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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 305 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2024

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
176
+12 vs. Q2 2024
Shares held
67.7M
+5.14M (+8.2%) vs. Q2 2024
Total value
$3.55B
+$976.9M (+38.0%) vs. Q2 2024
New holders
31
61 more added
Sold out
19
54 more reduced

1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 176 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 305 institutions
Value heldQ3 2024: $3.55B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026305$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q2 2024.

Institutions holding RYTM in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Citigroup Inc41,197$2.16M0.00%+21,205+106.1%Added
StemPoint Capital LP41,268$2.16M0.65%+41,268New
Harbor Capital Advisors, Inc.41,368$2.17M0.09%+6,741+19.5%Added
Ameriprise Financial Inc41,887$2.19M0.00%+1,472+3.6%Added
California State Teachers Retirement System43,916$2.30M0.00%−841−1.9%Reduced
Manufacturers Life Insurance Company, The48,703$2.55M0.00%−588−1.2%Reduced
Wedge Capital Management L L P48,844$2.56M0.04%−14,353−22.7%Reduced
Nan Fung Group Holdings Ltd49,120$2.57M2.22%00.0%Unchanged
FMR LLC50,295$2.63M0.00%+22,306+79.7%Added
Legal & General Group Plc50,852$2.66M0.00%+1,081+2.2%Added
Algert Global LLC54,171$2.84M0.08%−49,961−48.0%Reduced
JGP Global Gestao de Recursos Ltda.56,378$2.95M5.78%+50,564+869.7%Added
Alliancebernstein L.P.59,570$3.12M0.00%−1,500−2.5%Reduced
Rafferty Asset Management, LLC64,576$3.38M0.01%−7,986−11.0%Reduced
Nisa Investment Advisors, LLC66,240$3.47M0.02%−308,107−82.3%Reduced
Norges Bank66,276$3.47M0.00%+23,038+53.3%Added
Canada Pension Plan Investment Board67,000$3.51M0.00%−350,000−83.9%Reduced
First Trust Advisors LP70,762$3.71M0.00%−20,248−22.2%Reduced
UBS Group AG76,634$4.01M0.00%+10,692+16.2%Added
Ghost Tree Capital, LLC78,842$4.13M1.41%−38,546−32.8%Reduced
Rhumbline Advisers80,714$4.23M0.00%−2,349−2.8%Reduced
JPMorgan Chase & Co81,592$4.27M0.00%−58,554−41.8%Reduced
Clearbridge Investments, LLC87,424$4.58M0.00%−684−0.8%Reduced
Swiss National Bank89,300$4.68M0.00%+600+0.7%Added
Hennion & Walsh Asset Management, Inc.100,961$5.29M0.25%+4,583+4.8%Added
Lord, Abbett & Co. LLC102,646$5.38M0.02%+55+0.1%Added
Citadel Advisors LLC102,778$5.38M0.01%+102,778New
Voya Investment Management LLC102,832$5.39M0.01%+65,021+172.0%Added
Bank of America Corp106,250$5.57M0.00%+14,207+15.4%Added
Barclays PLC106,397$5.57M0.00%+52,766+98.4%Added
Jane Street Group, LLC109,186$5.72M0.01%−37,314−25.5%Reduced
Standard Life Aberdeen plc112,804$5.91M0.01%00.0%Unchanged
Great Lakes Advisors, LLC136,950$7.17M0.06%+136,950New
Woodline Partners LP143,823$7.53M0.06%+99,576+225.0%Added
Nuveen Asset Management, LLC147,875$7.75M0.00%−1,244−0.8%Reduced
Bank of New York Mellon Corp148,926$7.80M0.00%−42,945−22.4%Reduced
Samsara BioCapital, LLC172,647$9.04M1.74%00.0%Unchanged
UBS Asset Management Americas Inc225,373$11.8M0.00%−11,058−4.7%Reduced
Franklin Resources Inc259,416$13.0M0.00%+26,739+11.5%Added
Silverarc Capital Management, LLC255,578$13.4M3.02%+70,916+38.4%Added
Invesco Ltd.264,417$13.9M0.00%−12,283−4.4%Reduced
