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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q3 2021

Institutional positions in Fulcrum Therapeutics, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
101
+35 vs. Q2 2021
Shares held
36.6M
+9.75M (+36.4%) vs. Q2 2021
Total value
$1.03B
+$750.7M (+267.3%) vs. Q2 2021
New holders
43
35 more added
Sold out
8
16 more reduced

1 institution that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 101 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ3 2021: $1.03B
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q2 2021.

Institutions holding FULC in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Ellevest, Inc.4$00.00%+4New
Federated Hermes, Inc.71$2.00K0.00%−587−89.2%Reduced
Daiwa Securities Group Inc.138$4.00K0.00%+86+165.4%Added
Advisor Group Holdings, Inc.300$8.00K0.00%+300New
Tower Research Capital LLC (TRC)534$15.0K0.00%−1,119−67.7%Reduced
Smith Group Asset Management, LLC520$15.0K0.00%+520New
Cutler Group LP900$25.0K0.00%+900New
Penserra Capital Management LLC925$26.0K0.00%+180+24.2%Added
UBS Group AG1,305$37.0K0.00%+363+38.5%Added
Ameritas Investment Partners, Inc.2,042$58.0K0.00%+942+85.6%Added
Legal & General Group Plc2,129$60.0K0.00%+364+20.6%Added
Royal Bank of Canada3,240$91.0K0.00%+1,722+113.4%Added
Blackstone Group Inc.4,758$134.0K0.00%+4,758New
Group One Trading, L.P.4,973$140.0K0.00%+4,973New
Wells Fargo & Company5,859$165.0K0.00%−2,073−26.1%Reduced
Nisa Investment Advisors, LLC5,950$168.0K0.00%+900+17.8%Added
Metropolitan Life Insurance Co7,229$203.9K0.00%+7,229New
Citigroup Inc7,315$206.0K0.00%+396+5.7%Added
Paradigm Financial Advisors, LLC7,375$208.0K0.05%+7,375New
Jacobs Levy Equity Management, Inc7,487$211.0K0.00%−6,302−45.7%Reduced
Bank of America Corp7,468$211.0K0.00%−2,809−27.3%Reduced
STRS Ohio7,800$220.0K0.00%+4,600+143.8%Added
Hershey Trust Co7,929$224.0K0.00%+7,929New
Bank Julius Baer & Co. Ltd, Zurich8,500$240.0K0.00%+8+0.1%Added
MetLife Investment Management9,555$269.5K0.00%+9,555New
Voya Investment Management LLC10,551$298.0K0.00%+10,551New
Bank of Montreal11,501$325.0K0.00%−12,600−52.3%Reduced
ProShare Advisors LLC12,023$339.0K0.00%+404+3.5%Added
PDT Partners, LLC13,523$381.0K0.03%−4,477−24.9%Reduced
State of Wisconsin Investment Board13,600$384.0K0.00%+13,600New
Manufacturers Life Insurance Company, The14,007$395.0K0.00%+14,007New
California State Teachers Retirement System14,396$406.0K0.00%−16,163−52.9%Reduced
American International Group, Inc.14,583$411.0K0.00%+2,172+17.5%Added
Mass General Brigham, Inc15,860$447.0K0.12%+15,860New
Alliancebernstein L.P.16,600$468.0K0.00%00.0%Unchanged
New York State Common Retirement Fund18,598$525.0K0.00%+6,188+49.9%Added
SG Americas Securities, LLC19,228$542.0K0.00%+19,228New
ClariVest Asset Management LLC19,700$556.0K0.02%+19,700New
Verition Fund Management LLC20,000$564.0K0.01%+20,000New
Brandywine Managers, LLC20,388$575.0K0.60%00.0%Unchanged
Panagora Asset Management Inc28,407$801.0K0.00%+27,579+3,330.8%Added
LMR Partners LLP30,000$846.0K0.01%+30,000New
Rhumbline Advisers30,199$852.0K0.00%+7,724+34.4%Added
Cubist Systematic Strategies, LLC30,498$860.0K0.01%+27,703+991.2%Added
Voloridge Investment Management, LLC30,533$861.0K0.01%+30,533New
