Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Design Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 98
- +4 vs. Q4 2024
- Shares held
- 34.5M
- +1.16M (+3.5%) vs. Q4 2024
- Total value
- $133.0M
- −$72.5M (−35.3%) vs. Q4 2024
- New holders
- 14
- 28 more added
- Sold out
- 10
- 36 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| CWM, LLC | 111 | $0 | 0.00% | −30−21.3% | Reduced |
| Capital Advisors, Ltd. LLC | 12 | $0 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 19 | $68 | 0.00% | 00.0% | Unchanged |
| Skopos Labs, Inc. | 19 | $74 | 0.00% | +19 | New |
| EverSource Wealth Advisors, LLC | 31 | $120 | 0.00% | +31 | New |
| Advisor Group Holdings, Inc. | 49 | $189 | 0.00% | −24−32.9% | Reduced |
| Principal Securities, Inc. | 74 | $457 | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 228 | $880 | 0.00% | −842−78.7% | Reduced |
| Massmutual Trust Co FSB | 239 | $923 | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 263 | $1.00K | 0.00% | −4,905−94.9% | Reduced |
| Daiwa Securities Group Inc. | 350 | $1.00K | 0.00% | +350 | New |
| Coldstream Capital Management Inc | 535 | $2.07K | 0.00% | +535 | New |
| Sterling Capital Management LLC | 542 | $2.09K | 0.00% | −463−46.1% | Reduced |
| Private Wealth Management Group, LLC | 558 | $2.15K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 610 | $2.35K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 1,176 | $5.00K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,449 | $5.59K | 0.00% | +260+21.9% | Added |
| New York State Common Retirement Fund | 2,026 | $7.82K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 1,895 | $7.98K | 0.00% | +8+0.4% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 2,165 | $8.36K | 0.00% | +2,165 | New |
| California State Teachers Retirement System | 2,275 | $8.78K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 2,565 | $9.91K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 2,570 | $9.92K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 2,806 | $11.0K | 0.00% | −1,261−31.0% | Reduced |
| CoreCap Advisors, LLC | 2,879 | $11.1K | 0.00% | +2,167+304.4% | Added |
| Russell Investments Group, Ltd. | 3,940 | $15.2K | 0.00% | +881+28.8% | Added |
| Police & Firemen's Retirement System of New Jersey | 6,598 | $25.5K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 7,902 | $30.5K | 0.00% | +6,141+348.7% | Added |
| The PNC Financial Services Group, Inc. | 9,251 | $35.7K | 0.00% | +32+0.3% | Added |
| Invesco Ltd. | 11,331 | $43.7K | 0.00% | −252−2.2% | Reduced |
| China Universal Asset Management Co., Ltd. | 11,357 | $43.8K | 0.00% | −649−5.4% | Reduced |
| Nisa Investment Advisors, LLC | 11,916 | $46.0K | 0.00% | +61+0.5% | Added |
| SG Americas Securities, LLC | 12,980 | $50.0K | 0.00% | −687−5.0% | Reduced |
| Manufacturers Life Insurance Company, The | 12,957 | $50.0K | 0.00% | −113−0.9% | Reduced |
| Price T Rowe Associates Inc | 13,069 | $51.0K | 0.00% | +618+5.0% | Added |
| Velan Capital Investment Management LP | 14,000 | $54.0K | 0.06% | +14,000 | New |
| Kennedy Capital Management, Inc. | 14,383 | $55.5K | 0.00% | +117+0.8% | Added |
| Caz Investments LP | 15,000 | $58.0K | 0.42% | 00.0% | Unchanged |
| Corebridge Financial, Inc. | 15,383 | $59.4K | 0.00% | −227−1.5% | Reduced |
| Mariner, LLC | 15,471 | $59.7K | 0.00% | −786−4.8% | Reduced |
| Jacobs Levy Equity Management, Inc | 17,482 | $67.5K | 0.00% | −779−4.3% | Reduced |
| Jane Street Group, LLC | 18,125 | $70.0K | 0.00% | +18,125 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 18,737 | $72.3K | 0.00% | +780+4.3% | Added |
| Wells Fargo & Company | 18,846 | $72.7K | 0.00% | +418+2.3% | Added |
| MetLife Investment Management | 18,962 | $73.2K | 0.00% | −372−1.9% | Reduced |
| JPMorgan Chase & Co | 19,277 | $74.4K | 0.00% | −69,938−78.4% | Reduced |
| Intech Investment Management LLC | 20,550 | $79.3K | 0.00% | +2,885+16.3% | Added |
| State of Wisconsin Investment Board | 21,962 | $84.8K | 0.00% | +21,962 | New |
