Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Design Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 95
- +2 vs. Q2 2025
- Shares held
- 34.5M
- −37.9K (−0.1%) vs. Q2 2025
- Total value
- $259.7M
- +$143.4M (+123.2%) vs. Q2 2025
- New holders
- 14
- 17 more added
- Sold out
- 12
- 38 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sr One Capital Management, LP | 6,526,476 | $49.1M | 7.11% | 00.0% | Unchanged |
| Logos Global Management LP | 3,655,000 | $27.5M | 2.72% | −562,627−13.3% | Reduced |
| Point72 Asset Management, L.P. | 3,340,552 | $25.2M | 0.05% | +1,533,334+84.8% | Added |
| BlackRock, Inc. | 2,044,388 | $15.4M | 0.00% | −351,355−14.7% | Reduced |
| Frazier Life Sciences Management, L.P. | 1,953,547 | $14.7M | 0.44% | 00.0% | Unchanged |
| Tang Capital Management LLC | 1,780,975 | $13.4M | 0.52% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 1,712,882 | $12.9M | 0.09% | 00.0% | Unchanged |
| Almitas Capital LLC | 1,530,435 | $11.5M | 2.64% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,443,701 | $10.9M | 0.00% | −27,873−1.9% | Reduced |
| Driehaus Capital Management LLC | 1,076,236 | $8.10M | 0.06% | 00.0% | Unchanged |
| Kynam Capital Management, LP | 1,029,579 | $7.75M | 0.58% | 00.0% | Unchanged |
| FMR LLC | 740,849 | $5.58M | 0.00% | −210,349−22.1% | Reduced |
| Geode Capital Management, LLC | 695,613 | $5.24M | 0.00% | −98,395−12.4% | Reduced |
| State Street Corp | 634,397 | $4.78M | 0.00% | −84,815−11.8% | Reduced |
| Acadian Asset Management LLC | 617,489 | $4.65M | 0.01% | −9,859−1.6% | Reduced |
| Woodline Partners LP | 612,712 | $4.61M | 0.02% | −164,825−21.2% | Reduced |
| MPM Oncology Impact Management LP | 555,187 | $4.18M | 0.68% | 00.0% | Unchanged |
| Citadel Advisors LLC | 554,020 | $4.17M | 0.00% | −286,773−34.1% | Reduced |
| Ra Capital Management, L.P. | 475,699 | $3.58M | 0.04% | +475,699 | New |
| D. E. Shaw & Co., Inc. | 373,276 | $2.81M | 0.00% | −17,372−4.4% | Reduced |
| Northern Trust Corp | 296,529 | $2.23M | 0.00% | −65,989−18.2% | Reduced |
| Dimensional Fund Advisors LP | 279,817 | $2.11M | 0.00% | −33,546−10.7% | Reduced |
| Renaissance Technologies LLC | 274,300 | $2.07M | 0.00% | +6,500+2.4% | Added |
| Goldman Sachs Group Inc | 261,445 | $1.97M | 0.00% | +21,986+9.2% | Added |
| Charles Schwab Investment Management Inc | 247,934 | $1.87M | 0.00% | −3,015−1.2% | Reduced |
| Bridgeway Capital Management, LLC | 188,200 | $1.42M | 0.03% | 00.0% | Unchanged |
| Morgan Stanley | 175,991 | $1.33M | 0.00% | −37,559−17.6% | Reduced |
| Nuveen, LLC | 133,028 | $1.00M | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 117,833 | $887.3K | 0.00% | +86,754+279.1% | Added |
| Barclays PLC | 88,176 | $664.0K | 0.00% | −21,360−19.5% | Reduced |
| Bank of New York Mellon Corp | 87,475 | $658.7K | 0.00% | −7,128−7.5% | Reduced |
| Millennium Management LLC | 68,823 | $518.2K | 0.00% | +68,823 | New |
| Lynx1 Capital Management LP | 65,954 | $496.6K | 0.10% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 59,237 | $446.1K | 0.00% | −30,074−33.7% | Reduced |
| Palumbo Wealth Management LLC | 52,081 | $392.2K | 0.13% | −8,474−14.0% | Reduced |
| American Century Companies Inc | 50,852 | $382.9K | 0.00% | +4,467+9.6% | Added |
| DLD Asset Management, LP | 50,000 | $376.5K | 0.05% | +50,000 | New |
| Rhumbline Advisers | 46,334 | $348.9K | 0.00% | −1,983−4.1% | Reduced |
| Alliancebernstein L.P. | 46,120 | $347.3K | 0.00% | +1,090+2.4% | Added |
| Prudential Financial Inc | 44,825 | $337.5K | 0.00% | −13,100−22.6% | Reduced |
| Two Sigma Advisers, LP | 40,500 | $305.0K | 0.00% | −68,000−62.7% | Reduced |
| China Universal Asset Management Co., Ltd. | 34,982 | $263.4K | 0.02% | +23,580+206.8% | Added |
| HRT Financial LP | 31,903 | $240.0K | 0.00% | +31,903 | New |
| Kennedy Capital Management, Inc. | 29,411 | $221.5K | 0.00% | +14,401+95.9% | Added |
| State of Wisconsin Investment Board | 27,062 | $203.8K | 0.00% | −1,600−5.6% | Reduced |
| Bank of America Corp | 23,907 | $180.0K | 0.00% | −718−2.9% | Reduced |
