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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Design Therapeutics, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
96
+13 vs. Q4 2022
Shares held
38.7M
−1.68M (−4.2%) vs. Q4 2022
Total value
$223.3M
−$190.9M (−46.1%) vs. Q4 2022
New holders
32
23 more added
Sold out
19
27 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 96 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ1 2023: $223.3M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q4 2022.

Institutions holding DSGN in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd8$00.00%00.0%Unchanged
Nisa Investment Advisors, LLC17$00.00%+17New
Zurcher Kantonalbank (Zurich Cantonalbank)1$60.00%−1,114−99.9%Reduced
Allworth Financial LP36$2080.00%+36New
Parallel Advisors, LLC50$2890.00%+50New
EverSource Wealth Advisors, LLC79$4560.00%+79New
Ellevest, Inc.100$5770.00%+100New
Daiwa Securities Group Inc.162$1.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.203$1.17K0.00%−17−7.7%Reduced
UBS Group AG206$1.19K0.00%−155,821−99.9%Reduced
US Bancorp479$2.76K0.00%+479New
Simplex Trading, LLC537$3.00K0.00%+537New
Clearstead Advisors, LLC610$3.52K0.00%+610New
Quadrant Capital Group LLC616$3.56K0.00%+616New
Federated Hermes, Inc.641$3.70K0.00%−103−13.8%Reduced
China Universal Asset Management Co., Ltd.758$4.37K0.00%+190+33.5%Added
Russell Investments Group, Ltd.992$5.72K0.00%00.0%Unchanged
Signaturefd, LLC1,349$7.78K0.00%+1,349New
Lindbrook Capital, LLC1,535$8.86K0.00%+1,535New
Assetmark, Inc1,658$9.57K0.00%+547+49.2%Added
Metropolitan Life Insurance Co2,016$11.6K0.00%−233−10.4%Reduced
Royal Bank of Canada2,066$12.0K0.00%−1,853−47.3%Reduced
Tower Research Capital LLC (TRC)2,099$12.0K0.00%−1,142−35.2%Reduced
Ameritas Investment Partners, Inc.2,570$14.8K0.00%00.0%Unchanged
Legal & General Group Plc3,127$18.0K0.00%00.0%Unchanged
Citigroup Inc3,407$19.7K0.00%−106,253−96.9%Reduced
Amalgamated Bank3,506$20.0K0.00%−785−18.3%Reduced
Wells Fargo & Company5,994$34.6K0.00%+5,994New
Point72 Middle East FZE9,364$54.0K0.00%+9,364New
Point72 Asset Management, L.P.10,130$58.5K0.00%+10,130New
Quantbot Technologies LP10,853$62.6K0.00%+10,853New
Virtus ETF Advisers LLC11,396$65.8K0.04%−4,378−27.8%Reduced
Atom Investors LP11,890$68.6K0.04%+11,890New
California State Teachers Retirement System12,598$72.7K0.00%−929−6.9%Reduced
State Board of Administration of Florida Retirement System12,630$72.9K0.00%00.0%Unchanged
Occudo Quantitative Strategies LP12,652$73.0K0.01%+12,652New
Voya Investment Management LLC13,162$75.9K0.00%00.0%Unchanged
Schonfeld Strategic Advisors LLC13,400$77.3K0.00%+13,400New
Manufacturers Life Insurance Company, The13,627$78.6K0.00%00.0%Unchanged
SG Americas Securities, LLC15,040$87.0K0.00%+15,040New
Mirae Asset Global Investments Co., Ltd.15,512$89.5K0.00%−36−0.2%Reduced
American International Group, Inc.16,353$94.4K0.00%+326+2.0%Added
Barclays PLC17,217$99.3K0.00%−113,782−86.9%Reduced
New York State Common Retirement Fund17,634$101.7K0.00%−6,832−27.9%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.19,306$111.4K0.00%+2,617+15.7%Added
MetLife Investment Management22,045$127.2K0.00%00.0%Unchanged
