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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q2 2023

Institutional positions in Design Therapeutics, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
97
+1 vs. Q1 2023
Shares held
38.8M
+94.7K (+0.2%) vs. Q1 2023
Total value
$244.4M
+$21.1M (+9.5%) vs. Q1 2023
New holders
10
30 more added
Sold out
9
43 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 97 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ2 2023: $244.4M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q1 2023.

Institutions holding DSGN in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Sr One Capital Management, LP6,526,476$41.1M17.73%00.0%Unchanged
Cormorant Asset Management, LP5,150,000$32.4M1.85%00.0%Unchanged
Avoro Capital Advisors LLC3,500,000$22.1M0.30%00.0%Unchanged
BlackRock Inc.2,994,051$18.9M0.00%−191,840−6.0%Reduced
Ra Capital Management, L.P.2,971,231$18.7M0.35%00.0%Unchanged
Citadel Advisors LLC2,856,106$18.0M0.02%−9,061−0.3%Reduced
Logos Global Management LP2,797,501$17.6M2.43%00.0%Unchanged
RTW Investments, LP1,563,031$9.85M0.19%+1,563,031New
Vanguard Group Inc983,274$6.19M0.00%−299,769−23.4%Reduced
Janus Henderson Group PLC829,425$5.23M0.00%−14,293−1.7%Reduced
Principal Financial Group Inc728,221$4.59M0.00%+8,284+1.2%Added
FMR LLC637,770$4.02M0.00%−320,133−33.4%Reduced
Geode Capital Management, LLC636,845$4.01M0.00%+3,837+0.6%Added
State Street Corp586,035$3.69M0.00%−125,493−17.6%Reduced
Wellington Management Group LLP502,375$3.16M0.00%−47,957−8.7%Reduced
Baker Bros. Advisors LP500,000$3.15M0.02%−126,884−20.2%Reduced
Rock Springs Capital Management LP460,391$2.90M0.07%00.0%Unchanged
Goldman Sachs Group Inc447,416$2.82M0.00%+146,792+48.8%Added
Northern Trust Corp324,738$2.05M0.00%+48,970+17.8%Added
Assenagon Asset Management S.A.301,688$1.90M0.01%+133,473+79.3%Added
Millennium Management LLC279,879$1.76M0.00%−510,334−64.6%Reduced
ExodusPoint Capital Management, LP265,384$1.67M0.02%+109,246+70.0%Added
Gsa Capital Partners LLP238,200$1.50M0.15%+140,300+143.3%Added
Charles Schwab Investment Management Inc228,806$1.44M0.00%−1,541−0.7%Reduced
Morgan Stanley190,768$1.20M0.00%+121,391+175.0%Added
Candriam Luxembourg S.C.A.185,000$1.17M0.01%+185,000New
Nuveen Asset Management, LLC154,539$973.6K0.00%+38,739+33.5%Added
D. E. Shaw & Co., Inc.135,280$852.3K0.00%+23,982+21.5%Added
Bank of New York Mellon Corp122,665$772.8K0.00%−1,388−1.1%Reduced
Two Sigma Investments, LP115,782$729.4K0.00%−63,314−35.4%Reduced
Marshall Wace, LLP112,922$711.4K0.00%−67,997−37.6%Reduced
Bank of Montreal99,240$629.2K0.00%+99,240New
HRT Financial LP95,264$600.0K0.01%−29,699−23.8%Reduced
Renaissance Technologies LLC95,108$599.0K0.00%−6,643−6.5%Reduced
State of Wisconsin Investment Board84,000$529.2K0.00%+40,900+94.9%Added
Two Sigma Advisers, LP79,000$497.7K0.00%+32,300+69.2%Added
Bank of America Corp77,878$490.6K0.00%+21,635+38.5%Added
Cubist Systematic Strategies, LLC66,686$420.1K0.00%−111,598−62.6%Reduced
Dimensional Fund Advisors LP59,635$374.9K0.00%−16,850−22.0%Reduced
Susquehanna International Group, LLP56,794$357.8K0.00%−247,275−81.3%Reduced
JPMorgan Chase & Co51,983$327.5K0.00%+26,027+100.3%Added
Rhumbline Advisers51,590$325.0K0.00%−98−0.2%Reduced
PDT Partners, LLC47,512$299.3K0.04%−12,457−20.8%Reduced
