Prelude Therapeutics Inc
PRLD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001678660
No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.
13F holders, Q3 2026
Institutional positions in Prelude Therapeutics Inc as of Sep 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
Q3 2026 data is still coming in (13F filing deadline: Nov 16, 2026), so these numbers are incomplete.
- Institutional holders
- 59
- +15 vs. Q2 2026
- Shares held
- 12.2M
- +3.95M (+48.0%) vs. Q2 2026
- Total value
- $47.7M
- +$3.77M (+8.6%) vs. Q2 2026
- New holders
- 16
- 21 more added
- Sold out
- 1
- 15 more reduced
31 institutions that held it in Q2 2026 haven't filed for Q3 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 75 | $264.3M |
| Q1 2026 | 55 | $105.2M |
| Q4 2025 | 48 | $82.6M |
| Q3 2025 | 47 | $39.1M |
| Q2 2025 | 50 | $22.0M |
| Q1 2025 | 59 | $23.3M |
| Q4 2024 | 62 | $41.0M |
| Q3 2024 | 70 | $74.0M |
| Q2 2024 | 61 | $129.2M |
| Q1 2024 | 58 | $162.1M |
| Q4 2023 | 56 | $148.3M |
| Q3 2023 | 60 | $113.1M |
| Q2 2023 | 55 | $176.2M |
| Q1 2023 | 55 | $179.6M |
| Q4 2022 | 60 | $188.3M |
| Q3 2022 | 53 | $210.3M |
| Q2 2022 | 62 | $170.9M |
| Q1 2022 | 68 | $235.4M |
| Q4 2021 | 75 | $437.6M |
| Q3 2021 | 61 | $1.12B |
| Q2 2021 | 57 | $986.6M |
| Q1 2021 | 60 | $1.41B |
Institutions, Q3 2026
Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q2 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Affinity Asset Advisors, LLC | 2,600,000 | $10.2M | 0.58% | +2,600,000 | New |
| Vanguard Capital Management LLC | 1,897,370 | $7.42M | 0.00% | −112,075−5.6% | Reduced |
| BlackRock, Inc. | 1,857,602 | $7.26M | 0.00% | +60,101+3.3% | Added |
| Acadian Asset Management LLC | 842,984 | $3.29M | 0.00% | +231,625+37.9% | Added |
| Geode Capital Management, LLC | 717,361 | $2.81M | 0.00% | −124,501−14.8% | Reduced |
| State Street Corp | 662,923 | $2.59M | 0.00% | +234,136+54.6% | Added |
| UBS Group AG | 556,530 | $2.18M | 0.00% | +237,733+74.6% | Added |
| Morgan Stanley | 520,095 | $2.03M | 0.00% | +16,235+3.2% | Added |
| Renaissance Technologies LLC | 297,709 | $1.16M | 0.00% | +16,509+5.9% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 266,674 | $1.04M | 0.00% | +141,068+112.3% | Added |
| Vanguard Fiduciary Trust Co | 235,757 | $921.8K | 0.00% | −49,129−17.2% | Reduced |
| Vanguard Portfolio Management LLC | 192,536 | $752.8K | 0.00% | −1,384−0.7% | Reduced |
| Qube Research & Technologies Ltd | 150,921 | $590.1K | 0.00% | +137,811+1,051.2% | Added |
| Marshall Wace, LLP | 142,819 | $558.4K | 0.00% | −47,873−25.1% | Reduced |
| Squarepoint Ops LLC | 140,882 | $550.8K | 0.00% | +81,342+136.6% | Added |
| HRT Financial LP | 137,536 | $537.0K | 0.00% | +137,536 | New |
| Arrowstreet Capital, Limited Partnership | 106,741 | $417.4K | 0.00% | +106,741 | New |
| Dimensional Fund Advisors LP | 89,041 | $348.5K | 0.00% | +53,831+152.9% | Added |
| Bank of New York Mellon Corp | 68,187 | $266.6K | 0.00% | 00.0% | Unchanged |
| Hillsdale Investment Management Inc. | 65,400 | $255.7K | 0.01% | −16,000−19.7% | Reduced |
| Rhumbline Advisers | 62,323 | $243.7K | 0.00% | +40,249+182.3% | Added |
| Integrated Quantitative Investments LLC | 60,677 | $237.2K | 0.04% | +60,677 | New |
| Empowered Funds, LLC | 59,978 | $234.5K | 0.00% | +59,978 | New |
| Panagora Asset Management Inc | 47,160 | $184.4K | 0.00% | −414−0.9% | Reduced |
| Nuveen, LLC | 37,023 | $144.8K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 35,658 | $139.4K | 0.00% | +916+2.6% | Added |
| JPMorgan Chase & Co | 33,836 | $134.0K | 0.00% | +20,298+149.9% | Added |
| FMR LLC | 26,658 | $104.2K | 0.00% | +21,029+373.6% | Added |
| Deutsche Bank AG | 24,449 | $95.6K | 0.00% | −3,375−12.1% | Reduced |
| Cerity Partners LLC | 23,501 | $91.9K | 0.00% | −9,374−28.5% | Reduced |
| Fox Run Management, L.L.C. | 23,226 | $90.8K | 0.01% | +23,226 | New |
| American Century Companies Inc | 21,870 | $85.5K | 0.00% | +21,870 | New |
