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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Design Therapeutics, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
88
+1 vs. Q3 2023
Shares held
31.7M
−1.15M (−3.5%) vs. Q3 2023
Total value
$84.0M
+$6.48M (+8.4%) vs. Q3 2023
New holders
15
36 more added
Sold out
14
24 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 88 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ4 2023: $84.0M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q3 2023.

Institutions holding DSGN in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Sr One Capital Management, LP6,526,476$17.3M7.26%00.0%Unchanged
Logos Global Management LP5,032,501$13.3M1.48%00.0%Unchanged
BlackRock Inc.2,380,242$6.31M0.00%−23,673−1.0%Reduced
Citadel Advisors LLC1,832,254$4.86M0.00%−868,299−32.2%Reduced
Baker Bros. Advisors LP1,500,000$3.98M0.05%00.0%Unchanged
Tang Capital Management LLC1,480,675$3.92M0.36%+130,675+9.7%Added
BML Capital Management, LLC1,029,478$2.73M2.15%+1,029,478New
Almitas Capital LLC1,026,068$2.72M0.94%+1,026,068New
Goldman Sachs Group Inc1,023,723$2.71M0.00%+579,225+130.3%Added
Vanguard Group Inc997,159$2.64M0.00%+10,448+1.1%Added
State Street Corp695,224$1.84M0.00%+2,501+0.4%Added
Geode Capital Management, LLC662,744$1.76M0.00%+28,024+4.4%Added
Renaissance Technologies LLC648,800$1.72M0.00%+484,600+295.1%Added
Two Sigma Advisers, LP585,000$1.55M0.00%+472,200+418.6%Added
Jacobs Levy Equity Management, Inc549,118$1.46M0.01%+549,118New
Morgan Stanley543,481$1.44M0.00%+183,223+50.9%Added
Two Sigma Investments, LP428,171$1.13M0.00%+364,336+570.7%Added
Millennium Management LLC420,063$1.11M0.00%−409,417−49.4%Reduced
Northern Trust Corp372,927$988.3K0.00%+49,668+15.4%Added
Walleye Capital LLC362,387$960.3K0.01%−11,126−3.0%Reduced
Prescott Group Capital Management, L.L.C.343,000$909.0K0.16%+163,000+90.6%Added
D. E. Shaw & Co., Inc.290,628$770.2K0.00%+278,888+2,375.5%Added
Prosight Management, LP280,000$742.0K0.30%−923,745−76.7%Reduced
Assenagon Asset Management S.A.245,227$649.9K0.00%−2,820−1.1%Reduced
Candriam Luxembourg S.C.A.225,000$596.3K0.00%00.0%Unchanged
Acadian Asset Management LLC180,741$478.0K0.00%+180,741New
Charles Schwab Investment Management Inc175,645$465.5K0.00%+2,100+1.2%Added
Nuveen Asset Management, LLC158,004$418.7K0.00%+4,617+3.0%Added
Bridgeway Capital Management, LLC145,900$386.6K0.01%+65,400+81.2%Added
Bank of New York Mellon Corp120,792$320.1K0.00%00.0%Unchanged
Barclays PLC110,954$294.0K0.00%+39,276+54.8%Added
Bank of America Corp86,338$228.8K0.00%+37,603+77.2%Added
FMR LLC79,012$209.4K0.00%+8,954+12.8%Added
STRS Ohio72,800$192.0K0.00%00.0%Unchanged
Gsa Capital Partners LLP72,292$192.0K0.02%+28,711+65.9%Added
Cubist Systematic Strategies, LLC57,681$152.9K0.00%+30,744+114.1%Added
AQR Capital Management LLC56,240$149.0K0.00%+56,240New
Jane Street Group, LLC54,693$144.9K0.00%+25,310+86.1%Added
Ameriprise Financial Inc53,015$140.5K0.00%+53,015New
Rhumbline Advisers50,864$134.8K0.00%−1,612−3.1%Reduced
UBS Group AG50,441$133.7K0.00%+32,377+179.2%Added
Prelude Capital Management, LLC48,600$128.8K0.01%+15,200+45.5%Added
HSBC Holdings PLC45,055$117.6K0.00%+8,565+23.5%Added
Dimensional Fund Advisors LP41,848$111.1K0.00%−12,267−22.7%Reduced
