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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Design Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
60
+8 vs. Q3 2021
Shares held
36.2M
+7.89M (+27.9%) vs. Q3 2021
Total value
$773.1M
+$358.3M (+86.4%) vs. Q3 2021
New holders
13
29 more added
Sold out
5
5 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 60 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ4 2021: $773.1M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q3 2021.

Institutions holding DSGN in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Sr One Capital Management, LP5,626,476$120.5M68.08%+5,626,476New
Cormorant Asset Management, LP5,440,453$116.5M6.93%+75,603+1.4%Added
Logos Global Management LP2,772,501$59.4M6.12%00.0%Unchanged
Citadel Advisors LLC2,534,702$54.3M0.06%−37,828−1.5%Reduced
BlackRock Inc.2,215,624$47.4M0.00%+902,960+68.8%Added
Ra Capital Management, L.P.2,186,636$46.8M0.83%00.0%Unchanged
EcoR1 Capital, LLC2,152,997$46.1M1.48%+289,899+15.6%Added
Vanguard Group Inc1,870,502$40.0M0.00%+782,301+71.9%Added
Avoro Capital Advisors LLC1,636,100$35.0M0.60%+167,782+11.4%Added
Baker Bros. Advisors LP1,436,636$30.8M0.15%00.0%Unchanged
FMR LLC1,000,000$21.4M0.00%00.0%Unchanged
Janus Henderson Group PLC936,767$19.1M0.01%+1080.0%Added
Wellington Management Group LLP855,538$18.3M0.00%−100,050−10.5%Reduced
Price T Rowe Associates Inc787,665$16.9M0.00%−661,303−45.6%Reduced
Vivo Capital, LLC530,991$11.4M0.69%00.0%Unchanged
Principal Financial Group Inc522,454$11.2M0.01%+301,944+136.9%Added
Artal Group S.A.400,000$8.56M0.25%00.0%Unchanged
Eventide Asset Management, LLC400,000$8.56M0.11%00.0%Unchanged
Geode Capital Management, LLC351,441$7.52M0.00%+93,409+36.2%Added
State Street Corp342,261$7.33M0.00%+130,653+61.7%Added
Rock Springs Capital Management LP335,247$7.18M0.17%+1,197+0.4%Added
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)280,991$6.02M0.09%00.0%Unchanged
Northern Trust Corp212,015$4.54M0.00%+89,183+72.6%Added
Norges Bank200,000$4.28M0.00%00.0%Unchanged
Adage Capital Partners GP, L.L.C.165,000$3.53M0.01%00.0%Unchanged
Ghost Tree Capital, LLC135,000$2.89M1.11%+135,000New
Charles Schwab Investment Management Inc118,556$2.54M0.00%+28,035+31.0%Added
Goldman Sachs Group Inc67,838$1.45M0.00%+12,704+23.0%Added
Bank of New York Mellon Corp67,108$1.44M0.00%+30,632+84.0%Added
TD Asset Management Inc65,718$1.41M0.00%00.0%Unchanged
Tekla Capital Management LLC65,351$1.40M0.05%+65,351New
Nuveen Asset Management, LLC73,113$1.32M0.00%+30,068+69.9%Added
Bank of America Corp54,937$1.18M0.00%+23,307+73.7%Added
Ensign Peak Advisors, Inc50,000$1.07M0.00%00.0%Unchanged
Citigroup Inc28,199$604.0K0.00%+3,391+13.7%Added
Rhumbline Advisers23,289$499.0K0.00%+12,700+119.9%Added
Qube Research & Technologies Ltd23,052$494.0K0.00%+23,052New
State of Wisconsin Investment Board17,400$373.0K0.00%00.0%Unchanged
Deutsche Bank AG17,018$364.0K0.00%+9,003+112.3%Added
JPMorgan Chase & Co15,735$337.0K0.00%+7,598+93.4%Added
DekaBank Deutsche Girozentrale17,000$336.0K0.00%+17,000New
California State Teachers Retirement System14,521$311.0K0.00%+7,279+100.5%Added
American International Group, Inc.14,132$303.0K0.00%+6,509+85.4%Added
ProShare Advisors LLC13,596$291.0K0.00%+13,596New
Morgan Stanley13,304$285.0K0.00%+5,900+79.7%Added
Manufacturers Life Insurance Company, The13,126$280.0K0.00%+13,126New
New York State Common Retirement Fund12,957$277.0K0.00%+1,219+10.4%Added
MetLife Investment Management10,864$232.6K0.00%+10,864New
Wells Fargo & Company9,943$213.0K0.00%+9,943New
Invesco Ltd.9,622$206.0K0.00%+9,622New
Metropolitan Life Insurance Co8,048$172.3K0.00%+8,048New
Royal Bank of Canada5,901$126.0K0.00%+4,311+271.1%Added
SG Americas Securities, LLC5,639$121.0K0.00%+5,639New
Legal & General Group Plc2,463$53.0K0.00%+1,187+93.0%Added
Ameritas Investment Partners, Inc.2,055$44.0K0.00%+998+94.4%Added
Tower Research Capital LLC (TRC)1,271$27.0K0.00%+825+185.0%Added
Advisor Group Holdings, Inc.205$5.00K0.00%+109+113.5%Added
Daiwa Securities Group Inc.162$3.00K0.00%+162New
State of Wyoming77$2.00K0.00%−4−4.9%Reduced
UBS Group AG35$1.00K0.00%−1,099−96.9%Reduced
Credit Suisse AG0$00.00%−235,938−100.0%Sold out
Octagon Capital Advisors LP0$00.00%−14,926−100.0%Sold out
Millennium Management LLC0$00.00%−14,169−100.0%Sold out
Piper Sandler & Co.0$00.00%−2,500−100.0%Sold out
STRS Ohio0$00.00%−2,000−100.0%Sold out