Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Taysha Gene Therapies, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 195
- +42 vs. Q3 2025
- Shares held
- 269.0M
- +8.09M (+3.1%) vs. Q3 2025
- Total value
- $1.48B
- +$625.8M (+73.3%) vs. Q3 2025
- New holders
- 64
- 62 more added
- Sold out
- 22
- 46 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Hughes Financial Services, LLC | 4 | $22 | 0.00% | +4 | New |
| MAI Capital Management | 8 | $44 | 0.00% | +8 | New |
| Northwestern Mutual Wealth Management Co | 8 | $44 | 0.00% | +8 | New |
| Assetmark, Inc | 8 | $44 | 0.00% | +8 | New |
| IFP Advisors, Inc | 14 | $77 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 15 | $83 | 0.00% | −1−6.3% | Reduced |
| Tradewinds Capital Management, LLC | 20 | $110 | 0.00% | +20 | New |
| SRS Capital Advisors, Inc. | 21 | $116 | 0.00% | +21 | New |
| True Wealth Design, LLC | 30 | $165 | 0.00% | 00.0% | Unchanged |
| SageView Advisory Group, LLC | 49 | $270 | 0.00% | +49 | New |
| Farther Finance Advisors, LLC | 55 | $303 | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 60 | $330 | 0.00% | +60 | New |
| Rothschild Investment LLC | 70 | $385 | 0.00% | +70 | New |
| Bare Financial Services, Inc | 85 | $468 | 0.00% | +85 | New |
| EverSource Wealth Advisors, LLC | 91 | $501 | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 223 | $1.23K | 0.00% | +8+3.7% | Added |
| Sound Income Strategies, LLC | 325 | $1.48K | 0.00% | +325 | New |
| GAMMA Investing LLC | 276 | $1.52K | 0.00% | +276 | New |
| Advisor Group Holdings, Inc. | 277 | $1.53K | 0.00% | +143+106.7% | Added |
| Parallel Advisors, LLC | 280 | $1.54K | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 327 | $1.80K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 475 | $2.61K | 0.00% | −6,132−92.8% | Reduced |
| Daiwa Securities Group Inc. | 691 | $4.00K | 0.00% | −21,129−96.8% | Reduced |
| US Bancorp | 912 | $5.02K | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 934 | $5.14K | 0.00% | −1,335−58.8% | Reduced |
| The PNC Financial Services Group, Inc. | 1,054 | $5.80K | 0.00% | −254−19.4% | Reduced |
| Sterling Capital Management LLC | 1,411 | $7.76K | 0.00% | +896+174.0% | Added |
| International Assets Investment Management, LLC | 2,000 | $11.0K | 0.00% | +2,000 | New |
| Chung Wu Investment Group, LLC | 4,000 | $22.0K | 0.02% | +4,000 | New |
| Rockefeller Capital Management L.P. | 5,000 | $27.5K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 5,383 | $29.6K | 0.00% | −486−8.3% | Reduced |
| Nisa Investment Advisors, LLC | 5,512 | $30.3K | 0.00% | −360−6.1% | Reduced |
| Royal Bank of Canada | 6,302 | $34.0K | 0.00% | −577,073−98.9% | Reduced |
| Amalgamated Bank | 6,939 | $38.0K | 0.00% | +1,405+25.4% | Added |
| St Germain D J Co Inc | 9,633 | $53.0K | 0.00% | 00.0% | Unchanged |
| Capital Investment Advisors, LLC | 10,000 | $55.0K | 0.00% | 00.0% | Unchanged |
| Oppenheimer Asset Management Inc. | 10,773 | $59.3K | 0.00% | +10,773 | New |
| Guggenheim Capital LLC | 11,111 | $61.1K | 0.00% | +11,111 | New |
| Panagora Asset Management Inc | 11,574 | $63.7K | 0.00% | +11,574 | New |
| CIBC Asset Management Inc | 11,959 | $65.8K | 0.00% | +11,959 | New |
| Principal Financial Group Inc | 12,823 | $70.5K | 0.00% | −3,428−21.1% | Reduced |
| CWM, LLC | 13,093 | $72.0K | 0.00% | +208+1.6% | Added |
| Mirae Asset Global Investments Co., Ltd. | 13,311 | $73.2K | 0.00% | +2,765+26.2% | Added |
| Mackenzie Financial Corp | 13,308 | $75.2K | 0.00% | +2,094+18.7% | Added |
| Bank of Montreal | 13,708 | $75.4K | 0.00% | +40+0.3% | Added |
| CIBC World Markets Corp | 14,612 | $80.4K | 0.00% | +14,612 | New |
| Legato Capital Management LLC | 15,023 | $82.6K | 0.01% | +15,023 | New |
| Captrust Financial Advisors | 15,113 | $83.1K | 0.00% | +15,113 | New |
| Russell Investments Group, Ltd. | 16,929 | $93.1K | 0.00% | −1,236−6.8% | Reduced |
| Xponance, Inc. | 17,218 | $94.7K | 0.00% | +643+3.9% | Added |
