Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Design Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 95
- −3 vs. Q3 2024
- Shares held
- 33.5M
- +1.47M (+4.6%) vs. Q3 2024
- Total value
- $206.5M
- +$34.3M (+19.9%) vs. Q3 2024
- New holders
- 15
- 34 more added
- Sold out
- 18
- 22 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sr One Capital Management, LP | 6,526,476 | $40.3M | 9.82% | 00.0% | Unchanged |
| Logos Global Management LP | 4,217,627 | $26.0M | 3.04% | 00.0% | Unchanged |
| BlackRock, Inc. | 2,579,599 | $15.9M | 0.00% | +220,802+9.4% | Added |
| Frazier Life Sciences Management, L.P. | 1,953,547 | $12.1M | 0.50% | +61,000+3.2% | Added |
| Point72 Asset Management, L.P. | 1,856,750 | $11.5M | 0.03% | +256,010+16.0% | Added |
| Baker Bros. Advisors LP | 1,743,725 | $10.8M | 0.11% | 00.0% | Unchanged |
| Tang Capital Management LLC | 1,480,975 | $9.14M | 0.60% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,430,745 | $8.83M | 0.00% | +36,721+2.6% | Added |
| Almitas Capital LLC | 1,323,667 | $8.17M | 1.79% | 00.0% | Unchanged |
| Citadel Advisors LLC | 958,793 | $5.92M | 0.01% | +383,243+66.6% | Added |
| FMR LLC | 951,882 | $5.87M | 0.00% | +123,217+14.9% | Added |
| Driehaus Capital Management LLC | 776,082 | $4.79M | 0.04% | +776,082 | New |
| Geode Capital Management, LLC | 761,640 | $4.70M | 0.00% | +3,090+0.4% | Added |
| State Street Corp | 723,319 | $4.46M | 0.00% | +32,493+4.7% | Added |
| Acadian Asset Management LLC | 567,604 | $3.50M | 0.01% | −15,556−2.7% | Reduced |
| MPM Oncology Impact Management LP | 559,547 | $3.45M | 0.49% | +559,547 | New |
| D. E. Shaw & Co., Inc. | 512,330 | $3.16M | 0.00% | −70,528−12.1% | Reduced |
| EcoR1 Capital, LLC | 426,683 | $2.63M | 0.11% | +372,849+692.6% | Added |
| Northern Trust Corp | 388,125 | $2.39M | 0.00% | +51,351+15.2% | Added |
| Morgan Stanley | 346,183 | $2.14M | 0.00% | −82,615−19.3% | Reduced |
| Goldman Sachs Group Inc | 297,129 | $1.83M | 0.00% | +21,597+7.8% | Added |
| Charles Schwab Investment Management Inc | 264,675 | $1.63M | 0.00% | +7,243+2.8% | Added |
| Renaissance Technologies LLC | 253,500 | $1.56M | 0.00% | −20,500−7.5% | Reduced |
| Two Sigma Advisers, LP | 233,900 | $1.44M | 0.00% | −71,000−23.3% | Reduced |
| Dimensional Fund Advisors LP | 215,265 | $1.33M | 0.00% | +80,905+60.2% | Added |
| Two Sigma Investments, LP | 203,931 | $1.26M | 0.00% | −100,313−33.0% | Reduced |
| Nuveen Asset Management, LLC | 158,004 | $974.9K | 0.00% | −54,550−25.7% | Reduced |
| Walleye Capital LLC | 141,127 | $870.8K | 0.01% | +71,127+101.6% | Added |
| Bridgeway Capital Management, LLC | 128,400 | $792.2K | 0.02% | −107,200−45.5% | Reduced |
| Gsa Capital Partners LLP | 118,328 | $730.0K | 0.05% | −55,416−31.9% | Reduced |
| Barclays PLC | 103,571 | $639.0K | 0.00% | +6,936+7.2% | Added |
| Bank of New York Mellon Corp | 95,348 | $588.3K | 0.00% | −3,777−3.8% | Reduced |
| JPMorgan Chase & Co | 89,215 | $550.5K | 0.00% | +48,528+119.3% | Added |
| UBS Group AG | 66,587 | $410.8K | 0.00% | +51,707+347.5% | Added |
| Assenagon Asset Management S.A. | 56,617 | $349.3K | 0.00% | −289,575−83.6% | Reduced |
| Prudential Financial Inc | 56,315 | $347.5K | 0.00% | −2,800−4.7% | Reduced |
| Palumbo Wealth Management LLC | 54,696 | $337.5K | 0.13% | +17,922+48.7% | Added |
| Rhumbline Advisers | 52,932 | $326.6K | 0.00% | +2,365+4.7% | Added |
| XTX Topco Ltd | 48,424 | $298.8K | 0.03% | +48,424 | New |
| Squarepoint Ops LLC | 48,186 | $297.3K | 0.00% | −36,945−43.4% | Reduced |
| Alliancebernstein L.P. | 42,090 | $259.7K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 40,289 | $248.6K | 0.00% | +40,289 | New |
| American Century Companies Inc | 39,115 | $241.3K | 0.00% | +6,481+19.9% | Added |
| Susquehanna International Group, LLP | 37,312 | $230.2K | 0.00% | +37,312 | New |
| PDT Partners, LLC | 36,099 | $222.7K | 0.02% | 00.0% | Unchanged |
| Bank of America Corp | 35,160 | $216.9K | 0.00% | −1,651−4.5% | Reduced |
