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OrbiMed Genesis GP LLC

In the past year, 3 open-market purchase filings worth $59.9M and 3 sale filings worth $52.4M.

Current role at each company

Show 17 more companies

Open-market trades in the past year

Open-market purchases (P) and sales (S) filed in the last 365 days, not counting derivative securities or duplicate filings. Values leave out price outliers.

Bought
$59.9M
3 filings
Sold
$52.4M
3 filings
Net
+$7.56M
Bought minus sold
Companies
4
With open-market trades

Trades

Every Form 4 that lists OrbiMed Genesis GP LLC as a reporting owner, including filings made jointly with others, grouped by company. Each row adds up one type of transaction in one filing. Only open-market purchases (P) and sales (S) are shown by default.

ETRA Electra Therapeutics, Inc.

Director, 10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Sep 23, 2026 (view filing)5:29 PM ETSep 212 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+1.33M$15.00+$20.0M+313.8%1.76M after2 lots

BRVE Braveheart Bio, Inc.

Director, 10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Aug 11, 2026 (view filing)5:27 PM ETAug 74 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+1.94M$18.00+$34.9MNew position273.3K after2 lots

ELVN Enliven Therapeutics, Inc.

10% Owner3 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jun 24, 2026 (view filing)7:19 PM ETJun 222 daysOrbiMed Advisors LLC and 2 others10% OwnerSSale−860.1K$45.36−$39.0M−11.6%6.56M after4 lots
Jun 17, 2026 (view filing)7:45 PM ETJun 152 daysOrbiMed Advisors LLC and 2 others10% OwnerSSale−281.4K$45.02−$12.7M−3.7%7.39M after2 lots
May 20, 2024 (view filing)5:00 PM ETMay 164 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerSSale−1.03M$22.14−$22.9M−11.9%7.66M after2 lotsDuplicate filing

STTK Shattuck Labs, Inc.

Director3 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jun 15, 2026 (view filing)6:12 PM ETJun 114 daysOrbiMed Advisors LLC and 2 othersDirectorPPurchase+1.25M–––5.30M afterDerivative2 lotsDuplicate filing
Sep 2, 2025 (view filing)9:52 PM ETAug 258 daysLateOrbiMed Advisors LLC and 2 othersDirectorPPurchase+6.31M$0.8677+$5.47MNew position1.05M after2 lots
Sep 2, 2025 (view filing)9:52 PM ETAug 258 daysLateOrbiMed Advisors LLC and 2 othersDirectorPPurchase+30.6M–––3.07M afterDerivative4 lotsDuplicate filing

QTTB Q32 Bio Inc.

Director, 10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jun 1, 2026 (view filing)9:13 PM ETMay 284 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+1.88M$8.00+$15.0MNew position625.0K after2 lotsDuplicate filing

PRLD Prelude Therapeutics Inc

Director, 10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Apr 23, 2026 (view filing)6:48 PM ETApr 212 daysOrbiMed Advisors LLC and 3 othersDirector, 10% OwnerPPurchase+2.82M$4.44+$12.5MNew position1.13M after2 lotsDuplicate filing

IMA ImageneBio, Inc.

Director2 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Apr 16, 2026 (view filing)7:23 PM ETApr 142 daysOrbiMed Advisors LLC and 2 othersDirectorPPurchase+721.3K–––384.7K afterDerivative2 lotsDuplicate filing
Jun 24, 2022 (view filing)5:39 PM ETJun 22-242 daysOrbiMed Advisors LLC and 2 othersDirectorPPurchase−252.2K$4.47−$1.13M−10.7%2.10M after4 lotsDuplicate filing

ACET Adicet Bio, Inc.

10% Owner4 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Apr 9, 2026 (view filing)5:38 PM ETApr 7-82 daysOrbiMed Advisors LLC and 7 others10% OwnerSSale−104.7K$6.45−$674.8K−100.0%0 after4 lots
Oct 10, 2025 (view filing)8:06 PM ETOct 82 daysOrbiMed Advisors LLC and 7 others10% OwnerPPurchase+5.00M$1.00+$5.00MNew position4.49M after2 lots
Jan 26, 2024 (view filing)7:14 PM ETJan 251 dayOrbiMed Advisors LLC and 7 othersDirector, 10% OwnerPPurchase+3.13M$2.40+$7.50MNew position1.26M after3 lotsDuplicate filing
Jun 29, 2023 (view filing)4:46 PM ETJun 272 daysOrbiMed Advisors LLC and 8 othersDirector, 10% OwnerPPurchase+875.0K$2.09+$1.83MNew position748.1K after4 lotsDuplicate filing

CMPX Compass Therapeutics, Inc.

