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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Design Therapeutics, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
95
+2 vs. Q1 2024
Shares held
32.1M
+1.37M (+4.5%) vs. Q1 2024
Total value
$107.5M
−$16.4M (−13.2%) vs. Q1 2024
New holders
15
36 more added
Sold out
13
27 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 95 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ2 2024: $107.5M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q1 2024.

Institutions holding DSGN in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Sr One Capital Management, LP6,526,476$21.9M6.85%00.0%Unchanged
Logos Global Management LP5,032,501$16.9M1.94%00.0%Unchanged
BlackRock Inc.2,304,948$7.72M0.00%+30,757+1.4%Added
Baker Bros. Advisors LP1,695,294$5.68M0.07%+33,174+2.0%Added
Tang Capital Management LLC1,480,975$4.96M0.51%00.0%Unchanged
Vanguard Group Inc1,296,788$4.34M0.00%+10,826+0.8%Added
Almitas Capital LLC1,253,248$4.20M1.75%+227,180+22.1%Added
Frazier Life Sciences Management, L.P.1,195,179$4.00M0.19%+1,195,179New
Point72 Asset Management, L.P.990,801$3.32M0.01%+397,285+66.9%Added
Geode Capital Management, LLC707,971$2.37M0.00%+24,073+3.5%Added
State Street Corp695,423$2.33M0.00%−3,563−0.5%Reduced
Millennium Management LLC610,803$2.05M0.00%+126,335+26.1%Added
Goldman Sachs Group Inc603,705$2.02M0.00%+97,449+19.2%Added
Acadian Asset Management LLC583,160$1.95M0.01%+179,614+44.5%Added
D. E. Shaw & Co., Inc.535,784$1.79M0.00%+89,594+20.1%Added
Jacobs Levy Equity Management, Inc476,258$1.60M0.01%−25,762−5.1%Reduced
BML Capital Management, LLC421,749$1.41M1.03%−457,729−52.0%Reduced
Two Sigma Investments, LP402,715$1.35M0.00%−19,320−4.6%Reduced
Two Sigma Advisers, LP400,100$1.34M0.00%−3,900−1.0%Reduced
Morgan Stanley389,437$1.30M0.00%−88,655−18.5%Reduced
Renaissance Technologies LLC384,075$1.29M0.00%−69,325−15.3%Reduced
Assenagon Asset Management S.A.347,794$1.17M0.00%00.0%Unchanged
Prescott Group Capital Management, L.L.C.343,000$1.15M0.18%00.0%Unchanged
Northern Trust Corp337,345$1.13M0.00%−19,939−5.6%Reduced
Citadel Advisors LLC304,630$1.02M0.00%−570,147−65.2%Reduced
Wellington Management Group LLP256,627$859.7K0.00%+42,317+19.7%Added
Bridgeway Capital Management, LLC235,600$789.3K0.02%+89,700+61.5%Added
Nuveen Asset Management, LLC212,554$712.1K0.00%+54,550+34.5%Added
Gsa Capital Partners LLP209,953$703.0K0.05%−6,394−3.0%Reduced
Opaleye Management Inc.205,000$686.8K0.16%+91,962+81.4%Added
Charles Schwab Investment Management Inc179,960$602.9K0.00%+790+0.4%Added
Bank of New York Mellon Corp118,110$395.7K0.00%+2,868+2.5%Added
Squarepoint Ops LLC89,955$301.3K0.00%+53,518+146.9%Added
FMR LLC81,016$271.4K0.00%+2,675+3.4%Added
Dimensional Fund Advisors LP80,953$271.2K0.00%+44,098+119.7%Added
Barclays PLC72,033$241.3K0.00%−16,875−19.0%Reduced
Prudential Financial Inc63,215$211.8K0.00%+16,400+35.0%Added
Walleye Capital LLC60,212$201.7K0.00%−134,339−69.1%Reduced
Jane Street Group, LLC57,905$194.0K0.00%+57,905New
Rhumbline Advisers53,067$177.8K0.00%+615+1.2%Added
Ameriprise Financial Inc50,515$169.2K0.00%00.0%Unchanged
HSBC Holdings PLC44,470$145.9K0.00%−4,319−8.9%Reduced
Alliancebernstein L.P.42,090$141.0K0.00%+4,590+12.2%Added