Sofinnova Investments, Inc.276,678$14.5M1.20%+276,678New
Pictet Asset Management Holding SA329,339$17.3M0.02%−472,457−58.9%Reduced
National Bank of Canada341,507$17.9M0.02%−62,735−15.5%Reduced
Voloridge Investment Management, LLC353,323$18.5M0.07%−108,865−23.6%Reduced
Candriam Luxembourg S.C.A.395,377$20.7M0.12%+123,979+45.7%Added
Cormorant Asset Management, LP400,000$21.0M1.11%−75,000−15.8%Reduced
Marshall Wace, LLP406,615$21.3M0.03%+299,806+280.7%Added
Charles Schwab Investment Management Inc433,866$22.7M0.00%+5,908+1.4%Added
OrbiMed Advisors LLC435,900$22.8M0.42%−268,942−38.2%Reduced
Morgan Stanley464,604$24.3M0.00%−11,047−2.3%Reduced
Northern Trust Corp498,466$26.1M0.00%−982−0.2%Reduced
Opaleye Management Inc.500,000$26.2M4.37%−15,000−2.9%Reduced
Price T Rowe Associates Inc550,530$28.8M0.00%+24,588+4.7%Added
Janus Henderson Group PLC598,122$31.3M0.02%+4,480+0.8%Added
Hood River Capital Management LLC614,598$32.2M0.52%+614,598New
Loomis Sayles & Co L P636,628$33.4M0.04%+636,628New
Commodore Capital LP650,000$34.1M2.13%−575,000−46.9%Reduced
Checkpoint Capital L.P.663,381$34.8M17.24%−258,719−28.1%Reduced
Healthcare of Ontario Pension Plan Trust Fund1,111,043$58.2M0.14%+143,800+14.9%Added
Alkeon Capital Management LLC1,167,700$61.2M0.34%+167,700+16.8%Added
Rock Springs Capital Management LP1,228,093$64.3M2.09%−52,400−4.1%Reduced
Geode Capital Management, LLC1,256,188$65.8M0.01%+3,499+0.3%Added
Driehaus Capital Management LLC1,299,490$68.1M0.58%+117,120+9.9%Added
Polar Capital Holdings Plc1,500,000$78.6M0.46%00.0%Unchanged
Federated Hermes, Inc.1,663,900$87.2M0.19%+3,116+0.2%Added
State Street Corp1,993,166$104.4M0.00%−10,716−0.5%Reduced
Frazier Life Sciences Management, L.P.2,416,952$126.6M5.08%+45,648+1.9%Added
NEA Management Company, LLC2,909,956$152.5M8.31%00.0%Unchanged
Vanguard Group Inc3,447,911$180.6M0.00%+87,216+2.6%Added
Perceptive Advisors LLC3,560,214$186.5M4.00%+113,635+3.3%Added
Goldman Sachs Group Inc3,879,796$203.3M0.04%−1,408,839−26.6%Reduced
Ra Capital Management, L.P.6,084,412$318.8M3.68%00.0%Unchanged
Baker Bros. Advisors LP6,398,366$335.2M3.47%+10.0%Added
BlackRock, Inc.6,889,258$360.9M0.01%+6,889,258New
Primecap Management Co7,216,911$378.1M0.28%−95,480−1.3%Reduced
Artisan Partners Limited Partnership0$00.00%−271,267−100.0%Sold out
Rice Hall James & Associates, LLC0$00.00%−93,081−100.0%Sold out
Caption Management, LLC0$00.00%−44,984−100.0%Sold out
Atom Investors LP0$00.00%−26,629−100.0%Sold out
Squarepoint Ops LLC0$00.00%−26,243−100.0%Sold out
GTS Securities LLC0$00.00%−23,136−100.0%Sold out
Parkwood LLC0$00.00%−16,387−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−13,000−100.0%Sold out
Kennedy Capital Management, Inc.0$00.00%−11,154−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−9,340−100.0%Sold out
Toroso Investments, LLC0$00.00%−9,011−100.0%Sold out
Omers Administration Corp0$00.00%−7,800−100.0%Sold out
Group One Trading, L.P.0$00.00%−4,991−100.0%Sold out
Allianz SE0$00.00%−1,350−100.0%Sold out
ORG Partners LLC0$00.00%−1,206−100.0%Sold out
Tucker Asset Management LLC0$00.00%−1,000−100.0%Sold out
Pacer Advisors, Inc.0$00.00%−413−100.0%Sold out
Mather Group, LLC.0$00.00%−65−100.0%Sold out
Innealta Capital, LLC0$00.00%−7−100.0%Sold out
BlackRock Inc.––––Not filed