Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 281
- +19 vs. Q3 2025
- Shares held
- 72.9M
- +2.01M (+2.8%) vs. Q3 2025
- Total value
- $7.80B
- +$602.5M (+8.4%) vs. Q3 2025
- New holders
- 58
- 107 more added
- Sold out
- 39
- 89 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avion Wealth | 4 | $0 | 0.00% | +4 | New |
| Dunhill Financial, LLC | 1 | $65 | 0.00% | +1 | New |
| TD Private Client Wealth LLC | 1 | $107 | 0.00% | +1 | New |
| Bay Harbor Wealth Management, LLC | 1 | $107 | 0.00% | +1 | New |
| Rialto Wealth Management, LLC | 1 | $108 | 0.00% | +1 | New |
| MAI Capital Management | 2 | $215 | 0.00% | −1,855−99.9% | Reduced |
| SJS Investment Consulting Inc. | 2 | $215 | 0.00% | +2 | New |
| HFM Investment Advisors, LLC | 2 | $215 | 0.00% | +2 | New |
| DiNuzzo Private Wealth, Inc. | 3 | $322 | 0.00% | +3 | New |
| Toronto Dominion Bank | 6 | $642 | 0.00% | +6 | New |
| Fortitude Family Office, LLC | 6 | $642 | 0.00% | +6 | New |
| Keating Financial Advisory Services, Inc. | 9 | $963 | 0.00% | +9 | New |
| JFS Wealth Advisors, LLC | 10 | $1.07K | 0.00% | +10 | New |
| CVA Family Office, LLC | 12 | $1.28K | 0.00% | 00.0% | Unchanged |
| Rakuten Securities, Inc. | 15 | $1.61K | 0.00% | +15 | New |
| UMA Financial Services, Inc. | 16 | $1.71K | 0.00% | 00.0% | Unchanged |
| Bare Financial Services, Inc | 22 | $2.35K | 0.00% | +4+22.2% | Added |
| Parallel Advisors, LLC | 25 | $2.68K | 0.00% | 00.0% | Unchanged |
| First Horizon Corp | 30 | $3.21K | 0.00% | +30 | New |
| SageView Advisory Group, LLC | 30 | $3.21K | 0.00% | +30 | New |
| Parkside Financial Bank & Trust | 33 | $3.53K | 0.00% | 00.0% | Unchanged |
| Versant Capital Management, Inc | 36 | $3.85K | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 36 | $3.85K | 0.00% | +17+89.5% | Added |
| ORG Partners LLC | 37 | $3.96K | 0.00% | +5+15.6% | Added |
| Root Financial Partners, LLC | 43 | $4.60K | 0.00% | +43 | New |
| Eastern Bank | 59 | $6.32K | 0.00% | +59 | New |
| WPG Advisers, LLC | 60 | $6.42K | 0.00% | +3+5.3% | Added |
| Harbour Investments, Inc. | 60 | $6.42K | 0.00% | +60 | New |
| Bessemer Group Inc | 66 | $7.00K | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 77 | $8.24K | 0.00% | +49+175.0% | Added |
| Quarry LP | 77 | $8.24K | 0.00% | +77 | New |
| Rothschild Investment LLC | 91 | $9.74K | 0.00% | +6+7.1% | Added |
| Optiver Holding B.V. | 92 | $9.85K | 0.00% | −273−74.8% | Reduced |
| Allworth Financial LP | 109 | $11.7K | 0.00% | −22−16.8% | Reduced |
| Basecamp Wealth Advisors LLC | 125 | $13.4K | 0.00% | +125 | New |
| Bayforest Capital Ltd | 134 | $14.3K | 0.01% | −1,037−88.6% | Reduced |
| AdvisorNet Financial, Inc | 137 | $14.7K | 0.00% | +32+30.5% | Added |
| Truvestments Capital LLC | 138 | $14.8K | 0.00% | 00.0% | Unchanged |
| True Wealth Design, LLC | 147 | $15.7K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 201 | $22.0K | 0.00% | −12−5.6% | Reduced |
| Kemnay Advisory Services Inc. | 207 | $22.2K | 0.00% | +207 | New |
| Essential Partners LLC | 223 | $23.9K | 0.01% | +25+12.6% | Added |
| Jones Financial Companies LLLP | 231 | $24.7K | 0.00% | −3−1.3% | Reduced |
| Signaturefd, LLC | 232 | $24.8K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 266 | $28.5K | 0.00% | +200+303.0% | Added |
| SBI Securities Co., Ltd. | 343 | $36.7K | 0.00% | +145+73.2% | Added |
| Sterling Capital Management LLC | 344 | $36.8K | 0.00% | +217+170.9% | Added |
| GAMMA Investing LLC | 361 | $38.6K | 0.00% | +118+48.6% | Added |
| SRS Capital Advisors, Inc. | 381 | $40.8K | 0.00% | −400−51.2% | Reduced |
| Smartleaf Asset Management LLC | 399 | $42.6K | 0.00% | +113+39.5% | Added |
| Covestor Ltd | 579 | $62.0K | 0.03% | +444+328.9% | Added |
