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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Design Therapeutics, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
100
+6 vs. Q2 2024
Shares held
32.0M
+2.24M (+7.5%) vs. Q2 2024
Total value
$172.3M
+$72.5M (+72.7%) vs. Q2 2024
New holders
15
29 more added
Sold out
9
34 more reduced

1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 100 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ3 2024: $172.3M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q2 2024.

Institutions holding DSGN in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Sr One Capital Management, LP6,526,476$35.1M7.04%00.0%Unchanged
Logos Global Management LP4,217,627$22.7M2.54%−814,874−16.2%Reduced
BlackRock, Inc.2,358,797$12.7M0.00%+2,358,797New
Frazier Life Sciences Management, L.P.1,892,547$10.2M0.41%+697,368+58.3%Added
Baker Bros. Advisors LP1,743,725$9.38M0.10%+48,431+2.9%Added
Point72 Asset Management, L.P.1,600,740$8.61M0.03%+609,939+61.6%Added
Tang Capital Management LLC1,480,975$7.97M0.57%00.0%Unchanged
Vanguard Group Inc1,394,024$7.50M0.00%+97,236+7.5%Added
Almitas Capital LLC1,323,667$7.12M2.52%+70,419+5.6%Added
FMR LLC828,665$4.46M0.00%+747,649+922.8%Added
Geode Capital Management, LLC758,550$4.08M0.00%+50,579+7.1%Added
State Street Corp690,826$3.72M0.00%−4,597−0.7%Reduced
D. E. Shaw & Co., Inc.582,858$3.14M0.00%+47,074+8.8%Added
Acadian Asset Management LLC583,160$3.13M0.01%00.0%Unchanged
Citadel Advisors LLC575,550$3.10M0.00%+270,920+88.9%Added
Morgan Stanley428,798$2.31M0.00%+39,361+10.1%Added
Assenagon Asset Management S.A.346,192$1.86M0.00%−1,602−0.5%Reduced
Prescott Group Capital Management, L.L.C.343,000$1.85M0.27%00.0%Unchanged
Northern Trust Corp336,774$1.81M0.00%−571−0.2%Reduced
Two Sigma Advisers, LP304,900$1.64M0.00%−95,200−23.8%Reduced
Two Sigma Investments, LP304,244$1.64M0.00%−98,471−24.5%Reduced
Jacobs Levy Equity Management, Inc280,271$1.51M0.01%−195,987−41.2%Reduced
Goldman Sachs Group Inc275,532$1.48M0.00%−328,173−54.4%Reduced
Renaissance Technologies LLC274,000$1.47M0.00%−110,075−28.7%Reduced
Charles Schwab Investment Management Inc257,432$1.38M0.00%+77,472+43.0%Added
Bridgeway Capital Management, LLC235,600$1.27M0.03%00.0%Unchanged
Nuveen Asset Management, LLC212,554$1.14M0.00%00.0%Unchanged
Millennium Management LLC207,257$1.12M0.00%−403,546−66.1%Reduced
Gsa Capital Partners LLP173,744$935.0K0.07%−36,209−17.2%Reduced
Dimensional Fund Advisors LP134,360$722.8K0.00%+53,407+66.0%Added
Bank of New York Mellon Corp99,125$533.3K0.00%−18,985−16.1%Reduced
Barclays PLC96,635$519.9K0.00%+24,602+34.2%Added
Squarepoint Ops LLC85,131$458.0K0.00%−4,824−5.4%Reduced
Walleye Capital LLC70,000$376.6K0.00%+9,788+16.3%Added
Prudential Financial Inc59,115$318.0K0.00%−4,100−6.5%Reduced
EcoR1 Capital, LLC53,834$289.6K0.01%+53,834New
Rhumbline Advisers50,567$272.0K0.00%−2,500−4.7%Reduced
Virtu Financial LLC46,356$249.0K0.01%+35,286+318.8%Added
Ameriprise Financial Inc43,245$232.7K0.00%−7,270−14.4%Reduced
Alliancebernstein L.P.42,090$226.4K0.00%00.0%Unchanged
JPMorgan Chase & Co40,687$218.9K0.00%+26,503+186.9%Added
Bank of America Corp36,811$198.0K0.00%+4,527+14.0%Added
Palumbo Wealth Management LLC36,774$197.8K0.08%+3,720+11.3%Added
