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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Design Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
136
+12 vs. Q1 2026
Shares held
43.3M
+5.32M (+14.0%) vs. Q1 2026
Total value
$626.4M
+$222.3M (+55.0%) vs. Q1 2026
New holders
28
61 more added
Sold out
16
32 more reduced

1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 136 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ2 2026: $626.4M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding DSGN in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC12$00.00%00.0%Unchanged
Essential Partners LLC1$140.00%00.0%Unchanged
SJS Investment Consulting Inc.4$580.00%+4New
SBI Securities Co., Ltd.10$1450.00%+10New
True Wealth Design, LLC18$2610.00%+17+1,700.0%Added
Farther Finance Advisors, LLC20$2890.00%−366−94.8%Reduced
Rothschild Investment LLC22$3180.00%−1−4.3%Reduced
EverSource Wealth Advisors, LLC25$3620.00%+15+150.0%Added
US Bancorp26$3760.00%−35−57.4%Reduced
Quarry LP31$4490.00%+31New
Silver Grove Financial Group, Inc.58$8390.00%+58New
National Bank of Canada83$1.20K0.00%+74+822.2%Added
Versant Capital Management, Inc86$1.24K0.00%+86New
Allworth Financial LP96$1.39K0.00%−34−26.2%Reduced
Sterling Capital Management LLC108$1.56K0.00%−683−86.3%Reduced
Optiver Holding B.V.160$2.31K0.00%−64−28.6%Reduced
Simplex Trading, LLC172$2.49K0.00%+172New
SRS Capital Advisors, Inc.180$2.61K0.00%+180New
Larson Financial Group LLC181$2.62K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.225$3.25K0.00%−81−26.5%Reduced
Massmutual Trust Co FSB239$3.46K0.00%00.0%Unchanged
Stone House Investment Management, LLC239$3.46K0.00%00.0%Unchanged
UMA Financial Services, Inc.268$3.88K0.00%00.0%Unchanged
California State Teachers Retirement System335$4.85K0.00%−957−74.1%Reduced
Private Wealth Management Group, LLC533$7.71K0.00%00.0%Unchanged
Allied Private Wealth LLC880$13.4K0.01%+880New
UBS Asset Management Americas Inc1,143$16.5K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,209$17.5K0.00%−62−4.9%Reduced
Caitong International Asset Management Co., Ltd1,259$18.2K0.00%+1,258+125,800.0%Added
GAMMA Investing LLC1,450$21.0K0.00%−22−1.5%Reduced
The PNC Financial Services Group, Inc.1,816$26.3K0.00%00.0%Unchanged
State of Wyoming2,566$37.1K0.00%+2,566New
Mirae Asset Global Investments Co., Ltd.2,793$40.4K0.00%−178−6.0%Reduced
Ameritas Investment Partners, Inc.2,793$40.4K0.00%+223+8.7%Added
Legal & General Group Plc2,987$43.2K0.00%+910+43.8%Added
Zurcher Kantonalbank (Zurich Cantonalbank)3,025$43.8K0.00%+1,431+89.8%Added
Caz Investments LP3,500$50.6K0.02%00.0%Unchanged
Rockefeller Capital Management L.P.3,684$53.3K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)4,908$71.0K0.00%+3,363+217.7%Added
Clearstead Advisors, LLC5,610$81.2K0.00%+5,000+819.7%Added
BNP Paribas Arbitrage, SA5,751$83.2K0.00%−44,521−88.6%Reduced
Police & Firemen's Retirement System of New Jersey9,849$142.5K0.00%+3,251+49.3%Added
Gsa Capital Partners LLP10,328$149.0K0.01%+10,328New
New York State Common Retirement Fund10,826$156.7K0.00%+8,800+434.4%Added
Barclays PLC11,707$169.4K0.00%−44,083−79.0%Reduced
Royal Bank of Canada12,254$178.0K0.00%+888+7.8%Added
