gate Manager LP | 17,676 | $1.12M | 0.01% | −4,207−19.2% | Reduced |
| Stifel Financial Corp | 18,177 | $1.15M | 0.00% | −310−1.7% | Reduced |
| Bellevue Group AG | 20,906 | $1.32M | 0.03% | +5,356+34.4% | Added |
| Wellington Management Group LLP | 22,425 | $1.42M | 0.00% | −1,133−4.8% | Reduced |
| D. E. Shaw & Co., Inc. | 24,278 | $1.53M | 0.00% | −59,591−71.1% | Reduced |
| Readystate Asset Management LP | 24,666 | $1.56M | 0.06% | +24,666 | New |
| SummitTX Capital, L.P. | 25,452 | $1.61M | 0.07% | +8,109+46.8% | Added |
| Intech Investment Management LLC | 27,443 | $1.73M | 0.02% | −6,450−19.0% | Reduced |
| HighVista Strategies LLC | 28,068 | $1.77M | 0.65% | −6,971−19.9% | Reduced |
| Wedge Capital Management L L P | 29,991 | $1.90M | 0.03% | −6,993−18.9% | Reduced |
| State of New Jersey Common Pension Fund D | 30,373 | $1.92M | 0.01% | −5,019−14.2% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 32,351 | $2.04M | 0.00% | −2,931−8.3% | Reduced |
| MetLife Investment Management | 32,395 | $2.05M | 0.01% | −19−0.1% | Reduced |
| SEI Investments Co | 33,145 | $2.09M | 0.00% | +764+2.4% | Added |
| Alps Advisors Inc | 34,178 | $2.16M | 0.01% | −12,029−26.0% | Reduced |
| Citigroup Inc | 34,324 | $2.17M | 0.00% | −51,882−60.2% | Reduced |
| Dark Forest Capital Management LP | 34,829 | $2.20M | 0.09% | +9,420+37.1% | Added |
| State of Wisconsin Investment Board | 35,708 | $2.26M | 0.01% | +2,683+8.1% | Added |
| Deutsche Bank AG | 36,779 | $2.32M | 0.00% | −7,000−16.0% | Reduced |
| Granahan Investment Management Inc | 41,172 | $2.60M | 0.11% | +41,172 | New |
| Wells Fargo & Company | 42,368 | $2.68M | 0.00% | −28,270−40.0% | Reduced |
| California State Teachers Retirement System | 42,917 | $2.71M | 0.00% | +196+0.5% | Added |
| ADAR1 Capital Management, LLC | 45,390 | $2.87M | 0.47% | +8,500+23.0% | Added |
| Silvercrest Asset Management Group LLC | 48,775 | $3.08M | 0.02% | +48,775 | New |
| AQR Capital Management LLC | 49,040 | $3.10M | 0.00% | +9,677+24.6% | Added |
| Nan Fung Group Holdings Ltd | 49,120 | $3.10M | 4.89% | 00.0% | Unchanged |
| Samsara BioCapital, LLC | 50,476 | $3.19M | 0.65% | −87,642−63.5% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 51,079 | $3.23M | 0.13% | −38,543−43.0% | Reduced |
| Rafferty Asset Management, LLC | 51,611 | $3.26M | 0.01% | −6,121−10.6% | Reduced |
| Axiom Investors LLC | 52,460 | $3.31M | 0.03% | +52,460 | New |
| Legal & General Group Plc | 52,681 | $3.33M | 0.00% | +1,523+3.0% | Added |
| Balyasny Asset Management LLC | 54,088 | $3.42M | 0.01% | −301,624−84.8% | Reduced |
| TD Asset Management Inc | 56,000 | $3.54M | 0.00% | +5,800+11.6% | Added |
| Kennedy Capital Management, Inc. | 57,217 | $3.62M | 0.09% | +2,287+4.2% | Added |
| New York State Common Retirement Fund | 58,618 | $3.70M | 0.00% | +41,768+247.9% | Added |
| Algert Global LLC | 60,219 | $3.81M | 0.08% | −1,242−2.0% | Reduced |
| Alliancebernstein L.P. | 61,470 | $3.88M | 0.00% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 64,577 | $4.08M | 0.04% | −109,245−62.8% | Reduced |
| Standard Life Aberdeen plc | 67,657 | $4.28M | 0.01% | −40,472−37.4% | Reduced |
| Manufacturers Life Insurance Company, The | 68,132 | $4.31M | 0.00% | +3,746+5.8% | Added |
| Invesco Ltd. | 68,924 | $4.36M | 0.00% | −192,978−73.7% | Reduced |
| Cinctive Capital Management LP | 70,937 | $4.48M | 0.25% | +66,581+1,528.5% | Added |
| First Trust Advisors LP | 73,714 | $4.66M | 0.00% | −16,065−17.9% | Reduced |
| Susquehanna International Group, LLP | 77,262 | $4.88M | 0.01% | −5,718−6.9% | Reduced |
| Schonfeld Strategic Advisors LLC | 77,983 | $4.93M | 0.04% | +20,833+36.5% | Added |
