Prelude Therapeutics Inc
PRLD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001678660
No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Prelude Therapeutics Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 75
- +21 vs. Q1 2026
- Shares held
- 49.6M
- +18.8M (+61.2%) vs. Q1 2026
- Total value
- $264.3M
- +$159.1M (+151.2%) vs. Q1 2026
- New holders
- 34
- 25 more added
- Sold out
- 13
- 8 more reduced
1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 75 | $264.3M |
| Q1 2026 | 55 | $105.2M |
| Q4 2025 | 48 | $82.6M |
| Q3 2025 | 47 | $39.1M |
| Q2 2025 | 50 | $22.0M |
| Q1 2025 | 59 | $23.3M |
| Q4 2024 | 62 | $41.0M |
| Q3 2024 | 70 | $74.0M |
| Q2 2024 | 61 | $129.2M |
| Q1 2024 | 58 | $162.1M |
| Q4 2023 | 56 | $148.3M |
| Q3 2023 | 60 | $113.1M |
| Q2 2023 | 55 | $176.2M |
| Q1 2023 | 55 | $179.6M |
| Q4 2022 | 60 | $188.3M |
| Q3 2022 | 53 | $210.3M |
| Q2 2022 | 62 | $170.9M |
| Q1 2022 | 68 | $235.4M |
| Q4 2021 | 75 | $437.6M |
| Q3 2021 | 61 | $1.12B |
| Q2 2021 | 57 | $986.6M |
| Q1 2021 | 60 | $1.41B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| OrbiMed Advisors LLC | 13,724,571 | $73.2M | 1.39% | +2,815,315+25.8% | Added |
| Baker Bros. Advisors LP | 10,123,824 | $54.0M | 0.27% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 6,475,882 | $34.5M | 0.30% | +6,475,882 | New |
| Soleus Capital Management, L.P. | 3,378,378 | $18.0M | 0.62% | +3,378,378 | New |
| Kynam Capital Management, LP | 2,415,087 | $12.9M | 0.71% | +822,536+51.6% | Added |
| Vanguard Capital Management LLC | 2,009,445 | $10.7M | 0.00% | +779,039+63.3% | Added |
| BlackRock, Inc. | 1,797,501 | $9.58M | 0.00% | +1,475,615+458.4% | Added |
| Sphera Funds Management Ltd. | 1,019,832 | $5.44M | 0.78% | +461,493+82.7% | Added |
| Two Sigma Investments, LP | 993,369 | $5.29M | 0.00% | +69,743+7.6% | Added |
| ADAR1 Capital Management, LLC | 900,900 | $4.80M | 0.23% | +748,075+489.5% | Added |
| Millennium Management LLC | 844,993 | $4.50M | 0.00% | +462,256+120.8% | Added |
| Geode Capital Management, LLC | 841,862 | $4.49M | 0.00% | +539,404+178.3% | Added |
| Adage Capital Partners GP, L.L.C. | 766,095 | $4.08M | 0.01% | +766,095 | New |
| Acadian Asset Management LLC | 611,359 | $3.25M | 0.00% | +99,840+19.5% | Added |
| Morgan Stanley | 503,860 | $2.69M | 0.00% | +181,699+56.4% | Added |
| State Street Corp | 428,787 | $2.29M | 0.00% | +290,556+210.2% | Added |
| UBS Group AG | 318,797 | $1.70M | 0.00% | +254,292+394.2% | Added |
| Vanguard Fiduciary Trust Co | 284,886 | $1.52M | 0.00% | +127,506+81.0% | Added |
| Renaissance Technologies LLC | 281,200 | $1.50M | 0.00% | +6,000+2.2% | Added |
| Northern Trust Corp | 240,599 | $1.28M | 0.00% | +190,479+380.0% | Added |
| Vanguard Portfolio Management LLC | 193,920 | $1.03M | 0.00% | +193,920 | New |
| Marshall Wace, LLP | 190,692 | $1.02M | 0.00% | −168,214−46.9% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 125,606 | $669.5K | 0.00% | +16,521+15.1% | Added |
| Goldman Sachs Group Inc | 120,834 | $644.0K | 0.00% | −115,635−48.9% | Reduced |
| Hillsdale Investment Management Inc. | 81,400 | $433.9K | 0.01% | +81,400 | New |
| Bank of New York Mellon Corp | 68,187 | $363.4K | 0.00% | +68,187 | New |
| Charles Schwab Investment Management Inc | 67,622 | $360.4K | 0.00% | +67,622 | New |
| Bridgeway Capital Management, LLC | 64,500 | $343.8K | 0.01% | +11,000+20.6% | Added |
| Squarepoint Ops LLC | 59,540 | $317.3K | 0.00% | +59,540 | New |
| Panagora Asset Management Inc | 47,574 | $253.6K | 0.00% | +47,574 | New |
| Mariner, LLC | 45,261 | $241.2K | 0.00% | +45,261 | New |
| Nuveen, LLC | 37,023 | $197.3K | 0.00% | +37,023 | New |
| Dimensional Fund Advisors LP | 35,210 | $186.8K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 34,742 | $185.2K | 0.00% | +34,742 | New |
| Cerity Partners LLC | 32,875 | $175.2K | 0.00% | 00.0% | Unchanged |
