Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Opko Health, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 255
- +21 vs. Q4 2024
- Shares held
- 242.1M
- +46.0M (+23.4%) vs. Q4 2024
- Total value
- $401.4M
- +$113.2M (+39.3%) vs. Q4 2024
- New holders
- 44
- 76 more added
- Sold out
- 23
- 57 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Exchange Traded Concepts, LLC | 338,948 | $562.7K | 0.01% | −12,948−3.7% | Reduced |
| Legal & General Group Plc | 350,098 | $581.2K | 0.00% | −20,340−5.5% | Reduced |
| SG Americas Securities, LLC | 352,276 | $585.0K | 0.00% | +352,276 | New |
| Barclays PLC | 391,991 | $650.7K | 0.00% | −524,377−57.2% | Reduced |
| X-Square Capital, LLC | 460,425 | $764.0K | 0.33% | +298,699+184.7% | Added |
| Commonwealth Equity Services, LLC | 479,830 | $797.0K | 0.00% | +45,795+10.6% | Added |
| Rhumbline Advisers | 490,279 | $813.9K | 0.00% | −28,544−5.5% | Reduced |
| Norges Bank | 494,257 | $820.5K | 0.00% | −633,211−56.2% | Reduced |
| Price T Rowe Associates Inc | 501,668 | $833.0K | 0.00% | +46,147+10.1% | Added |
| Alliancebernstein L.P. | 504,390 | $837.3K | 0.00% | +129,070+34.4% | Added |
| Jane Street Group, LLC | 549,338 | $911.9K | 0.00% | −2,257,583−80.4% | Reduced |
| Two Sigma Advisers, LP | 551,697 | $915.8K | 0.00% | +170,500+44.7% | Added |
| Advisor Group Holdings, Inc. | 651,809 | $1.08M | 0.00% | +119,983+22.6% | Added |
| Swiss National Bank | 661,155 | $1.10M | 0.00% | −24,300−3.5% | Reduced |
| Susquehanna International Group, LLP | 756,146 | $1.26M | 0.00% | +611,010+421.0% | Added |
| UBS Asset Management Americas Inc | 781,634 | $1.30M | 0.00% | +28,254+3.8% | Added |
| Voya Investment Management LLC | 809,876 | $1.34M | 0.00% | −445,158−35.5% | Reduced |
| Tejara Capital Ltd | 860,344 | $1.43M | 0.70% | −365,306−29.8% | Reduced |
| HRT Financial LP | 880,240 | $1.46M | 0.01% | +210,604+31.5% | Added |
| Clearstead Advisors, LLC | 883,042 | $1.47M | 0.02% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 891,145 | $1.48M | 0.00% | +839,296+1,618.7% | Added |
| Assenagon Asset Management S.A. | 935,100 | $1.56M | 0.00% | +78,362+9.1% | Added |
| Bank of New York Mellon Corp | 1,020,521 | $1.69M | 0.00% | −4,386−0.4% | Reduced |
| PFG Investments, LLC | 1,217,360 | $2.02M | 0.13% | +56,475+4.9% | Added |
| Gsa Capital Partners LLP | 1,343,701 | $2.23M | 0.20% | +261,495+24.2% | Added |
| Nuveen, LLC | 1,376,881 | $2.29M | 0.00% | +1,376,881 | New |
| Altshuler Shaham Ltd | 1,454,221 | $2.44M | 0.06% | +43,202+3.1% | Added |
| AQR Capital Management LLC | 1,608,906 | $2.67M | 0.00% | +1,324,988+466.7% | Added |
| Invesco Ltd. | 1,623,600 | $2.70M | 0.00% | +69,111+4.4% | Added |
| Two Sigma Investments, LP | 1,645,775 | $2.73M | 0.01% | −1,792−0.1% | Reduced |
| Y.D. More Investments Ltd | 1,772,947 | $2.97M | 0.26% | +377,179+27.0% | Added |
| Graham Capital Management, L.P. | 1,810,392 | $3.01M | 0.10% | +1,810,392 | New |
| AWM Investment Company, Inc. | 1,850,000 | $3.07M | 0.42% | +550,000+42.3% | Added |
| Citadel Advisors LLC | 1,856,526 | $3.08M | 0.00% | −1,353,764−42.2% | Reduced |
| Dimensional Fund Advisors LP | 2,222,512 | $3.69M | 0.00% | −46,154−2.0% | Reduced |
| UBS Group AG | 2,417,053 | $4.01M | 0.00% | −2,405,794−49.9% | Reduced |
