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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
108
−1 vs. Q4 2021
Shares held
39.5M
+2.30M (+6.2%) vs. Q4 2021
Total value
$929.9M
+$273.2M (+41.6%) vs. Q4 2021
New holders
21
29 more added
Sold out
22
38 more reduced

1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 108 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ1 2022: $929.9M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2021.

Institutions holding FULC in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Adage Capital Partners GP, L.L.C.1,950,000$46.1M0.09%+230,000+13.4%Added
BlackRock Inc.2,228,610$52.7M0.00%+20,532+0.9%Added
TRV GP IV, LLC2,343,154$55.4M20.30%00.0%Unchanged
Suvretta Capital Management, LLC2,613,412$61.8M1.89%+237,841+10.0%Added
Cowen and Company, LLC3,453,371$81.7M8.23%+3,453,371New
RTW Investments, LP3,611,194$85.4M1.77%−255,678−6.6%Reduced
TRV GP III, LLC3,962,202$93.7M25.43%00.0%Unchanged
FMR LLC6,096,478$144.2M0.01%+14,161+0.2%Added
Holocene Advisors, LP0$00.00%−864,978−100.0%Sold out
Darwin Global Management, Ltd.0$00.00%−317,428−100.0%Sold out
HighVista Strategies LLC0$00.00%−89,963−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−75,525−100.0%Sold out
Millennium Management LLC0$00.00%−58,375−100.0%Sold out
HarbourVest Partners LLC0$00.00%−39,511−100.0%Sold out
Prudential Financial Inc0$00.00%−28,770−100.0%Sold out
UNC Management Company, Inc.0$00.00%−23,708−100.0%Sold out
Ergoteles LLC0$00.00%−21,400−100.0%Sold out
Alpine Global Management, LLC0$00.00%−20,905−100.0%Sold out
Old Mission Capital LLC0$00.00%−20,670−100.0%Sold out
Gyon Technologies Capital Management, LP0$00.00%−15,534−100.0%Sold out
AQR Capital Management LLC0$00.00%−14,024−100.0%Sold out
Marshall Wace, LLP0$00.00%−13,513−100.0%Sold out
Rafferty Asset Management, LLC0$00.00%−12,971−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−11,734−100.0%Sold out
Boulder Hill Capital Management LP0$00.00%−11,600−100.0%Sold out
Jump Financial, LLC0$00.00%−10,882−100.0%Sold out
Hershey Trust Co0$00.00%−7,903−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−982−100.0%Sold out
State of Wyoming0$00.00%−749−100.0%Sold out
Smith Group Asset Management, LLC0$00.00%−520−100.0%Sold out
AlphaCentric Advisors LLC––––Not filed