Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 187
- −1 vs. Q1 2026
- Shares held
- 106.6M
- +8.18M (+8.3%) vs. Q1 2026
- Total value
- $393.5M
- +$51.3M (+15.0%) vs. Q1 2026
- New holders
- 22
- 64 more added
- Sold out
- 23
- 67 more reduced
4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $340.4M |
| Q3 2025 | 167 | $512.0M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.5M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $266.0M |
| Q2 2024 | 122 | $354.2M |
| Q1 2024 | 115 | $469.7M |
| Q4 2023 | 105 | $433.7M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $616.9M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SG Americas Securities, LLC | 58,922 | $217.0K | 0.00% | +58,922 | New |
| Vanguard Asset Management, Ltd | 59,021 | $217.8K | 0.00% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 59,133 | $218.2K | 0.00% | −51,215−46.4% | Reduced |
| Jupiter Topco LLC | 60,900 | $224.4K | 0.00% | +60,900 | New |
| Bridgeway Capital Management, LLC | 64,800 | $239.1K | 0.00% | −70,000−51.9% | Reduced |
| BNP Paribas Arbitrage, SA | 66,101 | $243.9K | 0.00% | +31,688+92.1% | Added |
| Legal & General Group Plc | 66,444 | $245.2K | 0.00% | 00.0% | Unchanged |
| Profund Advisors LLC | 72,624 | $268.0K | 0.01% | −23,182−24.2% | Reduced |
| Los Angeles Capital Management LLC | 82,305 | $303.7K | 0.00% | +29,690+56.4% | Added |
| UBS Asset Management Americas Inc | 85,300 | $314.8K | 0.00% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 87,310 | $322.2K | 0.00% | +70,873+431.2% | Added |
| Squarepoint Ops LLC | 88,029 | $324.8K | 0.00% | −6,037−6.4% | Reduced |
| Barclays PLC | 88,058 | $324.9K | 0.00% | +24,285+38.1% | Added |
| Rockefeller Capital Management L.P. | 90,735 | $334.8K | 0.00% | −666−0.7% | Reduced |
| LPL Financial LLC | 92,174 | $340.1K | 0.00% | +25,750+38.8% | Added |
| TD Asset Management Inc | 94,148 | $347.4K | 0.00% | 00.0% | Unchanged |
| Milestone Asset Management, LLC | 100,035 | $369.1K | 0.06% | +100,035 | New |
| Palumbo Wealth Management LLC | 103,801 | $383.0K | 0.08% | +1,555+1.5% | Added |
| Steward Partners Investment Advisory, LLC | 108,290 | $399.6K | 0.00% | −9,166−7.8% | Reduced |
| Deutsche Bank AG | 114,472 | $422.4K | 0.00% | −42,968−27.3% | Reduced |
| FIL Ltd | 115,206 | $425.1K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 116,754 | $430.8K | 0.00% | +2,485+2.2% | Added |
| Renaissance Technologies LLC | 117,412 | $433.3K | 0.00% | −623,627−84.2% | Reduced |
| Virtus Investment Advisers, Inc. | 117,909 | $435.1K | 0.10% | +51,401+77.3% | Added |
| AQR Capital Management LLC | 117,998 | $435.4K | 0.00% | −436,937−78.7% | Reduced |
| ExodusPoint Capital Management, LP | 118,464 | $437.1K | 0.00% | +118,464 | New |
| Concurrent Investment Advisors, LLC | 131,722 | $486.1K | 0.00% | +57,545+77.6% | Added |
| Invesco Ltd. | 140,308 | $517.7K | 0.00% | +43,433+44.8% | Added |
| Alliancebernstein L.P. | 150,300 | $523.0K | 0.00% | +27,840+22.7% | Added |
| Rafferty Asset Management, LLC | 145,275 | $536.1K | 0.00% | −70,307−32.6% | Reduced |
| Bollard Group LLC | 151,136 | $558.0K | 0.02% | −210,000−58.1% | Reduced |
| California State Teachers Retirement System | 157,049 | $579.5K | 0.00% | +70,576+81.6% | Added |
| HRT Financial LP | 161,510 | $595.0K | 0.00% | −451,259−73.6% | Reduced |
| Price T Rowe Associates Inc | 162,325 | $599.0K | 0.00% | +28,570+21.4% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 162,338 | $599.5K | 0.00% | +39,875+32.6% | Added |
| Keystone Financial Group | 166,510 | $614.4K | 0.04% | +500+0.3% | Added |
| Green Alpha Advisors, LLC | 185,023 | $682.7K | 0.46% | −6,148−3.2% | Reduced |
| Citigroup Inc | 195,664 | $722.0K | 0.00% | +148,432+314.3% | Added |
| PEAK6 LLC | 208,057 | $767.7K | 0.02% | +208,057 | New |
| Swiss National Bank | 208,300 | $768.6K | 0.00% | +29,700+16.6% | Added |
| Jupiter Asset Management Ltd | 209,490 | $773.0K | 0.00% | +209,490 | New |
| Jain Global LLC | 215,218 | $794.2K | 0.01% | +215,218 | New |
| XTX Topco Ltd | 215,708 | $796.0K | 0.01% | +58,426+37.1% | Added |
| Marshall Wace, LLP | 216,841 | $800.1K | 0.00% | +74,884+52.8% | Added |
| Davy Global Fund Management Ltd | 225,799 | $833.2K | 0.05% | +20,410+9.9% | Added |
| Bank of New York Mellon Corp | 246,344 | $909.0K | 0.00% | −20,875−7.8% | Reduced |
