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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2021

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
97
−8 vs. Q2 2021
Shares held
48.0M
+470.2K (+1.0%) vs. Q2 2021
Total value
$626.3M
−$279.3M (−30.8%) vs. Q2 2021
New holders
7
29 more added
Sold out
15
35 more reduced

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 97 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ3 2021: $626.3M
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q2 2021.

Institutions holding RYTM in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Captrust Financial Advisors19$00.00%−12−38.7%Reduced
US Bancorp96$1.00K0.00%−40−29.4%Reduced
Newbridge Financial Services Group, Inc.65$1.00K0.00%00.0%Unchanged
Geneos Wealth Management Inc.200$2.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.172$2.00K0.00%+74+75.5%Added
Parallel Advisors, LLC181$2.00K0.00%+181New
Group One Trading, L.P.241$3.00K0.00%−733−75.3%Reduced
Evolution Wealth Advisors, LLC213$3.00K0.00%−325−60.4%Reduced
State of Wyoming219$3.00K0.00%−73−25.0%Reduced
Bessemer Group Inc251$3.00K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.350$5.00K0.00%−9−2.5%Reduced
Nisa Investment Advisors, LLC550$7.00K0.00%00.0%Unchanged
FourThought Financial, LLC570$7.00K0.00%+570New
Advisor Group Holdings, Inc.810$11.0K0.00%−105−11.5%Reduced
Koshinski Asset Management, Inc.1,060$13.8K0.00%+1,060New
Penserra Capital Management LLC1,145$14.0K0.00%00.0%Unchanged
Signaturefd, LLC1,964$26.0K0.00%+1,464+292.8%Added
Wells Fargo & Company2,213$29.0K0.00%−7,558−77.4%Reduced
Great West Life Assurance Co2,363$31.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)3,197$41.0K0.00%−538−14.4%Reduced
Ameritas Investment Partners, Inc.3,454$45.0K0.00%00.0%Unchanged
Sierra Capital LLC3,600$47.0K0.01%00.0%Unchanged
Royal Bank of Canada4,580$60.0K0.00%+363+8.6%Added
Zurcher Kantonalbank (Zurich Cantonalbank)5,571$73.0K0.00%00.0%Unchanged
Hantz Financial Services, Inc.5,883$77.0K0.00%+5,883New
Simplex Trading, LLC4,404$91.0K0.00%−800−15.4%Reduced
Macquarie Group Ltd7,691$100.0K0.00%+5,761+298.5%Added
Metropolitan Life Insurance Co8,793$114.8K0.00%−3,657−29.4%Reduced
AQR Capital Management LLC10,191$133.0K0.00%+10,191New
Virtus ETF Advisers LLC10,229$134.0K0.06%−536−5.0%Reduced
BNP Paribas Arbitrage, SA10,908$142.5K0.00%+5,611+105.9%Added
ExodusPoint Capital Management, LP11,601$152.0K0.00%−3,343−22.4%Reduced
DekaBank Deutsche Girozentrale12,000$157.0K0.00%00.0%Unchanged
Legal & General Group Plc13,263$173.0K0.00%+6,811+105.6%Added
State Board of Administration of Florida Retirement System13,844$181.0K0.00%00.0%Unchanged
MetLife Investment Management15,372$200.8K0.00%00.0%Unchanged
Qube Research & Technologies Ltd15,453$202.0K0.00%−7,771−33.5%Reduced
ProShare Advisors LLC16,375$214.0K0.00%−4,075−19.9%Reduced
Price T Rowe Associates Inc16,712$218.0K0.00%00.0%Unchanged
Voya Investment Management LLC17,259$225.0K0.00%00.0%Unchanged
Parametric Portfolio Associates LLC18,850$246.0K0.00%−6,405−25.4%Reduced
Two Sigma Investments, LP22,306$291.0K0.00%−34,772−60.9%Reduced
JPMorgan Chase & Co22,501$293.0K0.00%+332+1.5%Added
Prudential Financial Inc22,752$297.0K0.00%−8,221−26.5%Reduced
Winton Group Ltd24,048$314.0K0.02%+7,185+42.6%Added
American International Group, Inc.24,111$315.0K0.00%−573−2.3%Reduced