| Farther Finance Advisors, LLC | 642 | $68.7K | 0.00% | +291+82.9% | Added |
| CFG Wealth Management Services, Inc. | 800 | $85.6K | 0.08% | +800 | New |
| Global Retirement Partners, LLC | 857 | $91.7K | 0.00% | +457+114.3% | Added |
| US Bancorp | 953 | $102.0K | 0.00% | +807+552.7% | Added |
| Advisor Group Holdings, Inc. | 1,039 | $111.2K | 0.00% | +59+6.0% | Added |
| Danske Bank A/S | 1,100 | $117.7K | 0.00% | +1,100 | New |
| Clearstead Advisors, LLC | 1,246 | $133.4K | 0.00% | +847+212.3% | Added |
| GF Fund Management Co. Ltd. | 1,310 | $140.2K | 0.00% | −119−8.3% | Reduced |
| Persistent Asset Partners Ltd | 1,446 | $154.8K | 0.07% | +1,446 | New |
| Quest Partners LLC | 1,508 | $161.4K | 0.01% | +117+8.4% | Added |
| Amalgamated Bank | 1,663 | $178.0K | 0.00% | −30−1.8% | Reduced |
| Royal Bank of Canada | 1,676 | $180.0K | 0.00% | −124,110−98.7% | Reduced |
| Whittier Trust Co | 1,811 | $180.1K | 0.00% | 00.0% | Unchanged |
| KBC Group NV | 1,707 | $183.0K | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 1,960 | $209.8K | 0.00% | −1,008−34.0% | Reduced |
| ZRC Wealth Management, LLC | 1,971 | $211.0K | 0.07% | 00.0% | Unchanged |
| Cambria Investment Management, L.P. | 1,997 | $213.8K | 0.01% | +1,997 | New |
| M&T Bank Corp | 2,101 | $224.9K | 0.00% | +2,101 | New |
| Abel Hall, LLC | 2,140 | $229.1K | 0.05% | +2,140 | New |
| JustInvest LLC | 2,379 | $254.6K | 0.00% | +311+15.0% | Added |
| Centaurus Financial, Inc. | 2,389 | $256.0K | 0.01% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2,415 | $259.0K | 0.00% | +1,918+385.9% | Added |
| State of Wyoming | 2,441 | $261.3K | 0.03% | +1,487+155.9% | Added |
| Entropy Technologies, LP | 2,492 | $266.7K | 0.01% | −6,010−70.7% | Reduced |
| AlphaGrep UK Ltd | 2,509 | $268.6K | 0.09% | +2,509 | New |
| Chicago Partners Investment Group LLC | 2,739 | $281.8K | 0.01% | +284+11.6% | Added |
| Swiss Life Asset Management Ltd | 2,653 | $284.0K | 0.00% | +192+7.8% | Added |
| CWM, LLC | 2,767 | $296.0K | 0.00% | −125−4.3% | Reduced |
| CIBC Asset Management Inc | 2,848 | $304.9K | 0.00% | +2,848 | New |
| JGP Global Gestao de Recursos Ltda. | 2,866 | $306.8K | 0.18% | −387−11.9% | Reduced |
| Blueshift Asset Management, LLC | 2,881 | $308.4K | 0.09% | +2,881 | New |
| Two Sigma Advisers, LP | 2,900 | $310.4K | 0.00% | −400−12.1% | Reduced |
| Tower Research Capital LLC (TRC) | 2,962 | $317.1K | 0.01% | +1,209+69.0% | Added |
| Cim Investment Mangement Inc | 2,993 | $320.4K | 0.08% | 00.0% | Unchanged |
| Yorktown Management & Research Co Inc | 3,050 | $326.5K | 0.26% | +3,050 | New |
| Cinctive Capital Management LP | 3,225 | $345.2K | 0.02% | −31,931−90.8% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 3,243 | $347.1K | 0.00% | +675+26.3% | Added |
| Keybank National Association | 3,271 | $350.1K | 0.00% | +3,271 | New |
| Toroso Investments, LLC | 3,336 | $357.1K | 0.00% | +672+25.2% | Added |
| CIBC World Markets Corp | 3,502 | $374.9K | 0.00% | +3,502 | New |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 3,572 | $382.3K | 0.01% | +31+0.9% | Added |
| O'Shaughnessy Asset Management, LLC | 3,580 | $383.2K | 0.00% | −1,256−26.0% | Reduced |
| Cerity Partners LLC | 3,664 | $392.2K | 0.00% | +700+23.6% | Added |
| Freestone Capital Holdings, LLC | 3,700 | $396.0K | 0.01% | 00.0% | Unchanged |
| Quantinno Capital Management LP | 3,831 | $410.1K | 0.00% | +1,273+49.8% | Added |
| Ensign Peak Advisors, Inc | 3,859 | $413.1K | 0.00% | −107,685−96.5% | Reduced |
| Comerica Bank | 4,014 | $429.6K | 0.00% | −205,311−98.1% | Reduced |
| Susquehanna International Group, LLP | 4,097 | $438.5K | 0.00% | +993+32.0% | Added |
| Empowered Funds, LLC | 4,164 | $445.7K | 0.01% | +2,019+94.1% | Added |