Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q1 2024
Institutional positions in Design Therapeutics, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 93
- +5 vs. Q4 2023
- Shares held
- 30.7M
- −989.9K (−3.1%) vs. Q4 2023
- Total value
- $123.9M
- +$39.8M (+47.4%) vs. Q4 2023
- New holders
- 19
- 21 more added
- Sold out
- 14
- 37 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sr One Capital Management, LP | 6,526,476 | $26.3M | 7.22% | 00.0% | Unchanged |
| Logos Global Management LP | 5,032,501 | $20.3M | 2.13% | 00.0% | Unchanged |
| BlackRock Inc. | 2,274,191 | $9.16M | 0.00% | −106,051−4.5% | Reduced |
| Baker Bros. Advisors LP | 1,662,120 | $6.70M | 0.08% | +162,120+10.8% | Added |
| Tang Capital Management LLC | 1,480,975 | $5.97M | 0.62% | +3000.0% | Added |
| Vanguard Group Inc | 1,285,962 | $5.18M | 0.00% | +288,803+29.0% | Added |
| Almitas Capital LLC | 1,026,068 | $4.14M | 1.71% | 00.0% | Unchanged |
| BML Capital Management, LLC | 879,478 | $3.54M | 2.37% | −150,000−14.6% | Reduced |
| Citadel Advisors LLC | 874,777 | $3.53M | 0.00% | −957,477−52.3% | Reduced |
| State Street Corp | 698,986 | $2.82M | 0.00% | +3,762+0.5% | Added |
| Geode Capital Management, LLC | 683,898 | $2.76M | 0.00% | +21,154+3.2% | Added |
| Point72 Asset Management, L.P. | 593,516 | $2.39M | 0.01% | +593,516 | New |
| Goldman Sachs Group Inc | 506,256 | $2.04M | 0.00% | −517,467−50.5% | Reduced |
| Jacobs Levy Equity Management, Inc | 502,020 | $2.02M | 0.01% | −47,098−8.6% | Reduced |
| Millennium Management LLC | 484,468 | $1.95M | 0.00% | +64,405+15.3% | Added |
| Morgan Stanley | 478,092 | $1.93M | 0.00% | −65,389−12.0% | Reduced |
| Renaissance Technologies LLC | 453,400 | $1.83M | 0.00% | −195,400−30.1% | Reduced |
| D. E. Shaw & Co., Inc. | 446,190 | $1.80M | 0.00% | +155,562+53.5% | Added |
| Two Sigma Investments, LP | 422,035 | $1.70M | 0.00% | −6,136−1.4% | Reduced |
| Two Sigma Advisers, LP | 404,000 | $1.63M | 0.00% | −181,000−30.9% | Reduced |
| Acadian Asset Management LLC | 403,546 | $1.63M | 0.01% | +222,805+123.3% | Added |
| Northern Trust Corp | 357,284 | $1.44M | 0.00% | −15,643−4.2% | Reduced |
| Assenagon Asset Management S.A. | 347,794 | $1.40M | 0.00% | +102,567+41.8% | Added |
| Prescott Group Capital Management, L.L.C. | 343,000 | $1.38M | 0.22% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 216,347 | $872.0K | 0.07% | +144,055+199.3% | Added |
| Wellington Management Group LLP | 214,310 | $863.7K | 0.00% | +214,310 | New |
| Walleye Capital LLC | 194,551 | $784.0K | 0.01% | −167,836−46.3% | Reduced |
| Charles Schwab Investment Management Inc | 179,170 | $722.1K | 0.00% | +3,525+2.0% | Added |
| Nuveen Asset Management, LLC | 158,004 | $636.8K | 0.00% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 145,900 | $588.0K | 0.01% | 00.0% | Unchanged |
| Shay Capital LLC | 128,305 | $517.1K | 0.15% | +128,305 | New |
| Bank of New York Mellon Corp | 115,242 | $464.4K | 0.00% | −5,550−4.6% | Reduced |
| Opaleye Management Inc. | 113,038 | $455.5K | 0.10% | +113,038 | New |
| Barclays PLC | 88,908 | $358.3K | 0.00% | −22,046−19.9% | Reduced |
| FMR LLC | 78,341 | $315.7K | 0.00% | −671−0.8% | Reduced |
| Rhumbline Advisers | 52,452 | $211.4K | 0.00% | +1,588+3.1% | Added |
| Ameriprise Financial Inc | 50,515 | $203.6K | 0.00% | −2,500−4.7% | Reduced |
| HSBC Holdings PLC | 48,789 | $196.6K | 0.00% | +3,734+8.3% | Added |
| Prelude Capital Management, LLC | 48,600 | $195.9K | 0.01% | 00.0% | Unchanged |
| Prudential Financial Inc | 46,815 | $188.7K | 0.00% | +28,400+154.2% | Added |
| Bank of America Corp | 45,397 | $183.0K | 0.00% | −40,941−47.4% | Reduced |
| JPMorgan Chase & Co | 38,704 | $156.0K | 0.00% | −2,556−6.2% | Reduced |
| Alliancebernstein L.P. | 37,500 | $151.1K | 0.00% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 36,855 | $148.5K | 0.00% | −4,993−11.9% | Reduced |
| Squarepoint Ops LLC | 36,437 | $146.8K | 0.00% | −1,992−5.2% | Reduced |
| UBS Group AG | 33,033 | $133.1K | 0.00% | −17,408−34.5% | Reduced |
