Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Fulcrum Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 172
- +43 vs. Q3 2025
- Shares held
- 67.4M
- +13.7M (+25.4%) vs. Q3 2025
- Total value
- $762.7M
- +$267.8M (+54.1%) vs. Q3 2025
- New holders
- 59
- 43 more added
- Sold out
- 16
- 49 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Essential Partners LLC | 1 | $11 | 0.00% | 00.0% | Unchanged |
| SJS Investment Consulting Inc. | 3 | $34 | 0.00% | +3 | New |
| SBI Securities Co., Ltd. | 4 | $45 | 0.00% | −24−85.7% | Reduced |
| Rothschild Investment LLC | 8 | $90 | 0.00% | +8 | New |
| MAI Capital Management | 10 | $114 | 0.00% | +10 | New |
| True Wealth Design, LLC | 16 | $181 | 0.00% | 00.0% | Unchanged |
| Keating Financial Advisory Services, Inc. | 24 | $271 | 0.00% | +24 | New |
| GAMMA Investing LLC | 25 | $283 | 0.00% | +25 | New |
| Caitong International Asset Management Co., Ltd | 41 | $464 | 0.00% | +41 | New |
| Signaturefd, LLC | 68 | $769 | 0.00% | +68 | New |
| Advisor Group Holdings, Inc. | 90 | $1.02K | 0.00% | 00.0% | Unchanged |
| Altshuler Shaham Ltd | 100 | $1.13K | 0.00% | +100 | New |
| Rialto Wealth Management, LLC | 159 | $1.80K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 180 | $2.00K | 0.00% | +180 | New |
| SRS Capital Advisors, Inc. | 181 | $2.05K | 0.00% | +181 | New |
| EverSource Wealth Advisors, LLC | 207 | $2.34K | 0.00% | +3+1.5% | Added |
| Rockefeller Capital Management L.P. | 224 | $2.53K | 0.00% | +224 | New |
| UMA Financial Services, Inc. | 283 | $3.20K | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 287 | $3.25K | 0.00% | +287 | New |
| Optiver Holding B.V. | 322 | $3.64K | 0.00% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 328 | $3.71K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 372 | $4.00K | 0.00% | +173+86.9% | Added |
| National Bank of Canada | 443 | $5.00K | 0.00% | +15+3.5% | Added |
| Northwestern Mutual Wealth Management Co | 472 | $5.34K | 0.00% | +472 | New |
| Aster Capital Management (DIFC) Ltd | 623 | $7.05K | 0.00% | +623 | New |
| Los Angeles Capital Management LLC | 915 | $7.87K | 0.00% | +915 | New |
| UBS Asset Management Americas Inc | 709 | $8.02K | 0.00% | +709 | New |
| IFP Advisors, Inc | 988 | $11.2K | 0.00% | −988−50.0% | Reduced |
| GF Fund Management Co. Ltd. | 1,062 | $12.0K | 0.00% | +1,062 | New |
| Amalgamated Bank | 1,353 | $15.0K | 0.00% | −794−37.0% | Reduced |
| The PNC Financial Services Group, Inc. | 1,442 | $16.3K | 0.00% | +25+1.8% | Added |
| Tower Research Capital LLC (TRC) | 1,624 | $18.4K | 0.00% | −286−15.0% | Reduced |
| Versant Capital Management, Inc | 1,800 | $20.4K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 2,190 | $24.8K | 0.00% | −4,922−69.2% | Reduced |
| Sterling Capital Management LLC | 2,332 | $26.4K | 0.00% | −414−15.1% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,630 | $29.7K | 0.00% | +2,630 | New |
| California State Teachers Retirement System | 2,651 | $30.0K | 0.00% | −683−20.5% | Reduced |
| Meeder Asset Management Inc | 3,479 | $39.3K | 0.00% | +3,479 | New |
| Russell Investments Group, Ltd. | 3,574 | $40.4K | 0.00% | −10,157−74.0% | Reduced |
| Ameritas Investment Partners, Inc. | 3,598 | $40.7K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 3,602 | $40.7K | 0.00% | −679−15.9% | Reduced |
| Royal Bank of Canada | 4,107 | $47.0K | 0.00% | −996,742−99.6% | Reduced |
| Persistent Asset Partners Ltd | 6,615 | $74.8K | 0.04% | +6,615 | New |
| FMR LLC | 7,691 | $87.0K | 0.00% | +341+4.6% | Added |
| Simplex Trading, LLC | 8,014 | $90.6K | 0.00% | −4,786−37.4% | Reduced |
| Assetmark, Inc | 8,184 | $92.6K | 0.00% | −1,427−14.8% | Reduced |
| China Universal Asset Management Co., Ltd. | 8,819 | $99.7K | 0.01% | +8,819 | New |
| Quest Partners LLC | 9,658 | $109.2K | 0.01% | −25,717−72.7% | Reduced |
| ProShare Advisors LLC | 10,259 | $116.0K | 0.00% | +10,259 | New |