| Ameritas Investment Partners, Inc. | 17,672 | $97.2K | 0.00% | +2,000+12.8% | Added |
| Raymond James Financial Inc | 18,144 | $99.8K | 0.00% | +18,144 | New |
| Scientech Research LLC | 18,176 | $100.0K | 0.06% | +18,176 | New |
| Pictet Asset Management Holding SA | 19,318 | $106.2K | 0.00% | +19,318 | New |
| Simplex Trading, LLC | 19,782 | $108.8K | 0.00% | +17,060+626.7% | Added |
| Teacher Retirement System of Texas | 19,837 | $109.1K | 0.00% | +19,837 | New |
| Lee Financial Co | 20,000 | $110.0K | 0.01% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 20,178 | $111.0K | 0.00% | +20,178 | New |
| Mangrove Partners | 20,546 | $113.0K | 0.01% | +20,546 | New |
| Cetera Investment Advisers | 21,154 | $116.3K | 0.00% | +4,992+30.9% | Added |
| Cambridge Investment Research Advisors, Inc. | 22,080 | $121.0K | 0.00% | −1,610−6.8% | Reduced |
| Ethic Inc. | 22,735 | $125.0K | 0.00% | −3,049−11.8% | Reduced |
| Jefferies Financial Group Inc. | 25,000 | $137.5K | 0.00% | −2,131,642−98.8% | Reduced |
| Caitong International Asset Management Co., Ltd | 25,577 | $140.7K | 0.03% | +22,373+698.3% | Added |
| Allegheny Financial Group LTD | 26,350 | $144.9K | 0.02% | +11,350+75.7% | Added |
| Leonteq Securities AG | 27,999 | $154.0K | 0.01% | 00.0% | Unchanged |
| KLP Kapitalforvaltning AS | 29,300 | $161.2K | 0.00% | +29,300 | New |
| Los Angeles Capital Management LLC | 32,918 | $161.6K | 0.00% | +32,918 | New |
| J. Goldman & Co LP | 33,750 | $185.6K | 0.01% | +33,750 | New |
| Arizona State Retirement System | 37,677 | $207.2K | 0.00% | +37,677 | New |
| Axq Capital, LP | 37,804 | $207.9K | 0.05% | −11,873−23.9% | Reduced |
| Balyasny Asset Management LLC | 42,070 | $231.4K | 0.00% | +42,070 | New |
| Allianz Asset Management GmbH | 42,400 | $233.2K | 0.00% | +42,400 | New |
| First Manhattan Co | 43,500 | $239.3K | 0.00% | +15,000+52.6% | Added |
| Group One Trading, L.P. | 44,195 | $243.1K | 0.01% | +42,441+2,419.7% | Added |
| China Universal Asset Management Co., Ltd. | 44,635 | $245.5K | 0.02% | −3,182−6.7% | Reduced |
| Redwood Wealth Management Group, LLC | 44,700 | $245.8K | 0.10% | +44,700 | New |
| Williams & Novak, LLC | 45,000 | $247.5K | 0.19% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 45,946 | $252.7K | 0.07% | +3,008+7.0% | Added |
| Militia Capital Partners, LP | 46,500 | $255.8K | 0.10% | −20,300−30.4% | Reduced |
| SEI Investments Co | 47,858 | $263.2K | 0.00% | +47,858 | New |
| ProShare Advisors LLC | 52,463 | $288.5K | 0.00% | +6,424+14.0% | Added |
| NBC Securities, Inc. | 52,955 | $291.3K | 0.02% | +52,955 | New |
| Voloridge Investment Management, LLC | 54,785 | $301.3K | 0.00% | +54,785 | New |
| Abacus Wealth Partners, LLC | 55,173 | $303.5K | 0.03% | +55,173 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 57,975 | $304.4K | 0.00% | −22,757−28.2% | Reduced |
| Commonwealth Equity Services, LLC | 55,657 | $306.1K | 0.00% | −2,600−4.5% | Reduced |
| SummitTX Capital, L.P. | 56,595 | $311.3K | 0.01% | +56,595 | New |
| Police & Firemen's Retirement System of New Jersey | 57,168 | $314.4K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 63,015 | $346.6K | 0.00% | +29,520+88.1% | Added |
| Creative Planning | 63,235 | $347.8K | 0.00% | +11,009+21.1% | Added |
| Red Reef Advisors LLC | 65,950 | $362.7K | 0.37% | +65,950 | New |
| Manufacturers Life Insurance Company, The | 67,085 | $369.0K | 0.00% | −2,772−4.0% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 67,477 | $371.1K | 0.00% | +67,477 | New |
| New York State Common Retirement Fund | 67,500 | $371.3K | 0.00% | −100−0.1% | Reduced |
| Janus Henderson Group PLC | 69,000 | $378.5K | 0.00% | +69,000 | New |
| Canada Pension Plan Investment Board | 68,900 | $378.9K | 0.00% | +68,900 | New |
| Intech Investment Management LLC | 71,069 | $390.9K | 0.00% | +2,443+3.6% | Added |
| Prudential Financial Inc | 86,730 | $477.0K | 0.00% | +58,385+206.0% | Added |
| Franklin Resources Inc | 108,399 | $596.2K | 0.00% | 00.0% | Unchanged |