Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Design Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 136
- +12 vs. Q1 2026
- Shares held
- 43.3M
- +5.32M (+14.0%) vs. Q1 2026
- Total value
- $626.4M
- +$222.3M (+55.0%) vs. Q1 2026
- New holders
- 28
- 61 more added
- Sold out
- 16
- 32 more reduced
1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| KVP Capital Advisors, LP | 185,000 | $2.68M | 1.96% | +185,000 | New |
| Eversept Partners, LP | 190,000 | $2.75M | 0.15% | +190,000 | New |
| D. E. Shaw & Co., Inc. | 195,645 | $2.83M | 0.00% | −274,625−58.4% | Reduced |
| Prudential Financial Inc | 224,170 | $3.24M | 0.00% | +178,360+389.3% | Added |
| Vanguard Fiduciary Trust Co | 230,202 | $3.33M | 0.00% | +34,544+17.7% | Added |
| Vanguard Portfolio Management LLC | 251,442 | $3.64M | 0.00% | +112,877+81.5% | Added |
| Charles Schwab Investment Management Inc | 271,264 | $3.93M | 0.00% | +29,779+12.3% | Added |
| Acuta Capital Partners, LLC | 282,564 | $4.09M | 2.85% | +136,664+93.7% | Added |
| Algert Global LLC | 296,085 | $4.28M | 0.05% | +91,346+44.6% | Added |
| Northern Trust Corp | 353,197 | $5.11M | 0.00% | +52,918+17.6% | Added |
| Kennedy Capital Management, Inc. | 384,036 | $5.56M | 0.10% | +112,482+41.4% | Added |
| Renaissance Technologies LLC | 387,913 | $5.61M | 0.01% | −20,287−5.0% | Reduced |
| Qube Research & Technologies Ltd | 437,079 | $6.32M | 0.01% | +402,896+1,178.6% | Added |
| Siren, L.L.C. | 523,212 | $7.57M | 0.15% | +523,212 | New |
| Acadian Asset Management LLC | 537,479 | $7.77M | 0.01% | −79,002−12.8% | Reduced |
| Jacobs Levy Equity Management, Inc | 565,597 | $8.18M | 0.03% | +276,212+95.4% | Added |
| Goldman Sachs Group Inc | 656,584 | $9.50M | 0.00% | +151,866+30.1% | Added |
| Dimensional Fund Advisors LP | 694,743 | $10.1M | 0.00% | +262,903+60.9% | Added |
| Woodline Partners LP | 700,354 | $10.1M | 0.03% | −261,147−27.2% | Reduced |
| State Street Corp | 736,221 | $10.7M | 0.00% | +76,646+11.6% | Added |
| Morgan Stanley | 765,425 | $11.1M | 0.00% | +108,860+16.6% | Added |
| FMR LLC | 776,462 | $11.2M | 0.00% | −21,949−2.7% | Reduced |
| Sofinnova Investments, Inc. | 865,135 | $12.5M | 0.67% | +865,135 | New |
| Geode Capital Management, LLC | 958,417 | $13.9M | 0.00% | +265,899+38.4% | Added |
| Almitas Capital LLC | 1,026,893 | $14.9M | 3.56% | −503,442−32.9% | Reduced |
| Caption Management, LLC | 1,118,098 | $16.2M | 0.57% | +1,031,390+1,189.5% | Added |
| Vanguard Capital Management LLC | 1,571,022 | $22.7M | 0.00% | +221,172+16.4% | Added |
| Vivo Capital, LLC | 1,612,903 | $23.3M | 2.13% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 1,809,854 | $26.2M | 0.57% | +1,809,854 | New |
| Trails Edge Capital Partners, LP | 2,001,282 | $29.0M | 4.60% | +1,149,269+134.9% | Added |
| Point72 Asset Management, L.P. | 2,366,453 | $34.2M | 0.05% | −356,301−13.1% | Reduced |
| BlackRock, Inc. | 2,660,024 | $38.5M | 0.00% | +526,260+24.7% | Added |
| Driehaus Capital Management LLC | 2,661,115 | $38.5M | 0.22% | +916,128+52.5% | Added |
| Baker Bros. Advisors LP | 2,678,430 | $38.8M | 0.19% | +92,452+3.6% | Added |
| Logos Global Management LP | 3,000,000 | $43.4M | 1.87% | +1,050,000+53.8% | Added |
| Sr One Capital Management, LP | 6,526,476 | $94.4M | 9.09% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 0 | $0 | 0.00% | −2,972,973−100.0% | Sold out |
| Kynam Capital Management, LP | 0 | $0 | 0.00% | −784,606−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −151,008−100.0% | Sold out |
| Lynx1 Capital Management LP | 0 | $0 | 0.00% | −119,516−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −103,902−100.0% | Sold out |
| EAM Investors, LLC | 0 | $0 | 0.00% | −78,949−100.0% | Sold out |
| Velan Capital Investment Management LP | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −16,090−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −15,294−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −14,749−100.0% | Sold out |
| Mariner, LLC | 0 | $0 | 0.00% | −13,066−100.0% | Sold out |
| Baader Bank INC | 0 | $0 | 0.00% | −12,792−100.0% | Sold out |
| Mirabella Financial Services LLP | 0 | $0 | 0.00% | −11,814−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Root Financial Partners, LLC | 0 | $0 | 0.00% | −38−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −8−100.0% | Sold out |
| CWM, LLC | – | – | – | – | Not filed |