JPMorgan Chase & Co41,260$109.3K0.00%−15,082−26.8%Reduced
HRT Financial LP40,718$107.0K0.00%+40,718New
Squarepoint Ops LLC38,429$101.8K0.00%−4,133−9.7%Reduced
Alliancebernstein L.P.37,500$99.4K0.00%−3,900−9.4%Reduced
Algert Global LLC35,620$94.4K0.00%00.0%Unchanged
PDT Partners, LLC28,401$75.3K0.01%−5,281−15.7%Reduced
Deutsche Bank AG28,094$74.4K0.00%+27,585+5,419.4%Added
Public Employees Retirement System of Ohio26,338$69.8K0.00%+26,338New
Graham Capital Management, L.P.22,569$59.8K0.00%+719+3.3%Added
Tower Research Capital LLC (TRC)21,503$57.0K0.00%+4,983+30.2%Added
Susquehanna International Group, LLP20,896$55.4K0.00%−1,641−7.3%Reduced
SG Americas Securities, LLC18,857$50.0K0.00%−1,050−5.3%Reduced
Prudential Financial Inc18,415$48.8K0.00%00.0%Unchanged
Engineers Gate Manager LP17,914$47.5K0.00%+17,914New
American International Group, Inc.16,289$43.2K0.00%−66−0.4%Reduced
Principal Financial Group Inc15,216$40.3K0.00%−701,602−97.9%Reduced
Voya Investment Management LLC14,090$37.3K0.00%00.0%Unchanged
Corton Capital Inc.12,607$33.4K0.01%−14,527−53.5%Reduced
Occudo Quantitative Strategies LP12,324$32.7K0.00%−88,398−87.8%Reduced
Federated Hermes, Inc.11,999$31.8K0.00%+9,126+317.6%Added
Nisa Investment Advisors, LLC11,560$30.6K0.00%+11,530+38,433.3%Added
Royal Bank of Canada10,799$29.0K0.00%+5,298+96.3%Added
Invesco Ltd.10,937$29.0K0.00%+10,937New
Pale Fire Capital SE10,500$27.8K0.00%+10,500New
Wells Fargo & Company10,022$26.6K0.00%+1,990+24.8%Added
Point72 Middle East FZE9,426$25.0K0.00%+4,501+91.4%Added
California State Teachers Retirement System5,394$14.3K0.00%−1,837−25.4%Reduced
Citigroup Inc4,815$12.8K0.00%+4,041+522.1%Added
Amalgamated Bank2,930$8.00K0.00%−350−10.7%Reduced
Ameritas Investment Partners, Inc.2,570$6.81K0.00%00.0%Unchanged
Legal & General Group Plc2,565$6.80K0.00%00.0%Unchanged
Point72 Asia (Singapore) Pte. Ltd.2,100$5.57K0.00%+2,100New
New York State Common Retirement Fund2,026$5.37K0.00%−64−3.1%Reduced
ADAR1 Capital Management, LLC2,000$5.30K0.00%+2,000New
Simplex Trading, LLC1,962$5.00K0.00%+1,697+640.4%Added
Russell Investments Group, Ltd.1,864$4.94K0.00%+1,251+204.1%Added
Quantbot Technologies LP1,705$4.52K0.00%−2,200−56.3%Reduced
The PNC Financial Services Group, Inc.1,473$3.90K0.00%+1,473New
Group One Trading, L.P.1,400$3.71K0.00%+1,400New
Clearstead Advisors, LLC610$1.62K0.00%00.0%Unchanged
Glassman Wealth Services293$7760.00%−272−48.1%Reduced
Advisor Group Holdings, Inc.15$350.00%−200−93.0%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)1$30.00%00.0%Unchanged
Covestor Ltd34$00.00%+17+100.0%Added
RTW Investments, LP0$00.00%−2,512,986−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−1,025,000−100.0%Sold out
Rock Springs Capital Management LP0$00.00%−460,391−100.0%Sold out
Marshall Wace, LLP0$00.00%−60,542−100.0%Sold out
Jump Financial, LLC0$00.00%−46,700−100.0%Sold out
XTX Topco Ltd0$00.00%−38,472−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−18,313−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−16,299−100.0%Sold out
Assetmark, Inc0$00.00%−2,325−100.0%Sold out
China Universal Asset Management Co., Ltd.0$00.00%−1,435−100.0%Sold out
Comerica Bank0$00.00%−549−100.0%Sold out
US Bancorp0$00.00%−84−100.0%Sold out