| STRS Ohio | 32,600 | $201.1K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 29,855 | $184.2K | 0.00% | +19,071+176.8% | Added |
| Deutsche Bank AG | 28,094 | $173.3K | 0.00% | 00.0% | Unchanged |
| CI Private Wealth, LLC | 26,965 | $166.4K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 24,476 | $151.0K | 0.00% | +1,331+5.8% | Added |
| MetLife Investment Management | 19,334 | $119.3K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 18,428 | $113.7K | 0.00% | +4,013+27.8% | Added |
| Jacobs Levy Equity Management, Inc | 18,261 | $112.7K | 0.00% | −262,010−93.5% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 17,957 | $110.8K | 0.00% | +760+4.4% | Added |
| Intech Investment Management LLC | 17,665 | $109.0K | 0.00% | +17,665 | New |
| Mariner, LLC | 16,257 | $100.3K | 0.00% | +129+0.8% | Added |
| Algert Global LLC | 16,238 | $100.2K | 0.00% | +1,860+12.9% | Added |
| Corebridge Financial, Inc. | 15,610 | $96.3K | 0.00% | −1,179−7.0% | Reduced |
| Caz Investments LP | 15,000 | $93.0K | 0.13% | 00.0% | Unchanged |
| Kennedy Capital Management, Inc. | 14,266 | $88.0K | 0.00% | +14,266 | New |
| SG Americas Securities, LLC | 13,667 | $84.0K | 0.00% | +1,378+11.2% | Added |
| Bleakley Financial Group, LLC | 13,266 | $81.9K | 0.00% | +1,675+14.5% | Added |
| Manufacturers Life Insurance Company, The | 13,070 | $80.6K | 0.00% | −151−1.1% | Reduced |
| Price T Rowe Associates Inc | 12,451 | $77.0K | 0.00% | +2,167+21.1% | Added |
| China Universal Asset Management Co., Ltd. | 12,006 | $74.1K | 0.01% | +12,006 | New |
| Nisa Investment Advisors, LLC | 11,855 | $73.1K | 0.00% | −50−0.4% | Reduced |
| Invesco Ltd. | 11,583 | $71.5K | 0.00% | +11,583 | New |
| ProShare Advisors LLC | 11,525 | $71.1K | 0.00% | +11,525 | New |
| The PNC Financial Services Group, Inc. | 9,219 | $56.9K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 6,598 | $40.7K | 0.00% | +6,598 | New |
| Simplex Trading, LLC | 5,168 | $31.0K | 0.00% | −2,434−32.0% | Reduced |
| Royal Bank of Canada | 4,067 | $25.0K | 0.00% | −856−17.4% | Reduced |
| Russell Investments Group, Ltd. | 3,059 | $18.9K | 0.00% | −1,433−31.9% | Reduced |
| Ameritas Investment Partners, Inc. | 2,570 | $15.9K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 2,565 | $15.8K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 2,275 | $14.0K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 2,026 | $12.5K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 1,887 | $11.8K | 0.00% | +1,887 | New |
| Tower Research Capital LLC (TRC) | 1,761 | $10.9K | 0.00% | +56+3.3% | Added |
| GF Fund Management Co. Ltd. | 1,189 | $7.34K | 0.00% | +1,189 | New |
| Amalgamated Bank | 1,176 | $7.00K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 1,070 | $6.60K | 0.00% | +653+156.6% | Added |
| Sterling Capital Management LLC | 1,005 | $6.20K | 0.00% | +903+885.3% | Added |
| Venturi Wealth Management, LLC | 753 | $4.65K | 0.00% | +753 | New |
| CoreCap Advisors, LLC | 712 | $4.39K | 0.00% | +712 | New |
| Clearstead Advisors, LLC | 610 | $3.76K | 0.00% | 00.0% | Unchanged |
| Private Wealth Management Group, LLC | 558 | $3.44K | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 239 | $1.48K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 141 | $1.00K | 0.00% | +17+13.7% | Added |
| SRS Capital Advisors, Inc. | 143 | $883 | 0.00% | −101−41.4% | Reduced |
| Principal Securities, Inc. | 74 | $457 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 73 | $450 | 0.00% | +63+630.0% | Added |
| Farther Finance Advisors, LLC | 19 | $117 | 0.00% | 00.0% | Unchanged |
| Capital Advisors, Ltd. LLC | 12 | $0 | 0.00% | 00.0% | Unchanged |
| Prescott Group Capital Management, L.L.C. | 0 | $0 | 0.00% | −343,000−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −207,257−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −46,356−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −43,245−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −31,287−100.0% | Sold out |