Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Design Therapeutics, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 83
- +5 vs. Q3 2022
- Shares held
- 40.4M
- +462.0K (+1.2%) vs. Q3 2022
- Total value
- $414.2M
- −$253.1M (−37.9%) vs. Q3 2022
- New holders
- 19
- 29 more added
- Sold out
- 14
- 23 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sr One Capital Management, LP | 6,526,476 | $67.0M | 24.44% | +900,000+16.0% | Added |
| Cormorant Asset Management, LP | 5,150,000 | $52.8M | 3.55% | +150,000+3.0% | Added |
| BlackRock Inc. | 3,508,024 | $36.0M | 0.00% | −91,101−2.5% | Reduced |
| State Street Corp | 3,037,460 | $31.2M | 0.00% | +2,127,991+234.0% | Added |
| Ra Capital Management, L.P. | 2,971,231 | $30.5M | 0.62% | +198,000+7.1% | Added |
| Logos Global Management LP | 2,797,501 | $28.7M | 3.36% | 00.0% | Unchanged |
| Citadel Advisors LLC | 2,502,561 | $25.7M | 0.03% | +80,829+3.3% | Added |
| Avoro Capital Advisors LLC | 2,272,222 | $23.3M | 0.35% | +50,000+2.3% | Added |
| Vanguard Group Inc | 1,561,700 | $16.0M | 0.00% | +9,950+0.6% | Added |
| FMR LLC | 1,119,537 | $11.5M | 0.00% | +36,675+3.4% | Added |
| Janus Henderson Group PLC | 1,105,859 | $11.3M | 0.01% | −397,952−26.5% | Reduced |
| EcoR1 Capital, LLC | 884,903 | $9.08M | 0.28% | −1,634,365−64.9% | Reduced |
| Principal Financial Group Inc | 782,709 | $8.03M | 0.01% | −37,277−4.5% | Reduced |
| Wellington Management Group LLP | 742,740 | $7.62M | 0.00% | −206,033−21.7% | Reduced |
| Baker Bros. Advisors LP | 692,131 | $7.10M | 0.04% | −744,505−51.8% | Reduced |
| Geode Capital Management, LLC | 603,013 | $6.19M | 0.00% | +26,304+4.6% | Added |
| Millennium Management LLC | 516,811 | $5.30M | 0.01% | +375,313+265.2% | Added |
| Rock Springs Capital Management LP | 460,391 | $4.72M | 0.11% | 00.0% | Unchanged |
| Bank of America Corp | 295,860 | $3.04M | 0.00% | +228,971+342.3% | Added |
| Northern Trust Corp | 279,130 | $2.86M | 0.00% | −4,565−1.6% | Reduced |
| Goldman Sachs Group Inc | 274,471 | $2.82M | 0.00% | −719,174−72.4% | Reduced |
| Rafferty Asset Management, LLC | 243,585 | $2.50M | 0.02% | +212,534+684.5% | Added |
| Charles Schwab Investment Management Inc | 230,912 | $2.37M | 0.00% | +6,352+2.8% | Added |
| UBS Group AG | 156,027 | $1.60M | 0.00% | +156,027 | New |
| Dimensional Fund Advisors LP | 154,120 | $1.58M | 0.00% | +25,248+19.6% | Added |
| Barclays PLC | 130,999 | $1.34M | 0.00% | +109,401+506.5% | Added |
| Bank of New York Mellon Corp | 126,484 | $1.30M | 0.00% | +1,277+1.0% | Added |
| Marshall Wace, LLP | 112,818 | $1.16M | 0.00% | +112,818 | New |
| Citigroup Inc | 109,660 | $1.13M | 0.00% | +75,393+220.0% | Added |
| Cubist Systematic Strategies, LLC | 109,303 | $1.12M | 0.01% | +109,303 | New |
| Nuveen Asset Management, LLC | 94,072 | $965.0K | 0.00% | −16,062−14.6% | Reduced |
| Ghost Tree Capital, LLC | 82,853 | $850.0K | 0.36% | −17,147−17.1% | Reduced |
| Acadian Asset Management LLC | 57,957 | $594.0K | 0.00% | +57,957 | New |
| Silverarc Capital Management, LLC | 57,025 | $585.1K | 0.20% | +57,025 | New |
| Rhumbline Advisers | 51,616 | $530.0K | 0.00% | −156−0.3% | Reduced |
| ExodusPoint Capital Management, LP | 50,731 | $521.0K | 0.01% | −1,110−2.1% | Reduced |
| Morgan Stanley | 41,424 | $425.0K | 0.00% | −17,511−29.7% | Reduced |
| Two Sigma Investments, LP | 35,093 | $360.1K | 0.00% | +35,093 | New |
| Bellevue Group AG | 34,881 | $357.9K | 0.00% | 00.0% | Unchanged |
| Jump Financial, LLC | 30,400 | $311.9K | 0.02% | +30,400 | New |
| Alliancebernstein L.P. | 27,600 | $283.2K | 0.00% | +6,400+30.2% | Added |
| New York State Common Retirement Fund | 24,466 | $251.0K | 0.00% | +220+0.9% | Added |
| Susquehanna International Group, LLP | 24,456 | $250.9K | 0.00% | +6,140+33.5% | Added |
| MetLife Investment Management | 22,045 | $226.2K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 19,800 | $203.0K | 0.00% | −73,352−78.7% | Reduced |
