Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Taysha Gene Therapies, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 191
- +1 vs. Q4 2025
- Shares held
- 265.6M
- +12.1M (+4.8%) vs. Q4 2025
- Total value
- $1.18B
- −$211.2M (−15.1%) vs. Q4 2025
- New holders
- 35
- 69 more added
- Sold out
- 34
- 49 more reduced
5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Janus Henderson Group PLC | 69,000 | $308.1K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 80,779 | $361.1K | 0.00% | +13,302+19.7% | Added |
| Balyasny Asset Management LLC | 83,019 | $371.1K | 0.00% | +40,949+97.3% | Added |
| Vanguard Asset Management, Ltd | 90,474 | $404.4K | 0.00% | +90,474 | New |
| Manufacturers Life Insurance Company, The | 99,371 | $444.2K | 0.00% | +32,286+48.1% | Added |
| Legal & General Group Plc | 104,308 | $466.3K | 0.00% | −28,838−21.7% | Reduced |
| Franklin Resources Inc | 108,399 | $484.5K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 116,297 | $519.8K | 0.00% | −8,678−6.9% | Reduced |
| Vanguard Global Advisers, LLC | 116,691 | $521.6K | 0.00% | +116,691 | New |
| MetLife Investment Management | 120,116 | $536.9K | 0.00% | +6,850+6.0% | Added |
| BNP Paribas Arbitrage, SA | 120,200 | $537.3K | 0.00% | −52,282−30.3% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 124,730 | $549.0K | 0.00% | +2,091+1.7% | Added |
| Profund Advisors LLC | 134,671 | $602.0K | 0.02% | +6,081+4.7% | Added |
| California State Teachers Retirement System | 136,933 | $612.1K | 0.00% | −1,647−1.2% | Reduced |
| Tudor Investment Corp Et Al | 143,575 | $641.8K | 0.00% | +143,575 | New |
| Palumbo Wealth Management LLC | 146,709 | $655.8K | 0.16% | −31,298−17.6% | Reduced |
| Price T Rowe Associates Inc | 158,954 | $711.0K | 0.00% | +37,140+30.5% | Added |
| Wexford Capital LP | 160,654 | $718.1K | 0.12% | −20,199−11.2% | Reduced |
| AQR Capital Management LLC | 177,309 | $792.6K | 0.00% | +8,447+5.0% | Added |
| Deutsche Bank AG | 181,769 | $812.5K | 0.00% | +20,990+13.1% | Added |
| Privium Fund Management B.V. | 181,900 | $813.1K | 0.17% | +17,000+10.3% | Added |
| Panagora Asset Management Inc | 182,164 | $814.3K | 0.00% | +170,590+1,473.9% | Added |
| Wells Fargo & Company | 183,334 | $819.5K | 0.00% | −121,752−39.9% | Reduced |
| Victory Capital Management Inc | 195,745 | $875.0K | 0.00% | −190.0% | Reduced |
| Alps Advisors Inc | 222,986 | $996.7K | 0.00% | −1,934−0.9% | Reduced |
| Alliancebernstein L.P. | 189,240 | $1.04M | 0.00% | +9,600+5.3% | Added |
| Chicago Partners Investment Group LLC | 170,751 | $1.15M | 0.03% | +4,210+2.5% | Added |
| Superstring Capital Management LP | 258,269 | $1.15M | 0.82% | −722,499−73.7% | Reduced |
| Rhumbline Advisers | 258,530 | $1.16M | 0.00% | +1,090+0.4% | Added |
| State of Wisconsin Investment Board | 263,332 | $1.18M | 0.00% | +150,154+132.7% | Added |
| UBS Asset Management Americas Inc | 265,795 | $1.19M | 0.00% | +98,295+58.7% | Added |
| Swiss National Bank | 268,800 | $1.20M | 0.00% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 275,111 | $1.23M | 0.00% | 00.0% | Unchanged |
| Rafferty Asset Management, LLC | 299,903 | $1.34M | 0.01% | −44,881−13.0% | Reduced |
| Polen Capital Management LLC | 319,748 | $1.43M | 0.01% | +163,162+104.2% | Added |
| Moore Capital Management, LP | 328,831 | $1.47M | 0.05% | +328,831 | New |
| Invesco Ltd. | 368,021 | $1.65M | 0.00% | −964,759−72.4% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 391,476 | $1.75M | 0.06% | +83,019+26.9% | Added |
| Squarepoint Ops LLC | 410,282 | $1.83M | 0.00% | −61,295−13.0% | Reduced |
| Citadel Advisors LLC | 411,135 | $1.84M | 0.00% | −1,443,720−77.8% | Reduced |
| Renaissance Technologies LLC | 413,203 | $1.85M | 0.00% | +242,103+141.5% | Added |
| Acuta Capital Partners, LLC | 439,464 | $1.96M | 1.40% | −15,363−3.4% | Reduced |
| Point72 Asset Management, L.P. | 461,856 | $2.06M | 0.00% | −3,406,826−88.1% | Reduced |
| Jefferies Financial Group Inc. | 479,000 | $2.14M | 0.03% | +454,000+1,816.0% | Added |
| Dimensional Fund Advisors LP | 490,472 | $2.18M | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 511,983 | $2.29M | 0.00% | +293,798+134.7% | Added |
| Woodline Partners LP | 513,828 | $2.30M | 0.01% | +13,828+2.8% | Added |
