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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Design Therapeutics, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
93
+5 vs. Q4 2023
Shares held
30.7M
−989.9K (−3.1%) vs. Q4 2023
Total value
$123.9M
+$39.8M (+47.4%) vs. Q4 2023
New holders
19
21 more added
Sold out
14
37 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 93 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ1 2024: $123.9M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q4 2023.

Institutions holding DSGN in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd32$00.00%−2−5.9%Reduced
CWM, LLC1$00.00%+1New
Capital Advisors, Ltd. LLC12$00.00%+12New
Zurcher Kantonalbank (Zurich Cantonalbank)1$40.00%00.0%Unchanged
Nelson, Van Denburg & Campbell Wealth Management Group, LLC7$280.00%+7New
Massmutual Trust Co FSB239$9630.00%+239New
Private Wealth Management Group, LLC558$2.25K0.00%+558New
Clearstead Advisors, LLC610$2.78K0.00%00.0%Unchanged
Royal Bank of Canada734$3.00K0.00%−10,065−93.2%Reduced
Amalgamated Bank1,176$5.00K0.00%−1,754−59.9%Reduced
Group One Trading, L.P.1,300$5.24K0.00%−100−7.1%Reduced
Quantbot Technologies LP1,705$6.87K0.00%00.0%Unchanged
New York State Common Retirement Fund2,026$8.16K0.00%00.0%Unchanged
Legal & General Group Plc2,565$10.3K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.2,570$10.4K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,677$10.8K0.00%−18,826−87.6%Reduced
California State Teachers Retirement System3,294$13.3K0.00%−2,100−38.9%Reduced
Russell Investments Group, Ltd.4,311$17.4K0.00%+2,447+131.3%Added
Simplex Trading, LLC5,019$20.0K0.00%+3,057+155.8%Added
Citigroup Inc6,329$25.5K0.00%+1,514+31.4%Added
ADAR1 Capital Management, LLC7,200$29.0K0.01%+5,200+260.0%Added
Federated Hermes, Inc.10,318$41.6K0.00%−1,681−14.0%Reduced
Invesco Ltd.10,474$42.2K0.00%−463−4.2%Reduced
The PNC Financial Services Group, Inc.10,843$43.7K0.00%+9,370+636.1%Added
Algert Global LLC11,080$44.7K0.00%−24,540−68.9%Reduced
Price T Rowe Associates Inc11,147$45.0K0.00%+11,147New
Susquehanna International Group, LLP11,232$45.3K0.00%−9,664−46.2%Reduced
SG Americas Securities, LLC11,316$46.0K0.00%−7,541−40.0%Reduced
Simplicity Wealth,LLC11,495$46.3K0.00%+11,495New
Bleakley Financial Group, LLC11,495$46.3K0.00%+11,495New
Wells Fargo & Company11,506$46.4K0.00%+1,484+14.8%Added
Nisa Investment Advisors, LLC11,560$46.6K0.00%00.0%Unchanged
AQR Capital Management LLC11,748$47.3K0.00%−44,492−79.1%Reduced
Principal Financial Group Inc12,497$50.4K0.00%−2,719−17.9%Reduced
Cubist Systematic Strategies, LLC13,384$53.9K0.00%−44,297−76.8%Reduced
XTX Topco Ltd15,257$61.5K0.01%+15,257New
American International Group, Inc.16,150$65.1K0.00%−139−0.9%Reduced
Palumbo Wealth Management LLC16,972$68.4K0.03%+16,972New
State Board of Administration of Florida Retirement System12,630$72.9K0.00%+12,630New
Mariner, LLC18,674$75.3K0.00%+18,674New
Mirae Asset Global Investments Co., Ltd.14,133$77.7K0.00%+14,133New
Occudo Quantitative Strategies LP23,395$94.3K0.02%+11,071+89.8%Added
Public Employees Retirement System of Ohio23,748$95.7K0.00%−2,590−9.8%Reduced
Tudor Investment Corp Et Al25,327$102.1K0.00%+25,327New
CI Private Wealth, LLC26,965$108.7K0.00%+26,965New
