Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.5M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Design Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 136
- +12 vs. Q1 2026
- Shares held
- 43.3M
- +5.32M (+14.0%) vs. Q1 2026
- Total value
- $626.5M
- +$222.3M (+55.0%) vs. Q1 2026
- New holders
- 28
- 62 more added
- Sold out
- 16
- 32 more reduced
1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.5M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.8M |
| Q3 2025 | 95 | $271.4M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.5M |
| Q2 2024 | 95 | $124.4M |
| Q1 2024 | 93 | $127.9M |
| Q4 2023 | 88 | $85.6M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $228.8M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $692.4M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sr One Capital Management, LP | 6,526,476 | $94.4M | 9.09% | 00.0% | Unchanged |
| Logos Global Management LP | 3,000,000 | $43.4M | 1.87% | +1,050,000+53.8% | Added |
| Baker Bros. Advisors LP | 2,678,430 | $38.8M | 0.19% | +92,452+3.6% | Added |
| Driehaus Capital Management LLC | 2,661,115 | $38.5M | 0.22% | +916,128+52.5% | Added |
| BlackRock, Inc. | 2,660,024 | $38.5M | 0.00% | +526,260+24.7% | Added |
| Point72 Asset Management, L.P. | 2,366,453 | $34.2M | 0.05% | −356,301−13.1% | Reduced |
| Trails Edge Capital Partners, LP | 2,001,282 | $29.0M | 4.60% | +1,149,269+134.9% | Added |
| Frazier Life Sciences Management, L.P. | 1,809,854 | $26.2M | 0.57% | +1,809,854 | New |
| Vivo Capital, LLC | 1,612,903 | $23.3M | 2.13% | 00.0% | Unchanged |
| Vanguard Capital Management LLC | 1,571,022 | $22.7M | 0.00% | +221,172+16.4% | Added |
| Caption Management, LLC | 1,118,098 | $16.2M | 0.57% | +1,031,390+1,189.5% | Added |
| Almitas Capital LLC | 1,026,893 | $14.9M | 3.56% | −503,442−32.9% | Reduced |
| Geode Capital Management, LLC | 958,417 | $13.9M | 0.00% | +265,899+38.4% | Added |
| Sofinnova Investments, Inc. | 865,135 | $12.5M | 0.67% | +865,135 | New |
| FMR LLC | 776,462 | $11.2M | 0.00% | −21,949−2.7% | Reduced |
| Morgan Stanley | 765,425 | $11.1M | 0.00% | +108,860+16.6% | Added |
| State Street Corp | 736,221 | $10.7M | 0.00% | +76,646+11.6% | Added |
| Woodline Partners LP | 700,354 | $10.1M | 0.03% | −261,147−27.2% | Reduced |
| Dimensional Fund Advisors LP | 694,743 | $10.1M | 0.00% | +262,903+60.9% | Added |
| Goldman Sachs Group Inc | 656,584 | $9.50M | 0.00% | +151,866+30.1% | Added |
| Jacobs Levy Equity Management, Inc | 565,597 | $8.18M | 0.03% | +276,212+95.4% | Added |
| Acadian Asset Management LLC | 537,479 | $7.77M | 0.01% | −79,002−12.8% | Reduced |
| Siren, L.L.C. | 523,212 | $7.57M | 0.15% | +523,212 | New |
| Qube Research & Technologies Ltd | 437,079 | $6.32M | 0.01% | +402,896+1,178.6% | Added |
| Renaissance Technologies LLC | 387,913 | $5.61M | 0.01% | −20,287−5.0% | Reduced |
| Kennedy Capital Management, Inc. | 384,036 | $5.56M | 0.10% | +112,482+41.4% | Added |