Darwin Global Management, Ltd.33,997$959.0K0.18%+33,997New
Deutsche Bank AG36,595$1.03M0.00%+23,445+178.3%Added
Country Trust Bank37,341$1.05M0.03%00.0%Unchanged
Allianz Asset Management GmbH41,080$1.16M0.00%+41,080New
Tekla Capital Management LLC43,898$1.24M0.04%+43,898New
Price T Rowe Associates Inc44,400$1.25M0.00%+44,400New
Jane Street Group, LLC49,942$1.41M0.00%+49,942New
Ghost Tree Capital, LLC50,000$1.41M0.47%+50,000New
Dimensional Fund Advisors LP50,748$1.43M0.00%−24,835−32.9%Reduced
Sofinnova Investments, Inc.51,006$1.44M0.09%+51,006New
EAM Investors, LLC55,383$1.56M0.26%+55,383New
Susquehanna Fundamental Investments, LLC57,726$1.63M0.03%+57,726New
Goldman Sachs Group Inc62,502$1.76M0.00%+35,036+127.6%Added
Charles Schwab Investment Management Inc67,348$1.90M0.00%+13,064+24.1%Added
EAM Global Investors LLC78,384$2.21M0.52%+78,384New
Schonfeld Strategic Advisors LLC82,100$2.32M0.03%+82,100New
Morgan Stanley85,011$2.40M0.00%+12,715+17.6%Added
Bank of New York Mellon Corp95,031$2.68M0.00%+31,059+48.6%Added
Marshall Wace North America L.P.95,104$2.68M0.01%+95,104New
Millennium Management LLC99,707$2.81M0.00%−525,928−84.1%Reduced
Fiduciary Trust Co129,215$3.65M0.06%+3,216+2.6%Added
Renaissance Technologies LLC133,900$3.78M0.00%+133,900New
Point72 Asset Management, L.P.140,000$3.95M0.02%−412,885−74.7%Reduced
Two Sigma Advisers, LP142,200$4.01M0.01%+142,200New
Nuveen Asset Management, LLC131,878$4.07M0.00%+15,847+13.7%Added
Marshall Wace, LLP151,689$4.28M0.02%+151,689New
Platinum Investment Management Ltd152,186$4.29M0.12%00.0%Unchanged
JPMorgan Chase & Co173,727$4.90M0.00%−10,845−5.9%Reduced
Silverarc Capital Management, LLC185,691$5.24M3.03%+185,691New
Lord, Abbett & Co. LLC187,043$5.28M0.01%+187,043New
Natixis250,000$7.11M0.02%+250,000New
Alphabet Inc.255,452$7.21M0.17%−422,689−62.3%Reduced
Northern Trust Corp257,872$7.28M0.00%+40,161+18.4%Added
Perceptive Advisors LLC294,118$8.30M0.12%00.0%Unchanged
Bessemer Group Inc310,618$8.76M0.02%+24,904+8.7%Added
Citadel Advisors LLC313,910$8.86M0.01%−96,615−23.5%Reduced
Acuta Capital Partners, LLC322,500$9.10M3.24%−281,574−46.6%Reduced
Parkman Healthcare Partners LLC338,796$9.56M2.42%+192,407+131.4%Added
Harvard Management Co Inc410,714$11.6M0.68%00.0%Unchanged
State Street Corp452,312$12.8M0.00%+140,087+44.9%Added
Rock Springs Capital Management LP455,290$12.8M0.27%+455,290New
Geode Capital Management, LLC458,442$12.9M0.00%+101,850+28.6%Added
Invesco Ltd.596,057$16.8M0.00%+596,057New
Two Sigma Investments, LP632,539$17.8M0.05%+616,928+3,951.9%Added
Polar Capital Holdings Plc750,000$21.2M0.12%+750,000New
D. E. Shaw & Co., Inc.798,101$22.5M0.03%+798,101New
Adage Capital Partners GP, L.L.C.1,180,000$33.3M0.07%+1,180,000New
Boxer Capital, LLC1,250,000$35.3M1.23%+1,250,000New
Vanguard Group Inc1,253,426$35.4M0.00%+346,391+38.2%Added
Cowen and Company, LLC1,560,563$44.0M2.12%+240,676+18.2%Added
Suvretta Capital Management, LLC1,941,969$54.8M0.93%+314,525+19.3%Added
BlackRock Inc.2,030,873$57.3M0.00%+733,428+56.5%Added
TRV GP IV, LLC2,343,154$66.1M15.00%00.0%Unchanged
RTW Investments, LP3,855,291$108.8M1.64%+650,000+20.3%Added
TRV GP III, LLC4,962,202$140.0M26.57%−1,000,000−16.8%Reduced