| JPMorgan Chase & Co | 23,221 | $174.9K | 0.00% | +4,896+26.7% | Added |
| UBS Group AG | 22,693 | $170.9K | 0.00% | −4,649−17.0% | Reduced |
| STRS Ohio | 22,600 | $170.2K | 0.00% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 21,918 | $165.0K | 0.04% | +21,918 | New |
| Velan Capital Investment Management LP | 20,000 | $150.6K | 0.14% | 00.0% | Unchanged |
| Wells Fargo & Company | 18,317 | $137.9K | 0.00% | −1,967−9.7% | Reduced |
| Price T Rowe Associates Inc | 16,314 | $123.0K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 16,081 | $121.1K | 0.00% | +341+2.2% | Added |
| Invesco Ltd. | 14,589 | $109.9K | 0.00% | +225+1.6% | Added |
| Intech Investment Management LLC | 14,155 | $106.6K | 0.00% | −5,513−28.0% | Reduced |
| Susquehanna International Group, LLP | 14,023 | $105.6K | 0.00% | −24,147−63.3% | Reduced |
| AQR Capital Management LLC | 13,664 | $102.9K | 0.00% | −15,062−52.4% | Reduced |
| XTX Topco Ltd | 11,868 | $89.4K | 0.00% | +11,868 | New |
| Nisa Investment Advisors, LLC | 11,824 | $89.0K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 10,724 | $80.8K | 0.00% | −7,233−40.3% | Reduced |
| MetLife Investment Management | 10,320 | $77.7K | 0.00% | +10,320 | New |
| Police & Firemen's Retirement System of New Jersey | 6,598 | $49.7K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 6,377 | $48.0K | 0.00% | +2,618+69.6% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 5,702 | $42.9K | 0.01% | +5,702 | New |
| BNP Paribas Arbitrage, SA | 5,133 | $38.7K | 0.00% | +1,310+34.3% | Added |
| Caz Investments LP | 5,000 | $37.6K | 0.07% | −2,500−33.3% | Reduced |
| Ameritas Investment Partners, Inc. | 2,570 | $19.4K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,202 | $16.6K | 0.00% | +9+0.4% | Added |
| Legal & General Group Plc | 2,077 | $15.7K | 0.00% | −1,001−32.5% | Reduced |
| New York State Common Retirement Fund | 2,026 | $15.3K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 1,969 | $14.8K | 0.00% | +1,969 | New |
| Tower Research Capital LLC (TRC) | 1,959 | $14.8K | 0.00% | −7,739−79.8% | Reduced |
| The PNC Financial Services Group, Inc. | 1,823 | $13.7K | 0.00% | +152+9.1% | Added |
| Sterling Capital Management LLC | 1,648 | $12.4K | 0.00% | +807+96.0% | Added |
| Citigroup Inc | 1,590 | $12.0K | 0.00% | −12,058−88.3% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1,227 | $9.24K | 0.00% | −590−32.5% | Reduced |
| GF Fund Management Co. Ltd. | 1,213 | $9.13K | 0.00% | −236−16.3% | Reduced |
| Amalgamated Bank | 1,176 | $9.00K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 610 | $4.59K | 0.00% | 00.0% | Unchanged |
| Private Wealth Management Group, LLC | 558 | $4.20K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 445 | $4.00K | 0.00% | −3,367−88.3% | Reduced |
| GAMMA Investing LLC | 443 | $3.34K | 0.00% | +443 | New |
| Farther Finance Advisors, LLC | 385 | $2.90K | 0.00% | +366+1,926.3% | Added |
| Optiver Holding B.V. | 328 | $2.47K | 0.00% | +328 | New |
| UMA Financial Services, Inc. | 268 | $2.02K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 222 | $2.00K | 0.00% | −49−18.1% | Reduced |
| Massmutual Trust Co FSB | 239 | $1.80K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 235 | $1.77K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 194 | $1.46K | 0.00% | +194 | New |
| Daiwa Securities Group Inc. | 100 | $1.00K | 0.00% | −250−71.4% | Reduced |
| Rise Advisors, LLC | 130 | $979 | 0.00% | 00.0% | Unchanged |
| Versant Capital Management, Inc | 71 | $535 | 0.00% | +71 | New |
| Larson Financial Group LLC | 3 | $23 | 0.00% | +3 | New |
| Capital Advisors, Ltd. LLC | 12 | $0 | 0.00% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −59,975−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −42,408−100.0% | Sold out |
| Assenagon Asset Management S.A. | 0 | $0 | 0.00% | −31,125−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −28,094−100.0% | Sold out |
| CI Private Wealth, LLC | 0 | $0 | 0.00% | −26,965−100.0% | Sold out |