Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Opko Health, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 221
- 0 vs. Q3 2022
- Shares held
- 179.9M
- −5.08M (−2.7%) vs. Q3 2022
- Total value
- $224.8M
- −$124.8M (−35.7%) vs. Q3 2022
- New holders
- 33
- 64 more added
- Sold out
- 33
- 60 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Numerai GP LLC | 1,890,727 | $2.36M | 1.61% | +1,890,727 | New |
| Citigroup Inc | 2,132,483 | $2.67M | 0.00% | −9,909−0.5% | Reduced |
| Two Sigma Advisers, LP | 2,262,997 | $2.83M | 0.01% | +140,600+6.6% | Added |
| Two Sigma Investments, LP | 2,269,016 | $2.84M | 0.01% | −618,353−21.4% | Reduced |
| Renaissance Technologies LLC | 2,286,543 | $2.86M | 0.00% | −549,800−19.4% | Reduced |
| Deutsche Bank AG | 2,320,513 | $2.90M | 0.00% | +40,332+1.8% | Added |
| Nuveen Asset Management, LLC | 2,441,064 | $3.05M | 0.00% | +239,428+10.9% | Added |
| Oracle Investment Management Inc | 3,230,288 | $4.04M | 3.51% | −1,872,468−36.7% | Reduced |
| Norges Bank | 3,233,385 | $4.04M | 0.00% | 00.0% | Unchanged |
| Millennium Management LLC | 3,720,447 | $4.65M | 0.01% | +1,578,263+73.7% | Added |
| Goldman Sachs Group Inc | 3,785,796 | $4.73M | 0.00% | +979,242+34.9% | Added |
| Northern Trust Corp | 3,853,292 | $4.82M | 0.00% | −52,062−1.3% | Reduced |
| Charles Schwab Investment Management Inc | 4,374,623 | $5.47M | 0.00% | +561,093+14.7% | Added |
| D. E. Shaw & Co., Inc. | 5,786,177 | $7.23M | 0.01% | −182,129−3.1% | Reduced |
| Geode Capital Management, LLC | 7,987,366 | $9.98M | 0.00% | +158,178+2.0% | Added |
| Dimensional Fund Advisors LP | 8,956,810 | $11.2M | 0.00% | −1,866,831−17.2% | Reduced |
| State Street Corp | 10,445,318 | $13.1M | 0.00% | +71,045+0.7% | Added |
| BlackRock Inc. | 35,476,921 | $44.3M | 0.00% | +968,918+2.8% | Added |
| Vanguard Group Inc | 41,120,494 | $51.4M | 0.00% | +835,721+2.1% | Added |
| IFP Advisors, Inc | 400 | – | – | 00.0% | Unchanged |
| Sofos Investments, Inc. | 1 | – | – | +1 | New |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −835,828−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −477,599−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −445,083−100.0% | Sold out |
| First Trust Advisors LP | 0 | $0 | 0.00% | −190,553−100.0% | Sold out |
| Altshuler Shaham Ltd | 0 | $0 | 0.00% | −62,428−100.0% | Sold out |
| Ergoteles LLC | 0 | $0 | 0.00% | −97,530−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −91,634−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −80,000−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −71,440−100.0% | Sold out |
| Virginia Retirement Systems Et Al | 0 | $0 | 0.00% | −50,900−100.0% | Sold out |
| Lehman & Derafelo Financial Resources LLC | 0 | $0 | 0.00% | −45,700−100.0% | Sold out |
| Captrust Financial Advisors | 0 | $0 | 0.00% | −38,907−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −38,744−100.0% | Sold out |
| Kestra Private Wealth Services, LLC | 0 | $0 | 0.00% | −34,900−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −21,328−100.0% | Sold out |
| North Star Investment Management Corp. | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Susquehanna International Group Ltd. | 0 | $0 | 0.00% | −19,090−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −15,428−100.0% | Sold out |
| Capital Square, LLC | 0 | $0 | 0.00% | −14,000−100.0% | Sold out |
| Toroso Investments, LLC | 0 | $0 | 0.00% | −10,400−100.0% | Sold out |
| Eqis Capital Management, Inc. | 0 | $0 | 0.00% | −10,283−100.0% | Sold out |
| Gabelli & Co Investment Advisers, Inc. | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −6,953−100.0% | Sold out |
| Leonteq Securities AG | 0 | $0 | 0.00% | −4,000−100.0% | Sold out |
| Cutler Group LP | 0 | $0 | 0.00% | −3,411−100.0% | Sold out |
| JJJ Advisors Inc. | 0 | $0 | 0.00% | −3,200−100.0% | Sold out |
| JFS Wealth Advisors, LLC | 0 | $0 | 0.00% | −273−100.0% | Sold out |
| Ronald Blue Trust, Inc. | 0 | $0 | 0.00% | −427−100.0% | Sold out |
| TCI Wealth Advisors, Inc. | 0 | $0 | 0.00% | −39−100.0% | Sold out |
| Focused Wealth Management, Inc | 0 | $0 | 0.00% | −50−100.0% | Sold out |
| Hoey Investments, Inc | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Disciplined Investments, LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| SJS Investment Consulting Inc. | 0 | $0 | 0.00% | −91−100.0% | Sold out |