| STRS Ohio | 29,300 | $118.0K | 0.00% | −43,500−59.8% | Reduced |
| Deutsche Bank AG | 28,094 | $113.2K | 0.00% | 00.0% | Unchanged |
| CI Private Wealth, LLC | 26,965 | $108.7K | 0.00% | +26,965 | New |
| Tudor Investment Corp Et Al | 25,327 | $102.1K | 0.00% | +25,327 | New |
| Public Employees Retirement System of Ohio | 23,748 | $95.7K | 0.00% | −2,590−9.8% | Reduced |
| Occudo Quantitative Strategies LP | 23,395 | $94.3K | 0.02% | +11,071+89.8% | Added |
| Mirae Asset Global Investments Co., Ltd. | 14,133 | $77.7K | 0.00% | +14,133 | New |
| Mariner, LLC | 18,674 | $75.3K | 0.00% | +18,674 | New |
| State Board of Administration of Florida Retirement System | 12,630 | $72.9K | 0.00% | +12,630 | New |
| Palumbo Wealth Management LLC | 16,972 | $68.4K | 0.03% | +16,972 | New |
| American International Group, Inc. | 16,150 | $65.1K | 0.00% | −139−0.9% | Reduced |
| XTX Topco Ltd | 15,257 | $61.5K | 0.01% | +15,257 | New |
| Cubist Systematic Strategies, LLC | 13,384 | $53.9K | 0.00% | −44,297−76.8% | Reduced |
| Principal Financial Group Inc | 12,497 | $50.4K | 0.00% | −2,719−17.9% | Reduced |
| AQR Capital Management LLC | 11,748 | $47.3K | 0.00% | −44,492−79.1% | Reduced |
| Nisa Investment Advisors, LLC | 11,560 | $46.6K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 11,506 | $46.4K | 0.00% | +1,484+14.8% | Added |
| Simplicity Wealth,LLC | 11,495 | $46.3K | 0.00% | +11,495 | New |
| Bleakley Financial Group, LLC | 11,495 | $46.3K | 0.00% | +11,495 | New |
| SG Americas Securities, LLC | 11,316 | $46.0K | 0.00% | −7,541−40.0% | Reduced |
| Susquehanna International Group, LLP | 11,232 | $45.3K | 0.00% | −9,664−46.2% | Reduced |
| Price T Rowe Associates Inc | 11,147 | $45.0K | 0.00% | +11,147 | New |
| Algert Global LLC | 11,080 | $44.7K | 0.00% | −24,540−68.9% | Reduced |
| The PNC Financial Services Group, Inc. | 10,843 | $43.7K | 0.00% | +9,370+636.1% | Added |
| Invesco Ltd. | 10,474 | $42.2K | 0.00% | −463−4.2% | Reduced |
| Federated Hermes, Inc. | 10,318 | $41.6K | 0.00% | −1,681−14.0% | Reduced |
| ADAR1 Capital Management, LLC | 7,200 | $29.0K | 0.01% | +5,200+260.0% | Added |
| Citigroup Inc | 6,329 | $25.5K | 0.00% | +1,514+31.4% | Added |
| Simplex Trading, LLC | 5,019 | $20.0K | 0.00% | +3,057+155.8% | Added |
| Russell Investments Group, Ltd. | 4,311 | $17.4K | 0.00% | +2,447+131.3% | Added |
| California State Teachers Retirement System | 3,294 | $13.3K | 0.00% | −2,100−38.9% | Reduced |
| Tower Research Capital LLC (TRC) | 2,677 | $10.8K | 0.00% | −18,826−87.6% | Reduced |
| Ameritas Investment Partners, Inc. | 2,570 | $10.4K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 2,565 | $10.3K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 2,026 | $8.16K | 0.00% | 00.0% | Unchanged |
| Quantbot Technologies LP | 1,705 | $6.87K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 1,300 | $5.24K | 0.00% | −100−7.1% | Reduced |
| Amalgamated Bank | 1,176 | $5.00K | 0.00% | −1,754−59.9% | Reduced |
| Royal Bank of Canada | 734 | $3.00K | 0.00% | −10,065−93.2% | Reduced |
| Clearstead Advisors, LLC | 610 | $2.78K | 0.00% | 00.0% | Unchanged |
| Private Wealth Management Group, LLC | 558 | $2.25K | 0.00% | +558 | New |
| Massmutual Trust Co FSB | 239 | $963 | 0.00% | +239 | New |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 7 | $28 | 0.00% | +7 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1 | $4 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 32 | $0 | 0.00% | −2−5.9% | Reduced |
| CWM, LLC | 1 | $0 | 0.00% | +1 | New |
| Capital Advisors, Ltd. LLC | 12 | $0 | 0.00% | +12 | New |
| Prosight Management, LP | 0 | $0 | 0.00% | −280,000−100.0% | Sold out |
| Candriam Luxembourg S.C.A. | 0 | $0 | 0.00% | −225,000−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −54,693−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −40,718−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −28,401−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −22,569−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −17,914−100.0% | Sold out |