Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Design Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 95
- +2 vs. Q2 2025
- Shares held
- 34.5M
- −37.9K (−0.1%) vs. Q2 2025
- Total value
- $259.7M
- +$143.4M (+123.2%) vs. Q2 2025
- New holders
- 14
- 17 more added
- Sold out
- 12
- 38 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital Advisors, Ltd. LLC | 12 | $0 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 3 | $23 | 0.00% | +3 | New |
| Versant Capital Management, Inc | 71 | $535 | 0.00% | +71 | New |
| Rise Advisors, LLC | 130 | $979 | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 100 | $1.00K | 0.00% | −250−71.4% | Reduced |
| SRS Capital Advisors, Inc. | 194 | $1.46K | 0.00% | +194 | New |
| EverSource Wealth Advisors, LLC | 235 | $1.77K | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 239 | $1.80K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 222 | $2.00K | 0.00% | −49−18.1% | Reduced |
| UMA Financial Services, Inc. | 268 | $2.02K | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 328 | $2.47K | 0.00% | +328 | New |
| Farther Finance Advisors, LLC | 385 | $2.90K | 0.00% | +366+1,926.3% | Added |
| GAMMA Investing LLC | 443 | $3.34K | 0.00% | +443 | New |
| Royal Bank of Canada | 445 | $4.00K | 0.00% | −3,367−88.3% | Reduced |
| Private Wealth Management Group, LLC | 558 | $4.20K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 610 | $4.59K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 1,176 | $9.00K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,213 | $9.13K | 0.00% | −236−16.3% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1,227 | $9.24K | 0.00% | −590−32.5% | Reduced |
| Citigroup Inc | 1,590 | $12.0K | 0.00% | −12,058−88.3% | Reduced |
| Sterling Capital Management LLC | 1,648 | $12.4K | 0.00% | +807+96.0% | Added |
| The PNC Financial Services Group, Inc. | 1,823 | $13.7K | 0.00% | +152+9.1% | Added |
| Tower Research Capital LLC (TRC) | 1,959 | $14.8K | 0.00% | −7,739−79.8% | Reduced |
| California State Teachers Retirement System | 1,969 | $14.8K | 0.00% | +1,969 | New |
| New York State Common Retirement Fund | 2,026 | $15.3K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 2,077 | $15.7K | 0.00% | −1,001−32.5% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,202 | $16.6K | 0.00% | +9+0.4% | Added |
| Ameritas Investment Partners, Inc. | 2,570 | $19.4K | 0.00% | 00.0% | Unchanged |
| Caz Investments LP | 5,000 | $37.6K | 0.07% | −2,500−33.3% | Reduced |
| BNP Paribas Arbitrage, SA | 5,133 | $38.7K | 0.00% | +1,310+34.3% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 5,702 | $42.9K | 0.01% | +5,702 | New |
| Russell Investments Group, Ltd. | 6,377 | $48.0K | 0.00% | +2,618+69.6% | Added |
| Police & Firemen's Retirement System of New Jersey | 6,598 | $49.7K | 0.00% | 00.0% | Unchanged |
| MetLife Investment Management | 10,320 | $77.7K | 0.00% | +10,320 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 10,724 | $80.8K | 0.00% | −7,233−40.3% | Reduced |
| Nisa Investment Advisors, LLC | 11,824 | $89.0K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 11,868 | $89.4K | 0.00% | +11,868 | New |
| AQR Capital Management LLC | 13,664 | $102.9K | 0.00% | −15,062−52.4% | Reduced |
| Susquehanna International Group, LLP | 14,023 | $105.6K | 0.00% | −24,147−63.3% | Reduced |
| Intech Investment Management LLC | 14,155 | $106.6K | 0.00% | −5,513−28.0% | Reduced |
| Invesco Ltd. | 14,589 | $109.9K | 0.00% | +225+1.6% | Added |
| Mariner, LLC | 16,081 | $121.1K | 0.00% | +341+2.2% | Added |
| Price T Rowe Associates Inc | 16,314 | $123.0K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 18,317 | $137.9K | 0.00% | −1,967−9.7% | Reduced |
| Velan Capital Investment Management LP | 20,000 | $150.6K | 0.14% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 21,918 | $165.0K | 0.04% | +21,918 | New |
| STRS Ohio | 22,600 | $170.2K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 22,693 | $170.9K | 0.00% | −4,649−17.0% | Reduced |
| JPMorgan Chase & Co | 23,221 | $174.9K | 0.00% | +4,896+26.7% | Added |