| JPMorgan Chase & Co | 2,501,332 | $4.15M | 0.00% | +926,361+58.8% | Added |
| Charles Schwab Investment Management Inc | 2,741,986 | $4.55M | 0.00% | −755,420−21.6% | Reduced |
| Northern Trust Corp | 3,529,392 | $5.86M | 0.00% | −168,382−4.6% | Reduced |
| Lazard Asset Management LLC | 3,609,314 | $5.99M | 0.01% | +1,060,647+41.6% | Added |
| Goldman Sachs Group Inc | 4,001,214 | $6.64M | 0.00% | +161,394+4.2% | Added |
| Morgan Stanley | 4,108,488 | $6.82M | 0.00% | +940,546+29.7% | Added |
| Bank of America Corp | 4,158,882 | $6.90M | 0.00% | +3,577,300+615.1% | Added |
| D. E. Shaw & Co., Inc. | 4,731,688 | $7.85M | 0.01% | +4,731,688 | New |
| Marshall Wace, LLP | 4,896,428 | $8.13M | 0.01% | +3,974,941+431.4% | Added |
| Millennium Management LLC | 6,386,911 | $10.6M | 0.01% | +1,798,385+39.2% | Added |
| Deerfield Management Company, L.P. (Series C) | 6,906,362 | $11.5M | 0.23% | +6,906,362 | New |
| State Street Corp | 8,139,496 | $13.5M | 0.00% | −935,402−10.3% | Reduced |
| Geode Capital Management, LLC | 8,428,840 | $14.0M | 0.00% | +43,622+0.5% | Added |
| Weiss Asset Management LP | 11,192,800 | $18.6M | 0.50% | +11,192,800 | New |
| Sculptor Capital LP | 12,717,400 | $21.1M | 0.47% | +12,717,400 | New |
| BlackRock, Inc. | 27,604,974 | $45.8M | 0.00% | −563,638−2.0% | Reduced |
| Vanguard Group Inc | 29,500,071 | $49.0M | 0.00% | +293,740+1.0% | Added |
| Rubric Capital Management LP | 48,706,640 | $80.9M | 1.45% | 00.0% | Unchanged |
| Washington Growth Strategies LLC | 2 | – | – | +2 | New |
| Intrinsic Edge Capital Management LLC | 0 | $0 | 0.00% | −1,100,000−100.0% | Sold out |
| Skaana Management L.P. | 0 | $0 | 0.00% | −478,614−100.0% | Sold out |
| Essential Planning, LLC. | 0 | $0 | 0.00% | −331,175−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −145,977−100.0% | Sold out |
| Whitefort Capital Management, LP | 0 | $0 | 0.00% | −134,490−100.0% | Sold out |
| Wolverine Trading, LLC | 0 | $0 | 0.00% | −97,722−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −69,591−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −66,282−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −61,600−100.0% | Sold out |
| Zacks Investment Management | 0 | $0 | 0.00% | −33,300−100.0% | Sold out |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Granite Investment Partners, LLC | 0 | $0 | 0.00% | −14,356−100.0% | Sold out |
| GTS Securities LLC | 0 | $0 | 0.00% | −12,944−100.0% | Sold out |
| Mill Creek Capital Advisors, LLC | 0 | $0 | 0.00% | −12,383−100.0% | Sold out |
| Public Employees Retirement System of Ohio | 0 | $0 | 0.00% | −11,055−100.0% | Sold out |
| Pathstone Holdings, LLC | 0 | $0 | 0.00% | −10,541−100.0% | Sold out |
| McAdam, LLC | 0 | $0 | 0.00% | −10,054−100.0% | Sold out |
| GeoWealth Management, LLC | 0 | $0 | 0.00% | −1,215−100.0% | Sold out |
| Signaturefd, LLC | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Fifth Third Bancorp | 0 | $0 | 0.00% | −550−100.0% | Sold out |
| Sugar Maple Asset Management, LLC | 0 | $0 | 0.00% | −350−100.0% | Sold out |
| Newbridge Financial Services Group, Inc. | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Cornerstone Planning Group LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Nuveen Asset Management, LLC | – | – | – | – | Not filed |