Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Opko Health, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 255
- +21 vs. Q4 2024
- Shares held
- 242.1M
- +46.0M (+23.4%) vs. Q4 2024
- Total value
- $401.4M
- +$113.2M (+39.3%) vs. Q4 2024
- New holders
- 44
- 76 more added
- Sold out
- 23
- 57 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| PBMares Wealth Management LLC | 27,021 | $44.9K | 0.01% | 00.0% | Unchanged |
| Voleon Capital Management LP | 27,225 | $45.2K | 0.00% | +27,225 | New |
| Creative Planning | 28,097 | $46.6K | 0.00% | +3,833+15.8% | Added |
| Point72 (DIFC) Ltd | 28,907 | $48.0K | 0.00% | +6,162+27.1% | Added |
| Equitable Holdings, Inc. | 28,931 | $48.0K | 0.00% | +10.0% | Added |
| EP Wealth Advisors, LLC | 29,238 | $48.5K | 0.00% | +338+1.2% | Added |
| Capital Advisors Inc | 350,000 | $48.8K | 0.00% | +200,000+133.3% | Added |
| State of Wisconsin Investment Board | 29,770 | $49.4K | 0.00% | −4,106−12.1% | Reduced |
| CIBC World Markets Inc. | 29,928 | $49.7K | 0.00% | 00.0% | Unchanged |
| Brinker Capital Investments, LLC | 30,000 | $49.8K | 0.00% | 00.0% | Unchanged |
| IPG Investment Advisors LLC | 30,000 | $49.8K | 0.01% | 00.0% | Unchanged |
| Orion Portfolio Solutions, LLC | 30,000 | $49.8K | 0.00% | 00.0% | Unchanged |
| Brighton Jones LLC | 30,141 | $50.0K | 0.00% | +141+0.5% | Added |
| Ameritas Investment Partners, Inc. | 31,889 | $52.9K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 31,900 | $53.0K | 0.00% | 00.0% | Unchanged |
| Operose Advisors LLC | 32,000 | $53.1K | 0.02% | 00.0% | Unchanged |
| Norris Perne & French LLP | 32,000 | $53.1K | 0.00% | +2,000+6.7% | Added |
| RSM US Wealth Management LLC | 33,757 | $56.0K | 0.00% | −3,329−9.0% | Reduced |
| Victory Capital Management Inc | 36,616 | $60.8K | 0.00% | −1,711−4.5% | Reduced |
| HSBC Holdings PLC | 36,852 | $61.0K | 0.00% | −1,034−2.7% | Reduced |
| HighTower Advisors, LLC | 38,906 | $64.6K | 0.00% | −1,085−2.7% | Reduced |
| RK Asset Management, LLC | 40,485 | $67.0K | 0.06% | +4,000+11.0% | Added |
| Pensionmark Financial Group, LLC | 40,618 | $67.4K | 0.00% | 00.0% | Unchanged |
| Atom Investors LP | 40,760 | $67.7K | 0.01% | +7,993+24.4% | Added |
| Shell Asset Management Co | 40,997 | $68.0K | 0.00% | +600+1.5% | Added |
| Tower Research Capital LLC (TRC) | 42,450 | $70.0K | 0.00% | +24,627+138.2% | Added |
| Aquatic Capital Management LLC | 45,966 | $76.3K | 0.00% | +45,966 | New |
| Humankind Investments LLC | 46,413 | $77.0K | 0.02% | −1,208−2.5% | Reduced |
| Inspire Advisors, LLC | 47,130 | $78.2K | 0.01% | +47,130 | New |
| Captrust Financial Advisors | 48,482 | $80.5K | 0.00% | +10,952+29.2% | Added |
| Jump Financial, LLC | 49,070 | $81.5K | 0.00% | +49,070 | New |
| Farmers National Bank | 50,300 | $83.5K | 0.02% | 00.0% | Unchanged |
| Kestra Advisory Services, LLC | 50,307 | $83.5K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 50,794 | $84.3K | 0.00% | −596,291−92.2% | Reduced |
| Transcend Wealth Collective, LLC | 50,850 | $84.4K | 0.01% | 00.0% | Unchanged |
| First Manhattan Co | 51,750 | $85.9K | 0.00% | 00.0% | Unchanged |
| Headlands Technologies LLC | 52,149 | $86.6K | 0.01% | +52,149 | New |
| Great West Life Assurance Co | 54,068 | $90.0K | 0.00% | 00.0% | Unchanged |
| Mercer Global Advisors Inc | 54,957 | $91.2K | 0.00% | +11,790+27.3% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 55,140 | $91.5K | 0.00% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 55,301 | $91.8K | 0.00% | +20,000+56.7% | Added |
| The PNC Financial Services Group, Inc. | 56,800 | $94.3K | 0.00% | 00.0% | Unchanged |
| Kestra Private Wealth Services, LLC | 58,450 | $97.0K | 0.00% | −1,250−2.1% | Reduced |
| Cetera Investment Advisers | 60,556 | $100.5K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 60,801 | $100.9K | 0.00% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 61,502 | $102.0K | 0.00% | 00.0% | Unchanged |
| Pictet Asset Management Holding SA | 65,495 | $108.7K | 0.00% | 00.0% | Unchanged |
| Cascade Financial Partners, LLC | 66,490 | $110.4K | 0.01% | 00.0% | Unchanged |
