Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Taysha Gene Therapies, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 195
- +42 vs. Q3 2025
- Shares held
- 269.0M
- +8.09M (+3.1%) vs. Q3 2025
- Total value
- $1.48B
- +$625.8M (+73.3%) vs. Q3 2025
- New holders
- 64
- 62 more added
- Sold out
- 22
- 46 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Zurcher Kantonalbank (Zurich Cantonalbank) | 67,477 | $371.1K | 0.00% | +67,477 | New |
| Manufacturers Life Insurance Company, The | 67,085 | $369.0K | 0.00% | −2,772−4.0% | Reduced |
| Red Reef Advisors LLC | 65,950 | $362.7K | 0.37% | +65,950 | New |
| Creative Planning | 63,235 | $347.8K | 0.00% | +11,009+21.1% | Added |
| Citigroup Inc | 63,015 | $346.6K | 0.00% | +29,520+88.1% | Added |
| Police & Firemen's Retirement System of New Jersey | 57,168 | $314.4K | 0.00% | 00.0% | Unchanged |
| SummitTX Capital, L.P. | 56,595 | $311.3K | 0.01% | +56,595 | New |
| Commonwealth Equity Services, LLC | 55,657 | $306.1K | 0.00% | −2,600−4.5% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 57,975 | $304.4K | 0.00% | −22,757−28.2% | Reduced |
| Abacus Wealth Partners, LLC | 55,173 | $303.5K | 0.03% | +55,173 | New |
| Voloridge Investment Management, LLC | 54,785 | $301.3K | 0.00% | +54,785 | New |
| NBC Securities, Inc. | 52,955 | $291.3K | 0.02% | +52,955 | New |
| ProShare Advisors LLC | 52,463 | $288.5K | 0.00% | +6,424+14.0% | Added |
| SEI Investments Co | 47,858 | $263.2K | 0.00% | +47,858 | New |
| Militia Capital Partners, LP | 46,500 | $255.8K | 0.10% | −20,300−30.4% | Reduced |
| Virtus Investment Advisers, Inc. | 45,946 | $252.7K | 0.07% | +3,008+7.0% | Added |
| Williams & Novak, LLC | 45,000 | $247.5K | 0.19% | 00.0% | Unchanged |
| Redwood Wealth Management Group, LLC | 44,700 | $245.8K | 0.10% | +44,700 | New |
| China Universal Asset Management Co., Ltd. | 44,635 | $245.5K | 0.02% | −3,182−6.7% | Reduced |
| Group One Trading, L.P. | 44,195 | $243.1K | 0.01% | +42,441+2,419.7% | Added |
| First Manhattan Co | 43,500 | $239.3K | 0.00% | +15,000+52.6% | Added |
| Allianz Asset Management GmbH | 42,400 | $233.2K | 0.00% | +42,400 | New |
| Balyasny Asset Management LLC | 42,070 | $231.4K | 0.00% | +42,070 | New |
| Axq Capital, LP | 37,804 | $207.9K | 0.05% | −11,873−23.9% | Reduced |
| Arizona State Retirement System | 37,677 | $207.2K | 0.00% | +37,677 | New |
| J. Goldman & Co LP | 33,750 | $185.6K | 0.01% | +33,750 | New |
| Los Angeles Capital Management LLC | 32,918 | $161.6K | 0.00% | +32,918 | New |
| KLP Kapitalforvaltning AS | 29,300 | $161.2K | 0.00% | +29,300 | New |
| Leonteq Securities AG | 27,999 | $154.0K | 0.01% | 00.0% | Unchanged |
| Allegheny Financial Group LTD | 26,350 | $144.9K | 0.02% | +11,350+75.7% | Added |
| Caitong International Asset Management Co., Ltd | 25,577 | $140.7K | 0.03% | +22,373+698.3% | Added |
| Jefferies Financial Group Inc. | 25,000 | $137.5K | 0.00% | −2,131,642−98.8% | Reduced |
| Ethic Inc. | 22,735 | $125.0K | 0.00% | −3,049−11.8% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 22,080 | $121.0K | 0.00% | −1,610−6.8% | Reduced |
| Cetera Investment Advisers | 21,154 | $116.3K | 0.00% | +4,992+30.9% | Added |
| Mangrove Partners | 20,546 | $113.0K | 0.01% | +20,546 | New |
| Envestnet Asset Management Inc | 20,178 | $111.0K | 0.00% | +20,178 | New |
| Lee Financial Co | 20,000 | $110.0K | 0.01% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 19,837 | $109.1K | 0.00% | +19,837 | New |
| Simplex Trading, LLC | 19,782 | $108.8K | 0.00% | +17,060+626.7% | Added |
| Pictet Asset Management Holding SA | 19,318 | $106.2K | 0.00% | +19,318 | New |
| Scientech Research LLC | 18,176 | $100.0K | 0.06% | +18,176 | New |
| Raymond James Financial Inc | 18,144 | $99.8K | 0.00% | +18,144 | New |
| Ameritas Investment Partners, Inc. | 17,672 | $97.2K | 0.00% | +2,000+12.8% | Added |
| Xponance, Inc. | 17,218 | $94.7K | 0.00% | +643+3.9% | Added |
