Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q1 2023
Institutional positions in Design Therapeutics, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 96
- +13 vs. Q4 2022
- Shares held
- 38.7M
- −1.68M (−4.2%) vs. Q4 2022
- Total value
- $223.3M
- −$190.9M (−46.1%) vs. Q4 2022
- New holders
- 32
- 23 more added
- Sold out
- 19
- 27 more reduced
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sr One Capital Management, LP | 6,526,476 | $37.7M | 14.03% | 00.0% | Unchanged |
| Cormorant Asset Management, LP | 5,150,000 | $29.7M | 1.96% | 00.0% | Unchanged |
| Avoro Capital Advisors LLC | 3,500,000 | $20.2M | 0.30% | +1,227,778+54.0% | Added |
| BlackRock Inc. | 3,185,891 | $18.4M | 0.00% | −322,133−9.2% | Reduced |
| Ra Capital Management, L.P. | 2,971,231 | $17.1M | 0.39% | 00.0% | Unchanged |
| Citadel Advisors LLC | 2,865,167 | $16.5M | 0.02% | +362,606+14.5% | Added |
| Logos Global Management LP | 2,797,501 | $16.1M | 2.31% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,283,043 | $7.40M | 0.00% | −278,657−17.8% | Reduced |
| FMR LLC | 957,903 | $5.53M | 0.00% | −161,634−14.4% | Reduced |
| Janus Henderson Group PLC | 843,718 | $4.87M | 0.00% | −262,141−23.7% | Reduced |
| Millennium Management LLC | 790,213 | $4.56M | 0.01% | +273,402+52.9% | Added |
| Principal Financial Group Inc | 719,937 | $4.15M | 0.00% | −62,772−8.0% | Reduced |
| State Street Corp | 711,528 | $4.11M | 0.00% | −2,325,932−76.6% | Reduced |
| Geode Capital Management, LLC | 633,008 | $3.65M | 0.00% | +29,995+5.0% | Added |
| Baker Bros. Advisors LP | 626,884 | $3.62M | 0.02% | −65,247−9.4% | Reduced |
| Wellington Management Group LLP | 550,332 | $3.18M | 0.00% | −192,408−25.9% | Reduced |
| Rock Springs Capital Management LP | 460,391 | $2.66M | 0.06% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 304,069 | $1.75M | 0.00% | +279,613+1,143.3% | Added |
| Goldman Sachs Group Inc | 300,624 | $1.73M | 0.00% | +26,153+9.5% | Added |
| Northern Trust Corp | 275,768 | $1.59M | 0.00% | −3,362−1.2% | Reduced |
| Charles Schwab Investment Management Inc | 230,347 | $1.33M | 0.00% | −565−0.2% | Reduced |
| Jane Street Group, LLC | 202,724 | $1.17M | 0.00% | +202,724 | New |
| Marshall Wace, LLP | 180,919 | $1.04M | 0.00% | +68,101+60.4% | Added |
| Two Sigma Investments, LP | 179,096 | $1.03M | 0.00% | +144,003+410.3% | Added |
| Cubist Systematic Strategies, LLC | 178,284 | $1.03M | 0.01% | +68,981+63.1% | Added |
| Ergoteles LLC | 177,337 | $1.02M | 0.04% | +177,337 | New |
| Assenagon Asset Management S.A. | 168,215 | $970.6K | 0.00% | +168,215 | New |
| ExodusPoint Capital Management, LP | 156,138 | $901.0K | 0.01% | +105,407+207.8% | Added |
| HRT Financial LP | 124,963 | $721.0K | 0.01% | +124,963 | New |
| Bank of New York Mellon Corp | 124,053 | $715.8K | 0.00% | −2,431−1.9% | Reduced |
| Nuveen Asset Management, LLC | 115,800 | $668.0K | 0.00% | +21,728+23.1% | Added |
| D. E. Shaw & Co., Inc. | 111,298 | $642.2K | 0.00% | +111,298 | New |
| Squarepoint Ops LLC | 109,214 | $630.2K | 0.00% | +109,214 | New |
| Renaissance Technologies LLC | 101,751 | $587.0K | 0.00% | +101,751 | New |
| Gsa Capital Partners LLP | 97,900 | $565.0K | 0.06% | +84,281+618.8% | Added |
| Dimensional Fund Advisors LP | 76,485 | $441.2K | 0.00% | −77,635−50.4% | Reduced |
| Morgan Stanley | 69,377 | $400.3K | 0.00% | +27,953+67.5% | Added |
| PDT Partners, LLC | 59,969 | $346.0K | 0.05% | +59,969 | New |
| Jump Financial, LLC | 58,800 | $339.3K | 0.01% | +28,400+93.4% | Added |
| Bank of America Corp | 56,243 | $324.5K | 0.00% | −239,617−81.0% | Reduced |
| Rhumbline Advisers | 51,688 | $298.0K | 0.00% | +72+0.1% | Added |
| Trexquant Investment LP | 50,839 | $293.3K | 0.01% | +50,839 | New |
| Two Sigma Advisers, LP | 46,700 | $269.5K | 0.00% | +46,700 | New |
| Verition Fund Management LLC | 44,180 | $254.9K | 0.00% | +44,180 | New |
| State of Wisconsin Investment Board | 43,100 | $248.7K | 0.00% | +43,100 | New |