| ProShare Advisors LLC | 69,045 | $114.6K | 0.00% | −22,685−24.7% | Reduced |
| CIBC World Markets Corp | 70,769 | $117.5K | 0.00% | +40,287+132.2% | Added |
| KLP Kapitalforvaltning AS | 74,000 | $122.8K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 74,503 | $124.0K | 0.00% | +67,487+961.9% | Added |
| Wealth Enhancement Advisory Services, LLC | 74,706 | $124.0K | 0.00% | +45,798+158.4% | Added |
| Two Sigma Securities, LLC | 75,647 | $125.6K | 0.02% | −135−0.2% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 77,449 | $128.6K | 0.00% | 00.0% | Unchanged |
| Quadrature Capital Ltd | 77,658 | $128.9K | 0.00% | +77,658 | New |
| Caxton Associates LLP | 78,128 | $129.7K | 0.00% | +78,128 | New |
| 360 Financial, Inc. | 79,300 | $131.6K | 0.05% | −1,500−1.9% | Reduced |
| Teacher Retirement System of Texas | 83,766 | $139.1K | 0.00% | +83,766 | New |
| Balyasny Asset Management LLC | 84,196 | $139.8K | 0.00% | +73,432+682.2% | Added |
| Raymond James Financial Inc | 85,370 | $141.7K | 0.00% | −65,300−43.3% | Reduced |
| Hollencrest Capital Management | 90,000 | $149.4K | 0.01% | 00.0% | Unchanged |
| American Century Companies Inc | 92,785 | $154.0K | 0.00% | +92,785 | New |
| Ameriprise Financial Inc | 94,091 | $156.2K | 0.00% | −300−0.3% | Reduced |
| Arizona State Retirement System | 97,883 | $162.5K | 0.00% | −3,005−3.0% | Reduced |
| Intrepid Capital Management Inc | 100,000 | $166.0K | 0.08% | 00.0% | Unchanged |
| Csenge Advisory Group | 117,000 | $166.1K | 0.01% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 103,110 | $171.0K | 0.00% | 00.0% | Unchanged |
| Phoenix Holdings Ltd. | 100,000 | $171.3K | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 112,000 | $185.9K | 0.00% | +5,631+5.3% | Added |
| Van Eck Associates Corp | 113,506 | $188.0K | 0.00% | +6,722+6.3% | Added |
| Highline Wealth Partners LLC | 116,680 | $193.7K | 0.07% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 119,223 | $197.9K | 0.00% | +114,396+2,369.9% | Added |
| Manufacturers Life Insurance Company, The | 124,731 | $207.1K | 0.00% | −6,050−4.6% | Reduced |
| Numerai GP LLC | 133,187 | $221.1K | 0.04% | −6,568−4.7% | Reduced |
| Teton Advisors, Inc. | 144,500 | $239.9K | 0.15% | −5,500−3.7% | Reduced |
| Corebridge Financial, Inc. | 156,247 | $259.4K | 0.00% | −5,687−3.5% | Reduced |
| MetLife Investment Management | 164,230 | $272.6K | 0.00% | −37,935−18.8% | Reduced |
| Gabelli Funds LLC | 170,000 | $282.2K | 0.00% | 00.0% | Unchanged |
| Gamco Investors, Inc. Et Al | 175,000 | $290.5K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 176,260 | $292.6K | 0.00% | 00.0% | Unchanged |
| Capula Management Ltd | 182,512 | $303.0K | 0.00% | +182,512 | New |
| Ieq Capital, LLC | 183,363 | $304.4K | 0.00% | +147,944+417.7% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 189,194 | $314.1K | 0.00% | +2,411+1.3% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 201,345 | $334.2K | 0.00% | +179,045+802.9% | Added |
| Intech Investment Management LLC | 204,317 | $339.2K | 0.00% | +2,839+1.4% | Added |
| Zazove Associates LLC | 207,600 | $344.6K | 0.03% | +202,700+4,136.7% | Added |
| ExodusPoint Capital Management, LP | 209,300 | $347.0K | 0.00% | +35,600+20.5% | Added |
| Quantbot Technologies LP | 210,079 | $348.7K | 0.01% | +210,079 | New |
| Janus Henderson Group PLC | 206,314 | $351.8K | 0.00% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 216,357 | $359.2K | 0.01% | −198,096−47.8% | Reduced |
| Wells Fargo & Company | 230,015 | $381.8K | 0.00% | +753+0.3% | Added |
| Royal Bank of Canada | 236,609 | $393.0K | 0.00% | −5,319−2.2% | Reduced |
| Tudor Investment Corp Et Al | 244,821 | $406.4K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 263,901 | $438.1K | 0.00% | −6,213−2.3% | Reduced |
| Deutsche Bank AG | 281,647 | $467.5K | 0.00% | −28,220−9.1% | Reduced |
| Squarepoint Ops LLC | 301,861 | $501.1K | 0.00% | +166,523+123.0% | Added |
| XTX Topco Ltd | 309,290 | $513.4K | 0.03% | +114,486+58.8% | Added |
| Verition Fund Management LLC | 317,946 | $527.8K | 0.00% | +317,946 | New |
| California State Teachers Retirement System | 324,117 | $538.0K | 0.00% | 00.0% | Unchanged |