Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Opko Health, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 222
- −31 vs. Q1 2025
- Shares held
- 205.2M
- −36.9M (−15.2%) vs. Q1 2025
- Total value
- $270.4M
- −$130.9M (−32.6%) vs. Q1 2025
- New holders
- 17
- 56 more added
- Sold out
- 48
- 66 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Operose Advisors LLC | 32,000 | $42.2K | 0.01% | 00.0% | Unchanged |
| RSM US Wealth Management LLC | 33,757 | $44.6K | 0.00% | 00.0% | Unchanged |
| HSBC Holdings PLC | 34,939 | $46.3K | 0.00% | −1,913−5.2% | Reduced |
| Shell Asset Management Co | 37,028 | $49.0K | 0.00% | −3,969−9.7% | Reduced |
| Renaissance Technologies LLC | 38,100 | $50.3K | 0.00% | +38,100 | New |
| Wealth Enhancement Advisory Services, LLC | 36,994 | $50.3K | 0.00% | −37,712−50.5% | Reduced |
| Kestra Advisory Services, LLC | 38,807 | $51.2K | 0.00% | −11,500−22.9% | Reduced |
| HighTower Advisors, LLC | 38,906 | $51.4K | 0.00% | 00.0% | Unchanged |
| Brighton Jones LLC | 38,916 | $51.4K | 0.00% | +8,775+29.1% | Added |
| Norges Bank | 39,477 | $52.1K | 0.00% | −454,780−92.0% | Reduced |
| Mercer Global Advisors Inc | 39,534 | $52.2K | 0.00% | −15,423−28.1% | Reduced |
| RK Asset Management, LLC | 40,485 | $53.0K | 0.05% | 00.0% | Unchanged |
| Pensionmark Financial Group, LLC | 40,618 | $53.6K | 0.00% | 00.0% | Unchanged |
| Victory Capital Management Inc | 41,761 | $55.1K | 0.00% | +5,145+14.1% | Added |
| Captrust Financial Advisors | 41,927 | $55.3K | 0.00% | −6,555−13.5% | Reduced |
| Atom Investors LP | 43,282 | $57.1K | 0.01% | +2,522+6.2% | Added |
| CIBC World Markets Corp | 44,575 | $58.8K | 0.00% | −26,194−37.0% | Reduced |
| Prudential Financial Inc | 46,842 | $61.8K | 0.00% | +20,076+75.0% | Added |
| Farmers National Bank | 50,300 | $66.4K | 0.02% | 00.0% | Unchanged |
| Verition Fund Management LLC | 50,650 | $66.9K | 0.00% | −267,296−84.1% | Reduced |
| Transcend Wealth Collective, LLC | 50,851 | $67.1K | 0.01% | +10.0% | Added |
| Teacher Retirement System of Texas | 51,277 | $67.7K | 0.00% | −32,489−38.8% | Reduced |
| First Manhattan Co | 51,750 | $68.3K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 54,068 | $71.0K | 0.00% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 55,124 | $72.8K | 0.00% | −161,233−74.5% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 55,140 | $72.8K | 0.00% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 55,301 | $73.0K | 0.00% | 00.0% | Unchanged |
| Cim Investment Mangement Inc | 53,591 | $74.8K | 0.01% | +26,894+100.7% | Added |
| The PNC Financial Services Group, Inc. | 56,800 | $75.0K | 0.00% | 00.0% | Unchanged |
| Headlands Technologies LLC | 57,724 | $76.2K | 0.01% | +5,575+10.7% | Added |
| Kestra Private Wealth Services, LLC | 58,450 | $77.2K | 0.00% | 00.0% | Unchanged |
| Cetera Investment Advisers | 60,557 | $79.9K | 0.00% | +10.0% | Added |
| New York State Common Retirement Fund | 60,801 | $80.3K | 0.00% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 61,502 | $81.0K | 0.00% | 00.0% | Unchanged |
| Pictet Asset Management Holding SA | 65,495 | $86.5K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 66,170 | $87.3K | 0.00% | −19,200−22.5% | Reduced |
| Cascade Financial Partners, LLC | 66,490 | $87.8K | 0.01% | 00.0% | Unchanged |
| SIH Partners, LLLP | 69,419 | $91.6K | 0.01% | +69,419 | New |
| KLP Kapitalforvaltning AS | 74,000 | $97.7K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 74,184 | $97.9K | 0.00% | +5,139+7.4% | Added |
| Police & Firemen's Retirement System of New Jersey | 77,449 | $102.2K | 0.00% | 00.0% | Unchanged |
| State of Wyoming | 82,007 | $108.2K | 0.01% | +82,007 | New |
| XTX Topco Ltd | 84,907 | $112.1K | 0.00% | −224,383−72.5% | Reduced |
| Arizona State Retirement System | 88,194 | $116.4K | 0.00% | −9,689−9.9% | Reduced |
| 360 Financial, Inc. | 88,800 | $117.2K | 0.04% | +9,500+12.0% | Added |
| Hollencrest Capital Management | 90,000 | $118.8K | 0.01% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 92,434 | $122.0K | 0.00% | −209,427−69.4% | Reduced |
| Advisor Group Holdings, Inc. | 94,476 | $124.7K | 0.00% | −557,333−85.5% | Reduced |