| UBS Group AG | 517,698 | $2.31M | 0.00% | +134,655+35.2% | Added |
| Nuveen, LLC | 549,153 | $2.45M | 0.00% | +3,867+0.7% | Added |
| Bank of New York Mellon Corp | 608,123 | $2.72M | 0.00% | −16,244−2.6% | Reduced |
| Seven Fleet Capital Management LP | 625,708 | $2.80M | 0.88% | +458,485+274.2% | Added |
| Wellington Management Group LLP | 626,361 | $2.80M | 0.00% | −84,874−11.9% | Reduced |
| JPMorgan Chase & Co | 754,782 | $3.07M | 0.00% | −19,630−2.5% | Reduced |
| Sands Capital Ventures, LLC | 724,873 | $3.24M | 0.77% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 742,081 | $3.32M | 0.00% | +390,955+111.3% | Added |
| Quantum Private Wealth, LLC | 849,212 | $3.80M | 1.17% | +29,497+3.6% | Added |
| Granahan Investment Management Inc | 883,241 | $3.95M | 0.19% | +179,270+25.5% | Added |
| Affinity Asset Advisors, LLC | 1,000,000 | $4.47M | 0.26% | −2,300,000−69.7% | Reduced |
| Standard Life Aberdeen plc | 1,021,063 | $4.56M | 0.01% | 00.0% | Unchanged |
| Palo Alto Investors LP | 1,391,382 | $6.22M | 0.95% | +208,187+17.6% | Added |
| Vanguard Fiduciary Trust Co | 1,530,461 | $6.84M | 0.00% | +1,530,461 | New |
| Bank of America Corp | 1,677,046 | $7.50M | 0.00% | +524,366+45.5% | Added |
| B Group, Inc. | 1,800,556 | $8.05M | 5.97% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 1,808,599 | $8.08M | 0.00% | −94,379−5.0% | Reduced |
| Northern Trust Corp | 1,814,318 | $8.11M | 0.00% | +576,331+46.6% | Added |
| Rice Hall James & Associates, LLC | 1,944,671 | $8.69M | 0.48% | +674,026+53.0% | Added |
| Vanguard Portfolio Management LLC | 2,022,498 | $9.04M | 0.00% | +2,022,498 | New |
| SG Americas Securities, LLC | 2,176,742 | $9.73M | 0.01% | +1,395,268+178.5% | Added |
| Barclays PLC | 2,812,010 | $11.4M | 0.00% | −2,726,991−49.2% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 2,722,165 | $12.2M | 0.14% | 00.0% | Unchanged |
| Healthcare of Ontario Pension Plan Trust Fund | 2,883,301 | $12.9M | 0.02% | −838,699−22.5% | Reduced |
| ADAR1 Capital Management, LLC | 2,979,429 | $13.3M | 0.80% | +483,620+19.4% | Added |
| Casdin Capital, LLC | 3,250,000 | $14.5M | 1.10% | +1,750,000+116.7% | Added |
| Millennium Management LLC | 3,281,820 | $14.7M | 0.01% | +102,957+3.2% | Added |
| Baker Bros. Advisors LP | 4,004,756 | $17.9M | 0.10% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 4,427,301 | $19.8M | 0.02% | +413,666+10.3% | Added |
| Geode Capital Management, LLC | 5,531,955 | $24.7M | 0.00% | +144,929+2.7% | Added |
| Polar Capital Holdings Plc | 5,654,340 | $25.3M | 0.11% | −2,277,063−28.7% | Reduced |
| Siren, L.L.C. | 8,829,913 | $39.5M | 1.09% | −1,300,000−12.8% | Reduced |
| Octagon Capital Advisors LP | 8,859,911 | $39.6M | 4.38% | 00.0% | Unchanged |
| Vanguard Capital Management LLC | 10,231,502 | $45.7M | 0.00% | +10,231,502 | New |
| State Street Corp | 11,209,078 | $50.1M | 0.00% | +418,994+3.9% | Added |
| RTW Investments, LP | 13,680,248 | $61.2M | 0.61% | −2,718,049−16.6% | Reduced |
| FMR LLC | 14,321,255 | $64.0M | 0.00% | +792,889+5.9% | Added |
| Morgan Stanley | 17,965,371 | $80.3M | 0.00% | −113,147−0.6% | Reduced |
| Vestal Point Capital, LP | 18,000,000 | $80.5M | 2.25% | +4,250,000+30.9% | Added |
| BlackRock, Inc. | 18,365,608 | $82.1M | 0.00% | −277,521−1.5% | Reduced |
| Avoro Capital Advisors LLC | 21,700,000 | $97.0M | 0.96% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 22,369,645 | $100.0M | 0.01% | +8,676,906+63.4% | Added |
| Ra Capital Management, L.P. | 23,555,648 | $105.3M | 1.12% | 00.0% | Unchanged |
| GordonMD Global Investments LP | 737,550 | – | – | −593,351−44.6% | Reduced |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −1,328,000−100.0% | Sold out |
| EAM Investors, LLC | 0 | $0 | 0.00% | −823,758−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −457,132−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −409,254−100.0% | Sold out |
| Sphera Funds Management Ltd. | 0 | $0 | 0.00% | −368,146−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −309,481−100.0% | Sold out |
| Capricorn Fund Managers Ltd | 0 | $0 | 0.00% | −300,000−100.0% | Sold out |
| Colony Group, LLC | 0 | $0 | 0.00% | −295,516−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −288,535−100.0% | Sold out |