Centiva Capital, LP23,572$136.0K0.01%+23,572New
Deutsche Bank AG24,856$143.4K0.00%+7,015+39.3%Added
JPMorgan Chase & Co25,956$150.0K0.00%+6,156+31.1%Added
Tudor Investment Corp Et Al27,639$159.0K0.00%+9,955+56.3%Added
Alliancebernstein L.P.31,200$180.0K0.00%+3,600+13.0%Added
State of Wisconsin Investment Board43,100$248.7K0.00%+43,100New
Verition Fund Management LLC44,180$254.9K0.00%+44,180New
Two Sigma Advisers, LP46,700$269.5K0.00%+46,700New
Trexquant Investment LP50,839$293.3K0.01%+50,839New
Rhumbline Advisers51,688$298.0K0.00%+72+0.1%Added
Bank of America Corp56,243$324.5K0.00%−239,617−81.0%Reduced
Jump Financial, LLC58,800$339.3K0.01%+28,400+93.4%Added
PDT Partners, LLC59,969$346.0K0.05%+59,969New
Morgan Stanley69,377$400.3K0.00%+27,953+67.5%Added
Dimensional Fund Advisors LP76,485$441.2K0.00%−77,635−50.4%Reduced
Gsa Capital Partners LLP97,900$565.0K0.06%+84,281+618.8%Added
Renaissance Technologies LLC101,751$587.0K0.00%+101,751New
Squarepoint Ops LLC109,214$630.2K0.00%+109,214New
D. E. Shaw & Co., Inc.111,298$642.2K0.00%+111,298New
Nuveen Asset Management, LLC115,800$668.0K0.00%+21,728+23.1%Added
Bank of New York Mellon Corp124,053$715.8K0.00%−2,431−1.9%Reduced
HRT Financial LP124,963$721.0K0.01%+124,963New
ExodusPoint Capital Management, LP156,138$901.0K0.01%+105,407+207.8%Added
Assenagon Asset Management S.A.168,215$970.6K0.00%+168,215New
Ergoteles LLC177,337$1.02M0.04%+177,337New
Cubist Systematic Strategies, LLC178,284$1.03M0.01%+68,981+63.1%Added
Two Sigma Investments, LP179,096$1.03M0.00%+144,003+410.3%Added
Marshall Wace, LLP180,919$1.04M0.00%+68,101+60.4%Added
Jane Street Group, LLC202,724$1.17M0.00%+202,724New
Charles Schwab Investment Management Inc230,347$1.33M0.00%−565−0.2%Reduced
Northern Trust Corp275,768$1.59M0.00%−3,362−1.2%Reduced
Goldman Sachs Group Inc300,624$1.73M0.00%+26,153+9.5%Added
Susquehanna International Group, LLP304,069$1.75M0.00%+279,613+1,143.3%Added
Rock Springs Capital Management LP460,391$2.66M0.06%00.0%Unchanged
Wellington Management Group LLP550,332$3.18M0.00%−192,408−25.9%Reduced
Baker Bros. Advisors LP626,884$3.62M0.02%−65,247−9.4%Reduced
Geode Capital Management, LLC633,008$3.65M0.00%+29,995+5.0%Added
State Street Corp711,528$4.11M0.00%−2,325,932−76.6%Reduced
Principal Financial Group Inc719,937$4.15M0.00%−62,772−8.0%Reduced
Millennium Management LLC790,213$4.56M0.01%+273,402+52.9%Added
Janus Henderson Group PLC843,718$4.87M0.00%−262,141−23.7%Reduced
FMR LLC957,903$5.53M0.00%−161,634−14.4%Reduced
Vanguard Group Inc1,283,043$7.40M0.00%−278,657−17.8%Reduced
Logos Global Management LP2,797,501$16.1M2.31%00.0%Unchanged
Citadel Advisors LLC2,865,167$16.5M0.02%+362,606+14.5%Added
Ra Capital Management, L.P.2,971,231$17.1M0.39%00.0%Unchanged
BlackRock Inc.3,185,891$18.4M0.00%−322,133−9.2%Reduced
Avoro Capital Advisors LLC3,500,000$20.2M0.30%+1,227,778+54.0%Added
Cormorant Asset Management, LP5,150,000$29.7M1.96%00.0%Unchanged
Sr One Capital Management, LP6,526,476$37.7M14.03%00.0%Unchanged
EcoR1 Capital, LLC0$00.00%−884,903−100.0%Sold out
Rafferty Asset Management, LLC0$00.00%−243,585−100.0%Sold out
Ghost Tree Capital, LLC0$00.00%−82,853−100.0%Sold out
Acadian Asset Management LLC0$00.00%−57,957−100.0%Sold out