Prelude Therapeutics Inc
PRLD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001678660
No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.
Holders of 5% or more of PRLD
Holders whose latest Schedule 13D or 13G filing reports 5% or more of Prelude Therapeutics Inc, largest stake first. The change is against the holder's previous filing.
| Holder | Latest form | Stake | Change | First filed | Latest filing | Filing |
|---|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 13D/A | 23.50%10.3M shares | – | Jun 13, 20251 filing | Jun 13, 2025 | SEC |
| Vaddi Krishna | 13G/A | 13.15%6.75M shares | −0.65 ppfrom 13.80% | Feb 14, 20253 filings | Feb 13, 2026 | SEC |
| Incyte Corp | 13G | 9.90%4.37M shares | New | Nov 7, 20251 filing | Nov 7, 2025 | SEC |
Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.
13D and 13G filings
6 Schedule 13D and 13G filings on Prelude Therapeutics Inc, newest first, including old-format filings without a stake.
| Filed (ET) | Filer | Form | Stake | Change | Event date | Filing |
|---|---|---|---|---|---|---|
| Feb 13, 20264:02 PM ET | Vaddi Krishna | 13G/A | 13.15%6.75M shares | −0.65 ppfrom 13.80% | Dec 31, 2025 | SEC |
| Nov 7, 20254:01 PM ET | Incyte Corp | 13G | 9.90%4.37M shares | New | Nov 3, 2025 | SEC |
| Jun 13, 20255:21 PM ET | Baker Bros. Advisors LPand 3 others | 13D/A | 23.50%10.3M shares | – | Jun 12, 2025 | SEC |
| May 15, 20255:20 PM ET | Vaddi Krishna | 13G/A | 13.80%6.40M shares | +4.30 ppfrom 9.50% | Mar 31, 2025 | SEC |
| Feb 14, 20254:19 PM ET | Vaddi Krishna | 13G/A | 9.50%5.49M shares | – | Dec 31, 2024 | SEC |
| Feb 13, 20258:58 AM ET | Flynn James Eand 3 others | 13G/A | 0.00%0 shares | –Below 5% | Dec 31, 2024 | SEC |
Form 144: proposed insider sales
Notices from officers, directors and other affiliates planning to sell Prelude Therapeutics Inc shares.
No Form 144 notices for Prelude Therapeutics Inc are on file.