| Spark Investment Management LLC | 20,400 | $79.8K | 0.13% | +9,800+92.5% | Added |
| Winton Group Ltd | 19,500 | $76.2K | 0.00% | +19,500 | New |
| Barclays PLC | 19,363 | $75.7K | 0.00% | +4,834+33.3% | Added |
| EntryPoint Capital, LLC | 16,456 | $64.3K | 0.02% | +16,456 | New |
| Axq Capital, LP | 16,133 | $63.1K | 0.01% | +16,133 | New |
| Polymer Capital Management (US) LLC | 14,092 | $55.1K | 0.01% | +14,092 | New |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 12,841 | $50.2K | 0.00% | +12,841 | New |
| Police & Firemen's Retirement System of New Jersey | 10,492 | $41.0K | 0.00% | 00.0% | Unchanged |
| Vanguard Global Advisers, LLC | 9,828 | $38.4K | 0.00% | −6,382−39.4% | Reduced |
| Advisor Group Holdings, Inc. | 9,000 | $35.2K | 0.00% | +9,000 | New |
| STRS Ohio | 7,700 | $30.1K | 0.00% | +2,200+40.0% | Added |
| BNP Paribas Arbitrage, SA | 6,665 | $26.1K | 0.00% | +2,561+62.4% | Added |
| State of Wyoming | 6,629 | $25.9K | 0.00% | −26,233−79.8% | Reduced |
| Los Angeles Capital Management LLC | 6,430 | $25.1K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 3,100 | $12.1K | 0.00% | +880+39.6% | Added |
| Ameritas Investment Partners, Inc. | 2,520 | $9.85K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 1,634 | $6.39K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 1,376 | $5.38K | 0.00% | −11,657−89.4% | Reduced |
| Sterling Capital Management LLC | 911 | $3.56K | 0.00% | +814+839.2% | Added |
| The PNC Financial Services Group, Inc. | 738 | $2.89K | 0.00% | −433−37.0% | Reduced |
| GAMMA Investing LLC | 495 | $1.94K | 0.00% | +495 | New |
| Fortitude Family Office, LLC | 230 | $899 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 44 | $172 | 0.00% | +44 | New |
| SBI Securities Co., Ltd. | 27 | $106 | 0.00% | +5+22.7% | Added |
| Group One Trading, L.P. | 7 | $27 | 0.00% | −3,900−99.8% | Reduced |
| Caitong International Asset Management Co., Ltd | 5 | $20 | 0.00% | −13−72.2% | Reduced |
| SRS Capital Advisors, Inc. | 3 | $12 | 0.00% | +3 | New |
| Mariner, LLC | 0 | $0 | 0.00% | −45,261−100.0% | Sold out |
| OrbiMed Advisors LLC | – | – | – | – | Not filed |
| Baker Bros. Advisors LP | – | – | – | – | Not filed |
| Ra Capital Management, L.P. | – | – | – | – | Not filed |
| Soleus Capital Management, L.P. | – | – | – | – | Not filed |
| Kynam Capital Management, LP | – | – | – | – | Not filed |
| Sphera Funds Management Ltd. | – | – | – | – | Not filed |
| Two Sigma Investments, LP | – | – | – | – | Not filed |
| ADAR1 Capital Management, LLC | – | – | – | – | Not filed |
| Millennium Management LLC | – | – | – | – | Not filed |
| Adage Capital Partners GP, L.L.C. | – | – | – | – | Not filed |
| Northern Trust Corp | – | – | – | – | Not filed |
| Goldman Sachs Group Inc | – | – | – | – | Not filed |
| Charles Schwab Investment Management Inc | – | – | – | – | Not filed |
| Bridgeway Capital Management, LLC | – | – | – | – | Not filed |
| Graham Capital Management, L.P. | – | – | – | – | Not filed |
| Wells Fargo & Company | – | – | – | – | Not filed |
| Bank of America Corp | – | – | – | – | Not filed |
| Price T Rowe Associates Inc | – | – | – | – | Not filed |
| Citadel Advisors LLC | – | – | – | – | Not filed |
| ExodusPoint Capital Management, LP | – | – | – | – | Not filed |
| New York State Common Retirement Fund | – | – | – | – | Not filed |
| HSBC Holdings PLC | – | – | – | – | Not filed |
| Mangrove Partners | – | – | – | – | Not filed |
| Mirae Asset Global ETFs Holdings Ltd. | – | – | – | – | Not filed |
| Gsa Capital Partners LLP | – | – | – | – | Not filed |
| Alliancebernstein L.P. | – | – | – | – | Not filed |
| Legal & General Group Plc | – | – | – | – | Not filed |
| Royal Bank of Canada | – | – | – | – | Not filed |
| Tower Research Capital LLC (TRC) | – | – | – | – | Not filed |
| Quarry LP | – | – | – | – | Not filed |
| Optiver Holding B.V. | – | – | – | – | Not filed |