Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 228
- +26 vs. Q4 2024
- Shares held
- 64.8M
- +48.3K (+0.1%) vs. Q4 2024
- Total value
- $3.44B
- −$189.2M (−5.2%) vs. Q4 2024
- New holders
- 45
- 86 more added
- Sold out
- 19
- 69 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| New York State Common Retirement Fund | 16,850 | $892.5K | 0.00% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 17,021 | $902.0K | 0.00% | 00.0% | Unchanged |
| Quantinno Capital Management LP | 17,086 | $905.0K | 0.01% | +966+6.0% | Added |
| Jefferies Financial Group Inc. | 17,100 | $905.8K | 0.02% | +17,100 | New |
| Victory Capital Management Inc | 17,326 | $917.8K | 0.00% | +174+1.0% | Added |
| SummitTX Capital, L.P. | 17,343 | $918.7K | 0.04% | +17,343 | New |
| Captrust Financial Advisors | 17,357 | $919.4K | 0.00% | +17,357 | New |
| Ensign Peak Advisors, Inc | 17,659 | $935.4K | 0.00% | 00.0% | Unchanged |
| Schroder Investment Management Group | 17,618 | $965.5K | 0.00% | +17,618 | New |
| Stifel Financial Corp | 18,487 | $979.3K | 0.00% | −1,029−5.3% | Reduced |
| STRS Ohio | 18,500 | $979.9K | 0.00% | +2,100+12.8% | Added |
| Fox Run Management, L.L.C. | 19,172 | $1.02M | 0.16% | +19,172 | New |
| SG Americas Securities, LLC | 19,667 | $1.04M | 0.00% | +19,667 | New |
| Engineers Gate Manager LP | 21,883 | $1.16M | 0.02% | +2,700+14.1% | Added |
| Assenagon Asset Management S.A. | 22,192 | $1.18M | 0.00% | +22,192 | New |
| Wellington Management Group LLP | 23,558 | $1.25M | 0.00% | −1,997−7.8% | Reduced |
| Squarepoint Ops LLC | 24,413 | $1.29M | 0.00% | +24,413 | New |
| Dark Forest Capital Management LP | 25,409 | $1.35M | 0.06% | +20,198+387.6% | Added |
| Corebridge Financial, Inc. | 26,821 | $1.42M | 0.01% | −399−1.5% | Reduced |
| Tudor Investment Corp Et Al | 29,513 | $1.56M | 0.01% | +14,268+93.6% | Added |
| XTX Topco Ltd | 29,949 | $1.59M | 0.08% | +22,344+293.8% | Added |
| SEI Investments Co | 32,381 | $1.72M | 0.00% | −1,141−3.4% | Reduced |
| MetLife Investment Management | 32,414 | $1.72M | 0.01% | −1,084−3.2% | Reduced |
| State of Wisconsin Investment Board | 33,025 | $1.75M | 0.00% | +763+2.4% | Added |
| StemPoint Capital LP | 33,816 | $1.79M | 0.57% | −174,200−83.7% | Reduced |
| Intech Investment Management LLC | 33,893 | $1.80M | 0.02% | +5,801+20.7% | Added |
| HighVista Strategies LLC | 35,039 | $1.86M | 0.72% | −2,387−6.4% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 35,282 | $1.87M | 0.00% | +2,126+6.4% | Added |
| State of New Jersey Common Pension Fund D | 35,392 | $1.87M | 0.01% | +388+1.1% | Added |
| Walleye Capital LLC | 35,828 | $1.90M | 0.02% | −108,514−75.2% | Reduced |
| ADAR1 Capital Management, LLC | 36,890 | $1.95M | 0.38% | +5,949+19.2% | Added |
| Wedge Capital Management L L P | 36,984 | $1.96M | 0.04% | −11,427−23.6% | Reduced |
| Principal Financial Group Inc | 37,156 | $1.97M | 0.00% | +272+0.7% | Added |
| Trexquant Investment LP | 38,724 | $2.05M | 0.02% | +30,926+396.6% | Added |
| AQR Capital Management LLC | 39,363 | $2.09M | 0.00% | +23,506+148.2% | Added |
| Aquatic Capital Management LLC | 41,476 | $2.20M | 0.06% | +32,253+349.7% | Added |
| Jump Financial, LLC | 41,760 | $2.21M | 0.03% | +41,760 | New |
| California State Teachers Retirement System | 42,721 | $2.26M | 0.00% | −812−1.9% | Reduced |
| Deutsche Bank AG | 43,779 | $2.32M | 0.00% | −4,966−10.2% | Reduced |
| EAM Investors, LLC | 45,108 | $2.39M | 0.41% | −17,970−28.5% | Reduced |
| Alps Advisors Inc | 46,207 | $2.45M | 0.01% | −3,493−7.0% | Reduced |
| Nan Fung Group Holdings Ltd | 49,120 | $2.60M | 2.12% | 00.0% | Unchanged |
| Diadema Partners LP | 50,000 | $2.65M | 2.12% | −25,000−33.3% | Reduced |
| Artia Global Partners LP | 50,000 | $2.65M | 0.78% | 00.0% | Unchanged |
| TD Asset Management Inc | 50,200 | $2.66M | 0.00% | +2,400+5.0% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 50,557 | $2.68M | 0.01% | +44,468+730.3% | Added |
| Legal & General Group Plc | 51,158 | $2.71M | 0.00% | −645−1.2% | Reduced |
| Kennedy Capital Management, Inc. | 54,930 | $2.91M | 0.07% | +54,930 | New |