Manufacturers Life Insurance Company, The24,423$319.0K0.00%−1,285−5.0%Reduced
UBS Asset Management Americas Inc25,215$329.3K0.00%00.0%Unchanged
Credit Suisse AG25,580$335.0K0.00%+1,778+7.5%Added
Deutsche Bank AG26,639$348.0K0.00%−3,237−10.8%Reduced
Invesco Ltd.27,333$357.0K0.00%+2,025+8.0%Added
ACT Capital Management, LLC31,000$405.0K0.21%00.0%Unchanged
New York State Common Retirement Fund35,165$459.0K0.00%−4,942−12.3%Reduced
Barclays PLC35,294$461.0K0.00%+16,806+90.9%Added
Alliancebernstein L.P.41,600$543.0K0.00%00.0%Unchanged
State of Wisconsin Investment Board48,400$632.0K0.00%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.48,950$639.0K0.03%+16,757+52.1%Added
Walleye Capital LLC49,845$651.0K0.02%+49,845New
Norges Bank51,161$668.0K0.00%00.0%Unchanged
California State Teachers Retirement System52,492$686.0K0.00%−8,247−13.6%Reduced
Susquehanna International Group, LLP53,203$695.0K0.00%+9,668+22.2%Added
Citigroup Inc59,726$780.0K0.00%−72,173−54.7%Reduced
Rhumbline Advisers61,287$800.0K0.00%+275+0.5%Added
Swiss National Bank77,700$1.01M0.00%+1,700+2.2%Added
UBS Group AG80,970$1.06M0.00%+851+1.1%Added
Rafferty Asset Management, LLC82,854$1.08M0.01%−167−0.2%Reduced
FMR LLC83,278$1.09M0.00%00.0%Unchanged
SG Americas Securities, LLC109,303$1.43M0.01%+27,435+33.5%Added
Stifel Financial Corp134,586$1.76M0.00%−46,828−25.8%Reduced
Rice Hall James & Associates, LLC149,720$1.96M0.07%+5,726+4.0%Added
Bank of New York Mellon Corp156,423$2.04M0.00%+16,391+11.7%Added
Franklin Resources Inc168,083$2.19M0.00%+168,083New
Dimensional Fund Advisors LP180,445$2.36M0.00%−109,825−37.8%Reduced
Bank of America Corp204,463$2.67M0.00%+84,785+70.8%Added
Morgan Stanley205,466$2.68M0.00%−241,140−54.0%Reduced
Nuveen Asset Management, LLC213,982$2.79M0.00%−36,274−14.5%Reduced
Millennium Management LLC216,924$2.83M0.00%+60,108+38.3%Added
Charles Schwab Investment Management Inc266,362$3.48M0.00%−1,269−0.5%Reduced
Samsara BioCapital, LLC300,293$3.92M0.65%00.0%Unchanged
Northern Trust Corp420,434$5.49M0.00%−20,252−4.6%Reduced
Assenagon Asset Management S.A.502,270$6.56M0.03%+359,798+252.5%Added
Rock Springs Capital Management LP612,180$8.00M0.17%+5,900+1.0%Added
Geode Capital Management, LLC667,658$8.72M0.00%−17,245−2.5%Reduced
Wellington Management Group LLP845,952$11.0M0.00%−450,129−34.7%Reduced
MPM Asset Management LLC909,258$11.9M2.75%00.0%Unchanged
Gilder Gagnon Howe & Co LLC1,496,424$19.5M0.10%+7,301+0.5%Added
Deerfield Management Company, L.P. (Series C)1,989,625$26.0M0.51%00.0%Unchanged
State Street Corp2,224,717$29.1M0.00%+45,630+2.1%Added
Vanguard Group Inc2,313,078$30.2M0.00%+55,656+2.5%Added
Goldman Sachs Group Inc2,905,319$37.9M0.01%+1,837,108+172.0%Added
Federated Hermes, Inc.3,011,053$39.3M0.07%−4,158−0.1%Reduced
Janus Henderson Group PLC3,182,382$41.6M0.02%−743,668−18.9%Reduced
BlackRock Inc.3,361,986$43.9M0.00%+26,325+0.8%Added
Baker Bros. Advisors LP3,863,239$50.5M0.22%00.0%Unchanged
Ra Capital Management, L.P.4,871,067$63.6M0.88%00.0%Unchanged
NEA Management Company, LLC4,912,306$64.2M0.80%00.0%Unchanged
Primecap Management Co6,181,091$80.7M0.06%+27,400+0.4%Added
Bank of Montreal0$00.00%−151,446−100.0%Sold out
Altium Capital Management LP0$00.00%−104,840−100.0%Sold out
Caas Capital Management LP0$00.00%−84,044−100.0%Sold out