Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Design Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 98
- +4 vs. Q4 2024
- Shares held
- 34.5M
- +1.16M (+3.5%) vs. Q4 2024
- Total value
- $133.0M
- −$72.5M (−35.3%) vs. Q4 2024
- New holders
- 14
- 28 more added
- Sold out
- 10
- 36 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sr One Capital Management, LP | 6,526,476 | $25.2M | 6.47% | 00.0% | Unchanged |
| Logos Global Management LP | 4,217,627 | $16.3M | 2.89% | 00.0% | Unchanged |
| BlackRock, Inc. | 2,479,963 | $9.57M | 0.00% | −99,636−3.9% | Reduced |
| Frazier Life Sciences Management, L.P. | 1,953,547 | $7.54M | 0.34% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 1,817,858 | $7.02M | 0.02% | −38,892−2.1% | Reduced |
| Baker Bros. Advisors LP | 1,743,725 | $6.73M | 0.07% | 00.0% | Unchanged |
| Tang Capital Management LLC | 1,680,975 | $6.49M | 0.36% | +200,000+13.5% | Added |
| Almitas Capital LLC | 1,452,896 | $5.61M | 1.86% | +129,229+9.8% | Added |
| Vanguard Group Inc | 1,427,467 | $5.51M | 0.00% | −3,278−0.2% | Reduced |
| Citadel Advisors LLC | 963,460 | $3.72M | 0.00% | +4,667+0.5% | Added |
| FMR LLC | 948,050 | $3.66M | 0.00% | −3,832−0.4% | Reduced |
| Driehaus Capital Management LLC | 913,399 | $3.53M | 0.03% | +137,317+17.7% | Added |
| Kynam Capital Management, LP | 904,017 | $3.49M | 0.30% | +904,017 | New |
| Geode Capital Management, LLC | 775,497 | $2.99M | 0.00% | +13,857+1.8% | Added |
| State Street Corp | 714,074 | $2.76M | 0.00% | −9,245−1.3% | Reduced |
| Woodline Partners LP | 645,694 | $2.49M | 0.02% | +645,694 | New |
| Acadian Asset Management LLC | 630,953 | $2.43M | 0.01% | +63,349+11.2% | Added |
| MPM Oncology Impact Management LP | 562,943 | $2.17M | 0.37% | +3,396+0.6% | Added |
| D. E. Shaw & Co., Inc. | 395,251 | $1.53M | 0.00% | −117,079−22.9% | Reduced |
| Northern Trust Corp | 373,653 | $1.44M | 0.00% | −14,472−3.7% | Reduced |
| Dimensional Fund Advisors LP | 288,602 | $1.11M | 0.00% | +73,337+34.1% | Added |
| Goldman Sachs Group Inc | 266,016 | $1.03M | 0.00% | −31,113−10.5% | Reduced |
| Renaissance Technologies LLC | 265,000 | $1.02M | 0.00% | +11,500+4.5% | Added |
| Charles Schwab Investment Management Inc | 258,375 | $997.3K | 0.00% | −6,300−2.4% | Reduced |
| Morgan Stanley | 247,878 | $956.8K | 0.00% | −98,305−28.4% | Reduced |
| Nuveen, LLC | 147,228 | $568.3K | 0.00% | +147,228 | New |
| Two Sigma Advisers, LP | 146,700 | $566.3K | 0.00% | −87,200−37.3% | Reduced |
| Wellington Management Group LLP | 141,519 | $546.3K | 0.00% | +141,519 | New |
| Two Sigma Investments, LP | 128,747 | $497.0K | 0.00% | −75,184−36.9% | Reduced |
| Bridgeway Capital Management, LLC | 113,800 | $439.3K | 0.01% | −14,600−11.4% | Reduced |
| Bank of New York Mellon Corp | 95,348 | $368.0K | 0.00% | 00.0% | Unchanged |
| Millennium Management LLC | 87,988 | $339.6K | 0.00% | +87,988 | New |
| Barclays PLC | 84,006 | $324.3K | 0.00% | −19,565−18.9% | Reduced |
| Gsa Capital Partners LLP | 72,149 | $278.0K | 0.03% | −46,179−39.0% | Reduced |
| Lynx1 Capital Management LP | 65,954 | $254.6K | 0.09% | +65,954 | New |
| Palumbo Wealth Management LLC | 58,278 | $225.0K | 0.08% | +3,582+6.5% | Added |
| Prudential Financial Inc | 56,405 | $217.7K | 0.00% | +90+0.2% | Added |
| BNP Paribas Arbitrage, SA | 52,872 | $204.1K | 0.00% | +12,583+31.2% | Added |
| Rhumbline Advisers | 46,369 | $179.0K | 0.00% | −6,563−12.4% | Reduced |
| American Century Companies Inc | 44,415 | $171.4K | 0.00% | +5,300+13.5% | Added |
| Susquehanna International Group, LLP | 43,223 | $166.8K | 0.00% | +5,911+15.8% | Added |
| Alliancebernstein L.P. | 42,090 | $162.5K | 0.00% | 00.0% | Unchanged |
| Assenagon Asset Management S.A. | 36,917 | $142.5K | 0.00% | −19,700−34.8% | Reduced |
| UBS Group AG | 32,819 | $126.7K | 0.00% | −33,768−50.7% | Reduced |
| AQR Capital Management LLC | 31,740 | $122.5K | 0.00% | +1,885+6.3% | Added |
| Deutsche Bank AG | 28,129 | $108.6K | 0.00% | +35+0.1% | Added |
