Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 285
- +10 vs. Q4 2025
- Shares held
- 73.6M
- +6.99M (+10.5%) vs. Q4 2025
- Total value
- $6.42B
- −$704.3M (−9.9%) vs. Q4 2025
- New holders
- 63
- 102 more added
- Sold out
- 53
- 89 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Jump Financial, LLC | 0 | $0 | 0.00% | −6,759−100.0% | Sold out |
| Legato Capital Management LLC | 0 | $0 | 0.00% | −5,723−100.0% | Sold out |
| Quantedge Capital Pte Ltd | 0 | $0 | 0.00% | −5,600−100.0% | Sold out |
| Voleon Capital Management LP | 0 | $0 | 0.00% | −5,025−100.0% | Sold out |
| PSP Research LLC | 0 | $0 | 0.00% | −4,738−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −4,614−100.0% | Sold out |
| Vestmark Advisory Solutions, Inc. | 0 | $0 | 0.00% | −4,560−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −4,504−100.0% | Sold out |
| Mackenzie Financial Corp | 0 | $0 | 0.00% | −4,398−100.0% | Sold out |
| Empowered Funds, LLC | 0 | $0 | 0.00% | −4,164−100.0% | Sold out |
| O'Shaughnessy Asset Management, LLC | 0 | $0 | 0.00% | −3,580−100.0% | Sold out |
| Toroso Investments, LLC | 0 | $0 | 0.00% | −3,336−100.0% | Sold out |
| Keybank National Association | 0 | $0 | 0.00% | −3,271−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −3,225−100.0% | Sold out |
| Yorktown Management & Research Co Inc | 0 | $0 | 0.00% | −3,050−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −2,900−100.0% | Sold out |
| JGP Global Gestao de Recursos Ltda. | 0 | $0 | 0.00% | −2,866−100.0% | Sold out |
| AlphaGrep UK Ltd | 0 | $0 | 0.00% | −2,509−100.0% | Sold out |
| State of Wyoming | 0 | $0 | 0.00% | −2,441−100.0% | Sold out |
| M&T Bank Corp | 0 | $0 | 0.00% | −2,101−100.0% | Sold out |
| Cambria Investment Management, L.P. | 0 | $0 | 0.00% | −1,997−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −1,960−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −1,663−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −1,508−100.0% | Sold out |
| Persistent Asset Partners Ltd | 0 | $0 | 0.00% | −1,446−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −1,246−100.0% | Sold out |
| CFG Wealth Management Services, Inc. | 0 | $0 | 0.00% | −800−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −201−100.0% | Sold out |
| AdvisorNet Financial, Inc | 0 | $0 | 0.00% | −137−100.0% | Sold out |
| Bayforest Capital Ltd | 0 | $0 | 0.00% | −134−100.0% | Sold out |
| Quarry LP | 0 | $0 | 0.00% | −77−100.0% | Sold out |
| SageView Advisory Group, LLC | 0 | $0 | 0.00% | −30−100.0% | Sold out |
| Rakuten Securities, Inc. | 0 | $0 | 0.00% | −15−100.0% | Sold out |
| SJS Investment Consulting Inc. | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Rialto Wealth Management, LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| TD Private Client Wealth LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Dunhill Financial, LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Avion Wealth | 0 | $0 | 0.00% | −4−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Norges Bank | – | – | – | – | Not filed |
| Comerica Bank | – | – | – | – | Not filed |
| CIBC World Markets Corp | – | – | – | – | Not filed |
| Global Retirement Partners, LLC | – | – | – | – | Not filed |
| ORG Partners LLC | – | – | – | – | Not filed |