| State of Wyoming | 32,862 | $175.2K | 0.02% | +32,862 | New |
| Graham Capital Management, L.P. | 29,770 | $158.7K | 0.00% | +18,427+162.5% | Added |
| Deutsche Bank AG | 27,824 | $148.3K | 0.00% | +27,824 | New |
| Wells Fargo & Company | 25,325 | $135.0K | 0.00% | +25,325 | New |
| Bank of America Corp | 23,875 | $127.3K | 0.00% | −32,650−57.8% | Reduced |
| Price T Rowe Associates Inc | 22,758 | $122.0K | 0.00% | +22,758 | New |
| Citadel Advisors LLC | 22,554 | $120.2K | 0.00% | −101,824−81.9% | Reduced |
| Rhumbline Advisers | 22,074 | $117.6K | 0.00% | +22,074 | New |
| Vanguard Global Advisers, LLC | 16,210 | $86.4K | 0.00% | +11,574+249.7% | Added |
| ExodusPoint Capital Management, LP | 15,475 | $82.5K | 0.00% | +15,475 | New |
| Barclays PLC | 14,529 | $77.4K | 0.00% | +5,929+68.9% | Added |
| New York State Common Retirement Fund | 14,200 | $75.7K | 0.00% | +14,200 | New |
| HSBC Holdings PLC | 13,652 | $74.4K | 0.00% | 00.0% | Unchanged |
| Mangrove Partners | 13,352 | $71.2K | 0.00% | +13,352 | New |
| Qube Research & Technologies Ltd | 13,110 | $69.9K | 0.00% | −3,307−20.1% | Reduced |
| Citigroup Inc | 13,033 | $69.5K | 0.00% | +13,028+260,560.0% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 12,784 | $68.1K | 0.00% | +12,784 | New |
| Gsa Capital Partners LLP | 12,672 | $68.0K | 0.00% | +12,672 | New |
| JPMorgan Chase & Co | 13,538 | $66.7K | 0.00% | +13,476+21,735.5% | Added |
| Spark Investment Management LLC | 10,600 | $56.5K | 0.11% | +10,600 | New |
| Police & Firemen's Retirement System of New Jersey | 10,492 | $55.9K | 0.00% | +10,492 | New |
| Alliancebernstein L.P. | 10,530 | $36.0K | 0.00% | +10,530 | New |
| Los Angeles Capital Management LLC | 6,430 | $34.3K | 0.00% | +6,430 | New |
| FMR LLC | 5,629 | $30.0K | 0.00% | −380−6.3% | Reduced |
| STRS Ohio | 5,500 | $29.3K | 0.00% | +5,500 | New |
| BNP Paribas Arbitrage, SA | 4,104 | $21.9K | 0.00% | +4,009+4,220.0% | Added |
| Group One Trading, L.P. | 3,907 | $20.8K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 2,699 | $14.4K | 0.00% | +2,699 | New |
| Royal Bank of Canada | 2,658 | $14.0K | 0.00% | +327+14.0% | Added |
| Ameritas Investment Partners, Inc. | 2,520 | $13.4K | 0.00% | +2,520 | New |
| Tower Research Capital LLC (TRC) | 2,377 | $12.7K | 0.00% | +2,377 | New |
| Russell Investments Group, Ltd. | 2,220 | $11.8K | 0.00% | +2,220 | New |
| Nisa Investment Advisors, LLC | 1,634 | $8.71K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 1,171 | $6.24K | 0.00% | 00.0% | Unchanged |
| Quarry LP | 755 | $4.02K | 0.00% | +755 | New |
| Fortitude Family Office, LLC | 230 | $1.23K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 97 | $517 | 0.00% | +97 | New |
| SBI Securities Co., Ltd. | 22 | $117 | 0.00% | −2,619−99.2% | Reduced |
| Caitong International Asset Management Co., Ltd | 18 | $96 | 0.00% | +18 | New |
| Optiver Holding B.V. | 4 | $21 | 0.00% | −16−80.0% | Reduced |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −947,049−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −267,788−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −192,963−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −58,699−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −57,190−100.0% | Sold out |
| Colony Group, LLC | 0 | $0 | 0.00% | −50,007−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −32,700−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −17,420−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −16,329−100.0% | Sold out |
| Diametric Capital, LP | 0 | $0 | 0.00% | −11,980−100.0% | Sold out |
| Nine Masts Capital Ltd | 0 | $0 | 0.00% | −11,699−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −10,294−100.0% | Sold out |
| Caldwell Sutter Capital, Inc. | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| CWM, LLC | – | – | – | – | Not filed |