| Russell Investments Group, Ltd. | 16,929 | $93.1K | 0.00% | −1,236−6.8% | Reduced |
| Captrust Financial Advisors | 15,113 | $83.1K | 0.00% | +15,113 | New |
| Legato Capital Management LLC | 15,023 | $82.6K | 0.01% | +15,023 | New |
| CIBC World Markets Corp | 14,612 | $80.4K | 0.00% | +14,612 | New |
| Bank of Montreal | 13,708 | $75.4K | 0.00% | +40+0.3% | Added |
| Mackenzie Financial Corp | 13,308 | $75.2K | 0.00% | +2,094+18.7% | Added |
| Mirae Asset Global Investments Co., Ltd. | 13,311 | $73.2K | 0.00% | +2,765+26.2% | Added |
| CWM, LLC | 13,093 | $72.0K | 0.00% | +208+1.6% | Added |
| Principal Financial Group Inc | 12,823 | $70.5K | 0.00% | −3,428−21.1% | Reduced |
| CIBC Asset Management Inc | 11,959 | $65.8K | 0.00% | +11,959 | New |
| Panagora Asset Management Inc | 11,574 | $63.7K | 0.00% | +11,574 | New |
| Guggenheim Capital LLC | 11,111 | $61.1K | 0.00% | +11,111 | New |
| Oppenheimer Asset Management Inc. | 10,773 | $59.3K | 0.00% | +10,773 | New |
| Capital Investment Advisors, LLC | 10,000 | $55.0K | 0.00% | 00.0% | Unchanged |
| St Germain D J Co Inc | 9,633 | $53.0K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 6,939 | $38.0K | 0.00% | +1,405+25.4% | Added |
| Royal Bank of Canada | 6,302 | $34.0K | 0.00% | −577,073−98.9% | Reduced |
| Nisa Investment Advisors, LLC | 5,512 | $30.3K | 0.00% | −360−6.1% | Reduced |
| GF Fund Management Co. Ltd. | 5,383 | $29.6K | 0.00% | −486−8.3% | Reduced |
| Rockefeller Capital Management L.P. | 5,000 | $27.5K | 0.00% | 00.0% | Unchanged |
| Chung Wu Investment Group, LLC | 4,000 | $22.0K | 0.02% | +4,000 | New |
| International Assets Investment Management, LLC | 2,000 | $11.0K | 0.00% | +2,000 | New |
| Sterling Capital Management LLC | 1,411 | $7.76K | 0.00% | +896+174.0% | Added |
| The PNC Financial Services Group, Inc. | 1,054 | $5.80K | 0.00% | −254−19.4% | Reduced |
| Optiver Holding B.V. | 934 | $5.14K | 0.00% | −1,335−58.8% | Reduced |
| US Bancorp | 912 | $5.02K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 691 | $4.00K | 0.00% | −21,129−96.8% | Reduced |
| Tower Research Capital LLC (TRC) | 475 | $2.61K | 0.00% | −6,132−92.8% | Reduced |
| Essential Partners LLC | 327 | $1.80K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 280 | $1.54K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 277 | $1.53K | 0.00% | +143+106.7% | Added |
| GAMMA Investing LLC | 276 | $1.52K | 0.00% | +276 | New |
| Sound Income Strategies, LLC | 325 | $1.48K | 0.00% | +325 | New |
| Allworth Financial LP | 223 | $1.23K | 0.00% | +8+3.7% | Added |
| EverSource Wealth Advisors, LLC | 91 | $501 | 0.00% | 00.0% | Unchanged |
| Bare Financial Services, Inc | 85 | $468 | 0.00% | +85 | New |
| Rothschild Investment LLC | 70 | $385 | 0.00% | +70 | New |
| Signaturefd, LLC | 60 | $330 | 0.00% | +60 | New |
| Farther Finance Advisors, LLC | 55 | $303 | 0.00% | 00.0% | Unchanged |
| SageView Advisory Group, LLC | 49 | $270 | 0.00% | +49 | New |
| True Wealth Design, LLC | 30 | $165 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 21 | $116 | 0.00% | +21 | New |
| Tradewinds Capital Management, LLC | 20 | $110 | 0.00% | +20 | New |
| SBI Securities Co., Ltd. | 15 | $83 | 0.00% | −1−6.3% | Reduced |
| IFP Advisors, Inc | 14 | $77 | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 8 | $44 | 0.00% | +8 | New |
| Northwestern Mutual Wealth Management Co | 8 | $44 | 0.00% | +8 | New |
| Assetmark, Inc | 8 | $44 | 0.00% | +8 | New |
| Hughes Financial Services, LLC | 4 | $22 | 0.00% | +4 | New |
| Capital Advisors, Ltd. LLC | 77 | – | – | −2−2.5% | Reduced |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −1,923,962−100.0% | Sold out |
| Great Point Partners LLC | 0 | $0 | 0.00% | −1,500,000−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −900,000−100.0% | Sold out |
| Alphabet Inc. | 0 | $0 | 0.00% | −640,882−100.0% | Sold out |
| Anson Funds Management LP | 0 | $0 | 0.00% | −603,500−100.0% | Sold out |