| BNP Paribas Arbitrage, SA | 10,522 | $119.0K | 0.00% | −3,752−26.3% | Reduced |
| SG Americas Securities, LLC | 11,766 | $133.0K | 0.00% | +11,766 | New |
| Bailard, Inc. | 11,781 | $133.2K | 0.00% | −15,100−56.2% | Reduced |
| Entropy Technologies, LP | 11,996 | $135.7K | 0.01% | +11,996 | New |
| Police & Firemen's Retirement System of New Jersey | 12,843 | $145.3K | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 12,883 | $145.7K | 0.00% | −1,065−7.6% | Reduced |
| JustInvest LLC | 13,158 | $148.8K | 0.00% | −10−0.1% | Reduced |
| Matisse Capital | 13,460 | $152.2K | 0.07% | −5,170−27.8% | Reduced |
| Alphabet Inc. | 14,262 | $161.3K | 0.01% | 00.0% | Unchanged |
| Winton Group Ltd | 14,294 | $161.7K | 0.01% | −1,918−11.8% | Reduced |
| EntryPoint Capital, LLC | 15,076 | $170.5K | 0.07% | +15,076 | New |
| Man Group plc | 15,253 | $172.5K | 0.00% | +15,253 | New |
| Alliancebernstein L.P. | 15,270 | $172.7K | 0.00% | −59,320−79.5% | Reduced |
| AQR Capital Management LLC | 15,502 | $175.3K | 0.00% | +15,502 | New |
| Legal & General Group Plc | 16,373 | $185.2K | 0.00% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 16,791 | $189.9K | 0.00% | −349,512−95.4% | Reduced |
| Quarry LP | 17,165 | $194.1K | 0.03% | +13,391+354.8% | Added |
| Renaissance Technologies LLC | 17,400 | $196.8K | 0.00% | −230,800−93.0% | Reduced |
| Intech Investment Management LLC | 19,747 | $223.3K | 0.00% | +2,503+14.5% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 20,022 | $226.4K | 0.00% | +16+0.1% | Added |
| Virtus Investment Advisers, Inc. | 20,463 | $231.4K | 0.06% | +20,463 | New |
| JPMorgan Chase & Co | 20,789 | $235.1K | 0.00% | +2,720+15.1% | Added |
| Creative Planning | 22,104 | $250.0K | 0.00% | +7,750+54.0% | Added |
| MetLife Investment Management | 22,714 | $256.9K | 0.00% | −3,181−12.3% | Reduced |
| Fox Run Management, L.L.C. | 25,568 | $289.2K | 0.04% | −25,223−49.7% | Reduced |
| Prelude Capital Management, LLC | 28,832 | $326.1K | 0.02% | 00.0% | Unchanged |
| Quantinno Capital Management LP | 29,264 | $331.0K | 0.00% | +4,615+18.7% | Added |
| LMR Partners LLP | 30,000 | $339.3K | 0.00% | 00.0% | Unchanged |
| Country Trust Bank | 30,041 | $339.8K | 0.01% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 30,500 | $345.0K | 0.00% | −1,000−3.2% | Reduced |
| Woodline Partners LP | 30,793 | $348.3K | 0.00% | +30,793 | New |
| Axq Capital, LP | 31,545 | $356.8K | 0.08% | +31,545 | New |
| Group One Trading, L.P. | 34,750 | $393.0K | 0.01% | +28,990+503.3% | Added |
| Campbell & CO Investment Adviser LLC | 35,601 | $402.6K | 0.02% | −66,869−65.3% | Reduced |
| SEI Investments Co | 37,511 | $424.2K | 0.00% | +37,511 | New |
| Commonwealth Equity Services, LLC | 40,000 | $452.4K | 0.00% | −43,428−52.1% | Reduced |
| Jain Global LLC | 41,260 | $466.7K | 0.00% | +41,260 | New |
| HSBC Holdings PLC | 43,262 | $497.9K | 0.00% | −10,544−19.6% | Reduced |
| Franklin Resources Inc | 44,249 | $500.5K | 0.00% | −15,773−26.3% | Reduced |
| Graham Capital Management, L.P. | 48,464 | $548.1K | 0.02% | +17,978+59.0% | Added |
| STRS Ohio | 49,300 | $557.6K | 0.00% | −28,600−36.7% | Reduced |
| Brevan Howard Capital Management LP | 48,900 | $559.4K | 0.01% | +33,597+219.5% | Added |
| KVP Capital Advisors, LP | 50,000 | $565.5K | 0.58% | +50,000 | New |
| Burkehill Global Management, LP | 50,000 | $565.5K | 0.04% | +50,000 | New |
| Seven Grand Managers, LLC | 50,000 | $565.5K | 0.04% | +50,000 | New |
| XTX Topco Ltd | 51,802 | $585.9K | 0.02% | +51,802 | New |
| Millennium Management LLC | 54,431 | $615.6K | 0.00% | −96,436−63.9% | Reduced |
| DekaBank Deutsche Girozentrale | 60,000 | $617.0K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 55,713 | $630.1K | 0.00% | −13,659−19.7% | Reduced |
| New York State Common Retirement Fund | 57,725 | $652.9K | 0.00% | +44,625+340.6% | Added |
| Atom Investors LP | 60,595 | $685.3K | 0.05% | +60,595 | New |