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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Design Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
95
−3 vs. Q3 2024
Shares held
33.5M
+1.47M (+4.6%) vs. Q3 2024
Total value
$206.5M
+$34.3M (+19.9%) vs. Q3 2024
New holders
15
34 more added
Sold out
18
22 more reduced

2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 95 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ4 2024: $206.5M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q3 2024.

Institutions holding DSGN in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC12$00.00%00.0%Unchanged
Farther Finance Advisors, LLC19$1170.00%00.0%Unchanged
Advisor Group Holdings, Inc.73$4500.00%+63+630.0%Added
Principal Securities, Inc.74$4570.00%00.0%Unchanged
SRS Capital Advisors, Inc.143$8830.00%−101−41.4%Reduced
CWM, LLC141$1.00K0.00%+17+13.7%Added
Massmutual Trust Co FSB239$1.48K0.00%00.0%Unchanged
Private Wealth Management Group, LLC558$3.44K0.00%00.0%Unchanged
Clearstead Advisors, LLC610$3.76K0.00%00.0%Unchanged
CoreCap Advisors, LLC712$4.39K0.00%+712New
Venturi Wealth Management, LLC753$4.65K0.00%+753New
Sterling Capital Management LLC1,005$6.20K0.00%+903+885.3%Added
GAMMA Investing LLC1,070$6.60K0.00%+653+156.6%Added
Amalgamated Bank1,176$7.00K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,189$7.34K0.00%+1,189New
Tower Research Capital LLC (TRC)1,761$10.9K0.00%+56+3.3%Added
Mirae Asset Global Investments Co., Ltd.1,887$11.8K0.00%+1,887New
New York State Common Retirement Fund2,026$12.5K0.00%00.0%Unchanged
California State Teachers Retirement System2,275$14.0K0.00%00.0%Unchanged
Legal & General Group Plc2,565$15.8K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.2,570$15.9K0.00%00.0%Unchanged
Russell Investments Group, Ltd.3,059$18.9K0.00%−1,433−31.9%Reduced
Royal Bank of Canada4,067$25.0K0.00%−856−17.4%Reduced
Simplex Trading, LLC5,168$31.0K0.00%−2,434−32.0%Reduced
Police & Firemen's Retirement System of New Jersey6,598$40.7K0.00%+6,598New
The PNC Financial Services Group, Inc.9,219$56.9K0.00%00.0%Unchanged
ProShare Advisors LLC11,525$71.1K0.00%+11,525New
Invesco Ltd.11,583$71.5K0.00%+11,583New
Nisa Investment Advisors, LLC11,855$73.1K0.00%−50−0.4%Reduced
China Universal Asset Management Co., Ltd.12,006$74.1K0.01%+12,006New
Price T Rowe Associates Inc12,451$77.0K0.00%+2,167+21.1%Added
Manufacturers Life Insurance Company, The13,070$80.6K0.00%−151−1.1%Reduced
Bleakley Financial Group, LLC13,266$81.9K0.00%+1,675+14.5%Added
SG Americas Securities, LLC13,667$84.0K0.00%+1,378+11.2%Added
Kennedy Capital Management, Inc.14,266$88.0K0.00%+14,266New
Caz Investments LP15,000$93.0K0.13%00.0%Unchanged
Corebridge Financial, Inc.15,610$96.3K0.00%−1,179−7.0%Reduced
Algert Global LLC16,238$100.2K0.00%+1,860+12.9%Added
Mariner, LLC16,257$100.3K0.00%+129+0.8%Added
Intech Investment Management LLC17,665$109.0K0.00%+17,665New
Mirae Asset Global ETFs Holdings Ltd.17,957$110.8K0.00%+760+4.4%Added
Jacobs Levy Equity Management, Inc18,261$112.7K0.00%−262,010−93.5%Reduced
Wells Fargo & Company18,428$113.7K0.00%+4,013+27.8%Added
MetLife Investment Management19,334$119.3K0.00%00.0%Unchanged
Citigroup Inc24,476$151.0K0.00%+1,331+5.8%Added