| Ameriprise Financial Inc | 94,760 | $125.1K | 0.00% | +669+0.7% | Added |
| Intrepid Capital Management Inc | 100,000 | $132.0K | 0.05% | 00.0% | Unchanged |
| Phoenix Holdings Ltd. | 100,000 | $132.9K | 0.00% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 103,111 | $136.0K | 0.00% | +10.0% | Added |
| Ieq Capital, LLC | 109,219 | $144.2K | 0.00% | −74,144−40.4% | Reduced |
| Humankind Investments LLC | 109,299 | $144.3K | 0.04% | +62,886+135.5% | Added |
| Comerica Bank | 112,000 | $147.8K | 0.00% | 00.0% | Unchanged |
| Glenmede Investment Management, LP | 112,750 | $148.8K | 0.00% | +112,750 | New |
| Highline Wealth Partners LLC | 116,680 | $154.0K | 0.05% | 00.0% | Unchanged |
| Van Eck Associates Corp | 119,041 | $157.0K | 0.00% | +5,535+4.9% | Added |
| Csenge Advisory Group | 117,000 | $159.1K | 0.01% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 133,659 | $176.4K | 0.00% | +14,436+12.1% | Added |
| Manufacturers Life Insurance Company, The | 138,643 | $183.0K | 0.00% | +13,912+11.2% | Added |
| Intech Investment Management LLC | 141,624 | $186.9K | 0.00% | −62,693−30.7% | Reduced |
| Teton Advisors, Inc. | 142,000 | $187.4K | 0.11% | −2,500−1.7% | Reduced |
| Citigroup Inc | 167,111 | $220.6K | 0.00% | −96,790−36.7% | Reduced |
| Gabelli Funds LLC | 170,000 | $224.4K | 0.00% | 00.0% | Unchanged |
| Gamco Investors, Inc. Et Al | 175,000 | $231.0K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 176,260 | $232.7K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 198,148 | $261.6K | 0.00% | +8,954+4.7% | Added |
| Janus Henderson Group PLC | 206,314 | $271.3K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 206,375 | $272.0K | 0.00% | −145,901−41.4% | Reduced |
| Zazove Associates LLC | 207,600 | $274.0K | 0.02% | 00.0% | Unchanged |
| Citadel Advisors LLC | 217,395 | $287.0K | 0.00% | −1,639,131−88.3% | Reduced |
| MetLife Investment Management | 218,272 | $288.1K | 0.00% | +54,042+32.9% | Added |
| Deutsche Bank AG | 239,018 | $315.5K | 0.00% | −42,629−15.1% | Reduced |
| Tudor Investment Corp Et Al | 244,821 | $323.2K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 267,448 | $352.0K | 0.00% | +30,839+13.0% | Added |
| Wells Fargo & Company | 271,094 | $357.8K | 0.00% | +41,079+17.9% | Added |
| California State Teachers Retirement System | 324,117 | $427.8K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 355,682 | $469.5K | 0.00% | +5,584+1.6% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 391,664 | $517.0K | 0.00% | +190,319+94.5% | Added |
| Price T Rowe Associates Inc | 437,506 | $578.0K | 0.00% | −64,162−12.8% | Reduced |
| Alliancebernstein L.P. | 468,290 | $618.1K | 0.00% | −36,100−7.2% | Reduced |
| Rhumbline Advisers | 529,553 | $699.0K | 0.00% | +39,274+8.0% | Added |
| Commonwealth Equity Services, LLC | 554,398 | $732.0K | 0.00% | +74,568+15.5% | Added |
| Swiss National Bank | 577,355 | $762.1K | 0.00% | −83,800−12.7% | Reduced |
| BNP Paribas Arbitrage, SA | 581,671 | $767.8K | 0.00% | −309,474−34.7% | Reduced |
| JPMorgan Chase & Co | 630,355 | $832.1K | 0.00% | −1,870,977−74.8% | Reduced |
| Susquehanna International Group, LLP | 644,670 | $851.0K | 0.00% | −111,476−14.7% | Reduced |
| Two Sigma Advisers, LP | 648,297 | $855.8K | 0.00% | +96,600+17.5% | Added |
| Barclays PLC | 664,407 | $877.0K | 0.00% | +272,416+69.5% | Added |
| Millennium Management LLC | 695,780 | $918.4K | 0.00% | −5,691,131−89.1% | Reduced |
| Clearstead Advisors, LLC | 883,042 | $1.17M | 0.02% | 00.0% | Unchanged |
| Assenagon Asset Management S.A. | 935,100 | $1.23M | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 935,900 | $1.24M | 0.00% | −673,006−41.8% | Reduced |
| Tejara Capital Ltd | 946,090 | $1.25M | 0.58% | +85,746+10.0% | Added |
| Nuveen, LLC | 1,126,557 | $1.49M | 0.00% | −250,324−18.2% | Reduced |
| UBS Asset Management Americas Inc | 1,127,476 | $1.49M | 0.00% | +345,842+44.2% | Added |
| Bank of New York Mellon Corp | 1,148,906 | $1.52M | 0.00% | +128,385+12.6% | Added |
| PFG Investments, LLC | 1,265,125 | $1.67M | 0.10% | +47,765+3.9% | Added |
| Voya Investment Management LLC | 1,319,561 | $1.74M | 0.00% | +509,685+62.9% | Added |