Prelude Therapeutics Inc

PRLD

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001678660

SEC filings (opens in a new tab)

Insider trades, last 90 days

None

No open-market purchases or sales were filed in the last 90 days.

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13F holders, Q2 2026

75

+20 vs. Q1 2026
Total value $264.34M

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Superinvestors holding PRLD

0

None of the superinvestors held PRLD at the end of Q2 2026.

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Price chart

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Latest insider trades

Open-market purchases and sales by PRLD insiders, newest first.

Insider trades
Filed (ET)	Trade date	Insider	Transaction	Shares	Avg price	Value	Shares after	Holding change	Filing
Apr 23, 20266:48 PM ET	Apr 21, 2026	ORBIMED ADVISORS LLC and 3 othersDirector, 10% Owner	PPurchaseCommon Stock	+2.82M	$4.44	+$12.5M	1.13M	New position	SEC
Apr 23, 2026	Apr 21, 2026	Bonita David PDirector, 10% Owner	PPurchaseCommon Stock	+2.82M	$4.44	+$12.5M	1.13M	New position	SEC
Apr 22, 20264:15 PM ET	Apr 21, 2026	BAKER JULIAN and 5 othersDirector, 10% Owner	PPurchaseCommon Stock · Derivative	+2.25M	$4.4399	+$10M	20.11M	–	SEC
Mar 27, 2025	Mar 25, 2025	Combs AndrewChief Chemistry Officer	PPurchaseCommon Stock	+100K	$0.69	+$69K	480.12K	+26.3%	SEC
Mar 27, 2025	Mar 25, 2025	Vaddi KrishnaCEO	PPurchaseCommon Stock	+675K	$0.69	+$465.75K	2M	+51.0%	SEC

Top 5 13F holders, Q2 2026

The largest institutional positions in PRLD at the end of Q2 2026.

Institutions holding PRLD in Q2 2026
Institution	Shares	Value	% of portfolio	Change in shares	Action
ORBIMED ADVISORS LLC	13,724,571	$73.15M	1.39%	+2,815,315+25.8%	Added
BAKER BROS. ADVISORS LP	10,123,824	$53.96M	0.27%	00.0%	Unchanged
RA CAPITAL MANAGEMENT, L.P.	6,475,882	$34.52M	0.30%	+6,475,882	New
Soleus Capital Management, L.P.	3,378,378	$18.01M	0.62%	+3,378,378	New
Kynam Capital Management, LP	2,415,087	$12.87M	0.71%	+822,536+51.6%	Added