| Alliancebernstein L.P. | 31,200 | $180.0K | 0.00% | +3,600+13.0% | Added |
| Tudor Investment Corp Et Al | 27,639 | $159.0K | 0.00% | +9,955+56.3% | Added |
| JPMorgan Chase & Co | 25,956 | $150.0K | 0.00% | +6,156+31.1% | Added |
| Deutsche Bank AG | 24,856 | $143.4K | 0.00% | +7,015+39.3% | Added |
| Centiva Capital, LP | 23,572 | $136.0K | 0.01% | +23,572 | New |
| MetLife Investment Management | 22,045 | $127.2K | 0.00% | 00.0% | Unchanged |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 19,306 | $111.4K | 0.00% | +2,617+15.7% | Added |
| New York State Common Retirement Fund | 17,634 | $101.7K | 0.00% | −6,832−27.9% | Reduced |
| Barclays PLC | 17,217 | $99.3K | 0.00% | −113,782−86.9% | Reduced |
| American International Group, Inc. | 16,353 | $94.4K | 0.00% | +326+2.0% | Added |
| Mirae Asset Global Investments Co., Ltd. | 15,512 | $89.5K | 0.00% | −36−0.2% | Reduced |
| SG Americas Securities, LLC | 15,040 | $87.0K | 0.00% | +15,040 | New |
| Manufacturers Life Insurance Company, The | 13,627 | $78.6K | 0.00% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 13,400 | $77.3K | 0.00% | +13,400 | New |
| Voya Investment Management LLC | 13,162 | $75.9K | 0.00% | 00.0% | Unchanged |
| Occudo Quantitative Strategies LP | 12,652 | $73.0K | 0.01% | +12,652 | New |
| State Board of Administration of Florida Retirement System | 12,630 | $72.9K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 12,598 | $72.7K | 0.00% | −929−6.9% | Reduced |
| Atom Investors LP | 11,890 | $68.6K | 0.04% | +11,890 | New |
| Virtus ETF Advisers LLC | 11,396 | $65.8K | 0.04% | −4,378−27.8% | Reduced |
| Quantbot Technologies LP | 10,853 | $62.6K | 0.00% | +10,853 | New |
| Point72 Asset Management, L.P. | 10,130 | $58.5K | 0.00% | +10,130 | New |
| Point72 Middle East FZE | 9,364 | $54.0K | 0.00% | +9,364 | New |
| Wells Fargo & Company | 5,994 | $34.6K | 0.00% | +5,994 | New |
| Amalgamated Bank | 3,506 | $20.0K | 0.00% | −785−18.3% | Reduced |
| Citigroup Inc | 3,407 | $19.7K | 0.00% | −106,253−96.9% | Reduced |
| Legal & General Group Plc | 3,127 | $18.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 2,570 | $14.8K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 2,066 | $12.0K | 0.00% | −1,853−47.3% | Reduced |
| Tower Research Capital LLC (TRC) | 2,099 | $12.0K | 0.00% | −1,142−35.2% | Reduced |
| Metropolitan Life Insurance Co | 2,016 | $11.6K | 0.00% | −233−10.4% | Reduced |
| Assetmark, Inc | 1,658 | $9.57K | 0.00% | +547+49.2% | Added |
| Lindbrook Capital, LLC | 1,535 | $8.86K | 0.00% | +1,535 | New |
| Signaturefd, LLC | 1,349 | $7.78K | 0.00% | +1,349 | New |
| Russell Investments Group, Ltd. | 992 | $5.72K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 758 | $4.37K | 0.00% | +190+33.5% | Added |
| Federated Hermes, Inc. | 641 | $3.70K | 0.00% | −103−13.8% | Reduced |
| Quadrant Capital Group LLC | 616 | $3.56K | 0.00% | +616 | New |
| Clearstead Advisors, LLC | 610 | $3.52K | 0.00% | +610 | New |
| Simplex Trading, LLC | 537 | $3.00K | 0.00% | +537 | New |
| US Bancorp | 479 | $2.76K | 0.00% | +479 | New |
| UBS Group AG | 206 | $1.19K | 0.00% | −155,821−99.9% | Reduced |
| Advisor Group Holdings, Inc. | 203 | $1.17K | 0.00% | −17−7.7% | Reduced |
| Daiwa Securities Group Inc. | 162 | $1.00K | 0.00% | 00.0% | Unchanged |
| Ellevest, Inc. | 100 | $577 | 0.00% | +100 | New |
| EverSource Wealth Advisors, LLC | 79 | $456 | 0.00% | +79 | New |
| Parallel Advisors, LLC | 50 | $289 | 0.00% | +50 | New |
| Allworth Financial LP | 36 | $208 | 0.00% | +36 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1 | $6 | 0.00% | −1,114−99.9% | Reduced |
| Covestor Ltd | 8 | $0 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 17 | $0 | 0.00% | +17 | New |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −884,903−100.0% | Sold out |
| Rafferty Asset Management, LLC | 0 | $0 | 0.00% | −243,585−100.0% | Sold out |
| Ghost Tree Capital, LLC | 0 | $0 | 0.00% | −82,853−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −57,957−100.0% | Sold out |