CI Private Wealth, LLC26,965$166.4K0.00%00.0%Unchanged
Deutsche Bank AG28,094$173.3K0.00%00.0%Unchanged
AQR Capital Management LLC29,855$184.2K0.00%+19,071+176.8%Added
STRS Ohio32,600$201.1K0.00%00.0%Unchanged
Bank of America Corp35,160$216.9K0.00%−1,651−4.5%Reduced
PDT Partners, LLC36,099$222.7K0.02%00.0%Unchanged
Susquehanna International Group, LLP37,312$230.2K0.00%+37,312New
American Century Companies Inc39,115$241.3K0.00%+6,481+19.9%Added
BNP Paribas Arbitrage, SA40,289$248.6K0.00%+40,289New
Alliancebernstein L.P.42,090$259.7K0.00%00.0%Unchanged
Squarepoint Ops LLC48,186$297.3K0.00%−36,945−43.4%Reduced
XTX Topco Ltd48,424$298.8K0.03%+48,424New
Rhumbline Advisers52,932$326.6K0.00%+2,365+4.7%Added
Palumbo Wealth Management LLC54,696$337.5K0.13%+17,922+48.7%Added
Prudential Financial Inc56,315$347.5K0.00%−2,800−4.7%Reduced
Assenagon Asset Management S.A.56,617$349.3K0.00%−289,575−83.6%Reduced
UBS Group AG66,587$410.8K0.00%+51,707+347.5%Added
JPMorgan Chase & Co89,215$550.5K0.00%+48,528+119.3%Added
Bank of New York Mellon Corp95,348$588.3K0.00%−3,777−3.8%Reduced
Barclays PLC103,571$639.0K0.00%+6,936+7.2%Added
Gsa Capital Partners LLP118,328$730.0K0.05%−55,416−31.9%Reduced
Bridgeway Capital Management, LLC128,400$792.2K0.02%−107,200−45.5%Reduced
Walleye Capital LLC141,127$870.8K0.01%+71,127+101.6%Added
Nuveen Asset Management, LLC158,004$974.9K0.00%−54,550−25.7%Reduced
Two Sigma Investments, LP203,931$1.26M0.00%−100,313−33.0%Reduced
Dimensional Fund Advisors LP215,265$1.33M0.00%+80,905+60.2%Added
Two Sigma Advisers, LP233,900$1.44M0.00%−71,000−23.3%Reduced
Renaissance Technologies LLC253,500$1.56M0.00%−20,500−7.5%Reduced
Charles Schwab Investment Management Inc264,675$1.63M0.00%+7,243+2.8%Added
Goldman Sachs Group Inc297,129$1.83M0.00%+21,597+7.8%Added
Morgan Stanley346,183$2.14M0.00%−82,615−19.3%Reduced
Northern Trust Corp388,125$2.39M0.00%+51,351+15.2%Added
EcoR1 Capital, LLC426,683$2.63M0.11%+372,849+692.6%Added
D. E. Shaw & Co., Inc.512,330$3.16M0.00%−70,528−12.1%Reduced
MPM Oncology Impact Management LP559,547$3.45M0.49%+559,547New
Acadian Asset Management LLC567,604$3.50M0.01%−15,556−2.7%Reduced
State Street Corp723,319$4.46M0.00%+32,493+4.7%Added
Geode Capital Management, LLC761,640$4.70M0.00%+3,090+0.4%Added
Driehaus Capital Management LLC776,082$4.79M0.04%+776,082New
FMR LLC951,882$5.87M0.00%+123,217+14.9%Added
Citadel Advisors LLC958,793$5.92M0.01%+383,243+66.6%Added
Almitas Capital LLC1,323,667$8.17M1.79%00.0%Unchanged
Vanguard Group Inc1,430,745$8.83M0.00%+36,721+2.6%Added
Tang Capital Management LLC1,480,975$9.14M0.60%00.0%Unchanged
Baker Bros. Advisors LP1,743,725$10.8M0.11%00.0%Unchanged
Point72 Asset Management, L.P.1,856,750$11.5M0.03%+256,010+16.0%Added
Frazier Life Sciences Management, L.P.1,953,547$12.1M0.50%+61,000+3.2%Added
BlackRock, Inc.2,579,599$15.9M0.00%+220,802+9.4%Added
Logos Global Management LP4,217,627$26.0M3.04%00.0%Unchanged
Sr One Capital Management, LP6,526,476$40.3M9.82%00.0%Unchanged
Prescott Group Capital Management, L.L.C.0$00.00%−343,000−100.0%Sold out
Millennium Management LLC0$00.00%−207,257−100.0%Sold out
Virtu Financial LLC0$00.00%−46,356−100.0%Sold out
Ameriprise Financial Inc0$00.00%−43,245−100.0%Sold out
HSBC Holdings PLC0$00.00%−31,287−100.0%Sold out