Caz Investments LP40,000$134.0K0.20%+40,000New
Palumbo Wealth Management LLC33,054$110.7K0.05%+16,082+94.8%Added
Prelude Capital Management, LLC32,956$110.4K0.01%−15,644−32.2%Reduced
STRS Ohio32,600$109.2K0.00%+3,300+11.3%Added
Bank of America Corp32,284$108.2K0.00%−13,113−28.9%Reduced
Deutsche Bank AG28,094$94.1K0.00%00.0%Unchanged
PDT Partners, LLC27,127$90.9K0.01%+27,127New
Verition Fund Management LLC27,045$90.6K0.00%+27,045New
CI Private Wealth, LLC26,965$90.3K0.00%00.0%Unchanged
Marshall Wace, LLP24,280$81.3K0.00%+24,280New
Cubist Systematic Strategies, LLC23,497$78.7K0.00%+10,113+75.6%Added
Public Employees Retirement System of Ohio22,393$75.0K0.00%−1,355−5.7%Reduced
Susquehanna International Group, LLP21,726$72.8K0.00%+10,494+93.4%Added
American Century Companies Inc21,333$71.5K0.00%+21,333New
Jump Financial, LLC20,087$67.3K0.00%+20,087New
Tudor Investment Corp Et Al19,865$66.5K0.00%−5,462−21.6%Reduced
Mariner, LLC18,674$62.6K0.00%00.0%Unchanged
Corebridge Financial, Inc.16,892$56.6K0.00%+16,892New
Mirae Asset Global ETFs Holdings Ltd.16,270$54.5K0.00%+16,270New
JPMorgan Chase & Co14,184$47.5K0.00%−24,520−63.4%Reduced
Wells Fargo & Company13,797$46.2K0.00%+2,291+19.9%Added
UBS Group AG13,360$44.8K0.00%−19,673−59.6%Reduced
Algert Global LLC12,416$41.6K0.00%+1,336+12.1%Added
Nisa Investment Advisors, LLC11,855$39.7K0.00%+295+2.6%Added
Simplicity Wealth,LLC11,632$39.0K0.00%+137+1.2%Added
Bleakley Financial Group, LLC11,632$39.0K0.00%+137+1.2%Added
AQR Capital Management LLC11,083$37.1K0.00%−665−5.7%Reduced
Virtu Financial LLC11,070$37.0K0.00%+11,070New
Price T Rowe Associates Inc10,284$35.0K0.00%−863−7.7%Reduced
The PNC Financial Services Group, Inc.9,692$32.5K0.00%−1,151−10.6%Reduced
Russell Investments Group, Ltd.8,244$27.6K0.00%+3,933+91.2%Added
Citigroup Inc7,234$24.2K0.00%+905+14.3%Added
Tower Research Capital LLC (TRC)6,042$20.2K0.00%+3,365+125.7%Added
Federated Hermes, Inc.4,200$14.1K0.00%−6,118−59.3%Reduced
Qube Research & Technologies Ltd2,986$10.0K0.00%+2,986New
Royal Bank of Canada2,953$10.0K0.00%+2,219+302.3%Added
Ameritas Investment Partners, Inc.2,570$8.61K0.00%00.0%Unchanged
Legal & General Group Plc2,565$8.59K0.00%00.0%Unchanged
California State Teachers Retirement System2,275$7.62K0.00%−1,019−30.9%Reduced
New York State Common Retirement Fund2,026$6.79K0.00%00.0%Unchanged
Point72 Asia (Singapore) Pte. Ltd.1,288$4.32K0.00%+1,288New
Simplex Trading, LLC1,295$4.00K0.00%−3,724−74.2%Reduced
Amalgamated Bank1,176$4.00K0.00%00.0%Unchanged
Group One Trading, L.P.1,100$3.69K0.00%−200−15.4%Reduced
Clearstead Advisors, LLC610$2.04K0.00%00.0%Unchanged
Private Wealth Management Group, LLC558$1.87K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.244$8180.00%+244New
Massmutual Trust Co FSB239$8010.00%00.0%Unchanged
Principal Securities, Inc.74$2480.00%+74New
CWM, LLC98$00.00%+97+9,700.0%Added
Capital Advisors, Ltd. LLC12$00.00%00.0%Unchanged
Covestor Ltd22$00.00%−10−31.3%Reduced
Shay Capital LLC0$00.00%−128,305−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−23,395−100.0%Sold out
Mirae Asset Global Investments Co., Ltd.0$00.00%−14,133−100.0%Sold out
State Board of Administration of Florida Retirement System0$00.00%−12,630−100.0%Sold out
American International Group, Inc.0$00.00%−16,150−100.0%Sold out