| Northern Trust Corp | 353,197 | $5.11M | 0.00% | +52,918+17.6% | Added |
| Algert Global LLC | 296,085 | $4.28M | 0.05% | +91,346+44.6% | Added |
| Acuta Capital Partners, LLC | 282,564 | $4.09M | 2.85% | +136,664+93.7% | Added |
| Charles Schwab Investment Management Inc | 271,264 | $3.93M | 0.00% | +29,779+12.3% | Added |
| Vanguard Portfolio Management LLC | 251,442 | $3.64M | 0.00% | +112,877+81.5% | Added |
| Vanguard Fiduciary Trust Co | 230,202 | $3.33M | 0.00% | +34,544+17.7% | Added |
| Prudential Financial Inc | 224,170 | $3.24M | 0.00% | +178,360+389.3% | Added |
| D. E. Shaw & Co., Inc. | 195,645 | $2.83M | 0.00% | −274,625−58.4% | Reduced |
| Eversept Partners, LP | 190,000 | $2.75M | 0.15% | +190,000 | New |
| KVP Capital Advisors, LP | 185,000 | $2.68M | 1.96% | +185,000 | New |
| J. Goldman & Co LP | 176,770 | $2.56M | 0.09% | +176,770 | New |
| Millennium Management LLC | 147,714 | $2.14M | 0.00% | +38,786+35.6% | Added |
| Raymond James Financial Inc | 138,521 | $2.00M | 0.00% | +30,072+27.7% | Added |
| Balyasny Asset Management LLC | 111,103 | $1.61M | 0.00% | +111,103 | New |
| Elmind Capital, LP | 107,900 | $1.56M | 0.39% | −100,000−48.1% | Reduced |
| Nuveen, LLC | 104,734 | $1.52M | 0.00% | −22,081−17.4% | Reduced |
| DAFNA Capital Management LLC | 102,600 | $1.48M | 0.28% | +102,600 | New |
| Bank of New York Mellon Corp | 92,069 | $1.33M | 0.00% | +12,424+15.6% | Added |
| China Universal Asset Management Co., Ltd. | 89,940 | $1.30M | 0.08% | +54,831+156.2% | Added |
| Citadel Advisors LLC | 81,971 | $1.19M | 0.00% | −149,542−64.6% | Reduced |
| SummitTX Capital, L.P. | 80,663 | $1.17M | 0.03% | +80,663 | New |
| American Century Companies Inc | 76,825 | $1.11M | 0.00% | +11,187+17.0% | Added |
| Palumbo Wealth Management LLC | 71,744 | $1.04M | 0.22% | +336+0.5% | Added |
| AQR Capital Management LLC | 71,114 | $1.03M | 0.00% | +45,157+174.0% | Added |
| Ameriprise Financial Inc | 67,598 | $978.1K | 0.00% | +32,608+93.2% | Added |
| Russell Investments Group, Ltd. | 66,859 | $967.4K | 0.00% | +41,422+162.8% | Added |
| Alps Advisors Inc | 63,391 | $917.3K | 0.00% | +13,182+26.3% | Added |
| State of Wisconsin Investment Board | 59,249 | $857.3K | 0.00% | +10,035+20.4% | Added |
| STRS Ohio | 50,500 | $730.7K | 0.00% | +5,800+13.0% | Added |
| Verdad Advisers, LP | 47,557 | $688.1K | 0.66% | −44,753−48.5% | Reduced |
| Bank of America Corp | 43,728 | $632.7K | 0.00% | +20,464+88.0% | Added |
| ExodusPoint Capital Management, LP | 41,286 | $597.4K | 0.01% | +41,286 | New |
| Rhumbline Advisers | 38,132 | $551.8K | 0.00% | +3,272+9.4% | Added |
| Vanguard Global Advisers, LLC | 35,534 | $514.2K | 0.00% | +23,695+200.1% | Added |
| UBS Group AG | 34,761 | $503.0K | 0.00% | +17,670+103.4% | Added |
| Susquehanna Portfolio Strategies, LLC | 33,375 | $482.9K | 0.01% | +33,375 | New |
| Two Sigma Investments, LP | 32,925 | $476.4K | 0.00% | +16,625+102.0% | Added |
