| Apr 23, 20266:48 PM ET | Apr 21, 2026 | ORBIMED ADVISORS LLC and 3 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +2.82M | $4.44 | +$12.5M | 1.13M | New position | SEC↗ |
| Apr 23, 2026 | Apr 21, 2026 | Bonita David PDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +2.82M | $4.44 | +$12.5M | 1.13M | New position | SEC↗ |
| Apr 22, 20264:15 PM ET | Apr 21, 2026 | BAKER JULIAN and 5 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock · Derivative | +2.25M | $4.4399 | +$10M | 20.11M | – | SEC↗ |
| Mar 27, 2025 | Mar 25, 2025 | Combs AndrewChief Chemistry Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +100K | $0.69 | +$69K | 480.12K | +26.3% | SEC↗ |
| Mar 27, 2025 | Mar 25, 2025 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +675K | $0.69 | +$465.75K | 2M | +51.0% | SEC↗ |
| Mar 24, 2025 | Mar 20 – Mar 21, 2025 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +20.42K | $0.73 | +$14.9K | 1.32M | +1.6% | SEC↗ |
| Mar 18, 2025 | Mar 14 – Mar 17, 2025 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +39.11K | $0.75 | +$29.33K | 1.3M | +3.1% | SEC↗ |
| Mar 14, 2025 | Mar 12 – Mar 13, 2025 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +97.5K | $0.7151 | +$69.73K | 1.26M | +8.4% | SEC↗ |
| Jan 3, 2025 | Dec 31, 2024 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +5K | $1.21 | +$6.05K | 142.55K | +3.6% | SEC↗ |
| Jan 2, 2025 | Dec 30, 2024 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +10K | $1.20 | +$12K | 137.55K | +7.8% | SEC↗ |
| Dec 26, 2024 | Dec 20 – Dec 23, 2024 | Combs AndrewChief Chemistry Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +63.08K | $1.3593 | +$85.74K | 377.62K | +20.1% | SEC↗ |
| Dec 20, 2024 | Dec 19, 2024 | Lim Bryant DavidCLO, Interim CFO, Corp Sec. | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +25K | $0.91 | +$22.75K | 27.4K | +1,041.7% | SEC↗ |
| Dec 20, 2024 | Dec 18, 2024 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +100K | $0.93 | +$93K | 1.17M | +9.4% | SEC↗ |
| Dec 20, 2024 | Dec 19, 2024 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +6.89K | $0.89 | +$6.13K | 127.55K | +5.7% | SEC↗ |
| May 26, 2023 | May 24 – May 25, 2023 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +1.9K | $5.1521 | +$9.79K | 1.07M | +0.2% | SEC↗ |
| May 25, 2023 | May 24, 2023 | Lim Bryant DavidChief Legal Officer, Corp Sec. | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +2.4K | $5.39 | +$12.94K | 2.4K | New position | SEC↗ |
| May 25, 2023 | May 23, 2023 | Chardonnet LaurentChief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +5K | $5.50 | +$27.5K | 42.17K | +13.5% | SEC↗ |
| May 25, 2023 | May 23, 2023 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +11.86K | $5.63 | +$66.75K | 1.07M | +1.1% | SEC↗ |
| May 24, 20235:09 PM ET | May 22, 2023 | ORBIMED ADVISORS LLC and 2 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +869.57K | $5.75 | +$5M | 10.12M | +9.4% | SEC↗ |
| May 24, 2023 | May 22, 2023 | Bonita David PDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +869.57K | $5.75 | +$5M | 10.12M | +9.4% | SEC↗ |
| Apr 6, 2023 | Apr 6, 2023 | Huang JanePresident, CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −13.28K | $6.12 | −$81.27K | 24.22K | −35.4% | SEC↗ |
| Dec 21, 2022 | Dec 20, 2022 | Vaddi KrishnaCEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +19.19K | $5.13 | +$98.43K | 120.67K | +18.9% | SEC↗ |
| Dec 12, 2022 | Dec 8, 2022 | Chardonnet LaurentChief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +10K | $4.76 | +$47.6K | 35.87K | +38.7% | SEC↗ |
| Jun 1, 2022 | Jun 1, 2022 | Chardonnet LaurentChief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +10K | $4.23 | +$42.3K | 24.5K | +69.0% | SEC↗ |
| Dec 17, 2021 | Dec 15, 2021 | Morosini DeborahEVP, Chief of Clinical Affairs | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −28.75K | $13.00 | −$373.76K | 444 | −98.5% | SEC↗ |
| Dec 15, 2021 | Dec 13 – Dec 14, 2021 | Combs AndrewEVP, Head of Chemistry | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +8K | $11.86 | +$94.88K | 268.38K | +3.1% | SEC↗ |
| Nov 18, 2021 | Nov 16, 2021 | Morosini DeborahEVP, Chief of Clinical Affairs | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −28.75K | $15.8778 | −$456.5K | 444 | −98.5% | SEC↗ |
| Oct 6, 2021 | Oct 5, 2021 | Mauro David JChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −15K | $30.9557 | −$464.34K | 0 | −100.0% | SEC↗ |
| Sep 9, 2021 | Sep 7, 2021 | Mauro David JChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −15K | $36.685 | −$550.27K | 0 | −100.0% | SEC↗ |
| Sep 7, 2021 | Sep 2, 2021 | Pierce ChristopherEVP and Chief of Business Oper | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −17K | $41.6776 | −$708.52K | 3.75K | −81.9% | SEC↗ |
| Aug 30, 2021 | Aug 26 – Aug 27, 2021 | Scherle PeggyChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −7.71K | $35.7492 | −$275.77K | 172.92K | −4.3% | SEC↗ |
| Aug 27, 2021 | Aug 25, 2021 | Piper BrianChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −8.33K | $33.3403 | −$277.82K | 0 | −100.0% | SEC↗ |
| Aug 17, 2021 | Aug 13, 2021 | Scherle PeggyChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.29K | $35.07 | −$80.17K | 172.92K | −1.3% | SEC↗ |
| Aug 9, 2021 | Aug 5, 2021 | Mauro David JChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −15K | $31.094 | −$466.41K | 0 | −100.0% | SEC↗ |
| Jul 29, 2021 | Jul 27, 2021 | Scherle PeggyChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −20K | $35.4718 | −$709.44K | 172.92K | −10.4% | SEC↗ |
| Jul 8, 2021 | Jul 6, 2021 | Mauro David JChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −15K | $27.4757 | −$412.14K | 0 | −100.0% | SEC↗ |