| Wells Fargo & Company | 251,747 | $928.9K | 0.00% | −67,803−21.2% | Reduced |
| Nuveen, LLC | 275,931 | $1.02M | 0.00% | 00.0% | Unchanged |
| Wellington Management Group LLP | 304,444 | $1.12M | 0.00% | +26,324+9.5% | Added |
| Dimensional Fund Advisors LP | 304,678 | $1.12M | 0.00% | +156+0.1% | Added |
| HighTower Advisors, LLC | 340,365 | $1.26M | 0.00% | +1100.0% | Added |
| Millennium Management LLC | 427,097 | $1.58M | 0.00% | +427,097 | New |
| Chelsea Counsel Co | 449,060 | $1.66M | 0.70% | −13,280−2.9% | Reduced |
| Moore Capital Management, LP | 500,000 | $1.84M | 0.04% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 533,553 | $1.97M | 0.00% | +533,553 | New |
| Susquehanna International Group, LLP | 648,479 | $2.39M | 0.00% | −67,350−9.4% | Reduced |
| D. E. Shaw & Co., Inc. | 648,940 | $2.39M | 0.00% | −744,681−53.4% | Reduced |
| Alessandra Capital Management, LLC | 666,603 | $2.46M | 1.74% | +241,093+56.7% | Added |
| Morgan Stanley | 708,963 | $2.62M | 0.00% | +69,506+10.9% | Added |
| Vanguard Fiduciary Trust Co | 764,633 | $2.82M | 0.00% | +47,631+6.6% | Added |
| Greenwich Wealth Management LLC | 768,001 | $2.83M | 0.10% | +18,000+2.4% | Added |
| JPMorgan Chase & Co | 810,095 | $3.01M | 0.00% | −34,059−4.0% | Reduced |
| Northern Trust Corp | 912,597 | $3.37M | 0.00% | +25,881+2.9% | Added |
| Charles Schwab Investment Management Inc | 927,538 | $3.42M | 0.00% | +10,326+1.1% | Added |
| Vanguard Portfolio Management LLC | 961,826 | $3.55M | 0.00% | +99,622+11.6% | Added |
| Bank of America Corp | 981,335 | $3.62M | 0.00% | +404,331+70.1% | Added |
| Jump Financial, LLC | 1,240,429 | $4.58M | 0.04% | +1,240,429 | New |
| Farallon Capital Management, L.L.C. | 1,240,843 | $4.58M | 0.03% | 00.0% | Unchanged |
| Redmile Group, LLC | 1,389,632 | $5.13M | 0.34% | −201,200−12.6% | Reduced |
| Two Sigma Investments, LP | 1,524,511 | $5.63M | 0.00% | −48,300−3.1% | Reduced |
| FMR LLC | 1,761,884 | $6.50M | 0.00% | −7,592−0.4% | Reduced |
| ADAR1 Capital Management, LLC | 1,997,552 | $7.37M | 0.35% | +24,270+1.2% | Added |
| Citadel Advisors LLC | 2,054,543 | $7.58M | 0.00% | +1,718,185+510.8% | Added |
| Nikko Asset Management Americas, Inc. | 2,407,018 | $8.86M | 0.11% | −533,775−18.2% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 2,412,984 | $8.90M | 0.01% | −527,809−17.9% | Reduced |
| Geode Capital Management, LLC | 2,712,446 | $10.0M | 0.00% | −31,254−1.1% | Reduced |
| UBS Group AG | 2,794,689 | $10.3M | 0.00% | −93,729−3.2% | Reduced |
| Woodline Partners LP | 3,003,904 | $11.1M | 0.03% | +5910.0% | Added |
| Casdin Capital, LLC | 3,167,175 | $11.7M | 0.58% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 3,430,518 | $12.7M | 0.00% | +2,460,093+253.5% | Added |
| Balyasny Asset Management LLC | 3,969,082 | $14.6M | 0.03% | −154,283−3.7% | Reduced |
| Vanguard Capital Management LLC | 4,522,640 | $16.7M | 0.00% | +48,478+1.1% | Added |
| T. Rowe Price Investment Management, Inc. | 5,237,332 | $19.3M | 0.01% | −244,561−4.5% | Reduced |
| State Street Corp | 7,576,460 | $28.0M | 0.00% | +1,231,335+19.4% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 8,348,746 | $30.8M | 0.20% | +2,101,919+33.6% | Added |
| BlackRock, Inc. | 9,602,041 | $35.4M | 0.00% | +1,100,333+12.9% | Added |
| Alphabet Inc. | 16,562,498 | $61.1M | 0.06% | 00.0% | Unchanged |
| Elevate Capital Advisors, LLC | 0 | $0 | 0.00% | −151,069−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −61,546−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −54,230−100.0% | Sold out |
| VARCOV Co. | 0 | $0 | 0.00% | −41,964−100.0% | Sold out |
| Axq Capital, LP | 0 | $0 | 0.00% | −36,742−100.0% | Sold out |
| Transcend Wealth Collective, LLC | 0 | $0 | 0.00% | −30,070−100.0% | Sold out |
| Turtle Creek Wealth Advisors, LLC | 0 | $0 | 0.00% | −25,000−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −24,823−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −24,766−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −17,931−100.0% | Sold out |
| Martingale Asset Management L P | 0 | $0 | 0.00% | −14,848−100.0% | Sold out |
| Sterling Investment Advisors, Ltd. | 0 | $0 | 0.00% | −13,400−100.0% | Sold out |
| Mercer Global Advisors Inc | 0 | $0 | 0.00% | −12,305−100.0% | Sold out |