| Canada Pension Plan Investment Board | 32,600 | $471.7K | 0.00% | −27,800−46.0% | Reduced |
| Oppenheimer & Co Inc | 32,087 | $464.3K | 0.00% | +32,087 | New |
| Alliancebernstein L.P. | 43,230 | $460.0K | 0.00% | −2,890−6.3% | Reduced |
| Deutsche Bank AG | 30,613 | $443.0K | 0.00% | +9,969+48.3% | Added |
| Virtus Investment Advisers, Inc. | 29,827 | $431.6K | 0.10% | +29,827 | New |
| Squarepoint Ops LLC | 29,630 | $428.7K | 0.00% | −56,487−65.6% | Reduced |
| Trexquant Investment LP | 28,150 | $407.3K | 0.00% | −88,961−76.0% | Reduced |
| Wells Fargo & Company | 28,072 | $406.2K | 0.00% | +19,045+211.0% | Added |
| CI Private Wealth, LLC | 27,169 | $393.1K | 0.00% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 27,000 | $390.7K | 0.01% | −25,000−48.1% | Reduced |
| Quantinno Capital Management LP | 26,901 | $389.3K | 0.00% | +12,773+90.4% | Added |
| Price T Rowe Associates Inc | 25,606 | $371.0K | 0.00% | +9,236+56.4% | Added |
| SEI Investments Co | 22,740 | $329.1K | 0.00% | −110,463−82.9% | Reduced |
| XTX Topco Ltd | 22,383 | $323.9K | 0.00% | −38,556−63.3% | Reduced |
| AlphaCentric Advisors LLC | 21,537 | $311.6K | 0.26% | +306+1.4% | Added |
| Invesco Ltd. | 21,429 | $310.1K | 0.00% | −120,491−84.9% | Reduced |
| Public Employees Retirement System of Ohio | 20,700 | $299.5K | 0.00% | +5,507+36.2% | Added |
| MetLife Investment Management | 20,609 | $298.2K | 0.00% | +5,360+35.1% | Added |
| Wellington Management Group LLP | 19,400 | $280.7K | 0.00% | +19,400 | New |
| JPMorgan Chase & Co | 16,904 | $240.7K | 0.00% | +2,770+19.6% | Added |
| Citigroup Inc | 15,880 | $229.8K | 0.00% | +11,617+272.5% | Added |
| Creative Planning | 15,844 | $229.3K | 0.00% | +15,844 | New |
| Susquehanna International Group, LLP | 15,650 | $226.5K | 0.00% | +15,650 | New |
| Nisa Investment Advisors, LLC | 14,824 | $214.5K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 14,171 | $205.1K | 0.00% | +2,808+24.7% | Added |
| Y-Intercept (Hong Kong) Ltd | 12,910 | $186.8K | 0.00% | +12,910 | New |
| Susquehanna Fundamental Investments, LLC | 12,553 | $181.6K | 0.00% | +12,553 | New |
| Royal Bank of Canada | 12,254 | $178.0K | 0.00% | +888+7.8% | Added |
| Barclays PLC | 11,707 | $169.4K | 0.00% | −44,083−79.0% | Reduced |
| New York State Common Retirement Fund | 10,826 | $156.7K | 0.00% | +8,800+434.4% | Added |
| Gsa Capital Partners LLP | 10,328 | $149.0K | 0.01% | +10,328 | New |
| Police & Firemen's Retirement System of New Jersey | 9,849 | $142.5K | 0.00% | +3,251+49.3% | Added |
| Caz Investments LP | 7,000 | $101.3K | 0.03% | +3,500+100.0% | Added |
| BNP Paribas Arbitrage, SA | 5,751 | $83.2K | 0.00% | −44,521−88.6% | Reduced |
| Clearstead Advisors, LLC | 5,610 | $81.2K | 0.00% | +5,000+819.7% | Added |
| Tower Research Capital LLC (TRC) | 4,908 | $71.0K | 0.00% | +3,363+217.7% | Added |
| Rockefeller Capital Management L.P. | 3,684 | $53.3K | 0.00% | 00.0% | Unchanged |