Skip to main content
Livermore
Livermore
ZHEN

Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Taysha Gene Therapies, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of TSHA: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders1552195+42
Shares264.6M3.72M269.0M+8.09M (+3.1%)
Value$865.6M$12.2M$1.48B+$625.8M (+73.3%)

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (64)

Institutions that held Taysha Gene Therapies, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to TSHA in Q4 2025
InstitutionSharesValue% of portfolio
Healthcare of Ontario Pension Plan Trust Fund3,722,000$20.5M0.03%
Norges Bank1,837,800$10.1M0.00%
Casdin Capital, LLC1,500,000$8.25M0.51%
GordonMD Global Investments LP1,330,901$7.32M5.25%
Standard Life Aberdeen plc1,021,063$5.62M0.01%
Superstring Capital Management LP980,768$5.39M2.89%
EAM Investors, LLC823,758$4.53M0.50%
HRT Financial LP409,254$2.25M0.01%
Hennion & Walsh Asset Management, Inc.308,457$1.70M0.06%
Capricorn Fund Managers Ltd300,000$1.65M0.40%
Colony Group, LLC295,516$1.63M0.00%
Ensign Peak Advisors, Inc275,111$1.51M0.00%
Swiss National Bank268,800$1.48M0.00%
Oracle Investment Management Inc265,000$1.46M0.96%
Nomura Holdings Inc259,339$1.43M0.00%
Alps Advisors Inc224,920$1.24M0.01%
Renaissance Technologies LLC171,100$941.0K0.00%
UBS Asset Management Americas Inc167,500$921.3K0.00%
Seven Fleet Capital Management LP167,223$919.7K0.62%
Polen Capital Management LLC156,586$861.2K0.00%
Two Sigma Advisers, LP139,581$767.7K0.00%
Canada Pension Plan Investment Board68,900$378.9K0.00%
Janus Henderson Group PLC69,000$378.5K0.00%
Zurcher Kantonalbank (Zurich Cantonalbank)67,477$371.1K0.00%
Red Reef Advisors LLC65,950$362.7K0.37%
SummitTX Capital, L.P.56,595$311.3K0.01%
Abacus Wealth Partners, LLC55,173$303.5K0.03%
Voloridge Investment Management, LLC54,785$301.3K0.00%
NBC Securities, Inc.52,955$291.3K0.02%
SEI Investments Co47,858$263.2K0.00%
Redwood Wealth Management Group, LLC44,700$245.8K0.10%
Allianz Asset Management GmbH42,400$233.2K0.00%
Balyasny Asset Management LLC42,070$231.4K0.00%
Arizona State Retirement System37,677$207.2K0.00%
J. Goldman & Co LP33,750$185.6K0.01%
Los Angeles Capital Management LLC32,918$161.6K0.00%
KLP Kapitalforvaltning AS29,300$161.2K0.00%
Mangrove Partners20,546$113.0K0.01%
Envestnet Asset Management Inc20,178$111.0K0.00%
Teacher Retirement System of Texas19,837$109.1K0.00%
Pictet Asset Management Holding SA19,318$106.2K0.00%
Scientech Research LLC18,176$100.0K0.06%
Raymond James Financial Inc18,144$99.8K0.00%
Captrust Financial Advisors15,113$83.1K0.00%
Legato Capital Management LLC15,023$82.6K0.01%
CIBC World Markets Corp14,612$80.4K0.00%
CIBC Asset Management Inc11,959$65.8K0.00%
Panagora Asset Management Inc11,574$63.7K0.00%
Guggenheim Capital LLC11,111$61.1K0.00%
Oppenheimer Asset Management Inc.10,773$59.3K0.00%
Chung Wu Investment Group, LLC4,000$22.0K0.02%
International Assets Investment Management, LLC2,000$11.0K0.00%
GAMMA Investing LLC276$1.52K0.00%
Sound Income Strategies, LLC325$1.48K0.00%
Bare Financial Services, Inc85$4680.00%
Rothschild Investment LLC70$3850.00%
Signaturefd, LLC60$3300.00%
SageView Advisory Group, LLC49$2700.00%
SRS Capital Advisors, Inc.21$1160.00%
Tradewinds Capital Management, LLC20$1100.00%
MAI Capital Management8$440.00%
Northwestern Mutual Wealth Management Co8$440.00%
Assetmark, Inc8$440.00%
Hughes Financial Services, LLC4$220.00%

Sold out (22)

Institutions that held Taysha Gene Therapies, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of TSHA in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Toronto Dominion Bank1,923,962$6.29M
Great Point Partners LLC1,500,000$4.91M
Tang Capital Management LLC900,000$2.94M
Alphabet Inc.640,882$2.10M
Anson Funds Management LP603,500$1.97M
Marshall Wace, LLP476,865$1.56M
Kovitz Investment Group Partners, LLC298,667$976.6K
Readystate Asset Management LP161,972$529.6K
Engineers Gate Manager LP53,483$174.9K
Jain Global LLC52,608$172.0K
Virtu Financial LLC48,123$157.0K
Quadrature Capital Ltd47,328$154.3K
Brevan Howard Capital Management LP46,643$152.5K
Sender Co & Partners, Inc.27,121$88.7K
DRW Securities, LLC16,389$53.3K
R Squared Ltd16,094$52.6K
Arrowpoint Investment Partners (Singapore) Pte. Ltd.12,200$39.9K
Aigen Investment Management, LP10,367$33.9K
FNY Investment Advisers, LLC4,289$14.0K
Aster Capital Management (DIFC) Ltd1,280$4.19K
Clearstead Advisors, LLC690$2.26K
Morton Brown Family Wealth, LLC260$850

Not filed for Q4 2025 yet (2)

Institutions that held Taysha Gene Therapies, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding TSHA in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Tybourne Capital Management (HK) Ltd3,700,000$12.1M
CIBC Bancorp USA Inc.22,643$74.0K