Deutsche Bank AG28,094$113.2K0.00%00.0%Unchanged
STRS Ohio29,300$118.0K0.00%−43,500−59.8%Reduced
UBS Group AG33,033$133.1K0.00%−17,408−34.5%Reduced
Squarepoint Ops LLC36,437$146.8K0.00%−1,992−5.2%Reduced
Dimensional Fund Advisors LP36,855$148.5K0.00%−4,993−11.9%Reduced
Alliancebernstein L.P.37,500$151.1K0.00%00.0%Unchanged
JPMorgan Chase & Co38,704$156.0K0.00%−2,556−6.2%Reduced
Bank of America Corp45,397$183.0K0.00%−40,941−47.4%Reduced
Prudential Financial Inc46,815$188.7K0.00%+28,400+154.2%Added
Prelude Capital Management, LLC48,600$195.9K0.01%00.0%Unchanged
HSBC Holdings PLC48,789$196.6K0.00%+3,734+8.3%Added
Ameriprise Financial Inc50,515$203.6K0.00%−2,500−4.7%Reduced
Rhumbline Advisers52,452$211.4K0.00%+1,588+3.1%Added
FMR LLC78,341$315.7K0.00%−671−0.8%Reduced
Barclays PLC88,908$358.3K0.00%−22,046−19.9%Reduced
Opaleye Management Inc.113,038$455.5K0.10%+113,038New
Bank of New York Mellon Corp115,242$464.4K0.00%−5,550−4.6%Reduced
Shay Capital LLC128,305$517.1K0.15%+128,305New
Bridgeway Capital Management, LLC145,900$588.0K0.01%00.0%Unchanged
Nuveen Asset Management, LLC158,004$636.8K0.00%00.0%Unchanged
Charles Schwab Investment Management Inc179,170$722.1K0.00%+3,525+2.0%Added
Walleye Capital LLC194,551$784.0K0.01%−167,836−46.3%Reduced
Wellington Management Group LLP214,310$863.7K0.00%+214,310New
Gsa Capital Partners LLP216,347$872.0K0.07%+144,055+199.3%Added
Prescott Group Capital Management, L.L.C.343,000$1.38M0.22%00.0%Unchanged
Assenagon Asset Management S.A.347,794$1.40M0.00%+102,567+41.8%Added
Northern Trust Corp357,284$1.44M0.00%−15,643−4.2%Reduced
Acadian Asset Management LLC403,546$1.63M0.01%+222,805+123.3%Added
Two Sigma Advisers, LP404,000$1.63M0.00%−181,000−30.9%Reduced
Two Sigma Investments, LP422,035$1.70M0.00%−6,136−1.4%Reduced
D. E. Shaw & Co., Inc.446,190$1.80M0.00%+155,562+53.5%Added
Renaissance Technologies LLC453,400$1.83M0.00%−195,400−30.1%Reduced
Morgan Stanley478,092$1.93M0.00%−65,389−12.0%Reduced
Millennium Management LLC484,468$1.95M0.00%+64,405+15.3%Added
Jacobs Levy Equity Management, Inc502,020$2.02M0.01%−47,098−8.6%Reduced
Goldman Sachs Group Inc506,256$2.04M0.00%−517,467−50.5%Reduced
Point72 Asset Management, L.P.593,516$2.39M0.01%+593,516New
Geode Capital Management, LLC683,898$2.76M0.00%+21,154+3.2%Added
State Street Corp698,986$2.82M0.00%+3,762+0.5%Added
Citadel Advisors LLC874,777$3.53M0.00%−957,477−52.3%Reduced
BML Capital Management, LLC879,478$3.54M2.37%−150,000−14.6%Reduced
Almitas Capital LLC1,026,068$4.14M1.71%00.0%Unchanged
Vanguard Group Inc1,285,962$5.18M0.00%+288,803+29.0%Added
Tang Capital Management LLC1,480,975$5.97M0.62%+3000.0%Added
Baker Bros. Advisors LP1,662,120$6.70M0.08%+162,120+10.8%Added
BlackRock Inc.2,274,191$9.16M0.00%−106,051−4.5%Reduced
Logos Global Management LP5,032,501$20.3M2.13%00.0%Unchanged
Sr One Capital Management, LP6,526,476$26.3M7.22%00.0%Unchanged
Prosight Management, LP0$00.00%−280,000−100.0%Sold out
Candriam Luxembourg S.C.A.0$00.00%−225,000−100.0%Sold out
Jane Street Group, LLC0$00.00%−54,693−100.0%Sold out
HRT Financial LP0$00.00%−40,718−100.0%Sold out
PDT Partners, LLC0$00.00%−28,401−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−22,569−100.0%Sold out
Engineers Gate Manager LP0$00.00%−17,914−100.0%Sold out