| Schonfeld Strategic Advisors LLC | 57,150 | $3.03M | 0.02% | −2,550−4.3% | Reduced |
| Rafferty Asset Management, LLC | 57,732 | $3.06M | 0.01% | +7,338+14.6% | Added |
| Algert Global LLC | 61,461 | $3.26M | 0.08% | +19,910+47.9% | Added |
| Alliancebernstein L.P. | 61,470 | $3.26M | 0.00% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 63,842 | $3.38M | 0.01% | +63,842 | New |
| Manufacturers Life Insurance Company, The | 64,386 | $3.41M | 0.00% | +4,417+7.4% | Added |
| Neuberger Berman Group LLC | 67,939 | $3.60M | 0.00% | +67,939 | New |
| Citadel Advisors LLC | 70,068 | $3.71M | 0.00% | +29,649+73.4% | Added |
| Wells Fargo & Company | 70,638 | $3.74M | 0.00% | +33,314+89.3% | Added |
| Harbor Capital Advisors, Inc. | 77,297 | $4.09M | 0.19% | +47,045+155.5% | Added |
| Susquehanna International Group, LLP | 82,980 | $4.40M | 0.01% | +32,316+63.8% | Added |
| D. E. Shaw & Co., Inc. | 83,869 | $4.44M | 0.01% | +35,671+74.0% | Added |
| Rhumbline Advisers | 85,719 | $4.54M | 0.00% | +2,988+3.6% | Added |
| Voya Investment Management LLC | 85,849 | $4.55M | 0.01% | −11,320−11.6% | Reduced |
| BNP Paribas Arbitrage, SA | 86,066 | $4.56M | 0.00% | +817+1.0% | Added |
| Citigroup Inc | 86,206 | $4.57M | 0.00% | +16,429+23.5% | Added |
| Swiss National Bank | 89,300 | $4.73M | 0.00% | −900−1.0% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 89,622 | $4.75M | 0.21% | −9,825−9.9% | Reduced |
| First Trust Advisors LP | 89,779 | $4.76M | 0.00% | −28,558−24.1% | Reduced |
| Jane Street Group, LLC | 91,118 | $4.83M | 0.01% | +32,703+56.0% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 93,105 | $4.93M | 0.01% | +17,021+22.4% | Added |
| Ameriprise Financial Inc | 98,281 | $5.21M | 0.00% | +44,914+84.2% | Added |
| Barclays PLC | 101,217 | $5.36M | 0.00% | −34,180−25.2% | Reduced |
| PDT Partners, LLC | 102,195 | $5.41M | 0.38% | +58,612+134.5% | Added |
| Lazard Asset Management LLC | 103,202 | $5.46M | 0.01% | −3,059−2.9% | Reduced |
| Standard Life Aberdeen plc | 108,129 | $5.73M | 0.01% | +27,612+34.3% | Added |
| Bank of America Corp | 111,752 | $5.92M | 0.00% | +7,264+7.0% | Added |
| Russell Investments Group, Ltd. | 114,778 | $6.08M | 0.01% | +113,781+11,412.3% | Added |
| UBS Asset Management Americas Inc | 125,782 | $6.66M | 0.00% | −92,762−42.4% | Reduced |
| Lord, Abbett & Co. LLC | 135,360 | $7.17M | 0.03% | −25,291−15.7% | Reduced |
| Samsara BioCapital, LLC | 138,118 | $7.32M | 1.30% | −34,529−20.0% | Reduced |
| Panagora Asset Management Inc | 141,162 | $7.48M | 0.04% | +141,162 | New |
| JPMorgan Chase & Co | 143,640 | $7.61M | 0.00% | −120,945−45.7% | Reduced |
| Bank of New York Mellon Corp | 146,585 | $7.76M | 0.00% | −1,661−1.1% | Reduced |
| Nuveen, LLC | 147,301 | $7.80M | 0.00% | +147,301 | New |
| Cormorant Asset Management, LP | 150,000 | $7.95M | 0.60% | −250,000−62.5% | Reduced |
| Cubist Systematic Strategies, LLC | 173,822 | $9.21M | 0.12% | +173,822 | New |
| Qube Research & Technologies Ltd | 216,193 | $11.5M | 0.02% | +120,958+127.0% | Added |
| Millennium Management LLC | 217,379 | $11.5M | 0.01% | +202,120+1,324.6% | Added |
| Norges Bank | 223,484 | $11.8M | 0.00% | +17,835+8.7% | Added |
| Comerica Bank | 244,754 | $13.0M | 0.05% | +227,641+1,330.2% | Added |
| Pictet Asset Management Holding SA | 259,346 | $13.9M | 0.02% | −116,003−30.9% | Reduced |
| Invesco Ltd. | 261,902 | $13.9M | 0.00% | −40,944−13.5% | Reduced |
| UBS Group AG | 272,108 | $14.4M | 0.00% | +17,844+7.0% | Added |
| Siren, L.L.C. | 277,533 | $14.7M | 0.83% | +277,533 | New |
| Candriam Luxembourg S.C.A. | 291,469 | $15.4M | 0.10% | −40,923−12.3% | Reduced |
| Franklin Resources Inc | 326,160 | $17.3M | 0.01% | +57,955+21.6% | Added |
| Silverarc Capital Management, LLC | 337,605 | $17.9M | 3.74% | +63,709+23.3% | Added |
| Balyasny Asset Management LLC | 355,712 | $18.8M | 0.05% | +217,349+157.1% | Added |
| OrbiMed Advisors LLC | 380,000 | $20.1M | 0.48% | −20,000−5.0% | Reduced |
| Voloridge Investment Management, LLC | 422,868 | $22.4M | 0.08% | +42,331+11.1% | Added |
| Charles Schwab Investment Management Inc | 445,429 | $23.6M | 0.00% | +5,179+1.2% | Added |