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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Design Therapeutics, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
79
+5 vs. Q2 2022
Shares held
39.9M
+1.22M (+3.1%) vs. Q2 2022
Total value
$667.2M
+$125.6M (+23.2%) vs. Q2 2022
New holders
15
33 more added
Sold out
10
18 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 79 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ3 2022: $667.2M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q2 2022.

Institutions holding DSGN in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Sr One Capital Management, LP5,626,476$94.1M43.01%00.0%Unchanged
Cormorant Asset Management, LP5,000,000$83.6M5.88%−500,000−9.1%Reduced
BlackRock Inc.3,599,125$60.2M0.00%+59,189+1.7%Added
Logos Global Management LP2,797,501$46.8M5.77%00.0%Unchanged
Ra Capital Management, L.P.2,773,231$46.4M0.99%+586,595+26.8%Added
EcoR1 Capital, LLC2,519,268$42.1M1.25%−114,910−4.4%Reduced
Citadel Advisors LLC2,421,732$40.5M0.05%−123,926−4.9%Reduced
Avoro Capital Advisors LLC2,222,222$37.2M0.69%00.0%Unchanged
Vanguard Group Inc1,551,750$25.9M0.00%+271,706+21.2%Added
Janus Henderson Group PLC1,503,811$25.1M0.02%+420,971+38.9%Added
Baker Bros. Advisors LP1,436,636$24.0M0.16%00.0%Unchanged
FMR LLC1,082,862$18.1M0.00%+55,922+5.4%Added
Goldman Sachs Group Inc993,645$16.6M0.00%+902,408+989.1%Added
Wellington Management Group LLP948,773$15.9M0.00%−109,876−10.4%Reduced
State Street Corp909,469$15.2M0.00%+459,688+102.2%Added
Principal Financial Group Inc819,986$13.7M0.01%+66,293+8.8%Added
Geode Capital Management, LLC576,709$9.64M0.00%+141,584+32.5%Added
Rock Springs Capital Management LP460,391$7.70M0.20%00.0%Unchanged
Northern Trust Corp283,695$4.74M0.00%+25,673+9.9%Added
Tekla Capital Management LLC280,523$4.69M0.19%+172,109+158.8%Added
Price T Rowe Associates Inc280,120$4.68M0.00%−72,989−20.7%Reduced
Charles Schwab Investment Management Inc224,560$3.75M0.00%+89,785+66.6%Added
Millennium Management LLC141,498$2.37M0.00%+141,498New
Dimensional Fund Advisors LP128,872$2.16M0.00%+100,728+357.9%Added
Bank of New York Mellon Corp125,207$2.09M0.00%+22,823+22.3%Added
Integral Health Asset Management, LLC125,000$2.09M0.42%+125,000New
Nuveen Asset Management, LLC110,134$1.84M0.00%−1,327−1.2%Reduced
Ghost Tree Capital, LLC100,000$1.67M0.68%−175,000−63.6%Reduced
JPMorgan Chase & Co93,152$1.56M0.00%+74,863+409.3%Added
Bank of America Corp66,889$1.12M0.00%+38,914+139.1%Added
Morgan Stanley58,935$985.0K0.00%+20,103+51.8%Added
ExodusPoint Capital Management, LP51,841$867.0K0.01%+51,841New
Rhumbline Advisers51,772$866.0K0.00%+3,544+7.3%Added
Manufacturers Life Insurance Company, The42,285$709.0K0.00%−343−0.8%Reduced
HighVista Strategies LLC38,152$638.0K0.36%+38,152New
Bellevue Group AG34,881$583.0K0.01%+34,881New
Citigroup Inc34,267$573.0K0.00%+25,753+302.5%Added
Rafferty Asset Management, LLC31,051$519.0K0.01%+31,051New
Tudor Investment Corp Et Al27,866$466.0K0.01%+14,966+116.0%Added
Voya Investment Management LLC27,247$455.6K0.00%+14,675+116.7%Added
New York State Common Retirement Fund24,246$405.0K0.00%+2,432+11.1%Added
MetLife Investment Management22,045$368.6K0.00%+5,160+30.6%Added
Barclays PLC21,598$361.0K0.00%−183,967−89.5%Reduced
Alliancebernstein L.P.21,200$354.0K0.00%+7,200+51.4%Added
DekaBank Deutsche Girozentrale18,700$317.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP18,316$306.0K0.00%−5,588−23.4%Reduced
TD Asset Management Inc16,318$274.0K0.00%−7,300−30.9%Reduced
American International Group, Inc.16,086$269.0K0.00%+227+1.4%Added
Mirae Asset Global Investments Co., Ltd.15,526$259.0K0.00%+15,526New
Virtus Investment Advisers, Inc.14,400$241.0K0.11%+14,400New
Deutsche Bank AG13,759$230.0K0.00%−2,261−14.1%Reduced
California State Teachers Retirement System13,374$224.0K0.00%−1,115−7.7%Reduced
State Board of Administration of Florida Retirement System12,630$211.0K0.00%00.0%Unchanged
Trexquant Investment LP11,296$189.0K0.01%+11,296New
Balyasny Asset Management LLC11,134$186.0K0.00%+11,134New
Invesco Ltd.10,058$168.0K0.00%−79−0.8%Reduced
SG Americas Securities, LLC9,936$166.0K0.00%−1,876−15.9%Reduced
Tower Research Capital LLC (TRC)9,010$151.0K0.00%+2,951+48.7%Added
Virtus ETF Advisers LLC7,775$130.0K0.05%+59+0.8%Added
Amalgamated Bank4,291$72.0K0.00%00.0%Unchanged
Legal & General Group Plc3,127$52.0K0.00%−120−3.7%Reduced
Ameritas Investment Partners, Inc.2,570$42.0K0.00%+515+25.1%Added
Metropolitan Life Insurance Co2,027$33.9K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)1,329$22.0K0.00%00.0%Unchanged
Russell Investments Group, Ltd.992$16.0K0.00%−1,352−57.7%Reduced
Assetmark, Inc752$13.0K0.00%+110+17.1%Added
China Universal Asset Management Co., Ltd.523$9.00K0.00%+523New
Wells Fargo & Company406$7.00K0.00%−30−6.9%Reduced
Royal Bank of Canada414$7.00K0.00%+224+117.9%Added
Advisor Group Holdings, Inc.321$5.00K0.00%+88+37.8%Added
Daiwa Securities Group Inc.162$3.00K0.00%00.0%Unchanged
Credit Suisse AG192$3.00K0.00%+161+519.4%Added
Allspring Global Investments Holdings, LLC206$3.00K0.00%+206New
Howe & Rusling Inc70$1.00K0.00%+26+59.1%Added
FourThought Financial, LLC44$1.00K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.61$1.00K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC34$1.00K0.00%+34New
Lindbrook Capital, LLC78$1.00K0.00%+78New
Covestor Ltd5$00.00%+5New
Vivo Capital, LLC0$00.00%−476,589−100.0%Sold out
Artal Group S.A.0$00.00%−400,000−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−300,000−100.0%Sold out
Eventide Asset Management, LLC0$00.00%−281,569−100.0%Sold out
HRT Financial LP0$00.00%−40,523−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−26,696−100.0%Sold out
Jane Street Group, LLC0$00.00%−12,705−100.0%Sold out
Fred Alger Management, LLC0$00.00%−6,578−100.0%Sold out
Captrust Financial Advisors0$00.00%−143−100.0%Sold out
State of Wyoming0$00.00%−122−100.0%Sold out