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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Design Therapeutics, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
87
−10 vs. Q2 2023
Shares held
32.9M
−5.92M (−15.3%) vs. Q2 2023
Total value
$77.6M
−$166.8M (−68.3%) vs. Q2 2023
New holders
14
26 more added
Sold out
24
38 more reduced

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 87 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ3 2023: $77.6M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q2 2023.

Institutions holding DSGN in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Sr One Capital Management, LP6,526,476$15.4M7.89%00.0%Unchanged
Logos Global Management LP5,032,501$11.9M1.69%+2,235,000+79.9%Added
Citadel Advisors LLC2,700,553$6.37M0.01%−155,553−5.4%Reduced
RTW Investments, LP2,512,986$5.93M0.13%+949,955+60.8%Added
BlackRock Inc.2,403,915$5.67M0.00%−590,136−19.7%Reduced
Baker Bros. Advisors LP1,500,000$3.54M0.02%+1,000,000+200.0%Added
Tang Capital Management LLC1,350,000$3.19M0.45%+1,350,000New
Prosight Management, LP1,203,745$2.84M0.90%+1,203,745New
Soleus Capital Management, L.P.1,025,000$2.42M0.24%+1,025,000New
Vanguard Group Inc986,711$2.33M0.00%+3,437+0.3%Added
Millennium Management LLC829,480$1.96M0.00%+549,601+196.4%Added
Principal Financial Group Inc716,818$1.69M0.00%−11,403−1.6%Reduced
State Street Corp692,723$1.63M0.00%+106,688+18.2%Added
Geode Capital Management, LLC634,720$1.50M0.00%−2,125−0.3%Reduced
Rock Springs Capital Management LP460,391$1.09M0.03%00.0%Unchanged
Goldman Sachs Group Inc444,498$1.05M0.00%−2,918−0.7%Reduced
Walleye Capital LLC373,513$881.5K0.01%+362,375+3,253.5%Added
Morgan Stanley360,258$850.2K0.00%+169,490+88.8%Added
Northern Trust Corp323,259$762.9K0.00%−1,479−0.5%Reduced
Assenagon Asset Management S.A.248,047$585.4K0.00%−53,641−17.8%Reduced
Candriam Luxembourg S.C.A.225,000$531.0K0.00%+40,000+21.6%Added
Prescott Group Capital Management, L.L.C.180,000$425.0K0.09%+180,000New
Charles Schwab Investment Management Inc173,545$409.6K0.00%−55,261−24.2%Reduced
Renaissance Technologies LLC164,200$388.0K0.00%+69,092+72.6%Added
Nuveen Asset Management, LLC153,387$362.0K0.00%−1,152−0.7%Reduced
Bank of New York Mellon Corp120,792$285.1K0.00%−1,873−1.5%Reduced
Two Sigma Advisers, LP112,800$266.2K0.00%+33,800+42.8%Added
Occudo Quantitative Strategies LP100,722$237.7K0.03%+100,722New
Bridgeway Capital Management, LLC80,500$190.0K0.00%+80,500New
STRS Ohio72,800$171.0K0.00%+72,800New
Barclays PLC71,678$169.2K0.00%+55,858+353.1%Added
FMR LLC70,058$165.3K0.00%−567,712−89.0%Reduced
Two Sigma Investments, LP63,835$150.7K0.00%−51,947−44.9%Reduced
Marshall Wace, LLP60,542$142.9K0.00%−52,380−46.4%Reduced
JPMorgan Chase & Co56,342$133.0K0.00%+4,359+8.4%Added
Dimensional Fund Advisors LP54,115$127.8K0.00%−5,520−9.3%Reduced
Rhumbline Advisers52,476$123.8K0.00%+886+1.7%Added
Bank of America Corp48,735$115.0K0.00%−29,143−37.4%Reduced
Jump Financial, LLC46,700$110.2K0.00%+34,561+284.7%Added
Gsa Capital Partners LLP43,581$103.0K0.01%−194,619−81.7%Reduced
Squarepoint Ops LLC42,562$100.4K0.00%+972+2.3%Added
Alliancebernstein L.P.41,400$97.7K0.00%00.0%Unchanged
XTX Topco Ltd38,472$90.8K0.02%+27,673+256.3%Added