Director, 10% Owner5 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Apr 11, 2025 (view filing)7:24 PM ETApr 92 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerSSale−3.57M$1.59−$5.68M−100.0%0 afterDuplicate filing
Nov 10, 2022 (view filing)4:44 PM ETNov 82 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+402.0K$3.21+$1.29M+2.7%15.2M afterDuplicate filing
May 13, 2022 (view filing)5:45 PM ETMay 11-132 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+192.5K$2.18+$420.5K+1.3%14.8M after3 lotsDuplicate filing
May 10, 2022 (view filing)6:21 PM ETMay 6-104 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+125.4K$1.57+$197.3K+0.9%14.6M after3 lotsDuplicate filing
Nov 8, 2021 (view filing)9:06 PM ETNov 44 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+5.36M$3.50+$18.8MNew position3.57M after2 lotsDuplicate filing

EWTX Edgewise Therapeutics, Inc.

Director, 10% Owner4 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Apr 4, 2025 (view filing)7:33 PM ETApr 31 dayOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+496.8K$20.13+$10.0MNew position443.8K after2 lotsDuplicate filing
Jan 25, 2024 (view filing)4:28 PM ETJan 232 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+454.5K$11.00+$5.00M+3.3%14.4M afterDuplicate filing
Sep 16, 2022 (view filing)4:31 PM ETSep 16Same dayOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+484.5K$10.32+$5.00M+3.6%14.0M afterDuplicate filing
May 20, 2022 (view filing)4:38 PM ETMay 182 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+138.0K$7.21+$995.0K+1.0%13.5M afterDuplicate filing

IRON Disc Medicine, Inc.

Director8 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Mar 26, 2025 (view filing)7:00 PM ETMar 242 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−5.74K$54.11−$310.5K−3.0%186.5K after3 lotsDuplicate filing
Mar 21, 2025 (view filing)8:00 PM ETMar 19-212 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−52.4K$54.02−$2.83M−21.9%187.3K after9 lotsDuplicate filing
Mar 12, 2025 (view filing)9:34 PM ETMar 10-122 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−312.4K$54.31−$17.0M−61.7%194.2K after15 lotsDuplicate filing
Jun 20, 2024 (view filing)5:19 PM ETJun 173 daysOrbiMed Advisors LLC and 3 othersDirectorPPurchase+83.3K$36.00+$3.00M+54.8%235.4K after3 lotsDuplicate filing
Dec 20, 2023 (view filing)6:28 PM ETDec 182 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−1.72K$59.24−$102.1K−100.0%0 afterDuplicate filing
Dec 15, 2023 (view filing)6:04 PM ETDec 141 dayOrbiMed Advisors LLC and 3 othersDirectorSSale−433.2K$56.75−$24.6M−65.9%224.4K after3 lotsDuplicate filing
Dec 14, 2023 (view filing)5:44 PM ETDec 12-142 daysOrbiMed Advisors LLC and 3 othersDirectorSSale−134.2K$58.88−$7.90M−15.6%727.8K after8 lotsDuplicate filing
Feb 17, 2023 (view filing)4:43 PM ETFeb 152 daysOrbiMed Advisors LLC and 3 othersDirector, 10% OwnerPPurchase+108.7K$23.00+$2.50M+57.1%299.2K after3 lotsDuplicate filing

MBX MBX Biosciences, Inc.

Director, 10% Owner2 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Feb 19, 2025 (view filing)5:52 PM ETFeb 14-185 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+190.7K$10.60+$2.02M+34.2%747.9K after4 lotsDuplicate filing
Sep 17, 2024 (view filing)8:13 PM ETSep 161 dayOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+750.0K$16.00+$12.0MNew position653.8K after2 lotsDuplicate filing

KROS Keros Therapeutics, Inc.

Director1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Aug 15, 2024 (view filing)5:01 PM ETAug 132 daysOrbiMed Advisors LLC and 2 othersDirectorSSale−250.0K$44.01−$11.0M−67.7%119.5K after2 lotsDuplicate filing

SCPH scPharmaceuticals Inc.

10% Owner2 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Aug 15, 2024 (view filing)4:51 PM ETAug 132 daysOrbiMed Advisors LLC and 2 others10% OwnerPPurchase+500.0K$4.00+$2.00MNew position252.9K after2 lots
Nov 29, 2022 (view filing)4:36 PM ETNov 254 daysOrbiMed Advisors LLC and 2 others10% OwnerPPurchase+762.4K$5.25+$4.00M+16.7%5.33M after

TERN Terns Pharmaceuticals, Inc.

Director, 10% Owner4 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jul 17, 2024 (view filing)8:48 PM ETJul 15-162 daysOrbiMed Advisors LLC and 4 othersDirector, 10% OwnerSSale−56.2K$10.00−$561.6K−6.9%755.6K after6 lots10b5-1Duplicate filing
Dec 28, 2022 (view filing)5:57 PM ETDec 235 daysOrbiMed Advisors LLC and 4 othersDirector, 10% OwnerPPurchase+137.9K$7.25+$1.00M+2.9%4.88M afterDuplicate filing
Aug 18, 2022 (view filing)5:00 PM ETAug 162 daysOrbiMed Advisors LLC and 4 othersDirector, 10% OwnerPPurchase+3.69M$2.42+$8.93MNew position762.4K after3 lotsDuplicate filing
Aug 18, 2022 (view filing)5:00 PM ETAug 162 daysOrbiMed Advisors LLC and 4 othersDirector, 10% OwnerPPurchase+310.0K–––64.0K afterDerivative3 lotsDuplicate filing

ALPN Alpine Immune Sciences, Inc.