PDT Partners, LLC36,099$194.2K0.02%+8,972+33.1%Added
American Century Companies Inc32,634$175.6K0.00%+11,301+53.0%Added
STRS Ohio32,600$175.4K0.00%00.0%Unchanged
HSBC Holdings PLC31,287$168.0K0.00%−13,183−29.6%Reduced
Deutsche Bank AG28,094$151.1K0.00%00.0%Unchanged
CI Private Wealth, LLC26,965$145.1K0.00%00.0%Unchanged
SpiderRock Advisors, LLC26,965$145.1K0.00%+26,965New
Jane Street Group, LLC24,003$129.1K0.00%−33,902−58.5%Reduced
Citigroup Inc23,145$124.5K0.00%+15,911+219.9%Added
MetLife Investment Management19,334$104.0K0.00%+19,334New
Tudor Investment Corp Et Al18,738$100.8K0.00%−1,127−5.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.17,197$92.5K0.00%+927+5.7%Added
Marshall Wace, LLP17,192$92.5K0.00%−7,088−29.2%Reduced
Corebridge Financial, Inc.16,789$90.3K0.00%−103−0.6%Reduced
Mariner, LLC16,128$86.7K0.00%−2,546−13.6%Reduced
Prelude Capital Management, LLC15,985$86.0K0.01%−16,971−51.5%Reduced
Caz Investments LP15,000$81.0K0.08%−25,000−62.5%Reduced
UBS Group AG14,880$80.1K0.00%+1,520+11.4%Added
Wells Fargo & Company14,415$77.6K0.00%+618+4.5%Added
Algert Global LLC14,378$77.4K0.00%+1,962+15.8%Added
Manufacturers Life Insurance Company, The13,221$71.1K0.00%+13,221New
SG Americas Securities, LLC12,289$66.0K0.00%+12,289New
Nisa Investment Advisors, LLC11,905$64.0K0.00%+50+0.4%Added
Paloma Partners Management Co11,902$64.0K0.00%+11,902New
Bleakley Financial Group, LLC11,591$62.4K0.00%−41−0.4%Reduced
Jump Financial, LLC11,000$59.2K0.00%−9,087−45.2%Reduced
AQR Capital Management LLC10,784$58.0K0.00%−299−2.7%Reduced
Price T Rowe Associates Inc10,284$56.0K0.00%00.0%Unchanged
AJOVista, LLC10,319$55.5K0.24%+10,319New
The PNC Financial Services Group, Inc.9,219$49.6K0.00%−473−4.9%Reduced
Public Employees Retirement System of Ohio8,272$44.5K0.00%−14,121−63.1%Reduced
Simplex Trading, LLC7,602$40.0K0.00%+6,307+487.0%Added
Royal Bank of Canada4,923$27.0K0.00%+1,970+66.7%Added
Russell Investments Group, Ltd.4,492$24.2K0.00%−3,752−45.5%Reduced
Federated Hermes, Inc.2,988$16.1K0.00%−1,212−28.9%Reduced
Ameritas Investment Partners, Inc.2,570$13.8K0.00%00.0%Unchanged
Legal & General Group Plc2,565$13.8K0.00%00.0%Unchanged
California State Teachers Retirement System2,275$12.2K0.00%00.0%Unchanged
New York State Common Retirement Fund2,026$10.9K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,705$9.17K0.00%−4,337−71.8%Reduced
Amalgamated Bank1,176$6.00K0.00%00.0%Unchanged
Group One Trading, L.P.1,000$5.38K0.00%−100−9.1%Reduced
Clearstead Advisors, LLC610$3.28K0.00%00.0%Unchanged
Private Wealth Management Group, LLC558$3.00K0.00%00.0%Unchanged
GAMMA Investing LLC417$2.24K0.00%+417New
Newbridge Financial Services Group, Inc.300$1.61K0.00%+300New
SRS Capital Advisors, Inc.244$1.31K0.00%00.0%Unchanged
Massmutual Trust Co FSB239$1.29K0.00%00.0%Unchanged
CWM, LLC124$1.00K0.00%+26+26.5%Added
Capital Performance Advisors LLP143$7690.00%+143New
Sterling Capital Management LLC102$5490.00%+102New
Principal Securities, Inc.74$3980.00%00.0%Unchanged
Point72 (DIFC) Ltd67$3620.00%+67New
Farther Finance Advisors, LLC19$1020.00%+19New
Advisor Group Holdings, Inc.10$540.00%+10New
Capital Advisors, Ltd. LLC12$00.00%00.0%Unchanged
Covestor Ltd20$00.00%−2−9.1%Reduced