Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Taysha Gene Therapies, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 131
- +13 vs. Q3 2024
- Shares held
- 167.5M
- +12.6M (+8.2%) vs. Q3 2024
- Total value
- $289.8M
- −$21.5M (−6.9%) vs. Q3 2024
- New holders
- 28
- 44 more added
- Sold out
- 15
- 28 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alphabet Inc. | 640,882 | $1.11M | 0.06% | 00.0% | Unchanged |
| Sands Capital Ventures, LLC | 724,873 | $1.25M | 0.27% | 00.0% | Unchanged |
| Citadel Advisors LLC | 745,205 | $1.29M | 0.00% | −2,114,767−73.9% | Reduced |
| Quantum Private Wealth, LLC | 794,976 | $1.38M | 0.44% | +27,360+3.6% | Added |
| Palo Alto Investors LP | 811,268 | $1.40M | 0.22% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 878,448 | $1.52M | 0.00% | +878,448 | New |
| Acuta Capital Partners, LLC | 884,244 | $1.53M | 1.54% | −1,234,748−58.3% | Reduced |
| B Group, Inc. | 965,556 | $1.67M | 1.02% | +965,556 | New |
| Goldman Sachs Group Inc | 967,144 | $1.67M | 0.00% | −238,527−19.8% | Reduced |
| Woodline Partners LP | 1,027,522 | $1.78M | 0.01% | +280.0% | Added |
| Northern Trust Corp | 1,458,732 | $2.52M | 0.00% | +86,207+6.3% | Added |
| Norges Bank | 1,461,120 | $2.53M | 0.00% | +1,461,120 | New |
| Granahan Investment Management Inc | 1,636,381 | $2.83M | 0.12% | +496,482+43.6% | Added |
| Bank of America Corp | 1,710,303 | $2.96M | 0.00% | +1,576,568+1,178.9% | Added |
| JPMorgan Chase & Co | 2,643,755 | $4.57M | 0.00% | −357,642−11.9% | Reduced |
| Polar Capital Holdings Plc | 3,000,000 | $5.19M | 0.03% | −25,000−0.8% | Reduced |
| VR Adviser, LLC | 3,225,180 | $5.58M | 0.38% | −5,774,820−64.2% | Reduced |
| Geode Capital Management, LLC | 3,572,349 | $6.18M | 0.00% | +9,591+0.3% | Added |
| Tybourne Capital Management (HK) Ltd | 3,700,000 | $6.40M | 1.61% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 4,004,756 | $6.93M | 0.07% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 5,000,000 | $8.65M | 0.02% | +5,000,000 | New |
| State Street Corp | 6,474,367 | $11.2M | 0.00% | +3,005,299+86.6% | Added |
| Siren, L.L.C. | 6,602,475 | $11.4M | 0.50% | +1,722,600+35.3% | Added |
| RTW Investments, LP | 8,672,630 | $15.0M | 0.23% | −6,273,790−42.0% | Reduced |
| Vanguard Group Inc | 8,906,764 | $15.4M | 0.00% | +641,305+7.8% | Added |
| Octagon Capital Advisors LP | 10,450,000 | $18.1M | 3.08% | +5,877,778+128.6% | Added |
| Ra Capital Management, L.P. | 10,872,503 | $18.8M | 0.25% | 00.0% | Unchanged |
| BlackRock, Inc. | 13,531,467 | $23.4M | 0.00% | +10,934+0.1% | Added |
| FMR LLC | 16,365,664 | $28.3M | 0.00% | −2,312,863−12.4% | Reduced |
| Morgan Stanley | 17,640,366 | $30.5M | 0.00% | +9,976,373+130.2% | Added |
| Avoro Capital Advisors LLC | 19,999,999 | $34.6M | 0.49% | +1,349,999+7.2% | Added |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −843,200−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −352,684−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −233,560−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −100,795−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −73,857−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −68,264−100.0% | Sold out |
| SEI Investments Co | 0 | $0 | 0.00% | −39,188−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −38,813−100.0% | Sold out |
| Nebula Research & Development LLC | 0 | $0 | 0.00% | −21,737−100.0% | Sold out |
| Aigen Investment Management, LP | 0 | $0 | 0.00% | −11,189−100.0% | Sold out |
| Oliver Lagore Vanvalin Investment Group | 0 | $0 | 0.00% | −2,800−100.0% | Sold out |
| Global Retirement Partners, LLC | 0 | $0 | 0.00% | −1,006−100.0% | Sold out |
| Clear Street Markets LLC | 0 | $0 | 0.00% | −424−100.0% | Sold out |
| Riggs Asset Managment Co. Inc. | 0 | $0 | 0.00% | −198−100.0% | Sold out |
| International Assets Investment Management, LLC | 0 | $0 | 0.00% | −4,020−100.0% | Sold out |
| Ghost Tree Capital, LLC | – | – | – | – | Not filed |