Director2 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Dec 29, 2023 (view filing)4:18 PM ETDec 27-282 daysOrbiMed Advisors LLC and 2 othersDirectorSSale−1.55M$18.54−$28.7M−85.4%264.3K after6 lotsDuplicate filing
Sep 21, 2021 (view filing)6:42 PM ETSep 174 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+1.01M$9.40+$9.50MNew position425.5K after2 lotsDuplicate filing

PMVP PMV Pharmaceuticals, Inc.

10% Owner3 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Nov 24, 2023 (view filing)4:38 PM ETNov 222 daysOrbiMed Advisors LLC and 2 others10% OwnerSSale−87.8K$2.23−$195.8K−100.0%0 after
May 31, 2022 (view filing)4:36 PM ETMay 265 daysOrbiMed Advisors LLC and 2 others10% OwnerSSale−26.3K$15.93−$418.2K−23.0%87.8K after
Mar 31, 2022 (view filing)5:30 PM ETMar 29-312 daysOrbiMed Advisors LLC and 3 others10% OwnerSSale−474.5K$21.63−$10.3M−100.0%0 after3 lots

DMRA Damora Therapeutics, Inc.

10% Owner7 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Aug 17, 2023 (view filing)4:40 PM ETAug 152 daysOrbiMed Advisors LLC and 4 others10% OwnerSSale−822.7K$0.75−$617.0K−35.3%1.51M after3 lots
Aug 2, 2023 (view filing)5:05 PM ETJul 312 daysOrbiMed Advisors LLC and 4 others10% OwnerSSale−209.4K$3.00−$628.2K−9.0%2.11M after3 lots
Jul 27, 2023 (view filing)4:28 PM ETJul 252 daysOrbiMed Advisors LLC and 4 others10% OwnerSSale−39.2K$2.92−$114.5K−1.7%2.26M after3 lots
Jul 17, 2023 (view filing)4:13 PM ETJul 134 daysOrbiMed Advisors LLC and 4 others10% OwnerSSale−194.7K$2.40−$467.3K−7.8%2.29M after3 lots
Apr 17, 2023 (view filing)5:28 PM ETApr 13-174 daysOrbiMed Advisors LLC and 4 others10% OwnerSSale−68.5K$1.87−$128.3K−2.8%2.42M after9 lots
Apr 12, 2023 (view filing)6:44 PM ETApr 10-122 daysOrbiMed Advisors LLC and 4 others10% OwnerSSale−67.5K$1.80−$121.4K−2.7%2.46M after9 lots
Apr 7, 2023 (view filing)4:42 PM ETApr 5-62 daysOrbiMed Advisors LLC and 4 others10% OwnerSSale−102.6K$2.16−$222.0K−3.9%2.51M after6 lots

THRX Theseus Pharmaceuticals, Inc.

Director, 10% Owner5 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jul 19, 2023 (view filing)4:15 PM ETJul 172 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+479.9K$3.05+$1.46M+281.2%650.6K after2 lotsDuplicate filing
Nov 9, 2022 (view filing)4:25 PM ETNov 72 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+192.0K$5.21+$1.00M+1.2%16.7M afterDuplicate filing
Jan 21, 2022 (view filing)7:18 PM ETJan 19-212 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+158.4K$9.97+$1.58M+1.0%16.5M after3 lotsDuplicate filing
Jan 13, 2022 (view filing)7:18 PM ETJan 11-132 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+44.7K$9.90+$442.8K+0.3%16.4M after4 lotsDuplicate filing
Oct 14, 2021 (view filing)5:00 PM ETOct 122 daysOrbiMed Advisors LLC and 2 othersDirector, 10% OwnerPPurchase+625.0K$16.00+$10.0MNew position499.1K after2 lotsDuplicate filing

KNTE Kinnate Biopharma Inc.

Director, 10% Owner3 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
May 8, 2023 (view filing)5:22 PM ETMay 4-54 daysOrbiMed Advisors LLC and 6 othersDirector, 10% OwnerPPurchase+1.46M$2.80+$4.09MNew position1.37M after5 lotsDuplicate filing
May 2, 2023 (view filing)9:34 PM ETApr 28-May 24 daysOrbiMed Advisors LLC and 6 othersDirector, 10% OwnerPPurchase+1.41M$2.61+$3.67MNew position794.4K after9 lotsDuplicate filing
Feb 15, 2022 (view filing)9:42 PM ETFeb 11-154 daysOrbiMed Advisors LLC and 3 othersDirectorPPurchase+195.7K$10.17+$1.99M+5.9%3.51M after4 lotsDuplicate filing

1 more company has matching trades: