Skip to main content

Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Opko Health, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
236
+30 vs. Q3 2021
Shares held
190.2M
+6.95M (+3.8%) vs. Q3 2021
Total value
$914.8M
+$246.0M (+36.8%) vs. Q3 2021
New holders
53
58 more added
Sold out
23
63 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 236 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ4 2021: $914.8M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2021.

Institutions holding OPK in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
CIBC Asset Management Inc32,472$156.0K0.00%+4,283+15.2%Added
STRS Ohio33,900$163.0K0.00%00.0%Unchanged
Pictet Asset Management SA34,600$166.0K0.00%00.0%Unchanged
Cim Investment Mangement Inc36,486$175.0K0.05%00.0%Unchanged
RK Asset Management, LLC36,685$176.0K0.16%+36,685New
Mackenzie Financial Corp37,721$181.0K0.00%−3,982−9.5%Reduced
Engineers Gate Manager LP39,395$189.0K0.01%−44,776−53.2%Reduced
Gotham Asset Management, LLC39,488$190.0K0.01%+11,823+42.7%Added
HighTower Advisors, LLC40,355$195.0K0.00%+2,566+6.8%Added
Walleye Trading LLC40,680$196.0K0.00%+40,680New
Kestra Advisory Services, LLC41,336$199.0K0.00%+11,260+37.4%Added
Captrust Financial Advisors42,468$204.0K0.00%+10,209+31.6%Added
Algert Global LLC42,820$206.0K0.03%00.0%Unchanged
360 Financial, Inc.42,760$206.0K0.09%+8,300+24.1%Added
Tower Research Capital LLC (TRC)44,306$213.0K0.00%−41,869−48.6%Reduced
Envestnet Asset Management Inc45,356$218.0K0.00%+45,356New
Benchmark Financial Wealth Advisors, LLC48,502$233.0K0.10%00.0%Unchanged
Farmers National Bank50,300$241.9K0.08%−7,200−12.5%Reduced
Amalgamated Bank51,797$249.0K0.00%−97−0.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)55,140$265.0K0.00%+10,074+22.4%Added
RPg Family Wealth Advisory, LLC55,330$266.1K0.11%00.0%Unchanged
Cornerstone Investment Partners, LLC55,500$267.0K0.01%+55,500New
Shell Asset Management Co56,778$273.0K0.01%+268+0.5%Added
DuPont Capital Management Corp57,455$276.0K0.01%−22,908−28.5%Reduced
Graham Capital Management, L.P.57,398$276.0K0.02%+57,398New
Raymond James Financial Services Advisors, Inc.58,221$280.0K0.00%+161+0.3%Added
Occudo Quantitative Strategies LP58,901$283.0K0.03%−77,001−56.7%Reduced
HSBC Holdings PLC58,734$286.0K0.00%+3,312+6.0%Added
Public Employees Retirement Association of Colorado61,502$296.0K0.00%00.0%Unchanged
Gsa Capital Partners LLP65,604$316.0K0.04%+65,604New
Raymond James & Associates66,982$322.0K0.00%−13,004−16.3%Reduced
Norris Perne & French LLP67,000$322.0K0.02%00.0%Unchanged
BDO Wealth Advisors, LLC67,000$322.0K0.03%+6,000+9.8%Added
Landscape Capital Management, L.L.C.68,023$327.0K0.05%−700,784−91.2%Reduced
Sowell Financial Services LLC75,200$362.0K0.02%+5,600+8.0%Added
Bank of Nova Scotia77,477$376.0K0.00%+77,477New
Fairfield, Bush & Co.79,650$383.0K0.18%+15,000+23.2%Added
Hollencrest Capital Management83,980$404.0K0.03%+50,000+147.1%Added
Sequoia Financial Advisors, LLC84,071$404.0K0.01%+84,071New
Sax Wealth Advisors, LLC84,110$405.0K0.08%−25,491−23.3%Reduced
Creative Planning85,545$411.0K0.00%−122−0.1%Reduced
Teacher Retirement System of Texas86,522$416.0K0.00%+16,288+23.2%Added
ProShare Advisors LLC87,297$420.0K0.00%+36,089+70.5%Added
Janus Henderson Group PLC88,077$424.0K0.00%+44,259+101.0%Added
Jump Financial, LLC93,080$447.0K0.03%−274,235−74.7%Reduced
AE Wealth Management LLC102,073$491.0K0.00%−20,275−16.6%Reduced
