| Sep 15, 20264:30 PM ET | Sep 11, 2026 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −27.14K | $70.11 | −$1.9M | 0 | −100.0% | SEC↗ |
| Sep 9, 20264:23 PM ET | Sep 4, 2026 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −1.69K | $79.96 | −$135.05K | 13.43K | −11.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 3, 20265:43 PM ET | Sep 1 – Sep 3, 2026 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −54.5K | $80.1517 | −$4.37M | 13.45K | −80.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 26, 20268:10 PM ET | Aug 24 – Aug 25, 2026 | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −9.1K | $83.0972 | −$755.85K | 54.32K | −14.3% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 18, 20266:56 PM ET | Aug 17, 2026 | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −33K | $79.151 | −$2.61M | 226.06K | −12.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 14, 20267:14 PM ET | Aug 12, 2026 | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −804 | $82.6425 | −$66.44K | 54.32K | −1.5% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 7, 20265:32 PM ET | Aug 6, 2026 | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5K | $80.00 | −$400K | 52.32K | −8.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 14, 20266:32 PM ET | Jul 13, 2026 | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −33K | $74.963 | −$2.47M | 226.06K | −12.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 9, 20267:35 PM ET | Jul 7, 2026 | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −100 | $82.50 | −$8.25K | 54.32K | −0.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 30, 2026 | Jun 26 – Jun 29, 2026 | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.5K | $75.00 | −$187.5K | 52.17K | −4.6% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 30, 2026 | Jun 26, 2026 | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −300 | $72.50 | −$21.75K | 54.32K | −0.5% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 24, 2026 | Jun 22, 2026 | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −9.7K | $72.66 | −$704.8K | 54.32K | −15.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 23, 2026 | Jun 18, 2026 | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −7.5K | $70.2205 | −$526.65K | 52.17K | −12.6% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 23, 2026 | Jun 18, 2026 | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −34K | $70.2155 | −$2.39M | 226.06K | −13.1% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 18, 2026 | Jun 16, 2026 | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −18.61K | $69.1938 | −$1.29M | 54.32K | −25.5% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 15, 2026 | Apr 13, 2026 | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5.73K | $66.3849 | −$380.45K | 79.48K | −6.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 15, 2026 | Apr 13 – Apr 14, 2026 | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −6.66K | $69.2256 | −$460.83K | 64.33K | −9.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 4, 2026 | Mar 2, 2026 | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −7.38K | $65.8802 | −$486.06K | 85.21K | −8.0% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 27, 2026 | Feb 25, 2026 | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −353 | $69.06 | −$24.38K | 70.99K | −0.5% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 19, 2026 | Feb 17 – Feb 18, 2026 | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −11.16K | $64.5153 | −$719.73K | 71.34K | −13.5% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 17, 2026 | Feb 17, 2026 | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.85K | $62.86 | −$179.34K | 52.17K | −5.2% | SEC↗ |
| Feb 17, 2026 | Feb 17, 2026 | Stephenson PamelaChief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5.53K | $62.86 | −$347.68K | 81K | −6.4% | SEC↗ |
| Feb 17, 2026 | Feb 17, 2026 | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −3.26K | $62.86 | −$204.67K | 92.59K | −3.4% | SEC↗ |
| Feb 17, 2026 | Feb 17, 2026 | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −3.23K | $62.86 | −$203.1K | 54.32K | −5.6% | SEC↗ |
| Feb 17, 2026 | Feb 17, 2026 | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −13.26K | $62.86 | −$833.78K | 226.06K | −5.5% | SEC↗ |
| Jan 21, 2026 | Jan 20, 2026 | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −1K | $69.74 | −$69.74K | 37.79K | −2.6% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 5, 2026 | Jan 2, 2026 | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −6.5K | $78.6845 | −$511.45K | 37.79K | −14.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 18, 2025 | Dec 17, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −754 | $91.47 | −$68.97K | 14.01K | −5.1% | SEC↗ |
| Dec 16, 2025 | Dec 15, 2025 | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −13.09K | $91.2244 | −$1.19M | 75.7K | −14.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 16, 2025 | Dec 12 – Dec 16, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −177.12K | $91.5497 | −$16.22M | 14.16K | −92.6% | SEC↗ |
| Dec 16, 2025 | Dec 15, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −7K | $91.87 | −$643.09K | 0 | −100.0% | SEC↗ |
| Dec 15, 2025 | Dec 11, 2025 | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −40K | $93.0497 | −$3.72M | 171.83K | −18.9% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 13, 2025 | Nov 11, 2025 | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −30K | $84.6982 | −$2.54M | 40.56K | −42.5% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 24, 20254:01 PM ET | Oct 22, 2025 | Blavatnik Len and 3 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −744.05K | $80.47 | −$59.87M | 2.81M | −20.9% | SEC↗ |
| Oct 17, 2025 | Oct 15 – Oct 17, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −93.59K | $85.9673 | −$8.05M | 385.55K | −19.5% | SEC↗ |
| Oct 9, 2025 | Oct 7 – Oct 8, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −90K | $70.1389 | −$6.31M | 500.62K | −15.2% | SEC↗ |
| Aug 26, 2025 | Aug 22, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.29K | $61.03 | −$139.58K | 590.62K | −0.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 15, 2025 | Aug 13 – Aug 14, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −32.17K | $61.1141 | −$1.97M | 592.91K | −5.1% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 7, 2025 | Aug 5, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −395 | $60.95 | −$24.08K | 625.08K | −0.1% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 1, 2025 | Jul 30, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −8.49K | $61.04 | −$518.35K | 625.48K | −1.3% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 25, 2025 | Jul 23 – Jul 24, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −42.87K | $61.0308 | −$2.62M | 633.97K | −6.3% | SEC↗ |
| Jul 22, 2025 | Jul 18, 2025 | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −664 | $61.13 | −$40.59K | 676.84K | −0.1% | SEC↗ |
| Jul 18, 2025 | Jul 17, 2025 | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.03K | $59.00 | −$119.83K | 63.5K | −3.1% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 14, 2025 | Jul 10, 2025 | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2K | $57.50 | −$115K | 65.53K | −3.0% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 11, 2025 | Jul 9, 2025 | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −34.8K | $55.3301 | −$1.93M | 161.83K | −17.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 8, 2025 | Jul 3, 2025 | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5.2K | $55.09 | −$286.47K | 161.83K | −3.1% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 18, 2025 | Jun 16, 2025 | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2K | $52.26 | −$104.52K | 67.53K | −2.9% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 9, 2025 | Jun 6, 2025 | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −3K | $50.00 | −$149.8K | 56.73K | −5.0% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 22, 2025 | May 20, 2025 | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −6.68K | $50.04 | −$334.12K | 59.72K | −10.1% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2025 | May 2, 2025 | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.1K | $50.17 | −$105.36K | 66.4K | −3.1% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