| Bank of America Corp | 23,907 | $180.0K | 0.00% | −718−2.9% | Reduced |
| State of Wisconsin Investment Board | 27,062 | $203.8K | 0.00% | −1,600−5.6% | Reduced |
| Kennedy Capital Management, Inc. | 29,411 | $221.5K | 0.00% | +14,401+95.9% | Added |
| HRT Financial LP | 31,903 | $240.0K | 0.00% | +31,903 | New |
| China Universal Asset Management Co., Ltd. | 34,982 | $263.4K | 0.02% | +23,580+206.8% | Added |
| Two Sigma Advisers, LP | 40,500 | $305.0K | 0.00% | −68,000−62.7% | Reduced |
| Prudential Financial Inc | 44,825 | $337.5K | 0.00% | −13,100−22.6% | Reduced |
| Alliancebernstein L.P. | 46,120 | $347.3K | 0.00% | +1,090+2.4% | Added |
| Rhumbline Advisers | 46,334 | $348.9K | 0.00% | −1,983−4.1% | Reduced |
| DLD Asset Management, LP | 50,000 | $376.5K | 0.05% | +50,000 | New |
| American Century Companies Inc | 50,852 | $382.9K | 0.00% | +4,467+9.6% | Added |
| Palumbo Wealth Management LLC | 52,081 | $392.2K | 0.13% | −8,474−14.0% | Reduced |
| Two Sigma Investments, LP | 59,237 | $446.1K | 0.00% | −30,074−33.7% | Reduced |
| Lynx1 Capital Management LP | 65,954 | $496.6K | 0.10% | 00.0% | Unchanged |
| Millennium Management LLC | 68,823 | $518.2K | 0.00% | +68,823 | New |
| Bank of New York Mellon Corp | 87,475 | $658.7K | 0.00% | −7,128−7.5% | Reduced |
| Barclays PLC | 88,176 | $664.0K | 0.00% | −21,360−19.5% | Reduced |
| Jane Street Group, LLC | 117,833 | $887.3K | 0.00% | +86,754+279.1% | Added |
| Nuveen, LLC | 133,028 | $1.00M | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 175,991 | $1.33M | 0.00% | −37,559−17.6% | Reduced |
| Bridgeway Capital Management, LLC | 188,200 | $1.42M | 0.03% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 247,934 | $1.87M | 0.00% | −3,015−1.2% | Reduced |
| Goldman Sachs Group Inc | 261,445 | $1.97M | 0.00% | +21,986+9.2% | Added |
| Renaissance Technologies LLC | 274,300 | $2.07M | 0.00% | +6,500+2.4% | Added |
| Dimensional Fund Advisors LP | 279,817 | $2.11M | 0.00% | −33,546−10.7% | Reduced |
| Northern Trust Corp | 296,529 | $2.23M | 0.00% | −65,989−18.2% | Reduced |
| D. E. Shaw & Co., Inc. | 373,276 | $2.81M | 0.00% | −17,372−4.4% | Reduced |
| Ra Capital Management, L.P. | 475,699 | $3.58M | 0.04% | +475,699 | New |
| Citadel Advisors LLC | 554,020 | $4.17M | 0.00% | −286,773−34.1% | Reduced |
| MPM Oncology Impact Management LP | 555,187 | $4.18M | 0.68% | 00.0% | Unchanged |
| Woodline Partners LP | 612,712 | $4.61M | 0.02% | −164,825−21.2% | Reduced |
| Acadian Asset Management LLC | 617,489 | $4.65M | 0.01% | −9,859−1.6% | Reduced |
| State Street Corp | 634,397 | $4.78M | 0.00% | −84,815−11.8% | Reduced |
| Geode Capital Management, LLC | 695,613 | $5.24M | 0.00% | −98,395−12.4% | Reduced |
| FMR LLC | 740,849 | $5.58M | 0.00% | −210,349−22.1% | Reduced |
| Kynam Capital Management, LP | 1,029,579 | $7.75M | 0.58% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 1,076,236 | $8.10M | 0.06% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,443,701 | $10.9M | 0.00% | −27,873−1.9% | Reduced |
| Almitas Capital LLC | 1,530,435 | $11.5M | 2.64% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 1,712,882 | $12.9M | 0.09% | 00.0% | Unchanged |
| Tang Capital Management LLC | 1,780,975 | $13.4M | 0.52% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 1,953,547 | $14.7M | 0.44% | 00.0% | Unchanged |
| BlackRock, Inc. | 2,044,388 | $15.4M | 0.00% | −351,355−14.7% | Reduced |
| Point72 Asset Management, L.P. | 3,340,552 | $25.2M | 0.05% | +1,533,334+84.8% | Added |
| Logos Global Management LP | 3,655,000 | $27.5M | 2.72% | −562,627−13.3% | Reduced |
| Sr One Capital Management, LP | 6,526,476 | $49.1M | 7.11% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −59,975−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −42,408−100.0% | Sold out |
| Assenagon Asset Management S.A. | 0 | $0 | 0.00% | −31,125−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −28,094−100.0% | Sold out |
| CI Private Wealth, LLC | 0 | $0 | 0.00% | −26,965−100.0% | Sold out |