Metropolitan Life Insurance Co105,379$506.9K0.01%−2,402−2.2%Reduced
Matrix Private Capital Group LLC106,086$510.0K0.24%00.0%Unchanged
Virginia Retirement Systems Et Al118,800$571.0K0.01%−25,900−17.9%Reduced
Arizona State Retirement System119,166$573.0K0.00%+512+0.4%Added
MetLife Investment Management120,947$581.8K0.00%−19,559−13.9%Reduced
Handelsbanken Fonder AB123,621$595.0K0.00%+44,200+55.7%Added
SG Americas Securities, LLC135,741$653.0K0.00%−124,006−47.7%Reduced
Wolverine Asset Management LLC138,500$666.0K0.01%+138,500New
Ameriprise Financial Inc141,039$679.0K0.00%−4,190−2.9%Reduced
AQR Capital Management LLC154,259$742.0K0.00%−146,248−48.7%Reduced
Voya Investment Management LLC156,761$754.0K0.00%−1,726−1.1%Reduced
Capital Advisors Inc164,625$792.0K0.02%00.0%Unchanged
BNP Paribas Arbitrage, SA165,928$798.1K0.00%+26,707+19.2%Added
Simplex Trading, LLC196,852$946.0K0.03%+196,852New
Gamco Investors, Inc. Et Al200,000$962.0K0.01%00.0%Unchanged
Manufacturers Life Insurance Company, The208,471$1.00M0.00%−4,107−1.9%Reduced
Squarepoint Ops LLC210,703$1.01M0.00%+210,703New
American International Group, Inc.212,350$1.02M0.01%−6,353−2.9%Reduced
Teton Advisors, Inc.220,000$1.06M0.15%00.0%Unchanged
Gabelli Funds LLC221,000$1.06M0.01%00.0%Unchanged
Parametric Portfolio Associates LLC236,331$1.14M0.00%−37,190−13.6%Reduced
X-Square Capital, LLC250,965$1.21M0.61%+19,500+8.4%Added
New York State Common Retirement Fund265,546$1.28M0.00%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.267,989$1.29M0.01%−19,085−6.6%Reduced
Two Sigma Advisers, LP281,300$1.35M0.00%+261,000+1,285.7%Added
Price T Rowe Associates Inc284,674$1.37M0.00%00.0%Unchanged
Royal Bank of Canada291,805$1.40M0.00%+147,106+101.7%Added
Intrinsic Edge Capital Management LLC300,000$1.44M0.11%+300,000New
ETF Managers Group, LLC299,741$1.45M0.03%+51,025+20.5%Added
State Board of Administration of Florida Retirement System302,797$1.46M0.00%+126,777+72.0%Added
Cubist Systematic Strategies, LLC309,357$1.49M0.01%+214,532+226.2%Added
HRT Financial LP313,544$1.51M0.01%+313,544New
Deutsche Bank AG325,095$1.56M0.00%−6,874−2.1%Reduced
Legal & General Group Plc343,539$1.65M0.00%−3,833−1.1%Reduced
Zebra Capital Management LLC351,745$1.69M2.71%−117,338−25.0%Reduced
Susquehanna Fundamental Investments, LLC356,280$1.71M0.04%+177,840+99.7%Added
Group One Trading, L.P.360,111$1.73M0.03%−14,059−3.8%Reduced
Verition Fund Management LLC375,702$1.81M0.02%+375,702New
Victory Capital Management Inc375,949$1.81M0.00%−323,907−46.3%Reduced
Commonwealth Equity Services, LLC403,815$1.94M0.00%−100.0%Reduced
Old Mission Capital LLC412,551$1.98M0.10%+412,551New
Toronto Dominion Bank437,732$2.10M0.00%+437,732New
Invesco Ltd.440,515$2.12M0.00%−2,199,365−83.3%Reduced
Allspring Global Investments Holdings, LLC450,273$2.17M0.00%+450,273New
Credit Suisse AG459,278$2.21M0.00%+37,855+9.0%Added
UBS Asset Management Americas Inc460,219$2.21M0.00%+29,127+6.8%Added
Millennium Management LLC479,760$2.31M0.00%00.0%Unchanged
Principal Financial Group Inc488,075$2.35M0.00%−506,797−50.9%Reduced
First Trust Advisors LP494,098$2.38M0.00%−480,834−49.3%Reduced
Barclays PLC505,013$2.43M0.00%+286,073+130.7%Added
Balyasny Asset Management LLC508,967$2.45M0.01%+508,967New
State of Wisconsin Investment Board535,300$2.58M0.00%00.0%Unchanged
Advisor Group Holdings, Inc.552,413$2.66M0.01%+355,163+180.1%Added
California State Teachers Retirement System592,393$2.85M0.00%+19,485+3.4%Added