| Deutsche Bank AG | 17,841 | $183.0K | 0.00% | +4,082+29.7% | Added |
| Tudor Investment Corp Et Al | 17,684 | $181.0K | 0.00% | −10,182−36.5% | Reduced |
| American International Group, Inc. | 16,027 | $164.4K | 0.00% | −59−0.4% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 16,689 | $163.1K | 0.00% | +16,689 | New |
| Virtus ETF Advisers LLC | 15,774 | $161.8K | 0.08% | +7,999+102.9% | Added |
| Mirae Asset Global Investments Co., Ltd. | 15,548 | $159.5K | 0.00% | +22+0.1% | Added |
| Virtus Investment Advisers, Inc. | 14,400 | $147.7K | 0.10% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 13,619 | $140.0K | 0.02% | +13,619 | New |
| Manufacturers Life Insurance Company, The | 13,627 | $139.8K | 0.00% | −28,658−67.8% | Reduced |
| California State Teachers Retirement System | 13,527 | $138.8K | 0.00% | +153+1.1% | Added |
| Voya Investment Management LLC | 13,162 | $135.0K | 0.00% | −14,085−51.7% | Reduced |
| State Board of Administration of Florida Retirement System | 12,630 | $129.6K | 0.00% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 12,523 | $128.0K | 0.01% | +12,523 | New |
| Envestnet Asset Management Inc | 12,236 | $125.5K | 0.00% | +12,236 | New |
| Ikarian Capital, LLC | 11,568 | $118.7K | 0.05% | +11,568 | New |
| Walleye Capital LLC | 10,703 | $109.8K | 0.00% | +10,703 | New |
| Amalgamated Bank | 4,291 | $44.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 3,919 | $40.0K | 0.00% | +3,505+846.6% | Added |
| Tower Research Capital LLC (TRC) | 3,241 | $33.0K | 0.00% | −5,769−64.0% | Reduced |
| Legal & General Group Plc | 3,127 | $32.1K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 2,249 | $23.1K | 0.00% | +222+11.0% | Added |
| Ameritas Investment Partners, Inc. | 2,570 | $22.0K | 0.00% | 00.0% | Unchanged |
| Dark Forest Capital Management LP | 1,669 | $17.1K | 0.00% | +1,669 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1,115 | $11.4K | 0.00% | −214−16.1% | Reduced |
| Assetmark, Inc | 1,111 | $11.4K | 0.00% | +359+47.7% | Added |
| High Net Worth Advisory Group LLC | 1,000 | $10.3K | 0.00% | +1,000 | New |
| Russell Investments Group, Ltd. | 992 | $10.2K | 0.00% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 744 | $7.63K | 0.00% | +744 | New |
| China Universal Asset Management Co., Ltd. | 568 | $5.83K | 0.00% | +45+8.6% | Added |
| Group One Trading, L.P. | 500 | $5.13K | 0.00% | +500 | New |
| Allspring Global Investments Holdings, LLC | 201 | $2.06K | 0.00% | −5−2.4% | Reduced |
| Advisor Group Holdings, Inc. | 220 | $2.00K | 0.00% | −101−31.5% | Reduced |
| Daiwa Securities Group Inc. | 162 | $2.00K | 0.00% | 00.0% | Unchanged |
| TCI Wealth Advisors, Inc. | 84 | $862 | 0.00% | +84 | New |
| Credit Suisse AG | 1 | $10 | 0.00% | −191−99.5% | Reduced |
| Rockefeller Capital Management L.P. | 61 | $0 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 8 | $0 | 0.00% | +3+60.0% | Added |
| CWM, LLC | 24 | $0 | 0.00% | +24 | New |
| Tekla Capital Management LLC | 0 | $0 | 0.00% | −280,523−100.0% | Sold out |
| Price T Rowe Associates Inc | 0 | $0 | 0.00% | −280,120−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −125,000−100.0% | Sold out |
| HighVista Strategies LLC | 0 | $0 | 0.00% | −38,152−100.0% | Sold out |
| DekaBank Deutsche Girozentrale | 0 | $0 | 0.00% | −18,700−100.0% | Sold out |
| TD Asset Management Inc | 0 | $0 | 0.00% | −16,318−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −11,296−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −11,134−100.0% | Sold out |
| Invesco Ltd. | 0 | $0 | 0.00% | −10,058−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −9,936−100.0% | Sold out |
| Wells Fargo & Company | 0 | $0 | 0.00% | −406−100.0% | Sold out |
| Howe & Rusling Inc | 0 | $0 | 0.00% | −70−100.0% | Sold out |
| Nisa Investment Advisors, LLC | 0 | $0 | 0.00% | −34−100.0% | Sold out |
| Lindbrook Capital, LLC | 0 | $0 | 0.00% | −78−100.0% | Sold out |
| FourThought Financial, LLC | – | – | – | – | Not filed |