| Bank of America Corp | 22,166 | $85.6K | 0.00% | −12,994−37.0% | Reduced |
| STRS Ohio | 22,600 | $87.2K | 0.00% | −10,000−30.7% | Reduced |
| Citigroup Inc | 22,879 | $88.3K | 0.00% | −1,597−6.5% | Reduced |
| CI Private Wealth, LLC | 26,965 | $104.1K | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 28,129 | $108.6K | 0.00% | +35+0.1% | Added |
| AQR Capital Management LLC | 31,740 | $122.5K | 0.00% | +1,885+6.3% | Added |
| UBS Group AG | 32,819 | $126.7K | 0.00% | −33,768−50.7% | Reduced |
| Assenagon Asset Management S.A. | 36,917 | $142.5K | 0.00% | −19,700−34.8% | Reduced |
| Alliancebernstein L.P. | 42,090 | $162.5K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 43,223 | $166.8K | 0.00% | +5,911+15.8% | Added |
| American Century Companies Inc | 44,415 | $171.4K | 0.00% | +5,300+13.5% | Added |
| Rhumbline Advisers | 46,369 | $179.0K | 0.00% | −6,563−12.4% | Reduced |
| BNP Paribas Arbitrage, SA | 52,872 | $204.1K | 0.00% | +12,583+31.2% | Added |
| Prudential Financial Inc | 56,405 | $217.7K | 0.00% | +90+0.2% | Added |
| Palumbo Wealth Management LLC | 58,278 | $225.0K | 0.08% | +3,582+6.5% | Added |
| Lynx1 Capital Management LP | 65,954 | $254.6K | 0.09% | +65,954 | New |
| Gsa Capital Partners LLP | 72,149 | $278.0K | 0.03% | −46,179−39.0% | Reduced |
| Barclays PLC | 84,006 | $324.3K | 0.00% | −19,565−18.9% | Reduced |
| Millennium Management LLC | 87,988 | $339.6K | 0.00% | +87,988 | New |
| Bank of New York Mellon Corp | 95,348 | $368.0K | 0.00% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 113,800 | $439.3K | 0.01% | −14,600−11.4% | Reduced |
| Two Sigma Investments, LP | 128,747 | $497.0K | 0.00% | −75,184−36.9% | Reduced |
| Wellington Management Group LLP | 141,519 | $546.3K | 0.00% | +141,519 | New |
| Two Sigma Advisers, LP | 146,700 | $566.3K | 0.00% | −87,200−37.3% | Reduced |
| Nuveen, LLC | 147,228 | $568.3K | 0.00% | +147,228 | New |
| Morgan Stanley | 247,878 | $956.8K | 0.00% | −98,305−28.4% | Reduced |
| Charles Schwab Investment Management Inc | 258,375 | $997.3K | 0.00% | −6,300−2.4% | Reduced |
| Renaissance Technologies LLC | 265,000 | $1.02M | 0.00% | +11,500+4.5% | Added |
| Goldman Sachs Group Inc | 266,016 | $1.03M | 0.00% | −31,113−10.5% | Reduced |
| Dimensional Fund Advisors LP | 288,602 | $1.11M | 0.00% | +73,337+34.1% | Added |
| Northern Trust Corp | 373,653 | $1.44M | 0.00% | −14,472−3.7% | Reduced |
| D. E. Shaw & Co., Inc. | 395,251 | $1.53M | 0.00% | −117,079−22.9% | Reduced |
| MPM Oncology Impact Management LP | 562,943 | $2.17M | 0.37% | +3,396+0.6% | Added |
| Acadian Asset Management LLC | 630,953 | $2.43M | 0.01% | +63,349+11.2% | Added |
| Woodline Partners LP | 645,694 | $2.49M | 0.02% | +645,694 | New |
| State Street Corp | 714,074 | $2.76M | 0.00% | −9,245−1.3% | Reduced |
| Geode Capital Management, LLC | 775,497 | $2.99M | 0.00% | +13,857+1.8% | Added |
| Kynam Capital Management, LP | 904,017 | $3.49M | 0.30% | +904,017 | New |
| Driehaus Capital Management LLC | 913,399 | $3.53M | 0.03% | +137,317+17.7% | Added |
| FMR LLC | 948,050 | $3.66M | 0.00% | −3,832−0.4% | Reduced |
| Citadel Advisors LLC | 963,460 | $3.72M | 0.00% | +4,667+0.5% | Added |
| Vanguard Group Inc | 1,427,467 | $5.51M | 0.00% | −3,278−0.2% | Reduced |
| Almitas Capital LLC | 1,452,896 | $5.61M | 1.86% | +129,229+9.8% | Added |
| Tang Capital Management LLC | 1,680,975 | $6.49M | 0.36% | +200,000+13.5% | Added |
| Baker Bros. Advisors LP | 1,743,725 | $6.73M | 0.07% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 1,817,858 | $7.02M | 0.02% | −38,892−2.1% | Reduced |
| Frazier Life Sciences Management, L.P. | 1,953,547 | $7.54M | 0.34% | 00.0% | Unchanged |
| BlackRock, Inc. | 2,479,963 | $9.57M | 0.00% | −99,636−3.9% | Reduced |
| Logos Global Management LP | 4,217,627 | $16.3M | 2.89% | 00.0% | Unchanged |
| Sr One Capital Management, LP | 6,526,476 | $25.2M | 6.47% | 00.0% | Unchanged |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −426,683−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −141,127−100.0% | Sold out |