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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2022

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
111
+13 vs. Q4 2021
Shares held
48.9M
+401.3K (+0.8%) vs. Q4 2021
Total value
$562.7M
+$79.1M (+16.4%) vs. Q4 2021
New holders
22
32 more added
Sold out
9
37 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 111 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ1 2022: $562.7M
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2021.

Institutions holding RYTM in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Rock Springs Capital Management LP1,237,026$14.3M0.36%+609,846+97.2%Added
Franklin Resources Inc1,779,454$20.5M0.01%+242,582+15.8%Added
Vanguard Group Inc2,257,020$26.0M0.00%−66,501−2.9%Reduced
Janus Henderson Group PLC2,951,002$34.0M0.02%−182,933−5.8%Reduced
BlackRock Inc.3,284,105$37.8M0.00%−43,956−1.3%Reduced
Goldman Sachs Group Inc3,339,750$38.5M0.01%+243,202+7.9%Added
Baker Bros. Advisors LP4,125,062$47.5M0.27%+261,823+6.8%Added
Ra Capital Management, L.P.4,871,067$56.1M1.22%00.0%Unchanged
NEA Management Company, LLC4,912,306$56.6M1.83%00.0%Unchanged
Federated Hermes, Inc.5,065,113$58.4M0.13%+2,261,778+80.7%Added
Primecap Management Co6,291,991$72.5M0.05%+35,000+0.6%Added
Rafferty Asset Management, LLC0$00.00%−111,594−100.0%Sold out
Norges Bank0$00.00%−51,161−100.0%Sold out
Prudential Financial Inc0$00.00%−46,400−100.0%Sold out
Engineers Gate Manager LP0$00.00%−20,633−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−15,475−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−14,661−100.0%Sold out
Group One Trading, L.P.0$00.00%−241−100.0%Sold out
Ellevest, Inc.0$00.00%−10−100.0%Sold out
Parallel Advisors, LLC0$00.00%−50−100.0%Sold out