Susquehanna Fundamental Investments, LLC12,553$181.6K0.00%+12,553New
Y-Intercept (Hong Kong) Ltd12,910$186.8K0.00%+12,910New
Mirae Asset Global ETFs Holdings Ltd.14,171$205.1K0.00%+2,808+24.7%Added
Nisa Investment Advisors, LLC14,824$214.5K0.00%00.0%Unchanged
Susquehanna International Group, LLP15,650$226.5K0.00%+15,650New
Creative Planning15,844$229.3K0.00%+15,844New
Citigroup Inc15,880$229.8K0.00%+11,617+272.5%Added
JPMorgan Chase & Co16,904$240.7K0.00%+2,770+19.6%Added
Wellington Management Group LLP19,400$280.7K0.00%+19,400New
MetLife Investment Management20,609$298.2K0.00%+5,360+35.1%Added
Public Employees Retirement System of Ohio20,700$299.5K0.00%+5,507+36.2%Added
Invesco Ltd.21,429$310.1K0.00%−120,491−84.9%Reduced
AlphaCentric Advisors LLC21,537$311.6K0.26%+306+1.4%Added
XTX Topco Ltd22,383$323.9K0.00%−38,556−63.3%Reduced
SEI Investments Co22,740$329.1K0.00%−110,463−82.9%Reduced
Price T Rowe Associates Inc25,606$371.0K0.00%+9,236+56.4%Added
Quantinno Capital Management LP26,901$389.3K0.00%+12,773+90.4%Added
Bridgeway Capital Management, LLC27,000$390.7K0.01%−25,000−48.1%Reduced
CI Private Wealth, LLC27,169$393.1K0.00%00.0%Unchanged
Wells Fargo & Company28,072$406.2K0.00%+19,045+211.0%Added
Trexquant Investment LP28,150$407.3K0.00%−88,961−76.0%Reduced
Squarepoint Ops LLC29,630$428.7K0.00%−56,487−65.6%Reduced
Virtus Investment Advisers, Inc.29,827$431.6K0.10%+29,827New
Deutsche Bank AG30,613$443.0K0.00%+9,969+48.3%Added
Alliancebernstein L.P.43,230$460.0K0.00%−2,890−6.3%Reduced
Oppenheimer & Co Inc32,087$464.3K0.00%+32,087New
Canada Pension Plan Investment Board32,600$471.7K0.00%−27,800−46.0%Reduced
Two Sigma Investments, LP32,925$476.4K0.00%+16,625+102.0%Added
Susquehanna Portfolio Strategies, LLC33,375$482.9K0.01%+33,375New
UBS Group AG34,761$503.0K0.00%+17,670+103.4%Added
Vanguard Global Advisers, LLC35,534$514.2K0.00%+23,695+200.1%Added
Rhumbline Advisers38,132$551.8K0.00%+3,272+9.4%Added
ExodusPoint Capital Management, LP41,286$597.4K0.01%+41,286New
Bank of America Corp43,728$632.7K0.00%+20,464+88.0%Added
Verdad Advisers, LP47,557$688.1K0.66%−44,753−48.5%Reduced
STRS Ohio50,500$730.7K0.00%+5,800+13.0%Added
State of Wisconsin Investment Board59,249$857.3K0.00%+10,035+20.4%Added
Alps Advisors Inc63,391$917.3K0.00%+13,182+26.3%Added
Russell Investments Group, Ltd.66,859$967.4K0.00%+41,422+162.8%Added
Ameriprise Financial Inc67,598$978.1K0.00%+32,608+93.2%Added
AQR Capital Management LLC71,114$1.03M0.00%+45,157+174.0%Added
Palumbo Wealth Management LLC71,744$1.04M0.22%+336+0.5%Added
American Century Companies Inc76,825$1.11M0.00%+11,187+17.0%Added
SummitTX Capital, L.P.80,663$1.17M0.03%+80,663New
Citadel Advisors LLC81,971$1.19M0.00%−149,542−64.6%Reduced
China Universal Asset Management Co., Ltd.89,940$1.30M0.08%+54,831+156.2%Added
Bank of New York Mellon Corp92,069$1.33M0.00%+12,424+15.6%Added
DAFNA Capital Management LLC102,600$1.48M0.28%+102,600New
Nuveen, LLC104,734$1.52M0.00%−22,081−17.4%Reduced
Elmind Capital, LP107,900$1.56M0.39%−100,000−48.1%Reduced
Balyasny Asset Management LLC111,103$1.61M0.00%+111,103New
Raymond James Financial Inc138,521$2.00M0.00%+30,072+27.7%Added
Millennium Management LLC147,714$2.14M0.00%+38,786+35.6%Added
J. Goldman & Co LP176,770$2.56M0.09%+176,770New