Trexquant Investment LP46,524$293.1K0.01%−4,315−8.5%Reduced
Squarepoint Ops LLC41,590$262.0K0.00%−67,624−61.9%Reduced
Alliancebernstein L.P.41,400$260.8K0.00%+10,200+32.7%Added
Jane Street Group, LLC33,334$210.0K0.00%−169,390−83.6%Reduced
Prudential Financial Inc26,215$165.2K0.00%+26,215New
UBS Group AG24,162$152.2K0.00%+23,956+11,629.1%Added
MetLife Investment Management22,045$138.9K0.00%00.0%Unchanged
Tudor Investment Corp Et Al20,561$129.5K0.00%−7,078−25.6%Reduced
Virtus ETF Advisers LLC20,137$126.9K0.08%+8,741+76.7%Added
Algert Global LLC19,430$122.4K0.01%+19,430New
Balyasny Asset Management LLC18,499$116.5K0.00%+18,499New
Corton Capital Inc.17,323$109.1K0.05%+17,323New
Jacobs Levy Equity Management, Inc16,100$101.4K0.00%+16,100New
Deutsche Bank AG15,901$100.2K0.00%−8,955−36.0%Reduced
Barclays PLC15,820$99.7K0.00%−1,397−8.1%Reduced
American International Group, Inc.15,773$99.4K0.00%−580−3.5%Reduced
Mirae Asset Global Investments Co., Ltd.15,398$97.0K0.00%−114−0.7%Reduced
Manufacturers Life Insurance Company, The15,173$95.6K0.00%+1,546+11.3%Added
Schonfeld Strategic Advisors LLC14,100$88.8K0.00%+700+5.2%Added
Voya Investment Management LLC14,090$88.8K0.00%+928+7.1%Added
State Board of Administration of Florida Retirement System12,630$79.6K0.00%00.0%Unchanged
Wells Fargo & Company12,463$78.5K0.00%+6,469+107.9%Added
Jump Financial, LLC12,139$76.5K0.00%−46,661−79.4%Reduced
Verition Fund Management LLC11,786$74.3K0.00%−32,394−73.3%Reduced
Walleye Capital LLC11,138$70.2K0.00%+11,138New
California State Teachers Retirement System10,901$68.7K0.00%−1,697−13.5%Reduced
XTX Topco Ltd10,799$68.0K0.01%+10,799New
Citigroup Inc10,716$67.5K0.00%+7,309+214.5%Added
Point72 Middle East FZE9,085$57.2K0.00%−279−3.0%Reduced
Point72 Asset Management, L.P.5,349$33.7K0.00%−4,781−47.2%Reduced
Tower Research Capital LLC (TRC)5,300$33.4K0.00%+3,201+152.5%Added
Quantbot Technologies LP4,705$29.6K0.00%−6,148−56.6%Reduced
Royal Bank of Canada3,574$23.0K0.00%+1,508+73.0%Added
Amalgamated Bank3,280$21.0K0.00%−226−6.4%Reduced
Legal & General Group Plc3,127$19.7K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.2,570$16.2K0.00%00.0%Unchanged
Metropolitan Life Insurance Co2,016$12.7K0.00%00.0%Unchanged
New York State Common Retirement Fund1,994$12.6K0.00%−15,640−88.7%Reduced
Assetmark, Inc1,874$11.8K0.00%+216+13.0%Added
Russell Investments Group, Ltd.1,394$8.78K0.00%+402+40.5%Added
Signaturefd, LLC1,211$7.63K0.00%−138−10.2%Reduced
China Universal Asset Management Co., Ltd.733$4.62K0.00%−25−3.3%Reduced
Clearstead Advisors, LLC610$3.84K0.00%00.0%Unchanged
Lindbrook Capital, LLC607$3.82K0.00%−928−60.5%Reduced
Federated Hermes, Inc.508$3.20K0.00%−133−20.7%Reduced
US Bancorp438$2.76K0.00%−41−8.6%Reduced
Quadrant Capital Group LLC362$2.28K0.00%−254−41.2%Reduced
Allworth Financial LP336$2.12K0.00%+300+833.3%Added
Simplex Trading, LLC382$2.00K0.00%−155−28.9%Reduced
Advisor Group Holdings, Inc.232$1.46K0.00%+29+14.3%Added
Daiwa Securities Group Inc.162$1.00K0.00%00.0%Unchanged
Parallel Advisors, LLC102$6430.00%+52+104.0%Added
Zurcher Kantonalbank (Zurich Cantonalbank)1$60.00%00.0%Unchanged
Covestor Ltd20$00.00%+12+150.0%Added
Ergoteles LLC0$00.00%−177,337−100.0%Sold out
Centiva Capital, LP0$00.00%−23,572−100.0%Sold out
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.0$00.00%−19,306−100.0%Sold out