HSBC Holdings PLC36,490$85.6K0.00%+36,490New
Algert Global LLC35,620$84.1K0.00%+16,190+83.3%Added
PDT Partners, LLC33,682$79.5K0.01%−13,830−29.1%Reduced
Prelude Capital Management, LLC33,400$78.8K0.01%+33,400New
Jane Street Group, LLC29,383$69.3K0.00%−3,951−11.9%Reduced
Corton Capital Inc.27,134$64.0K0.03%+9,811+56.6%Added
Cubist Systematic Strategies, LLC26,937$63.6K0.00%−39,749−59.6%Reduced
Susquehanna International Group, LLP22,537$53.2K0.00%−34,257−60.3%Reduced
Graham Capital Management, L.P.21,850$51.6K0.00%+21,850New
SG Americas Securities, LLC19,907$47.0K0.00%+19,907New
Prudential Financial Inc18,415$43.5K0.00%−7,800−29.8%Reduced
Virtus ETF Advisers LLC18,313$43.2K0.03%−1,824−9.1%Reduced
UBS Group AG18,064$42.6K0.00%−6,098−25.2%Reduced
Tower Research Capital LLC (TRC)16,520$39.0K0.00%+11,220+211.7%Added
American International Group, Inc.16,355$38.6K0.00%+582+3.7%Added
Tudor Investment Corp Et Al16,299$38.5K0.00%−4,262−20.7%Reduced
Voya Investment Management LLC14,090$33.3K0.00%00.0%Unchanged
D. E. Shaw & Co., Inc.11,740$27.7K0.00%−123,540−91.3%Reduced
Wells Fargo & Company8,032$19.0K0.00%−4,431−35.6%Reduced
California State Teachers Retirement System7,231$17.1K0.00%−3,670−33.7%Reduced
Royal Bank of Canada5,501$13.0K0.00%+1,927+53.9%Added
Point72 Middle East FZE4,925$11.6K0.00%−4,160−45.8%Reduced
Quantbot Technologies LP3,905$9.22K0.00%−800−17.0%Reduced
Amalgamated Bank3,280$8.00K0.00%00.0%Unchanged
Federated Hermes, Inc.2,873$6.78K0.00%+2,365+465.6%Added
Ameritas Investment Partners, Inc.2,570$6.07K0.00%00.0%Unchanged
Legal & General Group Plc2,565$6.05K0.00%−562−18.0%Reduced
Assetmark, Inc2,325$5.49K0.00%+451+24.1%Added
New York State Common Retirement Fund2,090$4.93K0.00%+96+4.8%Added
China Universal Asset Management Co., Ltd.1,435$3.39K0.00%+702+95.8%Added
Citigroup Inc774$1.83K0.00%−9,942−92.8%Reduced
Russell Investments Group, Ltd.613$1.45K0.00%−781−56.0%Reduced
Clearstead Advisors, LLC610$1.44K0.00%00.0%Unchanged
Glassman Wealth Services565$1.33K0.00%+565New
Comerica Bank549$1.30K0.00%+549New
Deutsche Bank AG509$1.20K0.00%−15,392−96.8%Reduced
Advisor Group Holdings, Inc.215$5050.00%−17−7.3%Reduced
US Bancorp84$1980.00%−354−80.8%Reduced
Nisa Investment Advisors, LLC30$710.00%+30New
Point72 Asset Management, L.P.1$20.00%−5,348−100.0%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)1$20.00%00.0%Unchanged
Simplex Trading, LLC265$00.00%−117−30.6%Reduced
Daiwa Securities Group Inc.162$00.00%00.0%Unchanged
Covestor Ltd17$00.00%−3−15.0%Reduced
Cormorant Asset Management, LP0$00.00%−5,150,000−100.0%Sold out
Avoro Capital Advisors LLC0$00.00%−3,500,000−100.0%Sold out
Ra Capital Management, L.P.0$00.00%−2,971,231−100.0%Sold out
Janus Henderson Group PLC0$00.00%−829,425−100.0%Sold out
Wellington Management Group LLP0$00.00%−502,375−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−265,384−100.0%Sold out
Bank of Montreal0$00.00%−99,240−100.0%Sold out
HRT Financial LP0$00.00%−95,264−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−84,000−100.0%Sold out
Trexquant Investment LP0$00.00%−46,524−100.0%Sold out
MetLife Investment Management0$00.00%−22,045−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−18,499−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−16,100−100.0%Sold out