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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2023

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
144
+28 vs. Q2 2023
Shares held
68.1M
+1.92M (+2.9%) vs. Q2 2023
Total value
$1.56B
+$470.0M (+43.0%) vs. Q2 2023
New holders
40
48 more added
Sold out
12
39 more reduced

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 144 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ3 2023: $1.56B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q2 2023.

Institutions holding RYTM in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Wellington Management Group LLP137,443$3.15M0.00%−2,778−2.0%Reduced
Nuveen Asset Management, LLC141,585$3.25M0.00%−56,858−28.7%Reduced
Jane Street Group, LLC144,002$3.30M0.01%+67,978+89.4%Added
ExodusPoint Capital Management, LP152,443$3.50M0.04%+136,762+872.2%Added
Rice Hall James & Associates, LLC157,426$3.61M0.23%−1,533−1.0%Reduced
Rafferty Asset Management, LLC162,804$3.73M0.02%−96,540−37.2%Reduced
Healthcare of Ontario Pension Plan Trust Fund177,000$4.06M0.02%+177,000New
Bank of New York Mellon Corp177,376$4.07M0.00%−10,420−5.5%Reduced
Clearbridge Investments, LLC182,825$4.19M0.00%+182,825New
Hudson Bay Capital Management LP207,500$4.76M0.05%+207,500New
Price T Rowe Associates Inc210,352$4.82M0.00%−12,885−5.8%Reduced
Barclays PLC241,261$5.53M0.00%+111,033+85.3%Added
Citadel Advisors LLC255,433$5.86M0.01%+65,901+34.8%Added
Silverarc Capital Management, LLC260,537$5.97M2.23%+144,369+124.3%Added
Driehaus Capital Management LLC274,524$6.29M0.08%+251,531+1,093.9%Added
UBS Asset Management Americas Inc337,264$7.73M0.00%+131,229+63.7%Added
Samsara BioCapital, LLC345,293$7.92M2.42%00.0%Unchanged
Perceptive Advisors LLC380,828$8.73M0.29%+380,828New
Charles Schwab Investment Management Inc384,748$8.82M0.00%+34,189+9.8%Added
Logos Global Management LP400,000$9.17M1.31%+400,000New
Assenagon Asset Management S.A.407,290$9.34M0.03%−135,920−25.0%Reduced
Morgan Stanley436,408$10.0M0.00%+333,227+323.0%Added
Northern Trust Corp504,022$11.6M0.00%+9,820+2.0%Added
OrbiMed Advisors LLC583,642$13.4M0.31%+583,642New
Opaleye Management Inc.653,000$15.0M4.92%−82,000−11.2%Reduced
Cormorant Asset Management, LP850,000$19.5M1.14%+250,000+41.7%Added
FMR LLC868,474$19.9M0.00%+166,940+23.8%Added
Geode Capital Management, LLC1,045,057$24.0M0.00%+71,707+7.4%Added
Janus Henderson Group PLC1,065,745$24.4M0.02%−12,462−1.2%Reduced
VR Adviser, LLC1,090,000$25.0M2.63%00.0%Unchanged
Rock Springs Capital Management LP1,597,123$36.6M0.98%00.0%Unchanged
Alkeon Capital Management LLC1,725,167$39.5M0.25%00.0%Unchanged
Commodore Capital LP2,075,000$47.6M5.56%+2,075,000New
Federated Hermes, Inc.2,341,335$53.7M0.14%−1,550,348−39.8%Reduced
State Street Corp2,365,856$54.2M0.00%−901,569−27.6%Reduced
Frazier Life Sciences Management, L.P.2,371,304$54.4M3.61%+204,082+9.4%Added
Polar Capital Holdings Plc2,500,000$57.3M0.43%+250,000+11.1%Added
NEA Management Company, LLC2,909,956$66.7M5.15%00.0%Unchanged
Vanguard Group Inc3,014,568$69.1M0.00%+85,139+2.9%Added
Goldman Sachs Group Inc5,160,541$118.3M0.03%−25,472−0.5%Reduced
Ra Capital Management, L.P.5,676,067$130.1M2.56%00.0%Unchanged
BlackRock Inc.6,199,882$142.1M0.00%−65,123−1.0%Reduced
Baker Bros. Advisors LP6,702,349$153.7M0.89%+204,082+3.1%Added
Primecap Management Co8,267,421$189.5M0.16%−31,896−0.4%Reduced
Braidwell LP0$00.00%−843,087−100.0%Sold out
Great Point Partners LLC0$00.00%−772,000−100.0%Sold out
Walleye Capital LLC0$00.00%−395,541−100.0%Sold out
Kynam Capital Management, LP0$00.00%−92,602−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−38,600−100.0%Sold out
Utah Retirement Systems0$00.00%−28,197−100.0%Sold out
Walleye Trading LLC0$00.00%−25,395−100.0%Sold out
E Fund Management Co., Ltd.0$00.00%−13,948−100.0%Sold out
Virtu Financial LLC0$00.00%−13,188−100.0%Sold out
HarbourVest Partners LLC0$00.00%−5,639−100.0%Sold out
Russell Investments Group, Ltd.0$00.00%−1,100−100.0%Sold out
Beaird Harris Wealth Management, LLC0$00.00%−49−100.0%Sold out