| Neuberger Berman Group LLC | 86,139 | $5.44M | 0.00% | +18,200+26.8% | Added |
| Harbor Capital Advisors, Inc. | 86,546 | $5.47M | 0.23% | +9,249+12.0% | Added |
| Rhumbline Advisers | 87,526 | $5.53M | 0.00% | +1,807+2.1% | Added |
| Swiss National Bank | 90,600 | $5.73M | 0.00% | +1,300+1.5% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 95,517 | $6.04M | 0.01% | +2,412+2.6% | Added |
| PDT Partners, LLC | 97,638 | $6.17M | 0.35% | −4,557−4.5% | Reduced |
| Lazard Asset Management LLC | 99,445 | $6.28M | 0.01% | −3,757−3.6% | Reduced |
| BNP Paribas Arbitrage, SA | 102,239 | $6.46M | 0.01% | +16,173+18.8% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 115,118 | $7.27M | 0.03% | +64,561+127.7% | Added |
| Panagora Asset Management Inc | 119,466 | $7.55M | 0.03% | −21,696−15.4% | Reduced |
| Integral Health Asset Management, LLC | 120,000 | $7.58M | 0.71% | +120,000 | New |
| Nuveen, LLC | 121,855 | $7.70M | 0.00% | −25,446−17.3% | Reduced |
| Logos Global Management LP | 130,000 | $8.21M | 1.10% | +130,000 | New |
| Russell Investments Group, Ltd. | 130,998 | $8.28M | 0.01% | +16,220+14.1% | Added |
| Point72 Asset Management, L.P. | 170,832 | $10.8M | 0.03% | +106,990+167.6% | Added |
| Ameriprise Financial Inc | 173,069 | $10.9M | 0.00% | +74,788+76.1% | Added |
| Artisan Partners Limited Partnership | 174,479 | $11.0M | 0.02% | +174,479 | New |
| StemPoint Capital LP | 176,752 | $11.2M | 3.60% | +142,936+422.7% | Added |
| Bank of New York Mellon Corp | 184,109 | $11.6M | 0.00% | +37,524+25.6% | Added |
| Royal Bank of Canada | 196,236 | $12.4M | 0.00% | +196,105+149,698.5% | Added |
| Millennium Management LLC | 198,110 | $12.5M | 0.01% | −19,269−8.9% | Reduced |
| Lord, Abbett & Co. LLC | 204,275 | $12.9M | 0.04% | +68,915+50.9% | Added |
| Norges Bank | 207,389 | $13.1M | 0.00% | −16,095−7.2% | Reduced |
| Bank of America Corp | 222,152 | $14.0M | 0.00% | +110,400+98.8% | Added |
| UBS Asset Management Americas Inc | 227,627 | $14.4M | 0.00% | +101,845+81.0% | Added |
| Assenagon Asset Management S.A. | 237,998 | $15.0M | 0.02% | +215,806+972.4% | Added |
| Qube Research & Technologies Ltd | 240,345 | $15.2M | 0.02% | +24,152+11.2% | Added |
| Voya Investment Management LLC | 244,003 | $15.4M | 0.02% | +158,154+184.2% | Added |
| OrbiMed Advisors LLC | 248,512 | $15.7M | 0.39% | −131,488−34.6% | Reduced |
| UBS Group AG | 252,582 | $16.0M | 0.00% | −19,526−7.2% | Reduced |
| Comerica Bank | 301,661 | $19.1M | 0.07% | +56,907+23.3% | Added |
| Clearbridge Investments, LLC | 312,445 | $19.7M | 0.02% | +312,445 | New |
| Candriam Luxembourg S.C.A. | 312,452 | $19.7M | 0.11% | +20,983+7.2% | Added |
| Renaissance Technologies LLC | 314,893 | $19.9M | 0.03% | +300,781+2,131.4% | Added |
| Voloridge Investment Management, LLC | 338,804 | $21.4M | 0.08% | −84,064−19.9% | Reduced |
| Adage Capital Partners GP, L.L.C. | 341,000 | $21.5M | 0.04% | +341,000 | New |
| Barclays PLC | 351,198 | $22.2M | 0.01% | +249,981+247.0% | Added |
| Marshall Wace, LLP | 376,242 | $23.8M | 0.03% | −158,861−29.7% | Reduced |
| Silverarc Capital Management, LLC | 400,772 | $25.3M | 5.18% | +63,167+18.7% | Added |
| Siren, L.L.C. | 409,742 | $25.9M | 1.34% | +132,209+47.6% | Added |
| Pictet Asset Management Holding SA | 416,115 | $26.3M | 0.03% | +156,769+60.4% | Added |
| Charles Schwab Investment Management Inc | 461,438 | $29.2M | 0.01% | +16,009+3.6% | Added |
| Opaleye Management Inc. | 475,000 | $30.0M | 6.07% | −15,000−3.1% | Reduced |
| Northern Trust Corp | 510,246 | $32.2M | 0.00% | −25,960−4.8% | Reduced |