| CI Private Wealth, LLC | 26,965 | $104.1K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 22,879 | $88.3K | 0.00% | −1,597−6.5% | Reduced |
| STRS Ohio | 22,600 | $87.2K | 0.00% | −10,000−30.7% | Reduced |
| Bank of America Corp | 22,166 | $85.6K | 0.00% | −12,994−37.0% | Reduced |
| State of Wisconsin Investment Board | 21,962 | $84.8K | 0.00% | +21,962 | New |
| Intech Investment Management LLC | 20,550 | $79.3K | 0.00% | +2,885+16.3% | Added |
| JPMorgan Chase & Co | 19,277 | $74.4K | 0.00% | −69,938−78.4% | Reduced |
| MetLife Investment Management | 18,962 | $73.2K | 0.00% | −372−1.9% | Reduced |
| Wells Fargo & Company | 18,846 | $72.7K | 0.00% | +418+2.3% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 18,737 | $72.3K | 0.00% | +780+4.3% | Added |
| Jane Street Group, LLC | 18,125 | $70.0K | 0.00% | +18,125 | New |
| Jacobs Levy Equity Management, Inc | 17,482 | $67.5K | 0.00% | −779−4.3% | Reduced |
| Mariner, LLC | 15,471 | $59.7K | 0.00% | −786−4.8% | Reduced |
| Corebridge Financial, Inc. | 15,383 | $59.4K | 0.00% | −227−1.5% | Reduced |
| Caz Investments LP | 15,000 | $58.0K | 0.42% | 00.0% | Unchanged |
| Kennedy Capital Management, Inc. | 14,383 | $55.5K | 0.00% | +117+0.8% | Added |
| Velan Capital Investment Management LP | 14,000 | $54.0K | 0.06% | +14,000 | New |
| Price T Rowe Associates Inc | 13,069 | $51.0K | 0.00% | +618+5.0% | Added |
| Manufacturers Life Insurance Company, The | 12,957 | $50.0K | 0.00% | −113−0.9% | Reduced |
| SG Americas Securities, LLC | 12,980 | $50.0K | 0.00% | −687−5.0% | Reduced |
| Nisa Investment Advisors, LLC | 11,916 | $46.0K | 0.00% | +61+0.5% | Added |
| China Universal Asset Management Co., Ltd. | 11,357 | $43.8K | 0.00% | −649−5.4% | Reduced |
| Invesco Ltd. | 11,331 | $43.7K | 0.00% | −252−2.2% | Reduced |
| The PNC Financial Services Group, Inc. | 9,251 | $35.7K | 0.00% | +32+0.3% | Added |
| Tower Research Capital LLC (TRC) | 7,902 | $30.5K | 0.00% | +6,141+348.7% | Added |
| Police & Firemen's Retirement System of New Jersey | 6,598 | $25.5K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 3,940 | $15.2K | 0.00% | +881+28.8% | Added |
| CoreCap Advisors, LLC | 2,879 | $11.1K | 0.00% | +2,167+304.4% | Added |
| Royal Bank of Canada | 2,806 | $11.0K | 0.00% | −1,261−31.0% | Reduced |
| Ameritas Investment Partners, Inc. | 2,570 | $9.92K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 2,565 | $9.91K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 2,275 | $8.78K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 2,165 | $8.36K | 0.00% | +2,165 | New |
| Mirae Asset Global Investments Co., Ltd. | 1,895 | $7.98K | 0.00% | +8+0.4% | Added |
| New York State Common Retirement Fund | 2,026 | $7.82K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,449 | $5.59K | 0.00% | +260+21.9% | Added |
| Amalgamated Bank | 1,176 | $5.00K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 610 | $2.35K | 0.00% | 00.0% | Unchanged |
| Private Wealth Management Group, LLC | 558 | $2.15K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 542 | $2.09K | 0.00% | −463−46.1% | Reduced |
| Coldstream Capital Management Inc | 535 | $2.07K | 0.00% | +535 | New |
| Simplex Trading, LLC | 263 | $1.00K | 0.00% | −4,905−94.9% | Reduced |
| Daiwa Securities Group Inc. | 350 | $1.00K | 0.00% | +350 | New |
| Massmutual Trust Co FSB | 239 | $923 | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 228 | $880 | 0.00% | −842−78.7% | Reduced |
| Principal Securities, Inc. | 74 | $457 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 49 | $189 | 0.00% | −24−32.9% | Reduced |
| EverSource Wealth Advisors, LLC | 31 | $120 | 0.00% | +31 | New |
| Skopos Labs, Inc. | 19 | $74 | 0.00% | +19 | New |
| Farther Finance Advisors, LLC | 19 | $68 | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 111 | $0 | 0.00% | −30−21.3% | Reduced |
| Capital Advisors, Ltd. LLC | 12 | $0 | 0.00% | 00.0% | Unchanged |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −426,683−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −141,127−100.0% | Sold out |